RESUMO
We evaluated the accuracy of patient-collected skin lesions, oropharyngeal, and rectal swabs among 50 individuals enrolled in a study of mpox viral dynamics. We found that the performance of self-collected samples was similar to that of physician-collected samples, suggesting that self-sampling is a reliable strategy for diagnosing mpox.
Assuntos
Mpox , Humanos , Feminino , Orofaringe , Esfregaço VaginalAssuntos
Doença de Crohn , Hidradenite Supurativa , Anticorpos Monoclonais Humanizados , Doença de Crohn/complicações , Doença de Crohn/diagnóstico , Doença de Crohn/tratamento farmacológico , Hidradenite Supurativa/diagnóstico , Hidradenite Supurativa/tratamento farmacológico , Humanos , Talidomida/análogos & derivados , Talidomida/uso terapêuticoRESUMO
We present the case of a 16-year-old boy with Peutz-Jeghers disease with successful treatment of oral lentiginosis with one session of picosecond 755-nm alexandrite laser. To date, only in one other article picosecond laser is used for lentiginosis in Peutz-Jeghers disease. Other therapeutical options include Q-switched 755-nm alexandrite, 1064-nm Nd:YAG, 532-nm KTP-laser, ruby and intense pulsed light, which generally require more sessions, are less pigment-selective and have overall worse results than picosecond laser treatment.
Assuntos
Terapia a Laser , Lasers de Estado Sólido , Lentigo , Síndrome de Peutz-Jeghers , Adolescente , Berílio , Humanos , Terapia a Laser/métodos , Lasers de Estado Sólido/uso terapêutico , Lentigo/etiologia , Lentigo/radioterapia , Lentigo/cirurgia , Masculino , Síndrome de Peutz-Jeghers/complicações , Síndrome de Peutz-Jeghers/radioterapia , Síndrome de Peutz-Jeghers/cirurgia , Resultado do TratamentoAssuntos
Brentuximab Vedotin , Imunoconjugados , Linfoma Anaplásico de Células Grandes , Antineoplásicos Imunológicos/uso terapêutico , Brentuximab Vedotin/uso terapêutico , Humanos , Imunoconjugados/uso terapêutico , Antígeno Ki-1 , Linfoma Anaplásico de Células Grandes/diagnóstico , Linfoma Anaplásico de Células Grandes/tratamento farmacológico , Linfoma Anaplásico de Células Grandes/patologiaRESUMO
A 4-year-old girl presented with congenital patches of scalp alopecia, which on physical examination, was consistent with blaschkolinear alopecic patches with mild epidermal atrophy. Similar atrophic hypopigmented patches were seen on the trunk and proximal extremities. With the clinical suspicion of Conradi-Hünermann-Happle syndrome, genetic testing was performed and revealed a mutation in the EBP gene. Despite characteristic cutaneous findings, no skeletal, ocular, or other anomalies were found on further evaluation.