[Effects of tumor necrosis factor on the tonus of cerebral arteries]. / Vliianie tumornekrotiziruiushchego faktora na tonus arterii golovnogo mozga.

It was determined that tumor necrosis factor (TNF) is capable of decreasing the local brain's blood flow on 45.6% (in the concentration of 6 micrograms/kg); to make a spasm of the pial arteries on 39.6%. In vitro experiments TNF increased the amplitude of the rhythmical and the tonic contractions of the brain's arteries smooth muscles (3.6 X 10(-8) M). The direct action of the TNF in the vascular wall is endothelium-dependent.

[Contractile function of the smooth muscle of the superficial arteries of the cerebral cortex]. / Sokratitel'naia funktsiia gladkikh myshts poverkhnostnykh arterii kory golovnogo mozga.

Cerebral vessel's muscle cells responses to biologically active substances and the metabolic factors were found to depend on the initial functional level of smooth muscles in segments of the cow pial artery.