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1.
J Cardiothorac Surg ; 19(1): 537, 2024 Sep 20.
Artículo en Inglés | MEDLINE | ID: mdl-39304900

RESUMEN

Both anaesthesiologists and surgeons experience challenges in managing airway stenosis and scar contracture in the face and neck. Herein, we report the case of a 38-year-old woman (BMI 23.1 kg/m2, third-degree burns covering 40% of her body, an American Society of Anaesthesiologists physical status III) with an unusual case of airway constriction. This patient had a predictable difficult airway (mouth opening of 2 cm, bilateral nostril scar hyperplasia, Mallampatti score III, scarring of the head and neck, and severe tracheal stenosis). Tracheal stenosis measuring 5.5 mm in width as observed 8 cm below the glottis, and the bronchoscope could not pass through it. After two failed attempts at laryngeal mask insertion, we decided to instead insert a custom-made tracheal tube under the guidance of a fiberoptic bronchoscope. The operation was successful, and the patient was transferred to the intensive care unit (ICU).


Asunto(s)
Manejo de la Vía Aérea , Broncoscopía , Cicatriz , Contractura , Estenosis Traqueal , Humanos , Femenino , Adulto , Broncoscopía/métodos , Estenosis Traqueal/cirugía , Estenosis Traqueal/diagnóstico , Cicatriz/cirugía , Contractura/cirugía , Manejo de la Vía Aérea/métodos , Cuello/cirugía , Cara/cirugía , Intubación Intratraqueal/métodos , Quemaduras/complicaciones
2.
Eur J Cardiothorac Surg ; 66(3)2024 Sep 02.
Artículo en Inglés | MEDLINE | ID: mdl-39254596

RESUMEN

Surgical resection of the stenotic segment with end-to-end anastomosis is considered the gold standard in postintubation tracheal stenosis. However, outcomes of this concrete aetiology are not well described. With the aim to examine the extent, range and characteristics of the existing evidence, a scoping review was performed. Data sources included MEDLINE, Scopus, Ovid and the Cochrane databases. Inclusion criteria consisted of studies in adult patients with postintubation tracheal stenosis that reported characteristics, surgical management and outcomes. A total of 125 articles were identified, of which 10 were included in the final analysis. All studies were case reports or case series (level 4 evidence) grouping 110 patients, 75 males and 35 females. The age ranged from 15 to 71 years. Cotton-Myer stenosis grade was 1 [1 (0.9%)], 2 [25 (22.7%)], 3 [70 (63.6%)] and 4 [14 (12.7%)]. Stenosis location was in the tracheal upper-third in 108 (98.2%), in the middle-third in 1 (0.9%) and in the lower-third in 1 (0.9%). Stenosis length ranged from 1 to 5.6 cm. Follow-up ranged from 1 to 60 months (2 years for the most). Most frequent complications were transitory dysphagia in 13 (11.3%), granuloma formation in 8 (7.3%), dehiscence or air leak in 5 (4.5%) and wound infection in 4 (3.6%). Restenosis rate ranged from 2% to 25%. There was no perioperative mortality. Tracheal resection and primary anastomosis in postintubation tracheal stenosis appear to be safe and effective in the short and mid-terms; however, the very low level of evidence found prevents definitive conclusions.


Asunto(s)
Anastomosis Quirúrgica , Intubación Intratraqueal , Tráquea , Estenosis Traqueal , Humanos , Estenosis Traqueal/cirugía , Estenosis Traqueal/etiología , Intubación Intratraqueal/efectos adversos , Anastomosis Quirúrgica/efectos adversos , Tráquea/cirugía , Masculino , Femenino , Adulto , Persona de Mediana Edad , Adulto Joven , Anciano , Adolescente
3.
BMJ Case Rep ; 17(9)2024 Sep 24.
Artículo en Inglés | MEDLINE | ID: mdl-39317488

RESUMEN

Acquired supracarinal tracheal stenosis can be defined as postintubation tracheal stenosis of the lower third of the trachea that cannot be bypassed by standard or adjustable flange tracheostomy tubes. Owing to difficulty of access in the deep trachea, the transoral laser-assisted endoscopic surgical management of such stenoses is a challenge both for the surgeon and the anaesthetist alike. It requires good rapport and efficient cooperation between the teams to ensure appropriate oxygenation and carbon-dioxide washout while providing intermittent apnoeic phases to the surgeon for clear visualisation of the target area and use of Diode laser which is otherwise hazardous in an oxygen/nitrous oxide rich environment.From our tertiary care referral centre with strong work load for such pathologies, we report one such case of acquired tracheal stenosis successfully managed with transoral Diode laser-assisted surgery.


Asunto(s)
Estenosis Traqueal , Humanos , Estenosis Traqueal/cirugía , Láseres de Semiconductores/uso terapéutico , Intubación Intratraqueal/métodos , Terapia por Láser/métodos , Masculino , Cirugía Endoscópica por Orificios Naturales/métodos , Persona de Mediana Edad
4.
Laryngoscope ; 134(11): 4770-4773, 2024 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-39092623

RESUMEN

This article introduces a new endoscopic technique for anterior laryngotracheal reconstruction (LTR) using costal rib cartilage grafting in a 2-year-old patient with acquired Grade III subglottic stenosis. The procedure involves an endoscopic incision in the cricoid cartilage's anterior midline and successful outcomes were achieved without complications. The study emphasizes the benefits of this approach, such as reduced hospital stays, shorter operation time, and decreased scarring, but acknowledges the necessity for further human trials to validate its effectiveness in treating different grades of laryngeotracheal stenosis. Laryngoscope, 134:4770-4773, 2024.


Asunto(s)
Laringoestenosis , Procedimientos de Cirugía Plástica , Humanos , Laringoestenosis/cirugía , Preescolar , Procedimientos de Cirugía Plástica/métodos , Endoscopía/métodos , Masculino , Estenosis Traqueal/cirugía , Cartílago Costal/trasplante , Laringe/cirugía , Tráquea/cirugía , Cartílago Cricoides/cirugía , Resultado del Tratamiento
5.
Khirurgiia (Mosk) ; (8): 69-76, 2024.
Artículo en Ruso | MEDLINE | ID: mdl-39140946

RESUMEN

Endoscopic approach with recanalization and stenting is one of the methods for cicatricial tracheal stenosis. Major complications may occur if service life of stents is not observed. However, there are currently no clear timing for stenting. In world practice, there are no indications on lifelong stenting for cicatricial tracheal stenosis. Restenosis is more common after stent removal and requires repeated stenting or another treatment. In case of prolonged stenting, silicone stent should be periodically replaced with a similar one due to destruction of silicone rubber. As a rule, this maneuver is necessary after 1-3 years. Currently, there is no information about maximum allowable duration of stent without replacement and possible complications. Condition of trachea after prolonged stenting is also unknown. We present long-term (27 years) tracheal stenting with a silicone stent. Stent fragmentation and dislocation throughout this period led to respiratory failure and emergency removal. Tracheal lumen was satisfactory immediately after procedure. However, restenosis appeared after 1.5 months and required endoscopic dilation with discussion of appropriate treatment option. However, the patient refused tracheal resection with anastomosis and underwent repeated stenting with similar stent and favorable immediate result.


Asunto(s)
Siliconas , Stents , Estenosis Traqueal , Humanos , Estenosis Traqueal/cirugía , Estenosis Traqueal/etiología , Resultado del Tratamiento , Cicatriz/etiología , Cicatriz/cirugía , Tráquea/cirugía , Masculino , Femenino , Persona de Mediana Edad , Adulto
6.
BMC Pulm Med ; 24(1): 383, 2024 Aug 09.
Artículo en Inglés | MEDLINE | ID: mdl-39123192

RESUMEN

BACKGROUND: A straight silicone stent can be used to treat proximal benign tracheal stenosis in non-surgical candidates. However, stent migration is a common complication when placed at a particular location and can lead to major complications. This case series of laryngotracheal stenosis reports a fixation method for straight silicone stents in the subglottic trachea (Stage 3 of the McCaffrey classification). METHODS: The medical charts of these patients scheduled for straight silicone stent placement with suture fixation between 2014 and 2020 at the CHU UCL Namur Hospital (Belgium) were retrospectively reviewed. The procedure was performed using a rigid bronchoscope. Details of the procedure were obtained from medical records. RESULTS: This case series included six patients (males: 4, females: 2). The median patient age was 59 years. Two suture fixations were placed following previous silicone stent migration episodes, whereas the others were placed proactively to avoid this risk. All fixations were performed by the device Freka® Pexact II ENFIt®, originally developed for gastropexy in endoscopic gastrostomy. The sutures were subcutaneously buried. CONCLUSIONS: During the 6-month follow-up period, complications such as fixation issues and stent migration were reported despite the off-label use of the treatment. The straight silicone stent fixation technique used in this case series was simple and effective for securing the stent in upper benign tracheal stenosis.


Asunto(s)
Laringoestenosis , Stents , Estenosis Traqueal , Humanos , Femenino , Persona de Mediana Edad , Masculino , Estenosis Traqueal/cirugía , Laringoestenosis/cirugía , Estudios Retrospectivos , Anciano , Adulto , Técnicas de Sutura , Recurrencia , Siliconas , Broncoscopía
7.
J Otolaryngol Head Neck Surg ; 53: 19160216241266570, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39138869

RESUMEN

BACKGROUND: Pediatric laryngotracheal stenosis often requires open airway reconstruction. While these surgeries establish an airway for adequate ventilation, many patients develop subsequent dysphonia. Numerous studies have reported outcomes related to voice. OBJECTIVE: This study aims to evaluate dysphonia in pediatric patients following open airway reconstruction, focusing on acoustic parameters, perceptual voice quality, and voice-related quality of life. METHODS: A comprehensive search using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines across 6 databases identified articles involving pediatric patients who underwent open airway reconstruction and reported postoperative vocal acoustic parameters, perceptual voice quality, voice-related quality of life, or vocal mechanics. Articles were assessed for bias risk, and common outcomes were synthesized qualitatively and quantitatively using meta-analyses. RESULTS: Among 4089 articles, 21 were included, involving 497 pediatric patients. Laryngotracheoplasty was the most common procedure followed by cricotracheal resection. The Consensus Auditory-Perceptual Evaluation of Voice (CAPE-V) scale was frequently used to assess voice quality, with a mean score of 55.6 [95% confidence intervals (CIs): 47.9-63.3]. Voice-related quality of life was measured using the pediatric Voice Handicap Index (pVHI) and Pediatric Voice-Related Quality of Life Survey, with mean scores of 35.6 (95% CI: 21.4-49.7) and 83.7 (95% CI: 74.1-93.2), respectively. The fundamental frequency was 210.5 (95% CI: 174.6-246.3). Other common findings included supraglottic phonation, anterior commissure blunting, posterior glottic diastasis, and abnormal vocal cord mobility. CONCLUSION: Pediatric patients experiencing dysphonia after open airway reconstruction exhibited moderately decreased voice quality and reduced voice-related quality of life. However, there was inconsistency in study protocols and outcome measures used. Preserving voice quality during airway reconstruction is crucial to avoid negative impacts on quality of life.


Asunto(s)
Disfonía , Laringoestenosis , Calidad de Vida , Calidad de la Voz , Humanos , Disfonía/etiología , Laringoestenosis/cirugía , Niño , Estenosis Traqueal/cirugía , Complicaciones Posoperatorias , Procedimientos de Cirugía Plástica/métodos , Laringoplastia/métodos
8.
Vestn Otorinolaringol ; 89(3): 11-17, 2024.
Artículo en Ruso | MEDLINE | ID: mdl-39104267

RESUMEN

The article presents an analysis of the plastic reconstructive surgery effectiveness for patients with an extended tracheal defect using an allograft based on the dura mater (DM) at the final stage of surgical treatment of laryngeal and tracheal cicatricial stenosis. The study included 20 patients with cicatricial stenosis of the larynx and trachea, who were previously performed plastic reconstructive treatment with scar tissue excision in the lumen of the respiratory tract and restoration of the supporting frame of the larynx and trachea using allografts based on costal allocartilage. The age of the patients ranged from 21 to 54 years, the duration of the disease was from 1 to 5 years. After a standard clinical and laboratory examination, with a mandatory video endoscopic examination of the larynx and trachea, multislice computed tomography of the larynx and trachea, patients underwent plastic closure of the tracheal defect using DM. Dynamic outpatient monitoring was carried out once a week for 1 month, once a month for 3 months, control examination was done 6 months after surgical treatment. The results of the study demonstrated a full-fledged social and labor rehabilitation of all 20 patients after the final stage of surgical treatment using DM, the absence of rejection reaction and migration of allo-implantation material, the preserved lumen of the larynx and trachea with a rigid supporting skeleton and the absence of anterior tracheal wall floatation. The use of DM as an additional strengthening of the anterior tracheal wall for patients with deficiency of muscular aponeurotic tissues and more than 2 cm size tracheal defect is highly effective at the final stage of surgical treatment for plastic closure of the tracheal defect.


Asunto(s)
Cicatriz , Duramadre , Laringoestenosis , Procedimientos de Cirugía Plástica , Estenosis Traqueal , Humanos , Adulto , Masculino , Femenino , Laringoestenosis/cirugía , Laringoestenosis/etiología , Procedimientos de Cirugía Plástica/métodos , Persona de Mediana Edad , Estenosis Traqueal/cirugía , Estenosis Traqueal/etiología , Cicatriz/etiología , Cicatriz/cirugía , Duramadre/cirugía , Resultado del Tratamiento , Tráquea/cirugía , Laringe/cirugía
9.
Artículo en Inglés | MEDLINE | ID: mdl-39210535

RESUMEN

BACKGROUND: Self-expandable uncovered metallic stents (SEUMS) have been used in benign tracheobronchial stenosis. Stent complications may require risky removal due to SEUMS integration in the tracheobronchial wall. Our study aims to report techniques, including a novel one, and outcomes of SEUMS removal by rigid bronchoscopy. METHODS: We studied a case series of 7 patients from a tertiary medical center, who underwent SEUMS removal from 2017 to 2022. SEUMS removals were performed through rigid bronchoscopy. We used a new technique with bronchoscopic hook scissors to gradually dissect the stent from the airway wall. RESULTS: Nine SEUMS were removed from 7 patients. The mean duration of stenting was 7 years (5 to 12 y). Indications for stent removal included mostly recurrent pulmonary infections, obstructive granulation tissue, and stents' fractures. We used the usually described technique in the literature known as the "piecemeal fashion" without dissection in 4 SEUMS removals and a new dissection technique in 5 procedures. We reported one major intraoperative complication using the former technique in the form of tracheal tear with mediastinal breach, while we did not experience any major complications with the later one. One patient died 8 days after surgery from respiratory failure. CONCLUSION: Dissection and "piecemeal fashion techniques" can be used to remove SEUMS by rigid bronchoscopy even after long-term stenting. SEUMS removal is a very risky procedure and must be performed by a trained operator. Patients should be aware of possible severe complications.


Asunto(s)
Broncoscopía , Remoción de Dispositivos , Stents Metálicos Autoexpandibles , Estenosis Traqueal , Humanos , Remoción de Dispositivos/métodos , Broncoscopía/métodos , Masculino , Femenino , Persona de Mediana Edad , Anciano , Estenosis Traqueal/cirugía , Adulto , Stents/efectos adversos , Estudios Retrospectivos , Tráquea/cirugía
10.
Eur Arch Otorhinolaryngol ; 281(10): 5395-5410, 2024 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-38967672

RESUMEN

BACKGROUND: Benign laryngotracheal stenosis is widely managed with minimally invasive endoscopic interventions, such as laser incision or excision scar, and dilation. However, various endoscopic treatments are significantly associated with a high recurrence rate. Local auxiliary measures, including inhalation of steroids, injection of steroids, and local topical application of mitomycin C, have been studied in order to increase the success rate. PURPOSE: To compare the efficacy of endoscopic treatments with and without local adjuncts in patients with benign laryngotracheal stenosis, and analyze their clinical outcomes, recurrence, and complications. METHODS: In the meta-analysis, databases including PubMed, EMBASE, OVID, and Web of Science were searched for papers comparing the outcomes of adjunct therapy with non-adjunct therapy in patients with laryngotracheal stenosis. The duplicate publications, reviews, comments or letters, conference abstracts, and case reports were excluded. The random effect model was used for assessing the pooled risk estimates. RESULTS: Eight studies (1204 cases) referring to two prospective randomized controlled studies, two prospective cohort studies, and four retrospective cohort studies were ultimately included in the meta-analysis. Three delivery modes of adjuncts were identified, including intralesion steroid injection (n = 2), inhaled steroid (n = 2), and topical application of mitomycin C (n = 4). The decreased risk estimates of recurrence rate were detected in patients receiving endoscopic treatments with steroid injection or inhaled steroid, compared with endoscopic interventions alone (P < 0.05). Additionally, patients undergoing adjunct therapies had lower risk estimates of recurrence, compared to those receiving endoscopic procedures alone (P < 0.05), based on the subgroup of prospective cohort studies, subglottis, Mayer-Cotton scale of I-II degree, and stenosis length of < 3 cm. The high heterogeneity of the pooling risk estimates perhaps was due to factors of auxiliary drug, clinical characteristics of patients, and methodology. No discernible difference in the incidence of complication was identified. CONCLUSIONS: Local application of steroids to minimally invasive interventions appear to reduce the recurrence rate of laryngotracheal stenosis. Various adjuncts available, including steroids and mitomycin C, appear to be safe and associated with a low risk estimate of adjuncts-specific complication rate. High quality multi-center randomized controlled studies are needed, with sufficient periods for follow-up and subjective and objective outcome indicators, to properly evaluate the efficacy, safety, and cost-effectiveness of adjuvant drugs.


Asunto(s)
Laringoestenosis , Mitomicina , Estenosis Traqueal , Humanos , Laringoestenosis/cirugía , Mitomicina/administración & dosificación , Mitomicina/uso terapéutico , Estenosis Traqueal/cirugía , Endoscopía/métodos , Resultado del Tratamiento , Recurrencia , Procedimientos Quirúrgicos Mínimamente Invasivos/métodos , Laringoscopía/métodos , Administración por Inhalación
11.
Am J Otolaryngol ; 45(5): 104426, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39059164

RESUMEN

BACKGROUND: Long-segment, grade IV suprastomal tracheal stenosis is rare and difficult to treat (Carpenter et al., 2022 [1]). Patients with grade IV stenosis have significant quality of life impairments since they are tracheostomy dependent and aphonic. Open airway surgery is often needed to improve tracheal patency, restore the patient's voice, and progress towards decannulation (Abouyared et al., 2017 [2]). However, not all patients are candidates for upfront open surgery (Abouyared et al., 2017; Shamji, 2018 [2,3]). Therefore, it is important to develop and refine endoscopic interventions to improve quality of life for these patients. METHODS: We describe a step-by-step endoscopic approach to the recannulation of long-segment, grade IV suprastomal tracheal stenosis. Briefly, our approach utilizes dual (proximal & distal) visualization of the stenosis prior to passing a 25 gauge needle through the stenosis to identify the proper trajectory for recannulation. Then a 16 gauge needle is passed in the same manner, and a wire is placed through the needle and into the distal airway. Once the airway is recannulated, the initial pinpoint opening is gradually widened in Seldinger fashion over the wire with Savary dilators followed by balloon dilation. Finally, a suprastomal L-stent (modified Montgomery T-Tube) is placed to reduce the risk of restenosis (Edwards et al., 2023 [4]). CASE DISCUSSION: A 39-year-old woman with a past medical history significant for poorly controlled type I diabetes mellitus and polysubstance abuse presented with tracheostomy dependence and aphonia. She was diagnosed with a long-segment, grade IV suprastomal tracheal stenosis and initially underwent endoscopic recannulation. This intervention restored her voice and allowed for optimization of her medical conditions before open airway surgery. CONCLUSION: Most patients experience a significant improvement in their quality of life as their voice is typically restored following this procedure. Additionally, individuals who eventually require open airway surgery gain additional time for medical optimization. In our experience, this procedure represents a safe and effective means of extending the utility of traditional endoscopic airway interventions for the management of patients with grade IV stenosis.


Asunto(s)
Endoscopía , Estenosis Traqueal , Humanos , Estenosis Traqueal/cirugía , Endoscopía/métodos , Traqueostomía/métodos , Calidad de Vida , Tráquea/cirugía , Índice de Severidad de la Enfermedad , Resultado del Tratamiento , Femenino
12.
Artículo en Inglés | MEDLINE | ID: mdl-38839349

RESUMEN

T-tubes and airway stents are commonly used but have limited effectiveness and frequent complications. A 50-year-old male patient presented with severe tracheal stenosis, affecting an 8.7 cm length of the airway. We employed an innovative approach known as external suspension fixation of tracheal stent using robotic assistance. This method involves surgically attaching the stent to the exterior of the trachea to provide support and stabilize the softened or collapsed tracheal segments. We designed a C-shaped nickel-titanium alloy exterior stent and successfully fixed it using robotic assistance. This intervention effectively restored tracheal function and led to a favorable postoperative recovery. The technique does not affect tracheal membrane function or airway mucociliary clearance. It could potentially be considered as a new option for treating long-segment benign tracheal softening or collapse.


Asunto(s)
Níquel , Diseño de Prótesis , Procedimientos Quirúrgicos Robotizados , Stents , Titanio , Estenosis Traqueal , Humanos , Masculino , Persona de Mediana Edad , Estenosis Traqueal/cirugía , Estenosis Traqueal/diagnóstico por imagen , Estenosis Traqueal/etiología , Estenosis Traqueal/fisiopatología , Resultado del Tratamiento , Aleaciones
13.
Eur J Cardiothorac Surg ; 65(6)2024 Jun 03.
Artículo en Inglés | MEDLINE | ID: mdl-38830041

RESUMEN

OBJECTIVES: Children with congenital tracheal stenosis born in the developing world face a high risk of mortality due to limited access to proper treatment. Patients who required preoperative respiratory support were suspected to have poor survival after slide tracheoplasty; however, this was not clearly demonstrated in the previous studies. This study aims to investigate the impact of preoperative respiratory conditions on outcomes of slide tracheoplasty. METHODS: From 2016 to 2022, children who underwent slide tracheoplasty were retrospectively reviewed. Patients with respiratory distress requiring emergency operations (group A) were compared with patients in stable condition who were scheduled for surgery (group B). RESULTS: Perioperative results revealed that group A (n = 43) had a longer bypass time (P < 0.001), operation time (P = 0.01), postoperative ventilation time (P < 0.001) and length of intensive care unit stay (P = 0.00125) than group B (n = 60). The early mortality rate was 7.8%, and the actuarial 5-year survival rate was 85.3%. The cumulative incidence test revealed that group A was highly significant for overall mortality [sudistribution (SHR) 4.5; 95% confidence interval (CI) 1.23-16.4; P = 0.023]. Risk factors for overall mortality were prolonged postoperative ventilation time (hazard ratio 3.86; 95% CI 1.20-12.48; P = 0.024), bronchial stenosis (hazard ratio 5.77; 95% CI 1.72-19.31; P = 0.004), and preoperative tracheal mucositis (hazard ratio 5.67; 95% CI 1.51-21.31; P = 0.01). Four patients needed reintervention during a follow-up of 28.4 months (interquartile range 15.3-47.3). CONCLUSIONS: Preoperative respiratory distress negatively affected the outcomes of patients who required slide tracheoplasty. Therefore, early detection of congenital tracheal stenosis and aggressive slide tracheoplasty are crucial and obligatory to enhance long-term survival in this lethal congenital airway disease.


Asunto(s)
Tráquea , Estenosis Traqueal , Humanos , Estudios Retrospectivos , Femenino , Masculino , Estenosis Traqueal/cirugía , Estenosis Traqueal/congénito , Estenosis Traqueal/mortalidad , Tráquea/cirugía , Tráquea/anomalías , Recién Nacido , Lactante , Resultado del Tratamiento , Procedimientos de Cirugía Plástica/métodos , Factores de Riesgo , Preescolar
14.
Int J Pediatr Otorhinolaryngol ; 182: 111993, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-38885545

RESUMEN

INTRODUCTION: Slide tracheoplasty has become the gold standard surgery for congenital tracheal stenosis (CTS). This condition is rare and the surgery can be challenging and is performed by experienced surgeons in tertiary centers. A few reports involving relatively small cohorts have been published. The aim of this review is to evaluate the post-operative mortality and morbidity of pediatric slide tracheoplasty for CTS. METHODS: A systematic literature review was performed according to PRISMA guidelines. The Medline and EMBASE databases were screened using a search strategy defined in collaboration with a librarian. We included articles reporting the post-operative mortality rate of slide tracheoplasties for treatment of CTS in children, when at least 10 patients were included. RESULTS: A total of 932 articles were reviewed, and 15 studies were eligible with a total of 845 patients. The overall post-operative mortality rate was 9.3 %, and most deaths were airway related. The open revision surgery rate after surgery was 2.8 % and the endoscopic revision rate was 27.6 %. DISCUSSION: This study highlights key factors to consider before the surgery and helps anticipate post-operative follow-up considerations for children with CTS. Several factors were identified as predictors of mortality including young age, weight at the time of surgery and association with lung hypoplasia or aplasia. CONCLUSION: Although slide tracheoplasty has gained popularity in recent years due to better outcomes, it remains a major surgery with mortality risk and the need for multidisciplinary management.


Asunto(s)
Procedimientos de Cirugía Plástica , Tráquea , Estenosis Traqueal , Humanos , Estenosis Traqueal/cirugía , Estenosis Traqueal/congénito , Procedimientos de Cirugía Plástica/métodos , Tráquea/cirugía , Tráquea/anomalías , Resultado del Tratamiento , Complicaciones Posoperatorias/epidemiología , Niño , Reoperación/estadística & datos numéricos
15.
Swiss Med Wkly ; 154: 3363, 2024 Jun 17.
Artículo en Inglés | MEDLINE | ID: mdl-38885613

RESUMEN

BACKGROUND: Benign tracheal stenosis is relatively rare but remains a significant chronic disease due to its drastic symptoms including dyspnoea and inspiratory stridor, and consequent negative effect on quality of life. Traditionally, the surgical approach by resection of the stenotic tracheal segment has been the therapy of choice. However, endoscopic techniques have arisen and may offer a safe and less invasive alternative. OBJECTIVES: The aim of the retrospective study was to evaluate procedure-related safety and outcome of endoscopic treatment of benign tracheal stenosis at a single centre. METHODS: The study included all patients at our institution who between 2013 and 2022 had received endoscopic treatment of benign tracheal stenosis by rigid tracheoscopy, radial incision by electric papillotomy needle and dilation (endoscopic tracheoplasty) followed by triamcinolone acetonide as a local submucosal injection and additionally, from 2020, budesonide inhalation. RESULTS: A total of 22 patients were treated in a total of 38 interventions, each resulting in immediate improvement of symptoms. There were no peri-interventional complications or mortality. Of the 38 interventions, 11 received no triamcinolone acetonide administration, resulting in a 54.5% recurrence rate after an average of 21.1 (±18.0) months, while 27 had local triamcinolone acetonide, with a 37% recurrence rate. Since 2020, we additionally initiated post-interventional budesonide inhalation as recurrence prophylaxis for newly admitted patients and patients with recurrences(n = 8), of whom only one (12.5%) has to date experienced a recurrence. CONCLUSION: Our results indicate that endoscopic tracheoplasty offers a safe and successful, minimally invasive alternative to open surgery for patients with benign tracheal stenosis. We recommend local administration of triamcinolone into the mucosa as an additional treatment to decrease the risk of recurrence. However, given the uncontrolled study design and low sample size, safety and effectiveness cannot be conclusively demonstrated. Nonetheless, our findings suggest promising avenues for further investigation. Further studies on the additional benefit of inhaled corticosteroids are warranted.


Asunto(s)
Estenosis Traqueal , Humanos , Estenosis Traqueal/cirugía , Femenino , Masculino , Estudios Retrospectivos , Persona de Mediana Edad , Endoscopía/métodos , Adulto , Triamcinolona Acetonida/administración & dosificación , Triamcinolona Acetonida/uso terapéutico , Resultado del Tratamiento , Dilatación/métodos , Recurrencia , Anciano , Budesonida/administración & dosificación , Budesonida/uso terapéutico , Calidad de Vida , Glucocorticoides/administración & dosificación , Glucocorticoides/uso terapéutico
16.
BMJ Case Rep ; 17(5)2024 May 28.
Artículo en Inglés | MEDLINE | ID: mdl-38806399

RESUMEN

Increasing use of tracheal expandable metallic hybrid stents will lead to common encounters with these devices in emergency airway management. The presence of these stents qualifies any patient as a challenge when an emergency tracheostomy is needed. We report an unorthodox technique of tracheostomy with concomitant removal of tracheal stent, without any major complications. Although the combined approach with bronchoscopy and tracheostomy has been reported in similar cases, we present a safe procedure when rigid bronchoscopy is not available.


Asunto(s)
Broncoscopía , Remoción de Dispositivos , Traqueostomía , Humanos , Traqueostomía/efectos adversos , Traqueostomía/instrumentación , Traqueostomía/métodos , Remoción de Dispositivos/métodos , Broncoscopía/métodos , Stents/efectos adversos , Tráquea/cirugía , Masculino , Estenosis Traqueal/cirugía , Estenosis Traqueal/terapia , Estenosis Traqueal/etiología , Femenino
17.
BMC Pulm Med ; 24(1): 238, 2024 May 15.
Artículo en Inglés | MEDLINE | ID: mdl-38750487

RESUMEN

BACKGROUND: Biodegradable (BD) stents made from polydioxanone have been used only in human airways. These stents combine the advantages of classical tracheal stents, and fewer side effects are expected due to their biocompatibility and their time-limited presence in airways. However, new clinical consequences have arisen. Here, the authors share their experiences with BD stents for tracheal indications, focusing on their safety and efficacy. METHODS: This was a retrospective review of a collected database of adult patients who underwent implantation of biodegradable tracheal stents between September 2013 and December 2022 at the Department of Respiratory Medicine of the 1st Faculty of Medicine in Prague and Thomayer University Hospital. The indications included functionally significant nonmalignant tracheal stenosis and tracheomalacia. Self-expandable, biodegradable, polydioxanone tracheal stents manufactured by ELLA-CS Ltd. (Hradec Kralove, Czech Republic) were implanted during rigid bronchoscopy under general anaesthesia. All patients were followed up in the department and were provided with the necessary care. The main efficacy and safety parameters and relationships were analysed using descriptive statistics and Fisher´s exact, Wilcoxon and Kruskal‒Wallis tests. RESULTS: A total of 65 stents were implanted in 47 adult patients. During the first two months after implantation, when adequate function was expected, the stent was found to be effective in 26 out of 39 patients who completed this period (66.7%). The clinical effectiveness reached 89.7%, as early restenoses were mostly mild and necessitated treatment in only 4 patients. The frequencies of significant mucostasis, migration and granulation tissue growth were 2.6%, 7.5% and 23.1%, respectively, during this period. Thirty-four participants completed the half-year follow-up period after the first or second stent insertion, and some were followed up beyond this period. Poor control of symptoms, the development of restenosis and the need for interventions were characteristic of this period as the stents degraded. Twenty-two patients who experienced remodelling or stabilization of the tracheal lumen achieved a stent-free state. Seven patients underwent subsequent surgical treatment. CONCLUSIONS: BD stents are safe and provide adequate tracheal support until they begin to degrade. The use of BD stents necessitates close monitoring of patients and accurate treatment of possible restenosis. TRIAL REGISTRATION: Based on project NT14146 - Biodegradable stents in the management of the large airways (2013-2015, MZ0/NT), registered on May 1, 2013, in the Research and Development and Innovation Information System of the Czech Republic and at ClinicalTrials.gov (reg. no. NCT02620319, December 2, 2015).


Asunto(s)
Implantes Absorbibles , Broncoscopía , Stents , Estenosis Traqueal , Humanos , Persona de Mediana Edad , Masculino , Femenino , Estudios Retrospectivos , Adulto , Estenosis Traqueal/cirugía , Anciano , Polidioxanona , Traqueomalacia/cirugía , República Checa , Resultado del Tratamiento , Tráquea/cirugía , Diseño de Prótesis , Adulto Joven
18.
Einstein (Sao Paulo) ; 22: eRC0659, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38695416

RESUMEN

A female newborn presented with respiratory distress at birth and was diagnosed with congenital tracheal stenosis. The stenosis was positioned at the distal trachea and compromised the carina and the right and left bronchi. She underwent surgical treatment using circulatory life support with veno-arterial peripheral extracorporeal membrane oxygenation, and the airway was reconstructed using the slide tracheoplasty technique to build a neocarina. The patient had an excellent postoperative course, was successfully weaned from extracorporeal membrane oxygenation and invasive ventilation, and was discharged.


Asunto(s)
Bronquios , Oxigenación por Membrana Extracorpórea , Procedimientos de Cirugía Plástica , Tráquea , Estenosis Traqueal , Humanos , Femenino , Estenosis Traqueal/cirugía , Estenosis Traqueal/congénito , Estenosis Traqueal/diagnóstico por imagen , Recién Nacido , Tráquea/cirugía , Tráquea/anomalías , Tráquea/diagnóstico por imagen , Oxigenación por Membrana Extracorpórea/métodos , Bronquios/cirugía , Bronquios/anomalías , Bronquios/diagnóstico por imagen , Procedimientos de Cirugía Plástica/métodos , Resultado del Tratamiento
19.
Am J Otolaryngol ; 45(4): 104318, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38678801

RESUMEN

OBJECTIVES: To demonstrate varying degrees of immediate postoperative figure of 8 deformity following three different methods of tracheal suturing. STUDY DESIGN: Comparative ex-vivo study. METHODS: A fresh, unfixed rabbit trachea was harvested and bisected at its midpoint. The posterior membranous trachea was excised from both segments to mimic the anatomy of complete tracheal rings following longitudinal release. A slide tracheoplasty was performed on the same tracheal segments as an internal control, using three different methods of closure: simple running, running horizontal mattress, and a modified baseball stitch. Endoscopic and external photographs were taken immediately following repair to document the effect of closure technique on external and endoluminal anatomy. RESULTS: A simple running closure, in which traveling occurs between needle passes, showed the greatest degree of postoperative figure of 8 deformity. A running horizontal mattress suture closure showed less deformity and a modified running closure, in which traveling occurs within needle passes, showed the least deformity. CONCLUSIONS: Our study suggests that a minor modification of standard running closure techniques may help limit the common figure-of-8 deformity often noted following slide tracheoplasty. LAY SUMMARY: Figure of-8 deformity is a problem that can occur when repairing a narrow trachea referred to as tracheal stenosis. This deformity may be prevented using particular suture techniques which may decrease the likelihood that the trachea becomes blocked again following repair.


Asunto(s)
Técnicas de Sutura , Tráquea , Tráquea/cirugía , Animales , Conejos , Estenosis Traqueal/cirugía , Complicaciones Posoperatorias/prevención & control , Procedimientos de Cirugía Plástica/métodos
20.
Eur Arch Otorhinolaryngol ; 281(6): 3083-3093, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38564008

RESUMEN

PURPOSE: To examine the factors that affect graft healing after laryngotracheal reconstruction (LTR). METHODS: We conducted a retrospective chart review at King Abdulaziz University Hospital, Riyadh, Saudi Arabia, between January-2008 and October-2023. We included all patients who underwent LTR and required anterior and/or posterior graft placement, while those who underwent procedures without graft placement and those with incomplete information were excluded. RESULTS: Forty-nine patients were analyzed. Most patients were pediatric (65.3%), male (65.3%), had no coexisting comorbidities (55.1%), and harbored grade 3-4 stenosis (59.2%). Thirty patients (61.2%) underwent open surgery. Various graft complications occurred including infection (n = 1, 2%), dehiscence (n = 3, 6.1%), scar (n = 6, 12.2%), and granulation (n = 29, 59.2%). Only 15 patients (30.65%) achieved the composite status of "healthy" graft. Among 43 patients who had postoperative cultures, positive results for Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus were observed in 10 and four patients, respectively. Open surgery and double-stage procedure were significantly associated with higher rates of granulation tissue formation. Pediatric-age group had significantly higher rate of complete epithelization compared to adult-age group. A significantly greater proportion of patients who had unhealthy grafts had open surgery. The rate of double-stage LTR was significantly higher in unhealthy grafts compared to healthy grafts. Prolonged stent duration was linked to various graft-related complications. Multivariate logistic regression analyses showed no statistically significant correlations between various factors and postoperative graft-related complications. CONCLUSION: Open surgery, double-stage procedure, pediatric age group, and stent duration were not significant risk factors associated with postoperative graft-related complications during LTR in multivariate analysis.


Asunto(s)
Laringoestenosis , Procedimientos de Cirugía Plástica , Estenosis Traqueal , Humanos , Masculino , Femenino , Estudios Retrospectivos , Niño , Adolescente , Laringoestenosis/cirugía , Procedimientos de Cirugía Plástica/métodos , Estenosis Traqueal/cirugía , Adulto , Preescolar , Cicatrización de Heridas , Complicaciones Posoperatorias/epidemiología , Persona de Mediana Edad , Adulto Joven , Arabia Saudita/epidemiología , Tráquea/cirugía , Factores de Riesgo
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