1.
Bioorg Med Chem Lett
; 18(24): 6476-8, 2008 Dec 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18990573
RESUMO
Oxinobactin, a siderophore analogue to enterobactin but possessing 8-hydroxyquinoline instead of catechol complexing subunits, has been synthesized starting from L-serine and 8-hydroxyquinoline. Comparative iron binding studies showed that oxinobactin is as effective as enterobactin for the complexation of Fe(III) at physiological pH but with improved complexing ability at acidic pH.