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J Am Acad Dermatol ; 39(5 Pt 2): 876-8, 1998 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-9810920

RESUMEN

Malignant melanoma presenting as an inflammatory skin metastasis has been described but is an exceedingly rare phenomenon. We report an unusual case of a patient who developed right leg lesions that were initially thought to be infectious in origin. There was no resolution of these lesions with antibiotic therapy, and the patient subsequently underwent an incisional biopsy that showed atypical S-100 positive cells within dermal vessels. On further questioning, the patient revealed that 20 years earlier she had a pigmented lesion removed from her right posterior calf. Review of that material revealed malignant melanoma, approximately 3.2 mm in depth. Although the patient was subsequently treated with a right groin lymph node dissection and isolated limb perfusion chemotherapy, she has continued to develop locally recurrent disease. This case is unusual both in terms of clinical presentation and interval of disease progression.


Asunto(s)
Melanoma/patología , Paniculitis/patología , Neoplasias Cutáneas/patología , Anciano , Antineoplásicos Alquilantes/administración & dosificación , Antineoplásicos Alquilantes/uso terapéutico , Biopsia , Quimioterapia del Cáncer por Perfusión Regional , Diagnóstico Diferencial , Progresión de la Enfermedad , Femenino , Humanos , Escisión del Ganglio Linfático , Metástasis Linfática/patología , Melanoma/tratamiento farmacológico , Melanoma/secundario , Melanoma/cirugía , Melfalán/administración & dosificación , Melfalán/uso terapéutico , Recurrencia Local de Neoplasia/patología , Proteínas S100/análisis , Enfermedades Cutáneas Infecciosas/diagnóstico , Neoplasias Cutáneas/tratamiento farmacológico , Neoplasias Cutáneas/cirugía , Vimentina/análisis
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