RESUMO
Congenital abnormalities of the reproductive tract of male sheep were surveyed at three abattoirs in the south west of England during the period June 2000-January 2004. A total of 7307 rams were examined [6521 lambs (prepubescent) and hoggets (aged from their first autumn after birth until first shorn) and 786 adult rams mature rams that had been exposed to ewes]. A total of 156 congenital lesions were detected, 87 of which occurred in lambs. Testicular hypoplasia was the most common lesion occurring in 69 lambs as well as eight hoggets ('microtestes' were recognized in nine other animals in which the testis was disproportionately smaller than the epididymis). The second most common lesion found was notched scrotum occurring in 34 animals (27 young rams and seven adults). Some cases of notched scrotum were accompanied by hypospadias which was seen in a total of seven lambs and eight hoggets. Other lesions, detected in five or less animals (less than approximately 0.05% of the animals examined), included cryptorchidism and various abnormalities of the epididymis (segmental aplasia of the epididymis, blind efferent ducts and epididymal cyst) and congenital scrotal hernia. The overall prevalence of congenital lesions of 2.21% emphasizes the importance of undertaking breeding soundness examinations of young rams before they are put with the flock.
Assuntos
Genitália Masculina/anormalidades , Doenças dos Ovinos/epidemiologia , Ovinos/anormalidades , Matadouros , Animais , Criptorquidismo/epidemiologia , Criptorquidismo/veterinária , Inglaterra/epidemiologia , Epididimo/anormalidades , Hipospadia/epidemiologia , Hipospadia/veterinária , Masculino , Escroto/anormalidades , Maturidade Sexual , Doenças dos Ovinos/diagnóstico por imagem , Testículo/anormalidades , UltrassonografiaRESUMO
OBJECTIVES: The objectives of this study were to quantify the sensitivity and specificity of visual assessment of radiographs of the canine elbow in detecting ulnar trochlear notch sclerosis, to establish interobserver and intra-observer variation for the presence and grade of sclerosis and to quantify the effect of radiographic exposure on observer grading. METHODS: Mediolateral elbow radiographs were obtained from Labrador retrievers (n=34) aged between six and 18 months. Radiographs from dogs with an arthroscopic diagnosis of fragmented medial coronoid process (n=17) and those from a control population (n=17) were subjected to observer grading for the presence or absence of and the grade of ulnar trochlear notch sclerosis. Interobserver and intra-observer variation and observer sensitivity and specificity were calculated. Digital data from the ulnar trochlear notch were correlated with mean observer grade to quantify the effect of radiographic exposure on observer grade. RESULTS: Interobserver agreement was "fair" (kappa=0.251 to 0.369) and intra-observer agreement was "moderate" to "substantial" (kappa=0.462 to 0.667). The sensitivity of observer assessment was 72 per cent with a specificity of 22 per cent. Mean observer grade was not significantly correlated with the degree of radiographic exposure (P=0.70). CLINICAL SIGNIFICANCE: Ulnar trochlear notch sclerosis is a phenomenon associated with fragmented medial coronoid process. However, interobserver agreement in grading this feature is only fair, being identified by observers with moderate sensitivity but with relatively poor specificity. This low specificity may predispose to overdiagnosis in clinical cases. Intra-observer agreement is moderate to substantial, suggesting that individuals can reliably quantify this radiological feature on multiple occasions. The ability of observers to assess the degree of sclerotic change is not significantly affected by radiographic exposure.
Assuntos
Doenças do Cão/diagnóstico por imagem , Artropatias/veterinária , Ulna/patologia , Animais , Competência Clínica/estatística & dados numéricos , Doenças do Cão/patologia , Cães , Feminino , Artropatias/diagnóstico por imagem , Masculino , Variações Dependentes do Observador , Radiografia , Esclerose/diagnóstico por imagem , Esclerose/veterinária , Sensibilidade e Especificidade , Ulna/diagnóstico por imagem , Médicos Veterinários/normasRESUMO
OBJECTIVES: To evaluate the clinical, clinical pathology, diagnostic imaging, microbiological and pathological features of cholangitis/cholangiohepatitis in the dog. METHODS: The study design was a retrospective review of cases of bacterial cholangitis/cholangiohepatitis presented to the University of Bristol during the period 1995 to 2000. The diagnosis was made based on hepatic histopathological findings and positive bile culture results. RESULTS: Four dogs met the inclusion criteria. Common presenting signs included anorexia (n=4), jaundice (n=4), vomiting (n=4) and pyrexia (n=2). All four dogs had a leucocytosis or neutrophilia reported at some time in their history along with serum bilirubin elevation. In addition, serum alkaline phosphatase and alanine transaminase activity was increased in all of the dogs in which it was measured both before and at the time of referral. In general, the diagnostic imaging findings were non-specific. Organisms cultured from bile aspirates were Escherichia coli (n=3), Clostridium species (n=2) and a faecal Streptococcus species (n=1). Two cases resolved with medical treatment alone; two with concurrent cholecystitis required cholecystectomy. Following surgery, both of these cases showed a resolution of clinical signs. CLINICAL SIGNIFICANCE: This report highlights the fact that bacterial cholangitis/cholangiohepatitis with or without concurrent cholecystitis should be considered as a potential differential in dogs presenting with signs referable to biliary tract disease.
Assuntos
Infecções Bacterianas/veterinária , Colangite/veterinária , Colecistite/veterinária , Doenças do Cão/epidemiologia , Fosfatase Alcalina/sangue , Animais , Antibacterianos/administração & dosagem , Infecções Bacterianas/complicações , Infecções Bacterianas/epidemiologia , Bile/microbiologia , Bilirrubina/sangue , Análise Química do Sangue/veterinária , Colangite/complicações , Colangite/epidemiologia , Colecistectomia/veterinária , Colecistite/complicações , Colecistite/epidemiologia , Doenças do Cão/sangue , Doenças do Cão/diagnóstico , Doenças do Cão/diagnóstico por imagem , Doenças do Cão/microbiologia , Doenças do Cão/patologia , Doenças do Cão/terapia , Cães , Feminino , Irlanda/epidemiologia , Masculino , Prontuários Médicos , Estudos Retrospectivos , UltrassonografiaRESUMO
REASONS FOR PERFORMING STUDY: Tearing of the medial palmar intercarpal ligament (MPICL) has been recognised as a cause of lameness in the Thoroughbred, but diagnosis is difficult due to the nonspecific clinical signs, and can be achieved only by performing arthroscopy on the mid carpal joint (MCJ). It would be beneficial to be able to image the MPICL using ultrasonography to determine whether pathology is present in the ligament in order to aid diagnosis and prognosis. OBJECTIVES: To determine whether the MPICL could be imaged using ultrasound from the dorsal aspect of the MCJ, and to describe the technique and normal ultrasonographic appearance of the ligament. METHODS: A pilot study was performed using 2 cadaver carpi. Each carpus in turn had the MPICL imaged simultaneously using arthroscopy and ultrasound, with a metallic probe positioned on the dorsal aspect of the ligament to highlight the position of the MPICL. Six further pairs of carpi had the MPICL imaged ultrasonographically followed by dissection of the carpus to evaluate the ligament and relate its anatomy to the ultrasound images. Finally, 15 Thoroughbreds with no history of lameness isolated to the carpus had their MPICLs assessed and measured ultrasonographically. RESULTS: The MPICL could be imaged via the dorsal aspect of the MCJ using standard ultrasound equipment. The body and division into medial and lateral branches could be seen as a distinct, moderately dense granular echogenic structure in the palmar aspect of the joint, with clearly defined margins. CONCLUSIONS: The normal MPICL can be imaged reliably using ultrasound in the Thoroughbred from the dorsal aspect of the MCJ. There is a wide range in the normal width of the lateral aspect of the MPICL, but there is good symmetry between contralateral limbs. POTENTIAL RELEVANCE: This report of the normal ultrasonographic appearance of the ligament will be beneficial in acting as a reference for the detection of pathology using ultrasound.
Assuntos
Carpo Animal/diagnóstico por imagem , Cavalos/anatomia & histologia , Coxeadura Animal/diagnóstico por imagem , Ligamentos/diagnóstico por imagem , Animais , Artroscopia/veterinária , Cadáver , Carpo Animal/anatomia & histologia , Diagnóstico Diferencial , Feminino , Coxeadura Animal/diagnóstico , Ligamentos/anatomia & histologia , Masculino , Projetos Piloto , Prognóstico , Valores de Referência , UltrassonografiaRESUMO
Three dogs were presented for investigation of recurrent pyrexia of unknown origin, chronic vomiting and respiratory distress, respectively. One dog was markedly underweight and the other two were cachexic. Physical examination and initial diagnostic tests failed to establish the underlying cause of the presenting signs. Thoracic radiographs were within normal limits for the age of the dog. In each case there was a high index of suspicion for an occult neoplastic process in view of the profound unexplained weight loss present. High-resolution computed tomography (HRCT) of the thorax was performed. The lung fields were divided into three zones for analysis and a novel classification scheme was used to describe the HRCT findings in each zone. Postmortem examination and histopathology confirmed the presence of an infiltrating metastatic carcinoma in all three cases. The HRCT changes correlated closely with the pathological findings. The authors conclude that HRCT of the lung should be considered for pulmonary metastatic screening in the dog and introduce a classification system for HRCT findings, based on terminology used in human medicine.
Assuntos
Doenças do Cão/diagnóstico por imagem , Neoplasias Pulmonares/veterinária , Tomografia Computadorizada por Raios X/veterinária , Neoplasias das Glândulas Suprarrenais/complicações , Neoplasias das Glândulas Suprarrenais/diagnóstico por imagem , Neoplasias das Glândulas Suprarrenais/patologia , Neoplasias das Glândulas Suprarrenais/veterinária , Animais , Carcinoma/complicações , Carcinoma/diagnóstico por imagem , Carcinoma/secundário , Carcinoma/veterinária , Estudos de Casos e Controles , Doenças do Cão/patologia , Cães , Feminino , Febre/etiologia , Febre/veterinária , Neoplasias Pulmonares/complicações , Neoplasias Pulmonares/diagnóstico por imagem , Neoplasias Pulmonares/secundário , Masculino , Neoplasias Primárias Desconhecidas/complicações , Neoplasias Primárias Desconhecidas/diagnóstico por imagem , Neoplasias Primárias Desconhecidas/veterinária , Insuficiência Respiratória/etiologia , Insuficiência Respiratória/veterináriaRESUMO
With the rapid spread of human immunodeficiency virus (HIV) infection worldwide it is clear that effective strategies for mucosal vaccination against lentiviruses are urgently required. The aim of the present study is to determine whether protective immune responses against a mucosal challenge by feline immunodeficiency virus (FIV) can be elicited by targeting the immunization to the medial iliac lymph nodes--the principal site of migration of cells from the genital and rectal mucosa. Cats were challenged with homologous FIV via the rectal route. Targeted lymph node immunization was found to be an effective route of immunization eliciting both humoral and proliferative responses to peptide-based and fixed cell vaccines. Vaccination with fixed virus infected cells elicited protection against a cell-free mucosal FIV challenge. In addition, some cats vaccinated with fixed uninfected cells also remained uninfected following a cell-associated FIV challenge.
Assuntos
Antígenos Virais/administração & dosagem , Síndrome de Imunodeficiência Adquirida Felina/prevenção & controle , Glicoproteínas/administração & dosagem , Vírus da Imunodeficiência Felina/imunologia , Linfonodos/imunologia , Vacinação/veterinária , Proteínas do Envelope Viral/administração & dosagem , Vacinas Virais/administração & dosagem , Administração Retal , Sequência de Aminoácidos , Animais , Anticorpos Antivirais/biossíntese , Anticorpos Antivirais/imunologia , Antígenos Virais/química , Antígenos Virais/imunologia , Gatos , Células Cultivadas/transplante , Células Cultivadas/virologia , Avaliação de Medicamentos , Síndrome de Imunodeficiência Adquirida Felina/imunologia , Produtos do Gene gag/imunologia , Glicoproteínas/química , Glicoproteínas/imunologia , Vírus da Imunodeficiência Felina/fisiologia , Injeções Intralinfáticas , Dados de Sequência Molecular , Fragmentos de Peptídeos/administração & dosagem , Fragmentos de Peptídeos/química , Fragmentos de Peptídeos/imunologia , Projetos Piloto , Linfócitos T/transplante , Linfócitos T/virologia , Vacinação/métodos , Vacinas de Subunidades Antigênicas/administração & dosagem , Vacinas de Subunidades Antigênicas/imunologia , Vacinas Sintéticas/administração & dosagem , Vacinas Sintéticas/imunologia , Proteínas do Envelope Viral/química , Proteínas do Envelope Viral/imunologia , Vacinas Virais/imunologiaRESUMO
The superficial supramammary lymph nodes of 54 lactating dairy cows were examined ultrasonographically with a 7.5 MHz linear transducer; each node was measured in two planes within 24 hours of recording the milk somatic cell count. In most cows, the nodes were well demarcated from the surrounding tissue. The parenchyma of the nodes ranged from hypoechoic to anechoic, with a central bright hyperechoic area, and a thin hyperechoic line surrounded the nodes. The size of the nodes varied, but their internal architecture remained relatively consistent. Their mean length was 7.4 cm (range 3.5 to 15 cm) and their mean depth was 2.5 cm (range 1.2 to 5.7 cm). They were significantly larger in cows with more lactations (P<0.05), but there were no correlations between their size and either the time calved or the milk somatic cell count. The lymph nodes on sides which were positive in a California milk test were significantly larger than those on sides which were negative (P<0.05).
Assuntos
Linfonodos/diagnóstico por imagem , Mastite/diagnóstico por imagem , Animais , Bovinos , Feminino , Linfonodos/anatomia & histologia , Glândulas Mamárias Animais , UltrassonografiaRESUMO
The purpose of this study was to determine the accuracy of transabdominal ultrasound in estimating the volume and weight of the canine prostate gland, to derive a simple formula from actual and ultrasonographic prostate measurements for estimating prostate volume and weight, and to evaluate the reproducibility of ultrasonographic measurements of linear prostate dimensions. The prostate volume and weight were measured and also calculated in 77 male canine cadavers (60 entire and 17 neutered) with the aid of statistical computer programmes using actual linear dimensions of the prostate ('actual') and those measured ultrasonographically before ('in vivo') and after ('in vitro') removal of the prostate gland. Therefore, 'in vivo', 'in vitro' and 'actual' estimations of prostate size were obtained and compared with prostatic volume and weight. The evaluation of the reproducibility of the ultrasonographic measurements made was performed in 59 of the dogs in which the prostate was imaged three times in longitudinal and three times in transverse sections. This study demonstrated that prostatic weight and volume are related to body weight and age in entire dogs but not in neutered dogs. Formulae were derived to estimate prostate weight and volume from physical and ultrasonographic measurements. There were good correlations between the ultrasonographic and physical measurements and prostate size derived from these measurements provided a good estimate of actual prostate size. 'Best subsets' analyses indicated that prostate width and length (measured physically or ultrasonographically) were the best predictors of prostatic volume and weight, both when all dogs were considered together and in entire dogs only. Statistical analyses indicated that there were no significant differences between the repeated measurements of length and depth (P>0.05). However, there was a significant difference between repeated measurements of width (P= 0.0357).
Assuntos
Cães/anatomia & histologia , Próstata/diagnóstico por imagem , Animais , Masculino , Hiperplasia Prostática/diagnóstico por imagem , Hiperplasia Prostática/veterinária , Neoplasias da Próstata/diagnóstico por imagem , Neoplasias da Próstata/veterinária , Prostatite/diagnóstico por imagem , Prostatite/veterinária , Reprodutibilidade dos Testes , UltrassonografiaRESUMO
A cystic thymoma was identified in an eight-year-old domestic longhair cat with a chronic cough. Radiographs indicated a large mass of soft tissue density in the anterior thorax. Ultrasonography revealed an echogenic mass occupying the cranial and mid-thorax with a slight swirling movement of the echoes. Subsequent drainage under ultrasound guidance yielded a cholesterol-rich fluid. The mass was resected at exploratory thoracotomy and the diagnosis of thymoma confirmed. There was no sign of recurrence one year postoperatively. The clinical features and unusual laboratory findings are presented and compared with previously reported cases of thymomata in the cat.
Assuntos
Doenças do Gato/diagnóstico , Colesterol/análise , Cistos/veterinária , Timoma/veterinária , Neoplasias do Timo/veterinária , Animais , Doenças do Gato/diagnóstico por imagem , Gatos , Cistos/química , Cistos/diagnóstico por imagem , Masculino , Timoma/química , Timoma/diagnóstico por imagem , Neoplasias do Timo/química , Neoplasias do Timo/diagnóstico por imagem , UltrassonografiaRESUMO
This report describes the presenting features, radiographic changes, biochemical alterations and clinical progress of two kittens, from separate litters, which were found to have a growth plate disturbance initially diagnosed and treated as vitamin D3-dependent rickets, but subsequently suspected to be a metaphyseal chondrodysplasia.
Assuntos
Doenças do Gato/diagnóstico , Osteocondrodisplasias/veterinária , Animais , Cálcio/sangue , Doenças do Gato/sangue , Doenças do Gato/patologia , Gatos , Diagnóstico Diferencial , Feminino , Membro Anterior/diagnóstico por imagem , Membro Anterior/patologia , Lâmina de Crescimento/patologia , Membro Posterior/diagnóstico por imagem , Membro Posterior/patologia , Masculino , Osteocondrodisplasias/diagnóstico , Osteocondrodisplasias/patologia , Fósforo/sangue , Radiografia , Raquitismo/diagnóstico , Raquitismo/patologia , Raquitismo/veterináriaRESUMO
A three-month-old native pony foal had a history of recurrent episodes of bizarre neurological behaviour. The results of clinical examinations were non-specific but clinicopathological investigations indicated hepatic encephalopathy. A percutaneous, needle liver biopsy revealed histopathological changes consistent with a portosystemic shunt, which was later identified by operative mesenteric portovenography, and confirmed at post mortem.