RESUMO
Erythema elevatum diutinum (EED) has been emerging as a specific Human Immunodeficiency Virus (HIV) associated dermatosis in recent times. It is an extremely rare chronic disease of unknown origin and part of the spectrum of leukocytoclastic vasculitis. We describe a case of EED simulating Kaposi's sarcoma in a 52-year-old HIV infected female patient with no previous opportunistic infections and CD4+ count of 164/mm(3). Therapy with oral dapsone (100 mg/day) for two weeks resulted in resolution of some lesions.
RESUMO
Large congenital melanocytic nevi (> 20 cm in greatest diameter) are very rare and are seen in approximately 1 in 20,000 newborns. The major risk these patients face is the development of neurocutaneous melanosis or malignant melanoma. We report a rare case of large congenital melanocytic nevus with metastatic melanoma in a 40-year-old woman. In this case, though the primary was not established with certainty, on the basis of clinical course and radiological evaluation of various organs, we presume that the primary could be in the lung.
Assuntos
Neoplasias Encefálicas/secundário , Neoplasias Pulmonares/patologia , Melanoma/secundário , Neoplasias Primárias Múltiplas/patologia , Nevo Pigmentado/congênito , Neoplasias Cutâneas/congênito , Biópsia por Agulha , Neoplasias Encefálicas/patologia , Neoplasias Encefálicas/terapia , Terapia Combinada , Progressão da Doença , Evolução Fatal , Feminino , Humanos , Imuno-Histoquímica , Neoplasias Pulmonares/diagnóstico por imagem , Neoplasias Pulmonares/terapia , Melanoma/diagnóstico , Melanoma/terapia , Pessoa de Meia-Idade , Neoplasias Primárias Múltiplas/diagnóstico por imagem , Neoplasias Primárias Múltiplas/terapia , Nevo Pigmentado/patologia , Nevo Pigmentado/terapia , Radiografia Torácica , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/terapia , Tomografia Computadorizada por Raios X/métodosAssuntos
Hanseníase Dimorfa/complicações , Hanseníase Tuberculoide/complicações , Hanseníase Tuberculoide/patologia , Lúpus Vulgar/complicações , Lúpus Vulgar/patologia , Adolescente , Antituberculosos/uso terapêutico , Biópsia por Agulha , Seguimentos , Humanos , Imuno-Histoquímica , Hansenostáticos/uso terapêutico , Hanseníase Dimorfa/tratamento farmacológico , Hanseníase Tuberculoide/tratamento farmacológico , Lúpus Vulgar/tratamento farmacológico , Masculino , Medição de Risco , Índice de Gravidade de Doença , Resultado do TratamentoRESUMO
A 48 year old woman presented with high grade fever, arthralgia and multiple tender papules and plaques over the face, neck, back, arms and forearms with distension of abdomen. Investigations revealed leukocytosis with neutrophilia, high ESR and increased C-reactive protein. Skin biopsy showed neutrophilic infiltration in the dermis. Plain x-ray abdomen is suggestive of subacute intestinal obstruction. We report this case of classic Sweet's syndrome with uncommon presentation.