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1.
Artigo em Inglês | MEDLINE | ID: mdl-38865574

RESUMO

Women living with human immunodeficiency virus are at an increased risk of developing cancers related to human papillomavirus (HPV). Thus, it is important to combine clinical assessments, serological screening, and HPV data for planning prevention policies. This study aimed to identify HPV and its specific types in the cervical, anal, and oral mucosa of HIV-seropositive women, associating it with viral load and lymphocyte count. Sociodemographic characteristics, health data (CD4+ and CD8+ T cell counts and viral load), and biological samples (cervical, anal, and oral) were collected from 86 HIV-positive women undergoing antiretroviral therapy. Data were classified according to the presence or absence of HPV-DNA, HPV-DNA presence at one or more anatomic sites, and level of oncogenic risk, considering low- and high-risk oncogenic HPV-DNA groups. The presence of HPV in the cervicovaginal site was 65.9%, 63.8% in anal canal, and 4.2% in oral mucosa. A viral load ≥75 HIV copies/mL was associated with the presence of HPV-DNA. There was an association between viral load and the low-risk HPV or high-risk HPV groups. We found a high prevalence of HPV infection in HIV-seropositive women, particularly in the cervical and anal mucosa, with viral load ≥75 HIV copies/mL being associated with HPV-DNA presence.


Assuntos
Colo do Útero , DNA Viral , Infecções por HIV , Infecções por Papillomavirus , Carga Viral , Humanos , Feminino , Infecções por Papillomavirus/complicações , Adulto , Infecções por HIV/complicações , Infecções por HIV/virologia , DNA Viral/análise , Colo do Útero/virologia , Papillomaviridae/genética , Papillomaviridae/isolamento & purificação , Pessoa de Meia-Idade , Contagem de Linfócitos , Mucosa Bucal/virologia , Canal Anal/virologia , Prevalência , Estudos Transversais , Fatores Socioeconômicos , Contagem de Linfócito CD4 , Fatores de Risco , Papillomavirus Humano
2.
J Med Case Rep ; 18(1): 216, 2024 May 02.
Artigo em Inglês | MEDLINE | ID: mdl-38693545

RESUMO

BACKGROUND: Orbital metastasis is a possible complication of small cell lung cancer and a pattern of bilateral invasion of the extraocular muscles has rarely been reported in literature. CASE PRESENTATION: A 46-year-old white male with a past medical history of smoking and stage IV small cell lung carcinoma presented with loss of vision and pain in the left eye. Examination revealed bilateral proptosis and left afferent pupillary defect, and visual acuity was hand motion on the left eye and 4/10 on the right eye. An orbital computed tomography scan showed a compression of the left optic nerve between the extraocular muscles at the apex, and a lateral canthotomy was performed for a new-onset compressive optic neuropathy, with residual visual improvement. There was also significant enlargement of the extraocular muscles in the right orbit. The patient was maintained in palliative treatment with both chemotherapy and local medical and surgical (amniotic membrane cover for exposure keratopathy) ophthalmological treatments until he eventually died 5 months after. CONCLUSION: Bilateral metastasis to the extraocular muscles is a very rare manifestation of small cell lung cancer and the palliative treatment in these cases is challenging.


Assuntos
Neoplasias Pulmonares , Músculos Oculomotores , Carcinoma de Pequenas Células do Pulmão , Humanos , Masculino , Pessoa de Meia-Idade , Evolução Fatal , Neoplasias Pulmonares/patologia , Músculos Oculomotores/patologia , Músculos Oculomotores/diagnóstico por imagem , Neoplasias Orbitárias/secundário , Neoplasias Orbitárias/cirurgia , Neoplasias Orbitárias/diagnóstico por imagem , Cuidados Paliativos , Carcinoma de Pequenas Células do Pulmão/patologia , Tomografia Computadorizada por Raios X
3.
Case Rep Ophthalmol ; 15(1): 250-255, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38524876

RESUMO

Introduction: Conjunctival cysts of the orbit development are a rare complication in enucleated patients. They result from the entrapment of conjunctival epithelium within the orbit. Case Presentation: We report the case of a 25-year-old man with a history of enucleation for a retinoblastoma of the right eye who presented with difficulty in fitting his eye prothesis. On his past medical records, there was no reference to the placement of any orbital implant at the time of the surgery. Biomicroscopy of the right eye revealed a thickened bulbar conjunctiva, an inferior symblepharon, and a translucid central area with vascularization. Imaging was remarkable for a cystic cavity filling the whole right orbit. Biopsy revealed the diagnosis of a conjunctival cyst, and drainage was performed, alleviating the patient's symptoms. Conclusion: Orbital conjunctival cysts may pose a clinical problem, and treatment modalities include surgical excision, absolute alcohol injection, and trichloroacetic acid injection.

4.
Mar Pollut Bull ; 200: 116088, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38309176

RESUMO

In 2019, an oil spill hit the Brazilian Northeast coast causing impact to several ecosystems, including sea turtles' breeding and feeding areas. This study aimed to investigate whether sea turtles were impacted by this oil disaster, correlating the oil found inside feces with a sandy-oiled sample collected on the beach some days after the accident. The fecal samples were collected in the upper mid-littoral reef areas during three consecutive days in February 2020. The results suggested that sea turtles consumed algae contaminated by petroleum. Hydrocarbons composition of oil inside feces was similar to the sandy-oiled sample, suggesting they were the same. Lighter aliphatic and polycyclic aromatic compounds were missing, indicating both sandy-oiled and oil inside the feces had experienced significant evaporation prior to collection. Although the long-term damage is still unknown, the data are novel and relevant to support future research and alert authorities about the risks to sea turtles.


Assuntos
Poluição por Petróleo , Petróleo , Hidrocarbonetos Policíclicos Aromáticos , Tartarugas , Poluentes Químicos da Água , Animais , Monitoramento Ambiental , Ecossistema , Petróleo/análise , Hidrocarbonetos Policíclicos Aromáticos/análise , Poluentes Químicos da Água/análise
5.
Int J Cardiovasc Imaging ; 40(2): 415-424, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37943369

RESUMO

The aim is to evaluate the diagnostic yield of echocardiography and [99mTc]Tc-DPD scintigraphy in the detection of amyloid cardiomyopathy (CM) and define potential prognostic echocardiographic parameters. 133 patients were retrospectively studied, from 2016 to 2021, with a mean age of 80.2 ± 7.5 years. The final diagnosis was established according to international consensus. Patients had a transthoracic echocardiogram (TTE) and [99mTc]Tc-DPD scintigraphy; RWT, E/e, LS, TAPSE, SAB, and IWT scores were calculated. All patients with ATTR-CM were classified into 3 prognostic stages and were compared with Perugini grades and echocardiographic parameters. CM was confirmed in 85 cases (63.9%), 76 (57.1%) ATTR-CM, and 9 (6.8%) AL-CM. The diagnostic yield of [99mTc]Tc-DPD scintigraphy and echocardiography were calculated, with a sensitivity of 90.7%, specificity of 100%, PPV of 100%, and NPV of 87.2% in myocardial scintigraphy, versus 74.6%, 62.5%, 75.6%, 61.2% in the echocardiogram. According to the IWT score, most patients were classified in the intermediate group; 33 presented with grade 2-3 uptakes. Significant results were obtained when comparing Perugini score with IWT (p: 0.02) and SAB (p: 0.03); and between biomarkers stages and LVEF (p: 0.028), E/e´ (p: 0.001), and GLS% (p: 0.022). [99mTc]Tc-DPD scintigraphy is superior in diagnosing CA. SAB could be the most reliable parameter in an early diagnostic phase, showing a strong correlation with Perugini grades 2 and 3.


Assuntos
Neuropatias Amiloides Familiares , Cardiomiopatias , Humanos , Idoso , Idoso de 80 Anos ou mais , Pré-Albumina , Neuropatias Amiloides Familiares/diagnóstico por imagem , Estudos Retrospectivos , Valor Preditivo dos Testes , Ecocardiografia , Cintilografia , Cardiomiopatias/diagnóstico por imagem
6.
Braz. oral res. (Online) ; 38: e011, 2024. tab, graf
Artigo em Inglês | LILACS-Express | LILACS, BBO | ID: biblio-1528154

RESUMO

Abstract This observational study aimed to describe and analyze data from two external evaluations of the National Program for Improving Access to and Quality of Dental Specialty Centers (PMAQ CEO), held in 2014 and 2018 in Brazil, which evaluated Dental Specialty Centers (CEO) using a national and census approach. We selected questions through a search in the microdata of the first and second evaluations. The groups were analyzed independently. To compare the groups, nonparametric tests were performed (Mann Whitney U). The formulated hypotheses were: there would be no differences between the data of these groups (h0) and there would be differences between the data of these groups (h1). For qualitative nominal variables, frequency distribution was verified and association tests were performed (chi-square test). The significance level for this study was set at 5%. We observed that orthodontic treatments were found in about 13% of the CEO. Regarding human resources, most professionals were specialists or had MSc or PhD degrees; were civil servants; had been hired by direct administration; or had been hired via public tender. Regarding the work process and inclusion of the CEO in the health care network, we observed a greater number of services that use single and electronic medical records, greater presence of services monitoring and analyzing goals, greater knowledge about monthly average of absenteeism (for 2018); and larger number of services with referrals from primary health care centers (for 2014). Expanding the view on orthodontics and including preventive, interceptive, and corrective treatments at different points in health care networks are essential strategies for achieving comprehensive care in universal health systems.

7.
Artigo em Espanhol | LILACS, BINACIS | ID: biblio-1552152

RESUMO

Introducción: Las osteotomías supramaleolares son una opción terapéutica para la artrosis asimétrica de tobillo. El objetivo de este artículo es describir los resultados clínicos, radiográficos y subjetivos obtenidos en pacientes con artrosis de tobillo sometidos a una osteotomía supramaleolar. Materiales y métodos: Estudio observacional descriptivo retrospectivo de pacientes sometidos a una osteotomía supramaleolar por artrosis de tobillo entre enero de 2010 y julio de 2017. Se analizaron las historias clínicas para recabar datos clínicos y radiográficos preoperatorios y posoperatorios. Resultados: Se incluyó a 13 pacientes: 8 con una desalineación del tobillo y retropié en valgo (61,5%) y 5 (38,5%) en varo. El puntaje medio posoperatorio de la escala analógica visual del grupo con deformidad en varo disminuyó de 9 ± 0,45 a 3 ± 1 (p <0,05) y de una media de 7,88 ± 0,35 a 2,15 ± 1,64 (p <0,05) en aquellos con deformidad en valgo. El puntaje medio de la escala de la AOFAS se modificó de 32,8 ± 16,2 antes de la cirugía a 82,1 ± 13,6 en el posoperatorio, en el grupo con deformidad en varo (p <0,05) y de 31 ± 17,3 a 93,1 ± 6,20, respectivamente, en aquellos con deformidad en valgo (p <0,05). Se constató la consolidación radiográfica en 12 pacientes (92,3%), en un promedio de 10.4 semanas. Conclusión:La osteotomía supramaleolar como tratamiento de la artrosis asimétrica de tobillo es una técnica predecible, con muy buenos resultados clínicos y radiográficos a corto y mediano plazo. Nivel de Evidencia: IV


Introduction: Supramalleolar osteotomies are a treatment option for asymmetric ankle osteoarthritis. Our work aims to describe the clinical, radiographic, and subjective outcomes obtained in patients with ankle osteoarthritis who underwent a supramalleolar osteotomy (SMOT). Materials and methods: Retrospective, observational, and descriptive study on patients who underwent SMOT for ankle osteoarthritis between January 2010 and July 2017. The patients' clinical records were analyzed. Results: We included 13 patients who underwent SMOT, 8 patients with valgus (61.5%) and 5 (38.5%) with varus rearfoot and ankle misalignment. The mean varus VAS score decreased from 9 ± 0.45 to 3 ± 1 postoperatively (p <0.05) and, in valgus deformities, from a mean 7.88 ± 0.35 to 2.15 ±1.64 postoperatively (p <0.05). The mean AOFAS score changed from 32.8 ± 16.2 to 82.1 ± 13.6 postoperatively in the varus deformity group (p <0.05) and from 31 ± 17.3 preoperatively to 93.1 ± 6.20 postoperatively in the valgus deformity group (p <0.05). Twelve patients (92.3%) achieved radiographic union in an average time of 10.4 weeks. Conclusion:Supramalleolar osteotomy as a treatment for asymmetric ankle osteoarthritis is a predictable technique with very good clinical and radiological outcomes in the short and medium term. Level of Evidence: IV


Assuntos
Pessoa de Meia-Idade , Osteoartrite , Osteotomia , Resultado do Tratamento , Articulação do Tornozelo
8.
Rev. Fac. Odontol. Porto Alegre ; 64(1): e131417, dez 2023.
Artigo em Português | LILACS-Express | LILACS | ID: biblio-1526464

RESUMO

Aim: to analyze, between 2019-2021, the quantitative changes in dental emergencies (DE) in Brazil and its regions. Materials and Methods: Data collected in the Primary Care Health Information System (SISAB) from 2019 to 2021. The DE represented by dentoalveolar abscess (DAA) and toothache (TA). 2019 was the control (non-pandemic), and 2020-21 the exposure year. Durbin-Conover's Friedman and Post-Hoc tests used a significance level of 5%. The data's organization used the percentage difference to facilitate analysis. Results: For Brazil in 2021, the percentage difference with 2019 suggests that DAA (-2.16%, p=1.0) and TA (+14.94%, p=0.064) returned to values after fall of 2020. The South region, in 2020, had no decrease in DAA (-5.48%, p=0.436) and TA (+3.7%, p<0.001) in 2020, and an increase in both in 2021 (DAA: +26.86%, p<0.001; TA: +51.06%, p<0.001). Discussion: In 2021, in Brazil, limited elective access and resumption of DAA and increase in TA suggest worsening the oral health and quality of life. The DAA and TA results in the South region do not provide plausible evidence to understand the unchanged values in 2020 and the considerable increase in 2021. Conclusion: Regardless of the pandemic, elective access still struggles to offer universal acessing, equitable, and the need of investments are essentials to prevent public services from becoming just gateways for relieving pain and suffering.


Objetivo: analisar, entre 2019-2021, as alterações quantitativas nas urgências odontológicas (UO) no Brasil e suas regiões. Materiais e Métodos: Dados coletados no Sistema de Informação em Saúde da Atenção Básica (SISAB) no período de 2019 a 2021. A representação das UO foi pelo abscesso dento-alveolar (ADA) e dor de dente (DD). O ano de 2019 foi o ano de controle (não pandêmico) e 2020-21 os de exposição. Os testes Friedman e Post-Hoc de Durbin-Conover utilizaram nível de significância de 5%. Os dados foram organizados pela diferença percentual para facilitar a análise. Resultados: Para o Brasil em 2021, a diferença percentual com 2019 sugerem que o ADA (-2,16%, p=1,0) e a DD (+14,94%, p=0,064) retomaram os valores, após a queda de 2020. A região Sul, em 2020, não teve queda em ADA (-5,48%, p=0,436) e DD (+3,7%, p<0,001) em 2020, e aumento em ambos em 2021 (ADA: +26,86%, p<0,001; DD: +51,06%, p<0,001). Discussão: Em 2021, no Brasil, o limitado acesso eletivo e a retomada da ADA e aumento da DD sugerem piora na saúde bucal e na qualidade de vida. Os resultados de ADA e DD na região Sul não apresentam evidências plausíveis para compreender a inalteração de valores em 2020 e o considerável aumento em 2021. Conclusão: Independentemente a pandemia, o acesso eletivo ainda luta para ser universal, equânime e os investimentos precisam ser retomados para evitar que os serviços públicos se tornem em apenas portas de entrada de alívio dor e sofrimento.

9.
Rev. enferm. UERJ ; 31: e76901, jan. -dez. 2023.
Artigo em Inglês, Português | LILACS-Express | LILACS | ID: biblio-1527031

RESUMO

Objetivo: evidenciar os diagnósticos social e epidemiológico de trabalhadores da saúde atuantes na pandemia e acometidos por COVID-19, aplicando modelo PRECEDE-PROCEED. Métodos: estudo documental, quantitativo, observacional, retrospectivo, desenvolvido a partir do modelo PRECEDE-PROCEED, que norteia intervenções, partindo do diagnóstico faseado para implementar ações. Dados obtidos em 215 prontuários de trabalhadores com COVID-19, atendidos no serviço ocupacional hospitalar em Macapá, entre 2020 e 2021. Resultados: diagnóstico social: mulheres (81,9%), pardas/pretas (79%), idade entre 40/55 anos (53,4%), técnicas de enfermagem (40%), da nefrologia (10,2%), vínculo estadual/federal (91,6%) superior a 10 anos (60,4%). Diagnóstico Epidemiológico: cefaleia (53,5%), tosse (51,6%), febre (47,9%). Teste rápido (76,3%), atendimento ambulatorial (90,2%), afastamento de 8 a 14 dias (45,1%), 100% curados, sequelas em 12,6%. Sem diferença significativa quanto ao afastamento por função exercida. Dispneia, dor torácica e sequelas da doença tem maior chance de afastamento. Conclusão: a aplicação do modelo possibilita planejar ações de conscientização/prevenção sobre risco, adoecimento, acidente laboral e cuidados à saúde dos trabalhadores.


Objective: to highlight the social and epidemiological diagnoses of health workers working in the pandemic and affected by COVID-19, applying the PRECEDE-PROCEED model. Methods: documentary, quantitative, observational, retrospective study, developed based on the PRECEDE-PROCEED model, which guides interventions, starting from phased diagnosis to implement actions. Data obtained from 215 medical records of workers with COVID-19, treated at the hospital occupational service in Macapá, between 2020 and 2021. Results: social diagnosis: women (81.9%), brown/black (79%), aged between 40/ 55 years old (53.4%), nursing technicians (40%), nephrology (10.2%), state/federal employment (91.6%) for more than 10 years (60.4%). Epidemiological Diagnosis: headache (53.5%), cough (51.6%), fever (47.9%). Rapid test (76.3%), outpatient care (90.2%), sick leave of 8 to 14 days (45.1%), 100% cured, sequelae in 12.6%. No significant difference in terms of leave by function performed. Dyspnea, chest pain and sequelae of the disease have a greater chance of sick leave. Conclusion: the application of the model makes it possible to plan awareness/prevention actions regarding risk, illness, occupational accidents and workers' health care.


Objetivo: visibilizar los diagnósticos social y epidemiológico de los trabajadores de la salud que trabajan en la pandemia y afectados por el COVID-19, aplicando el modelo PRECEDE-PROCEED. Métodos: estudio documental, cuantitativo, observacional, retrospectivo, desarrollado con base en el modelo PRECEDE-PROCEED, que orienta las intervenciones, a partir del diagnóstico por fases para implementar de acciones. Los datos se obtuvieron de 215 historias clínicas de trabajadores con COVID-19, atendidos en el servicio ocupacional hospitalario de Macapá, entre 2020 y 2021. Resultados: diagnóstico social: mujeres (81,9%), morenas/negras (79%), edades entre 40/ 55 años (53,4%), técnicos en enfermería (40%), del área de nefrología (10,2%), empleo estatal/federal (91,6%) con más de 10 años (60,4%). Diagnóstico Epidemiológico: dolor de cabeza (53,5%), tos (51,6%), fiebre (47,9%). Prueba rápida (76,3%), atención ambulatoria (90,2%), baja laboral de 8 a 14 días (45,1%), 100% curados, secuelas en un 12,6%. No hay diferencia significativa en términos de licencias por función desempeñada. La disnea, el dolor torácico y las secuelas de la enfermedad tienen mayor probabilidad de ocasionar la baja laboral. Conclusiones: la aplicación del modelo permite planificar acciones de concienciación/prevención en cuanto al riesgo, enfermedades, accidentes laborales y atención de la salud de los trabajadores.

10.
BMJ Case Rep ; 16(11)2023 Nov 14.
Artigo em Inglês | MEDLINE | ID: mdl-37963665

RESUMO

A female patient in her 20s presented to a routine ophthalmology appointment. Medical history was unremarkable. Family history was notable for intestinal cancer of a second-degree relative, diagnosed in her late 60s. Fundus examination revealed bilateral, multiple, flat, oval, pigmented lesions with an irregular halo of atrophy. The patient was diagnosed with atypical congenital hypertrophy of retinal pigmented epithelium. Investigation of extraocular associations was performed, including upper and lower endoscopy, which revealed 500-1000 colonic polyps with a maximum size 25 mm. Pathology did not reveal submucosal invasion. Genetic testing detected an adenomatous polyposis coli mutation (heterozygotic variant c.3183_3187delACAAA p.(Gln1062*)).


Assuntos
Polipose Adenomatosa do Colo , Epitélio Pigmentado da Retina , Humanos , Feminino , Epitélio Pigmentado da Retina/patologia , Polipose Adenomatosa do Colo/complicações , Polipose Adenomatosa do Colo/diagnóstico , Polipose Adenomatosa do Colo/genética , Fundo de Olho , Hipertrofia/congênito , Testes Genéticos
11.
Artigo em Português | LILACS-Express | LILACS | ID: biblio-1525612

RESUMO

Antropologia Forense é uma área da antropologia biológica que pode ser definida como o estudo científico de restos e/ou ossadas humanas, corpos ou parte de corpos que precisam de identificação. Quando uma ossada imatura é encontrada, é possível que ela seja confundida com ossos animais, devido às semelhanças nos formatos e tamanho dos ossos. Além disso, a avaliação da viabilidade fetal está relacionada à estimativa de idade e esses dados também são relevantes em contextos jurídicos, quando se envolvem temas como aborto ou infanticídio. O objetivo desse estudo foi descrever a utilização de um tradicional método de estimativa de idade (Fazekas e Kósa, 1978) em esqueletos fetais e verificar sua aplicabilidade no contexto local, com as amostras do Núcleo de Medicina e Odontologia Legal (NUMOL) de João Pessoa/PB. De acordo com o método, foram mensurados 6 ossos longos (úmero, rádio, ulna, fêmur, tíbia e fíbula) de 4 esqueletos disponíveis. O menor esqueleto analisado teve sua idade estimada entre 18 e 20 semanas e o maior 40 semanas. No único esqueleto catalogado do acervo, a estimativa de idade mostrou-se efetiva, abrangendo a idade real. Nesse contexto, alerta-se para a necessidade de se estabelecer corretamente a idade fetal em casos forenses, o que possibilita responder questionamentos jurídicos, sobretudo quanto à viabilidade da vida intrauterina, trazendo luz as possibilidades de possíveis crimes de aborto ou infanticídio. Ademais, o estudo mostrou-se como um norteador nos trabalhos periciais com a difusão do método, sua execução e aplicação. Contudo, faz-se necessário que novos estudos sejam desenvolvidos buscando a confiabilidade do método com base em ossadas locais e atuais


Forensic Anthropology is a field of biological anthropology that can be defined as the scientific study of human remains and/or bones, bodies or body parts that require identification. When immature bones are found, they may be mistaken for animal bones due to similarities in shape and size. In addition, fetal viability assessment is related to age estimation, and this data is also relevant in legal contexts, when issues such as abortion or infanticide are involved. The objective of this study was to describe the use of a traditional age estimation method (Fazekas and Kósa, 1978) in fetal skeletons and to verify its applicability in the local context, using samples from the Nucleus of Legal Medicine and Dentistry (NUMOL) in João Pessoa/PB, Brazil. According to the method, six long bones (humerus, radius, ulna, femur, tibia, and fibula) from four available skeletons were measured. The smallest skeleton analyzed had its age estimated between 18 and 20 weeks, and the largest was 40 weeks. In the only cataloged skeleton in the collection, the age estimation was effective, encompassing the real age. In this context, the need to establish fetal age correctly in forensic cases is emphasized, which makes it possible to answer legal questions, especially regarding the viability of intrauterine life, shedding light on the possibilities of possible crimes of abortion or infanticide. Moreover, the study proved to be a guide in forensic work with the dissemination of the method, its execution, and application. However, it is necessary to develop new studies seeking the reliability of the method based on local and current skeletal remains

12.
Gen Comp Endocrinol ; 344: 114375, 2023 12 01.
Artigo em Inglês | MEDLINE | ID: mdl-37696482

RESUMO

In cururu stingray (Potamotrygon wallacei Carvalho, Rosa and Araújo 2016) males, plasma progesterone (P4) levels appear to be associated with spermiation events. However, the specific contribution of P4 in sperm maturation via extratesticular ducts in this stingray species is unknown. With the aim of filling this knowledge gap, this study examined the morphology and the presence of progesterone receptors (PR) in the ducts, and analyzed the relationship of progesterone (P4) with sperm maturation and formation of aggregates. Morphological analysis showed that a columnar pseudostratified epithelium with stereocilia lined all the attached ducts. In active males, the secretory cells of the epididymis and the Leydig glands presented PR; however, these receptors were not found in the distal region of the epididymis (essential for nurturing and capacitation events) of regressing males. In the seminal vesicles of active males, the spermatozoa are parallelly aligned and embedded in a matrix to form the spermatozeugmata. The matrixes are formed by proteins secreted by the ducts and Sertoli cell cytoplasts. These structures presented PR, which suggests that P4 engages in sperm metabolism during storage. Our findings allude to the potential role of P4 in regulating the development and function of the attached ducts in different reproductive phases. Furthermore, P4 seems to be an essential component for regulating sperm progress, protein secretion, aggregate formation, and maintenance of sperm during storage in this freshwater stingray.


Assuntos
Elasmobrânquios , Rajidae , Animais , Masculino , Rajidae/metabolismo , Receptores de Progesterona/metabolismo , Progesterona/metabolismo , Maturação do Esperma , Sêmen/metabolismo , Espermatozoides/metabolismo , Epididimo/metabolismo
13.
Arq Bras Cir Dig ; 36: e1753, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37531473

RESUMO

BACKGROUND: Vitamin, mineral, and metabolic deficiencies occur in the postoperative period of bariatric surgery, in the short and long term, and are worrisome intercurrences. AIMS: To evaluate the association of serum vitamin D levels with the lipid profile in obese patients undergoing bariatric surgery. METHODS: Case series of patients assisted from 2010 to 2018, in a private hospital of medium and high complexity, who underwent bariatric surgery using sleeve gastrectomy or Roux-en-Y gastric bypass techniques, monitored by the same surgeon. Sociodemographic, clinical, laboratory, and anthropometric data were collected preoperatively and at 6, 12, and 24 months after surgery. RESULTS: A total of 156 individuals, mostly female (75.6%) were monitored. The most frequent comorbidities were hepatic steatosis (76.3%) and hypertension (48.27). Regarding preoperative vitamin D levels, only 18.9% of the population had a satisfactory level (≥30 ng/mL). There was a reduction in weight and an improvement in the lipid profile after surgery. Significant correlations were observed between the lipid profile and vitamin D concentration only in the sample submitted to the Roux-en-Y gastric bypass technique: negative correlation between total cholesterol and vitamin D two years after surgery; positive correlation between triglycerides and vitamin D one year after surgery; and negative correlation between high-density lipoprotein and vitamin D two years post-surgery. CONCLUSIONS: It is essential to routinely monitor vitamin D levels and lipid profile pre- and postoperatively in order to avoid damage associated with this vitamin deficiency.


Assuntos
Cirurgia Bariátrica , Derivação Gástrica , Obesidade Mórbida , Humanos , Feminino , Masculino , Vitamina D , Obesidade Mórbida/complicações , Cirurgia Bariátrica/métodos , Derivação Gástrica/métodos , Vitaminas , Gastrectomia , Lipídeos , Estudos Retrospectivos
14.
Distúrb. comun ; 35(2): 57752, 02/08/2023.
Artigo em Inglês, Português | LILACS | ID: biblio-1452416

RESUMO

Introdução: A reabilitação vestibular (RV) surge como uma opção terapêutica em casos de tontura e desequilíbrio postural. O The Activities-specific Balance Confidence Scale (ABC Scale) é um questionário utilizado para avaliar a interferência destes sintomas vestibulares por meio do nível de confiança dos indivíduos em realizar atividades diárias que envolvem o equilíbrio postural. Objetivo: comparar o nível de confiança na realização de atividades diárias relacionadas ao equilíbrio corporal, pré e pós reabilitação vestibular (RV) em pacientes com disfunção vestibular. Método: Estudo primário, intervencional, clínico, longitudinal, prospectivo, analítico, não controlado. Participaram 14 indivíduos, do sexo feminino e masculino, portadores de vestibulopatia periférica. Foi aplicado o Activities-specific Balance Confidance Scale (ABC Scale) nas condições pré e pós RV. Os dados foram analisados de forma descritiva e inferencial, pelos testes Exato de Fisher, t-Sudent e o modelo linear de efeitos mistos. Resultados: A amostra se caracterizou por 78.57% do sexo feminino e 21.43% do sexo masculino, com média de idade de 59.21 anos. Observou-se diferença estatística quando comparados os resultados do ABC Scale nas condições pré e pós RV (p<0.0001). Não foi verificada diferença estatística entre os escores deste instrumento com as variáveis sexo, idade e número de sessões terapêuticas. Conclusão: Foi possível concluir que o nível de confiança dos pacientes dessa amostra modificou de baixo, na fase pré reabilitação, para alto, na fase final da intervenção, o que consolida a ocorrência do aumento no nível de confiança que acarretou melhoria na qualidade de vida. (AU)


Introduction: Vestibular rehabilitation (VR) appears as a therapeutic option in cases of dizziness and postural imbalance. The Activities-specific Balance Confidence Scale (ABC Scale) is a questionnaire used to assess the interference of these vestibular symptoms with the individuals' level of confidence to carry out daily activities involving postural balance. Objective: to compare the level of confidence to carry out daily activities related to body balance, before and after VR, in patients with vestibular dysfunction. Method: Primary, interventional, clinical, longitudinal, prospective, analytical, and noncontrolled study. The sample comprised 14 male and female individuals with peripheral vestibulopathy. The ABC Scale was applied before and after VR. Descriptive and inferential data analysis were performed, using Fisher's Exact test, Student's t-test, and the linear mixed-effects model. Results: The sample had 78.57% females and 21.43% males, with a mean age of 59.21 years. There was a statistical difference in ABC Scale results before and after VR (p < 0.0001). There was no statistical difference between its scores and sex, age, or the number of therapy sessions. Conclusion: It was concluded that this study patients' confidence level changed from low in the pre-rehabilitation phase, to high in the final phase of the intervention, which consolidates the increase in confidence level that led to an improvement of quality of life. (AU)


Introducción: La rehabilitación vestibular (RV) aparece como una opción terapéutica en casos de mareos y desequilibrio postural. La Escala de Confianza en el Equilibrio Específica de Actividades (Escala ABC) es un cuestionario utilizado para evaluar la interferencia de estos síntomas vestibulares a través del nivel de confianza de los individuos en la realización de actividades diarias que involucran el equilibrio postural. Objetivo: comparar el nivel de confianza en la realización de actividades cotidianas relacionadas con el equilibrio corporal, pre y post rehabilitación vestibular (RV) en pacientes con disfunción vestibular. Método: Estudio primario, intervencionista, clínico, longitudinal, prospectivo, analítico, no controlado. Participaron 14 individuos, hombres y mujeres y con vestibulopatía periférica. La Escala de Confianza del Equilibrio Específica de Actividades (Escala ABC) se aplicó en condiciones previas y posteriores a la RV. Los datos fueron sometidos a análisis descriptivo e inferencial mediante la prueba exacta de Fisher, t-Sudent y el modelo lineal de efectos mixtos. Resultados: La muestra se caracterizó por 78,57% del sexo femenino y 21,43% del masculino, con una edad media de 59,21 años. Hubo diferencia estadística al comparar los resultados de la Escala ABC en condiciones pre y post RV (p<0,0001). No hubo diferencia estadística entre los puntajes de este instrumento con las variables sexo, edad y número de sesiones terapéuticas. Conclusión: Fue posible concluir que el nivel de confianza de los pacientes de esta muestra pasó de bajo, en la fase de pre-rehabilitación, a alto, en la fase final de la intervención, lo que consolida la ocurrencia del aumento en el nivel de confianza que llevó a una mejora en la calidad de vida. (AU)


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Idoso , Atividades Cotidianas/psicologia , Confiança/psicologia , Vertigem/reabilitação , Inquéritos e Questionários , Estudos Retrospectivos , Tontura/reabilitação , Doenças do Labirinto/terapia
15.
Waste Manag ; 168: 179-188, 2023 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-37302176

RESUMO

This study assessed the extent of cigarette butt contamination on two urban beaches in Recife-PE (Pernambuco State, Brazil) with varying levels of use. The study considered degradation levels and evaluated whether the brands varied by time, space, and beaches use. Ten transects (1.5 m wide) and spaced 10 m apart, were delimited on the beaches investigated. Twelve collections were made between May 2021 and January 2022, and the collected cigarette butts were evaluated based on degradation level, mass, size, and brand. In total, 10,275 cigarette butts were collected on both beaches, with P1 accounting for 96.91% of the found cigarette butts. The density of cigarette butts on the beaches was directly proportional to the level of use, with 8.85 butts/m2 in P1 and 1.05 butts/m2 in P2. Eighteen brands were identified, with brand (A) being the most popular regardless of the area. Significant differences (p ≤ 0.05) were found when evaluating the amount of butts/m2; Sundays with high precipitation presented reduced values of butts; more occupied areas presented transects with higher amounts; abundance in the summer; morphometry with higher values recorded in newly discarded butts; predominance of more degraded butts and brand diversity. Despite the difference in the number of butts/m2 between the areas, it was possible to identify that their abundance is very expressive, and that the monitored beaches present a high exposure to the contaminant.


Assuntos
Fumar , Produtos do Tabaco , Brasil , Monitoramento Ambiental , Praias
16.
Rev. Ciênc. Méd. Biol. (Impr.) ; 22(1): 90-97, jun 22, 2023. fig, tab
Artigo em Português | LILACS | ID: biblio-1443288

RESUMO

Introdução: as parasitoses intestinais são doenças que apresentam um problema de saúde mundial, causando grandes problemas nutricionais, onde sua ocorrência varia de acordo com o clima de cada região e condições socioeconômicas. Regiões que apresentam climas trópicos com umidade, altos índices de chuvas e temperaturas elevadas associadas com a falta de informações sobre as enteroparasitoses merecem atenção. Objetivo: o presente trabalho buscou avaliar os tipos de enteroparasitoses entre os anos de 2018 a 2020 em uma parcela da população de um município da Amazônia Ocidental, mais especificamente, (i) avaliar os tipos de enteroparasitoses que acometem a população entre os períodos de inundação e estiagem; (ii) avaliar a influência das enteroparasitoses em indivíduos de acordo com o gênero e a faixa etária ao longo de três anos. Metodologia: as coletas de dados foram realizadas entre os anos de 2018 a 2020, por meio de análises de planilhas concedidas pelo laboratório de análises clinicas LABSUL. Resultados: foram avaliados 4236 exames de fezes, sendo que apenas 1396 foram positivos para enteroparasitoses. Dos quais a maior parte foi causada por protozoários (58,69%) que acometeram principalmente Mulheres, jovens e crianças nos períodos de inundação. Conclusão: diante disso, os dados demonstraram que as enteroparasitoses acometem com frequência uma parcela da população local. Além de trazer informações que podem reforçar a necessidade da implementação do sistema de saneamento básico, juntamente com campanhas de conscientização populacional a respeito das vias de contaminação e da forma de propagação dessas infecções.


Introduction: intestinal parasites are diseases that present a worldwide health problem, causing major nutritional problems, where their occurrence varies according to the climate of each region and socioeconomic conditions. Regions that have tropical climates with humidity, high levels of rainfall and high temperatures associated with a lack of information on entero-parasitosis deserve attention. Objective: the present work sought to evaluate the types of intestinal parasites between the years 2018 to 2020 in a portion of the population of a municipality in the Western Amazon, more specifically, (i) to evaluate the types of entero-parasitosis that affect the population between periods of flooding and drought; (ii) to evaluate the influence of entero-parasitosis in individuals according to gender and age group over three years. Methodology: data collection was carried out between the years 2018 to 2020, through analysis of spreadsheets provided by the clinical analysis laboratory LABSUL. Results: 4236 stool exams were evaluated, of which only 1396 were positive for entero-parasitosis. Most of which were caused by protozoa (58.69%) that mainly affected women, young people and children during flood periods. Conclusion: in view of this, the data showed that intestinal parasites frequently affect a portion of the local population. In addition to bringing information that can reinforce the need to implement the basic sanitation system, together with population awareness campaigns regarding the routes of contamination and the way in which these infections spread.


Assuntos
Humanos , Masculino , Feminino , Criança , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Doenças Parasitárias , Parasitologia , Helmintíase , Estações do Ano , Estudos Transversais , Estudo Observacional
17.
J. pediatr. (Rio J.) ; 99(3): 302-308, May-June 2023. tab, graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1440469

RESUMO

Abstract Objective To analyze the follow-up, in specialized outpatient clinics, of infants reported with congenital syphilis during the penicillin shortage. Method A cross-sectional study was carried out in ten public maternity hospitals affiliated with the Brazilian Unified Health System in the city of Fortaleza, state of Ceará. Clinical records of infants reported with congenital syphilis who were born alive in 2015 were used to describe correlates of attendance at recommended clinical follow-up appointments. Results A total of 469 infants reported with CS from January 1/2015 to December 31/2015 were included in the analysis. The results show that most infants did not attend the follow-up visits (368/469, 78.5%) and the main associated factors are that the follow-up clinic is located in a different hospital from that where the infant was born (OR: 3.7; CI: 2.20-6.22; p< 0.001) and the use of illicit drugs by the mother (OR: 3.2; CI: 1.57-6.87; p= 0.002). Only 33.7% (34/101) were followed until discharge. Conclusion The majority of infants with reported congenital syphilis during this period did not attend the follow-up visits. Public health efforts aimed at reaching the parents of infants with CS should be a priority to ensure appropriate clinical identification and management of the associated outcomes of this vertically transmitted infection.

18.
Cien Saude Colet ; 28(5): 1491-1500, 2023 May.
Artigo em Português | MEDLINE | ID: mdl-37194881

RESUMO

The scope of this study was to understand the effects resulting from Integrative and Complementary Practices (ICPs) in the treatment of people with obesity cared for at a state center of reference of the Brazilian Unified Health System, based on the reports of users. Qualitative exploratory-descriptive methodology was used, employing semi-structured interviews as a technique for data production. The empirical universe was composed of eight male and female members in the adult age group, with a medical diagnosis of obesity and being monitored at the ICP Outpatient Clinic. Feeling well was observed as a significant and pivotal sensation for the ongoing experience in the ICPs, resulting from the therapy, materialized in the different effects produced by the practices and bringing about a reorganization of the subject's life, the care of oneself and of others. It was possible to observe that the organic presence of the ICPs assumes a hybrid and dynamic place in the process of care, although a perspective has emerged that links the ICPs to obesity through the control of anxiety, the body, and food. Furthermore, the ICPs seem to collaborate with the displacement of the focus of body weight management to the person as a whole, also acting as mediators in the process of body acceptance.


O estudo buscou compreender os efeitos produzidos pelo uso de Práticas Integrativas e Complementares no cuidado a pessoas com obesidade atendidas em um centro de referência estadual do Sistema Único de Saúde, a partir da narrativa dos usuários. Utilizou-se a metodologia qualitativa exploratório-descritiva, tendo como técnica de produção de dados as entrevistas semiestruturadas. O universo empírico foi composto por oito pessoas, dos gêneros masculino e feminino, na faixa etária adulta, com diagnóstico médico de obesidade e em acompanhamento no Ambulatório de PICS. Observou-se o sentir-se bem como sentimento marcante e definidor para a continuidade da vivência nas PICS, resultante da terapêutica, concretizado nos diferentes efeitos produzidos pelas práticas e articulador de uma reorganização da vida do sujeito, do cuidado de si e do outro. Foi possível observar que a presença orgânica das PICS assume um lugar híbrido e dinâmico no fluxo do cuidado, ainda que tenha se sobressaído uma perspectiva que vincula as PICS à obesidade por meio do controle da ansiedade, do corpo e da alimentação Além disso, as PICS parecem colaborar com o deslocamento da centralidade da gestão do peso corporal para a pessoa em sua integralidade, atuando ainda como mediadoras do processo de aceitação corporal.


Assuntos
Terapias Complementares , Emoções , Adulto , Humanos , Masculino , Feminino , Obesidade/terapia , Brasil
19.
Ciênc. Saúde Colet. (Impr.) ; 28(5): 1491-1500, maio 2023. tab
Artigo em Português | LILACS-Express | LILACS | ID: biblio-1439826

RESUMO

Resumo O estudo buscou compreender os efeitos produzidos pelo uso de Práticas Integrativas e Complementares no cuidado a pessoas com obesidade atendidas em um centro de referência estadual do Sistema Único de Saúde, a partir da narrativa dos usuários. Utilizou-se a metodologia qualitativa exploratório-descritiva, tendo como técnica de produção de dados as entrevistas semiestruturadas. O universo empírico foi composto por oito pessoas, dos gêneros masculino e feminino, na faixa etária adulta, com diagnóstico médico de obesidade e em acompanhamento no Ambulatório de PICS. Observou-se o sentir-se bem como sentimento marcante e definidor para a continuidade da vivência nas PICS, resultante da terapêutica, concretizado nos diferentes efeitos produzidos pelas práticas e articulador de uma reorganização da vida do sujeito, do cuidado de si e do outro. Foi possível observar que a presença orgânica das PICS assume um lugar híbrido e dinâmico no fluxo do cuidado, ainda que tenha se sobressaído uma perspectiva que vincula as PICS à obesidade por meio do controle da ansiedade, do corpo e da alimentação Além disso, as PICS parecem colaborar com o deslocamento da centralidade da gestão do peso corporal para a pessoa em sua integralidade, atuando ainda como mediadoras do processo de aceitação corporal.


Abstract The scope of this study was to understand the effects resulting from Integrative and Complementary Practices (ICPs) in the treatment of people with obesity cared for at a state center of reference of the Brazilian Unified Health System, based on the reports of users. Qualitative exploratory-descriptive methodology was used, employing semi-structured interviews as a technique for data production. The empirical universe was composed of eight male and female members in the adult age group, with a medical diagnosis of obesity and being monitored at the ICP Outpatient Clinic. Feeling well was observed as a significant and pivotal sensation for the ongoing experience in the ICPs, resulting from the therapy, materialized in the different effects produced by the practices and bringing about a reorganization of the subject's life, the care of oneself and of others. It was possible to observe that the organic presence of the ICPs assumes a hybrid and dynamic place in the process of care, although a perspective has emerged that links the ICPs to obesity through the control of anxiety, the body, and food. Furthermore, the ICPs seem to collaborate with the displacement of the focus of body weight management to the person as a whole, also acting as mediators in the process of body acceptance.

20.
J. pediatr. (Rio J.) ; 99(2): 193-202, Mar.-Apr. 2023. tab
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1430714

RESUMO

Abstract Objective: To investigate the association between emotional and behavioral difficulties in schoolchildren and maternal educational practices. Methods: Participants and Setting: 631 mother-child pairs were evaluated in a poor urban district in Recife, northeastern Brazil. Cross-sectional study carried out between 2013 and 2014. It integrates a prospective cohort study designed to investigate the consequences of intimate partner violence that occurred during pregnancy, postpartum, and seven years after birth for the physical and mental health of women and their children. Maternal educational practices were assessed using the Parent-Child Conflict Tactics Scale (CTSPC - mother-child version) and the child's behavioral and emotional disorders through the Strengths and Difficulties Questionnaire (SDQ) mother-version. The association was estimated through crude and adjusted prevalence ratios, using Poisson regression considering the 95% confidence interval. Results: The prevalence of violent maternal educational practices was 91.8% (572/631) being 89.7% (566/631) of psychological aggression and 75.6% of physical aggression, subdivided into corporal punishment (73.5%), physical maltreatment (35.8%) and severe physical maltreatment (1.7%). Corporal punishment (Adjusted PR 1.5; CI 95%: 1.1-2.1; p = 0.010) and severe physical maltreatment (Adjusted PR 1.9; CI 95%: 1.3-2.8; p = 0.002) were associated with emotional and behavioral difficulties in schoolchildren. Conclusion: The high prevalence of violent maternal educational practices, especially corporal punishment and severe physical maltreatment is associated with emotional and behavioral disorders in children. Therefore, it is necessary to interventions that promote parental support and effective use of non-violent discipline in conducting the educational process to establish healthier family relationships and to prevent/mitigate the impact of emotional and behavioral problems in children. © 2022 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. This is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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