A Case of Wilms Tumor in a Primary Adrenal Mature Teratoma.

We report the first known case of an adrenal teratoma containing a Wilms tumor component, in a 12-month-old girl with Trisomy 21. Despite adrenal teratomas being relatively uncommon, this particular instance raises interesting questions regarding the tumor origin, given the coexistence of both a teratoma and a Wilms tumor. Two main theories of development have been hypothesized, one of which suggests that the Wilms tumor may develop from a primary teratoma and the other proposing that the teratoma could originate from a primary Wilms tumor. Our case study leans toward the former, as the majority of the tumor displayed characteristics of a typical mature teratoma, with the Wilms component discovered as an incidental finding. Successful surgical intervention led to the gross total resection of the tumor. Twelve months post-resection, the patient remains free of recurrence. This report contributes to our understanding of these rare tumor types and underlines the importance of identifying the primary tumor to ensure appropriate management and treatment.

A Sizable Aortic Root Paravalvular Mycotic Pseudoaneurysm.

Mycotic aneurysm is an established condition first identified in 1885 by Sir William Osler. It is linked to malignant endocarditis. With prevalence of 0.7-2.6% of all cases of aortic aneurysms, it is associated with a significant rate of mortality and morbidity. Physicians should be highly cautious, as diagnosis and effective treatment for this condition are difficult. The following is a case report of a 13-year-old pediatric patient diagnosed with mycotic aneurysm. Before an adequate treatment plan could be developed and implemented, patient's status worsened swiftly and was ultimately terminal. This case is the sole instance of this condition evidenced in the last ten years in Saudi Arabia.

The impact of maternal iron deficiency and iron deficiency anemia on child's health.

Iron deficiency anemia is extremely common, particularly in the developing world, reaching a state of global epidemic. Iron deficiency during pregnancy is one of the leading causes of anemia in infants and young children. Many women go through the entire pregnancy without attaining the minimum required intake of iron. This review aims to determine the impact of maternal iron deficiency and iron deficiency anemia on infants and young children. Extensive literature review revealed that iron deficiency is a global nutritional problem affecting up to 52% of pregnant women. Many of these women are symptomatic. Lack of proper weight gain during pregnancy is an important predictor of iron deficiency.

Metabolic syndrome in the survivors of childhood acute lymphoblastic leukaemia.

Metabolic syndrome is a common complication encountered in children surviving acute lymphoblastic leukaemia (ALL). Affected patients develop obesity, insulin resistance, hypertension, and hyperlipidemia. Metabolic syndrome is a consequence of multiple factors, particularly hormonal imbalance induced by various ALL treatments. This review aims to evaluate the risk factors and mechanisms leading to the development of metabolic syndrome. Further research is needed to improve our understanding of the mechanisms leading to insulin resistance and the associated endothelial and adipose tissue dysfunction. Future studies should also examine other possible contributing factors, such as environmental and genetic factors. Understanding these factors will help in guiding modifications of the current ALL treatment protocols in order to prevent the development of this syndrome and hence improve the quality of life of ALL survivors. Until this is achieved, clinicians should continue to identify patients at risk early and use a therapeutic approach that combines dietary restrictions and enhanced physical activity.

The influence of fish oil on neurological development and function.

Fish oil originates from fish tissue rich in omega-3 fatty acids. These include eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). Healthy individuals are advised to consume foods rich in fish oil at least twice a week. However, such intake varies depending on cultural or personal preference, and socio-economic status. Many families and patients with chronic neurological conditions consume supplements containing omega-3 fatty acids. We are frequently requested to give advice and recommendations on using such agents to help improve neurological developmental and cognitive functions. The objective of this review is to discuss the available literature supporting the role of fish oils on brain development and function. There is a growing body of literature suggesting a potential benefit of long chain polyunsaturated fatty acids; however it is still unclear if there are response variations according to the developmental stage, age, and dose. L'influence de l'huile de poisson sur le développement et la fonction neurologique. L'huile de poisson provient de tissus de poisson riches en acides gras oméga-3, l'acide eicosapentaéno&IUque (EPA) et l'acide docosahexaénoïque (DHA). On conseille aux individus en bonne santé de consommer des aliments riches en huiles de poisson au moins deux fois par semaine. Cependant, leur consommation varie selon les préférences culturelles ou personnelles ainsi que selon le statut socio-économique. Plusieurs familles et plusieurs patients atteints de maladies neurologiques chroniques consomment des suppléments contenant des acides gras oméga-3. On nous demande souvent des conseils et des recommandations sur l'utilisation de ces agents pour aider à améliorer le développement neurologique et les fonctions cognitives. L'objectif de cette revue est de discuter de la littérature disponible en faveur du rôle des huiles de poisson dans le développement et le fonctionnement du cerveau. Il existe une documentation de plus en plus importante qui suggère que les acides gras polyinsaturés à longue chaîne pourraient etre bénéfiques. Cependant, on ne sait pas si la réponse peut varier selon le stade du développement, l'âge et la dose.