1.
J Pediatr Hematol Oncol
; 46(5): e331-e333, 2024 07 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38652075
RESUMO
Multiple myeloma is a rare disease in pediatrics, where about 30 cases are described under 15 years old. It is even rarer when atypical multiple myeloma occurs in the context of autoimmunity. This case describes a 9-year-old female with autoimmune lymphoproliferative-like disease and combined immune deficiency that developed acute kidney failure with monoclonal peak associated with RAC2 and TNFRSF9 variants. An adapted protocol from the backbone adult multiple myeloma standard of care with the addition of an allogeneic hematopoietic stem cell transplant was used. The patient, now nearly a year posttransplant, shows 100% chimerism with no sign of relapse.
Assuntos
Transplante de Células-Tronco Hematopoéticas , Humanos , Feminino , Criança , Injúria Renal Aguda/etiologia , Injúria Renal Aguda/patologia , Mieloma Múltiplo/complicações , Mieloma Múltiplo/patologia , Síndrome Linfoproliferativa Autoimune/complicações , Síndrome Linfoproliferativa Autoimune/patologia , Síndrome Linfoproliferativa Autoimune/diagnóstico , Síndrome Linfoproliferativa Autoimune/genética
2.
Can J Public Health
; 114(4): 705-708, 2023 08.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37296368