[Difficulties and mistakes in the diagnosis of abdominal tuberculosis in the practice of the general practitioner].

The relevance of the research is determined by the growth of cases of abdominal tuberculosis (AT), which is difficult to diagnose. AIM: Identify clinical features and possibilities of timely AT diagnosis. MATERIALS AND METHODS: Medical reports of 116 AT patients. The results of clinical, microbiological, immunological, radiological, endoscopic and morphological studies were analyzed. THE RESULTS: AT proceeded under the mask of ulcerative colitis and Crohn's disease (26.3%), alcoholic and biliary hepatitis (11.8%), lymphoproliferative and oncological diseases (61.8%), often generalized against the background of HIV-infection. The duration of the diagnostic search for disease verification exceeded 3 months due to incorrect (erroneous) interpretation of intoxication (26.3%) and radiological pattern in the lungs (23.7%), non - application and late application of laparoscopy (39.5%). CONCLUSION: When diagnosing AT, it is necessary to consider the peculiarities of its clinic and to conduct timely laparoscopy.

[Correction by 2-ethyl-6-methyl-3-hydroxypyridine succinate of the hepatotoxyc, caused at rats introduction tuberculostatics]. / Korrektsiia Meksidolom gepattoksichnosti, vyzyvaemoi u krys vvedeniem tuberkulostatikov.

Administration of toxic doses of means specific tuberculostatics chemotherapy to rats caused development of medicinal damages of liver, kidneys, and pancreas. Use of 2-ethyl-6-methyl-hydroxypyridine succinate (SEMOP) and S-adenosyl-L-methionine reduced manifestations of pathological effects of tuberculostatics an organism of laboratory animals. There was clear dose-dependence of SEMOP effects. The highest cytoprotective effect was observed at the SEMOP dose of 50 mg/kg. Antioxidant properties of SEMOP determined it membrane protective effects.

[The pharmacological and laser correction of disorders of the blood microcirculatory bed in myocardial ischemia]. / Farmakologicheskaia i lazernaia korrektsiia narushenii mikrogemotsirkuliatornogo rusla pri ishemii miokarda.

Microhemocirculatory changes in the ischemic myocardium concurrently exposed to low-intensive He-Ne laser, finoptin (145 micrograms/kg body weight) and perlinganit (25 micrograms/kg body weight) were experimentally studied in 50 Chinchilla rabbits. Drug and laser were daily used after 30-day inactivity for 7 days. There were anti-ischemic effects of He-Ne laser and perlinganit in increasing the number of functioning capillaries and in enhancing their functional activity. Microhemocirculatory changes induced by finoptin were less significant than those caused by perlinganit.