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Rev. méd. Chile ; 141(11): 1427-1433, nov. 2013. tab
Artigo em Espanhol | LILACS | ID: lil-704570

RESUMO

American Trypanosomiasis or Chagas Disease is a major public health problem, endemic in the American continent since prehistoric times. Its natural course is towardschronicity in the immunocompetent host, often leading to severe cardiopathy or bowelinvolvement. Pharmacologic therapy is restricted to two drugs and only one of themis currently available in Chile. Both have poor effectiveness in the chronic stages ofthe disease and cause frequent adverse reactions. Many physicians avoid their use,despite published evidences about the usefulness. We herein report the experienceof our Center in the treatment of Chronic Chagas Disease in adults using the drugnifurtimox, emphasizing its degree of acceptability and its secondary effects.


Assuntos
Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Doença de Chagas/tratamento farmacológico , Nifurtimox/uso terapêutico , Tripanossomicidas/uso terapêutico , Doença de Chagas/epidemiologia , Chile/epidemiologia , Doença Crônica , Adesão à Medicação , Nifurtimox/efeitos adversos , Tripanossomicidas/efeitos adversos
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