[Clinical aspects of the radioimmunoassay of carcinoembryonic antigen levels in breast cancer]. / Nekotorye klinicheskie aspekty radioimmunologicheskogo issledovaniia urovnia rakovoémbrional'nogo antigena u bol'nykh rakom molochnoi zhelezy.

The paper is concerned with the results of radioimmunoassay of the CEA level in the blood serum of 235 patients with breast cancer, 48 patients with fibrous-cystic mastopathies and 51 healthy women. In 100 patients with generalized breast cancer repeated examination of the CEA level was done during drug treatment. The authors showed a possibility to use in practice the results of radioimmunoassay of CEA in patients with breast cancer in early stages as a prognostic test as well as an additional criterion in the evaluation of drug therapeutic efficacy in patients with generalized breast cancer.

[Thyroid activity in patients with thyroid neoplasms]. / Osobennosti tireoidnoi aktivnosti u bol'nykh opukholiami shchitovidnoi zhelezy.

Levels of thyroid hormones and thyrotropin in 58 cases of adenoma and 86 cases of cancer of the thyroid gland were assayed radioimmunologically. Secretory function of the thyroid gland was inhibited in cancer patients and increased in adenoma group. Due to feedback, peripheral blood--thyrotropin levels were lowered in adenoma patients and raised in the cancer group. The hormonal disturbances were not identical in males and females; they were more pronounced in patients with disseminated tumor aged 46-55. The latter finding points to a decline in thyroid function with aging.