Morphometric Analysis of the Supraorbital Foramen and Notch in the Population of Bosnia and Herzegovina.

OBJECTIVE: The aim of this study was to learn about the morphological characteristics of the supraorbital foramen and to determine its precise position in relation to the surrounding anatomical landmarks in the adult population of Bosnia and Herzegovina. MATERIAL AND METHODS: For this purpose, 60 skulls from the Bosnia and Herzegovina population of known sex (32 males and 28 females), taken from the osteological collection of the Department of Human Anatomy of the Medical Faculty in Sarajevo, were subjected to morphological and morphometric analysis. Morphometric measurements were performed using a digital vernier caliper (Mitutoyo Corporation, Japan). RESULTS: The study showed that most supraorbital nerves exit the orbit through the supraorbital notch (73.8%) and the rest through the foramen (26.2%). Of this number, bilateral supraorbital notches were recorded in 58.33% of cases, a bilateral supraorbital foramen in 18.34% of cases, while in 23.33% of cases a notch was recorded on one side and a foramen on the contralateral side. Morphometric measurements performed to determine the exact position of the supraorbital foramen relative to the surrounding landmarks showed different values in males and females. An accessory foramen was also observed on the examined skulls in 16.67% of cases. CONCLUSION: Detailed knowledge of anatomical variations of the supraorbital foramen is required for safe and successful administration of regional anesthesia, in order to avoid iatrogenic nerve injuries during orbitofacial region surgery.

Melatonin Protects the Histologic Structure of the Uterus in Conditions of Zearalenone Intake.

Background: Zearalenone is a widely spread mycotoxin, contaminant of most cereal grains. It has uterotropic, estrogenic and anabolic activity in farm animals. The results are hormonal disbalances as hyperestrogenism, Zearalenone inhibits follicle-stimulating hormone production, thus supressing ovarian follicle development and ovulation. Also, it induces oxidative stress. Melatonin acts as a potent natural antioxidant and regulates the reproductive function by modification of steroidogenesis. Objective: The present study was conducted to provide detailed qualitative histological analysis of uterus of female rats treated with zearalenone and melatonin and contribute to better understanding of the topic. Methods: Forty adult, female Wistar rats were equally divided into five groups: Z group - zearalenone, 0,3 mg/kg, i.g.; M group - melatonin, 10 mg/kg, i.p.; ZM group -concomitant application of zearalenone and melatonin in the same dosing regimen, VZ group-zearalenone vehiculum/sunflower oil, i.g. and MZ group-melatonin vehiculum/5% ethanol in Ringer, i.p. Animals were treated daily for 28 consecutive days. After that period, all animals were sacrificed to obtain samples for qualitative histological analysis using the light microscope. Results: Zearalenone led to the alterations of the uterine structures, predominantly in the endometrium that were characterized by metaplasia and hypertrophy of the epithelial cells and hypercellularity of the stroma. In the myometrium, zearalenone induced hypertrophy and hyperplasia of the myocytes. Conclusion: Melatonin, when applied together with zearalenone, blocked the adverse effects of the zearalenone.

[Computer tomography study of the pterygopalatine fossa and its communications]. / Prikaz fossae pterygopalatinae i njenih komunikacija upotrebom kompjuterizovane tomografije.

Pterygopalatine fossa represents very important topographic area, which is connected, by numerous foramina and fissures, to the other extracranial and intracranial areas. This gives to it huge anatomic and clinical significance. In these papers, through the method of computed tomography in axial and coronal projections, we have presented pterygopalatine fossa and the communications that it can establish through foramen rotundum (the middle cranial fossa), inferior orbital fissure (orbital cavity), sphenopalatine foramen (nasal cavity), greater palatine foramen and lesser palatine foramina (oral cavity), canalis pterygoideusa (nasal part of throat) and pterygopalatine fissure (infratemporal fossa). Knowledge on pterygopalatine fossa, and its communications, too, is necessary for adequate evaluation of the infective and tumourous processes, by which it might be primarily or secondarily taken.