A case of large-cell undifferentiated carcinoma of the bladder.

Large-cell undifferentiated carcinoma of the urinary bladder is an extremely rare and aggressive neoplasm. We present a unique case of painless gross hematuria and a past surgical history of cystolithotomy. The patient underwent transurethral resection of the bladder tumor, which revealed high-grade urothelial cell carcinoma with lamina propria involvement. Subsequent radical cystoprostatectomy with orthotopic neobladder urinary diversion and pelvic lymphadenectomy was performed, and the postoperative pathologic examination indicated large-cell undifferentiated. This case report highlights the importance of accurate diagnosis and management for this rare malignancy and adds to the limited existing literature on Large-cell undifferentiated carcinoma.

Benign cystic Teratoma and Gonadoblastoma developed in bilateral abdominal undescended testis.

Cryptorchidism is one of the most common congenital malformations in humans and one of its most important consequences is the development of testicular cancer. While germ cell tumors (GCTs) and sex cord-stromal tumors are major testicular tumors. Gonadoblastoma is a rare neoplasm composed of a combination of germ cells and gonadal stromal elements. In this study we present a patient with bilateral abdominal undescended testis with gonadobelastoma in the left and benign cystic teratoma in the right testicle.