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1.
Clin Exp Dermatol ; 2024 Sep 19.
Artigo em Inglês | MEDLINE | ID: mdl-39298635

RESUMO

INTRODUCTION: Dermoscopy is a valuable tool in the diagnosis of various skin conditions. Dermoscopy increases the sensitivity and specificity for skin cancer diagnosis, as well as infectious, inflammatory, and hair diseases. However, mastering dermoscopy intricacies poses challenges. In this context, innovative educational methods are sought, including game-based learning (GBL) strategies. OBJECTIVE: To describe current perceptions, knowledge and usage of GBL strategies in dermoscopy education; and identify strengths and challenges to enhance their utilization. METHODS: This was a cross-sectional study conducted by the International Dermoscopy Society (IDS). A web-based survey with 25-questions was distributed among the IDS members between October 2022 and April 2023. Responses were collected and analyzed using SPSS Statistics 26. RESULTS: A total of 801 responses were received. Of these, 46.6% responders were unfamiliar with gamification and serious games. Among those acquainted, 56.3% reported using GBL strategies for education. Younger participants were more likely to use GBL strategies (p = 0.015). Participants familiar with GBL believed it enhances medical education (78.5%) but not as a sole replacement for traditional methods (96%). For dermoscopy education, 22.2% had used GBL strategies, with Kahoot (35.5%) and You Dermoscopy (24.1%) being the most commonly used. Respondents found gaming strategies to be fun (95%), motivating (91%), and valuable for e-learning (94%). CONCLUSION: Results from this survey demonstrate favorable perception towards GBL strategies in dermatology education, including dermoscopy. While there are ongoing challenges in validation, GBL strategies are promising and valuable tools that can aid the learning and teaching experience. Addressing implementation barriers and validating existing games could optimize GBL's impact on dermatology education.

2.
Cancers (Basel) ; 16(17)2024 Sep 04.
Artigo em Inglês | MEDLINE | ID: mdl-39272935

RESUMO

Incorporation of dermoscopy and artificial intelligence (AI) is improving healthcare professionals' ability to diagnose melanoma earlier, but these algorithms often suffer from a "black box" issue, where decision-making processes are not transparent, limiting their utility for training healthcare providers. To address this, an automated approach for generating melanoma imaging biomarker cues (IBCs), which mimics the screening cues used by expert dermoscopists, was developed. This study created a one-minute learning environment where dermatologists adopted a sensory cue integration algorithm to combine a single IBC with a risk score built on many IBCs, then immediately tested their performance in differentiating melanoma from benign nevi. Ten participants evaluated 78 dermoscopic images, comprised of 39 melanomas and 39 nevi, first without IBCs and then with IBCs. Participants classified each image as melanoma or nevus in both experimental conditions, enabling direct comparative analysis through paired data. With IBCs, average sensitivity improved significantly from 73.69% to 81.57% (p = 0.0051), and the average specificity improved from 60.50% to 67.25% (p = 0.059) for the diagnosis of melanoma. The index of discriminability (d') increased significantly by 0.47 (p = 0.002). Therefore, the incorporation of IBCs can significantly improve physicians' sensitivity in melanoma diagnosis. While more research is needed to validate this approach across other healthcare providers, its use may positively impact melanoma screening practices.

4.
Am J Dermatopathol ; 46(4): 218-222, 2024 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-38457683

RESUMO

ABSTRACT: Follicular dendritic cell sarcoma is a rare intermediate-grade malignancy characterized by a proliferation of ovoid to spindle-shaped cells with morphologic and immunophenotypic features similar to normal follicular dendritic cells. It may develop in lymph nodes or extranodal sites. Its presentation in extranodal tissues is a diagnostic challenge. It requires a high index of suspicion because follicular dendritic cell markers are not included in the routine immunohistochemical panels used for differential diagnosis. In an extensive review of the English literature, we found 3 cases of follicular dendritic cell sarcoma developing on the skin. We report a case of a primary cutaneous follicular dendritic cell sarcoma in a 28-year-old man, which presented as a 6-mm skin-colored nodule on the right forearm. We describe the morphologic and immunohistochemical features and a review of the literature.


Assuntos
Sarcoma de Células Dendríticas Foliculares , Masculino , Humanos , Adulto , Sarcoma de Células Dendríticas Foliculares/diagnóstico , Sarcoma de Células Dendríticas Foliculares/patologia , Pele/patologia , Diagnóstico Diferencial , Linfonodos/patologia , Imunofenotipagem
6.
J Drugs Dermatol ; 22(12): 1153-1159, 2023 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-38051841

RESUMO

BACKGROUND: The International Dermatology Outcome Measures (IDEOM) is a non-profit organization dedicated to the advancement of evidence-based, consensus-driven outcome measures in dermatological diseases. Researchers and stakeholders from various backgrounds collaborate to develop these objective benchmark metrics to further advance treatment and management of dermatological conditions. SUMMARY: The 2022 IDEOM Annual Meeting was held on June 17-18, 2022. Leaders and stakeholders from the hidradenitis suppurativa, acne, vitiligo, actinic keratosis, alopecia areata, itch, cutaneous lymphoma, and psoriatic disease workgroups discussed the progress of their respective outcome-measures research. This report summarizes each workgroup's updates from 2022 and their next steps as established during the 2022 IDEOM Annual Meeting. J Drugs Dermatol. 2023;22(12):1153-1159 doi:10.36849/JDD.7615.


Assuntos
Alopecia em Áreas , Dermatologia , Psoríase , Neoplasias Cutâneas , Humanos , Avaliação de Resultados em Cuidados de Saúde , Psoríase/tratamento farmacológico
7.
Dermatol Pract Concept ; 13(4)2023 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-37992344

RESUMO

The incidence of melanoma has been dramatically increasing over the last decades. Melanoma is considered to have a high metastatic potential and it can progress via lymphatic vessels or through hematogenous metastasis. Different patterns of recurrence have been described, namely, local, satellite, and in transit metastasis (LCIT), lymphatic metastasis, and systemic metastasis. With a more advanced melanoma stage at diagnosis, there is a higher risk for systemic metastasis in comparison to LCIT; in contrast, early-stage melanoma tends to recur more frequently as LCIT and less commonly as systematic metastasis. The aim of this review was to summarize the patterns of recurrence of cuta-neous melanoma, giving the clinician a practical summary for diagnosis, prognosis, and surveillance. There is a knowledge gap of the common patterns of recurrence that needs to be addressed to better identify patients at high risk of disease recurrence and personalize surveillance strategies as well as patient counseling.

9.
J Rheumatol ; 50(Suppl 2): 11-13, 2023 11.
Artigo em Inglês | MEDLINE | ID: mdl-37419622

RESUMO

Interleukin (IL)-17 and IL-23 inhibitors are both approved for the treatment of moderate-to-severe plaque psoriasis (PsO), as well as psoriatic arthritis (PsA). In the absence of head-to-head studies, it is not clear which agent is better suited to treat patients with moderate-to-severe PsO and mild PsA. During the 2022 Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) conference, Dr. April Armstrong and Dr. Joseph Merola debated which of these 2 biologic classes should be used in this patient population. Armstrong argued in favor of IL-17 inhibition, whereas Merola presented reasons for IL-23 inhibition. An overview of their main arguments is described in this manuscript.


Assuntos
Artrite Psoriásica , Dermatologia , Psoríase , Humanos , Artrite Psoriásica/tratamento farmacológico , Inibidores de Interleucina , Interleucina-17 , Psoríase/tratamento farmacológico , Interleucina-23
11.
Rev. chil. dermatol ; 36(4): 186-193, 2020. tab, ilus
Artigo em Espanhol | LILACS | ID: biblio-1400567

RESUMO

Las fotodermatosis son un conjunto de patologías cutáneas originadas o agravadas por exposición a radiación ya sea solar o artificial. Se clasifican en cuatro categorías: 1. Idiopáticas o mediadas inmunológicamente 2. Dermatosis fotoagravadas, 3. Fotosensibilidad inducida por agentes y 4. Trastornos por reparación defectuosa del ADN. La fotosensibilidad inducida por agentes consiste en reacciones secundarias a la exposición de ciertos químicos, llamados fotosensibilizadores y a distintos tipos de radiación lumínica. Los fotosensibilizadores pueden ser de origen endógeno o exógeno, aquellos exógenos provienen desde el ambiente, fármacos u otros productos (tanto sistémicos como tópicos), los cuales sufren modificaciones estructurales al entrar en contacto con radiación, provocando como consecuencia, distintas manifestaciones cutáneas. En este artículo se revisarán principalmente las reacciones fototóxicas y fotoalérgicas (ambas, reacciones de fotosensibilidad inducidas por agentes exógenos) indagando en sus diferencias y el enfrentamiento clínico de cada una. También, se revisarán los exámenes que permiten estudiar los distintos diagnósticos diferenciales, especialmente el test de fotoparches, el cual está cobrando cada vez más importancia en la práctica clínica.


Photodermatoses are a group of skin diseases induced or aggravated by exposure to radiation, whether solar or artificial. They are classified into four general categories: 1. Idiopathic or immunologically mediated photodermatoses 2. Photoexacerbated dermatoses 3. Agent induced photosensitivity 4. DNA repair defects Photosensitivity induced by agents are secondary reactions to the exposure to some chemicals, called photosensitizers, and to different types of light radiation. Photosensitizers can be classified as exogenous or endogenous. Exogenous agents come from the environment, drugs or other products (both systemic and topical), which undergo structural changes when they come into contact with radiation, causing different skin manifestations as consequence. Differences between phototoxic and photoallergic reactions (both photosensitivity reactions induced by exogenous agents), the clinical approach of each one of them, and available tests that are used to make a diagnosis, especially, photo patch test will be reviewed in this article


Assuntos
Humanos , Masculino , Feminino , Testes do Emplastro/métodos , Dermatite Fotoalérgica/diagnóstico , Dermatite Fotoalérgica/etiologia , Fármacos Fotossensibilizantes/efeitos adversos , Diagnóstico Diferencial
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