Stress symptoms occur in patients undergoing chemotherapy treatment independently of the level of physical activity.

The cancer patient is undergoing a set of procedures that affect the physical and psychological balance, which can generate stressful situations in the organism. In turn, physical activity helps to treat stress, promoting well-being and reducing anxiety. Our study aimed to verify the influence of physical activity practice on stress symptoms in patients undergoing oncological chemotherapy treatment. For this, we used Lipp's Inventory of Stress Symptoms (ISSL) and the International Physical Activity Questionnaire (IPAQ) in 56 patients with cancer. Our data show that 45.4% of the participants exhibited stress scores, of which, 21.8% were at near to exhaustion, and 23.6% at exhaustion. We observed that 30% of them are considered sufficiently active, 25% insufficiently active, 45% sedentary. No association was observed between physical activity and stress. These findings indicate that stress symptoms occur in patients undergoing chemotherapy treatment regardless of the level of physical activity.

Polar Lipids of Marine Microalgae Nannochloropsis oceanica and Chlorococcum amblystomatis Mitigate the LPS-Induced Pro-Inflammatory Response in Macrophages.

Microalgae are recognized as a relevant source of bioactive compounds. Among these bioactive products, lipids, mainly glycolipids, have been shown to present immunomodulatory properties with the potential to mitigate chronic inflammation. This study aimed to evaluate the anti-inflammatory effect of polar lipids isolated from Nannochloropsis oceanica and Chlorococcum amblystomatis. Three fractions enriched in (1) digalactosyldiacylglycerol (DGDG) and sulfoquinovosyldiacylglycerol (SQDG), (2) monogalactosyldiacylglycerol (MGDG), and (3) diacylglyceryl-trimethylhomoserine (DGTS) and phospholipids (PL) were obtained from the total lipid extracts (TE) of N. oceanica and C. amblystomatis, and their anti-inflammatory effect was assessed by analyzing their capacity to counteract nitric oxide (NO) production and transcription of pro-inflammatory genes Nos2, Ptgs2, Tnfa, and Il1b in lipopolysaccharide (LPS)-activated macrophages. For both microalgae, TE and Fractions 1 and 3 strongly inhibited NO production, although to different extents. A strong reduction in the LPS-induced transcription of Nos2, Ptgs2, Tnfa, and Il1b was observed for N. oceanica and C. amblystomatis lipids. The most active fractions were the DGTS-and-PL-enriched fraction from N. oceanica and the DGDG-and-SQDG-enriched fraction from C. amblystomatis. Our results reveal that microalgae lipids have strong anti-inflammatory capacity and may be explored as functional ingredients or nutraceuticals, offering a natural solution to tackle chronic inflammation-associated diseases.

Prevenção do câncer de mama na Atenção Primária à Saúde: uma análise sobre a atuação de enfermeiros / Breast cancer prevention in Primary Health Care: an analysis on the performance of nurses

O câncer de mama (CM) é o tumor maligno que mais mata mulheres no mundo, sendo considerado um grave problema de saúde pública. Este artigo investiga as ações de enfermeiros atuantes na Atenção Primária à Saúde na prevenção do CM em Campina Grande-PB. Trata-se de um estudo descritivo-exploratório, de abordagem qualitativa, realizado com 10 enfermeiros que atuam em unidades básicas de saúde do referido município, por meio de entrevista semiestruturada. Os dados coletados foram analisados por meio da análise de conteúdo, com o auxílio do software Atlas.ti. Em seus resultados emergiram cinco categorias: Conhecimentos gerais sobre CM; Capacitação profissional e educação em saúde da população; Abordagem clínica do enfermeiro na prevenção do CM; Dificuldades na prevenção; Autoanálise da prática profissional. Entre estas, destacou-se a influência negativa da falta de capacitações para ajustamento das ações dos enfermeiros às diretrizes nacionais de prevenção do CM na Atenção Primária à Saúde.

Breast cancer is the malignant tumor that kills the most women worldwide, being considered a serious public health problem. This article investigates the actions of nurses working in Primary Health Care in the prevention of breast cancer in Campina Grande-PB. This is a descriptive-exploratory study, with a qualitative approach, carried out with 10 nurses who work in basic health units in that city, through semi-structured interviews. The collected data were analyzed through content analysis, with the help of the Atlas.ti software. Five categories emerged from their results: General knowledge about breast cancer; Professional training and health education for the population; Nurses' clinical approach to breast cancer prevention; Difficulties in prevention; Self-analysis of professional practice. Among these, the negative influence of the lack of training to adjust the nurses' actions to the national guidelines for the prevention of breast cancer in Primary Health Care was highlighted.

Transcriptional, epigenetic and metabolic signatures in cardiometabolic syndrome defined by extreme phenotypes.

BACKGROUND: This work is aimed at improving the understanding of cardiometabolic syndrome pathophysiology and its relationship with thrombosis by generating a multi-omic disease signature. METHODS/RESULTS: We combined classic plasma biochemistry and plasma biomarkers with the transcriptional and epigenetic characterisation of cell types involved in thrombosis, obtained from two extreme phenotype groups (morbidly obese and lipodystrophy) and lean individuals to identify the molecular mechanisms at play, highlighting patterns of abnormal activation in innate immune phagocytic cells. Our analyses showed that extreme phenotype groups could be distinguished from lean individuals, and from each other, across all data layers. The characterisation of the same obese group, 6 months after bariatric surgery, revealed the loss of the abnormal activation of innate immune cells previously observed. However, rather than reverting to the gene expression landscape of lean individuals, this occurred via the establishment of novel gene expression landscapes. NETosis and its control mechanisms emerge amongst the pathways that show an improvement after surgical intervention. CONCLUSIONS: We showed that the morbidly obese and lipodystrophy groups, despite some differences, shared a common cardiometabolic syndrome signature. We also showed that this could be used to discriminate, amongst the normal population, those individuals with a higher likelihood of presenting with the disease, even when not displaying the classic features.

G protein-coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1.

The interindividual variation in the functional response of platelets to activation by agonists is heritable. Genome-wide association studies (GWASs) of quantitative measures of platelet function have identified fewer than 20 distinctly associated variants, some with unknown mechanisms. Here, we report GWASs of pathway-specific functional responses to agonism by adenosine 5'-diphosphate, a glycoprotein VI-specific collagen mimetic, and thrombin receptor-agonist peptides, each specific to 1 of the G protein-coupled receptors PAR-1 and PAR-4, in subsets of 1562 individuals. We identified an association (P = 2.75 × 10-40) between a common intronic variant, rs10886430, in the G protein-coupled receptor kinase 5 gene (GRK5) and the sensitivity of platelets to activate through PAR-1. The variant resides in a megakaryocyte-specific enhancer that is bound by the transcription factors GATA1 and MEIS1. The minor allele (G) is associated with fewer GRK5 transcripts in platelets and the greater sensitivity of platelets to activate through PAR-1. We show that thrombin-mediated activation of human platelets causes binding of GRK5 to PAR-1 and that deletion of the mouse homolog Grk5 enhances thrombin-induced platelet activation sensitivity and increases platelet accumulation at the site of vascular injury. This corroborates evidence that the human G allele of rs10886430 is associated with a greater risk for cardiovascular disease. In summary, by combining the results of pathway-specific GWASs and expression quantitative trait locus studies in humans with the results from platelet function studies in Grk5-/- mice, we obtain evidence that GRK5 regulates the human platelet response to thrombin via the PAR-1 pathway.

Abdominal tuberculosis: an old disease surprising young doctors.

Tuberculosis remains a worldwide public health concern. Atypical extrapulmonary presentations may delay the diagnosis and treatment. We present the case of an adult woman admitted to the emergency department with bowel obstruction. The putative intraoperative diagnostic hypothesis was ovarian cancer with peritoneal dissemination. Histopathological analysis showed a chronic granulomatous inflammatory disease with acid-fast bacilli. The patient was started on an alternative parenteral antituberculosis drug combination until oral feeding was available. Currently, 5 months after surgery, she is asymptomatic. Abdominal tuberculosis is the most frequent extrapulmonary site with a wide range of clinical presentations. Emergency laparotomy may be necessary in patients who present with acute abdomen. Bowel obstruction due to adhesions and strictures is not infrequent. However, tuberculous abdominal cocoon presentation as in our patient is rare. Treatment with parenteral alternative drug regimens for tuberculosis is mandatory until the oral route is available.

Adult Acne: Prevalence and Portrayal in Primary Healthcare Patients, in the Greater Porto Area, Portugal.

INTRODUCTION: Though typically found in adolescents, acne frequently affects the adult population. In Portugal, no representative studies about acne prevalence in greater populational areas are known. This study had the following objectives: calculate acne prevalence in primary healthcare patients; its characteristics, including risk factors for onset and worsening; collect information concerning selfmedication and/or prescribed treatment. MATERIAL AND METHODS: Application of a questionnaire and physical examination into a convenience sample, composed by adults from20 - 60 years old that visited, in random days, five primary healthcare centers of the Greater Porto area. RESULTS: From the 1,055 evaluated adults, acne prevalence was estimated at 61.5%. Only 36.8% of acne suffering adults was awareof their condition. More than half of tobacco users (62.3%) had acne. Just 25% of acne sufferers sought treatment. The most affected areas were the malars, differing from the younger disease form. DISCUSSION: Acne prevalence was relatively higher than other studies. The results of this study have confirmed that acne seems to be related with increased calorie intake, tobacco smoking, whole milk and fat-reduced milk consumption, hirsutism, alopecia and seborrhea. CONCLUSION: In the primary healthcare set, more than half of adults were acne sufferers. These numbers show how important primary healthcare services can be in preventing and intervening when managing acne-related risk factors and psychosocial consequences.

Introdução: A acne, apesar de caraterística no adolescente, afeta frequentemente o adulto. Em Portugal, não são conhecidos estudos sobre a prevalência da acne no adulto, nomeadamente observada nos grandes centros populacionais. Os objetivos deste estudo foram estimar a prevalência da acne nos utentes dos serviços de cuidados de saúde primários, as suas características, incluindo fatores de risco para início e/ou agravamento, além de coletar informação relacionada com a automedicação e/ou tratamento prescrito. Material e Métodos: Aplicação de questionário e exame físico a amostra composta por adultos entre os 20 - 60 anos de idade que visitaram, em dias aleatórios, cinco centros de saúde da área do Grande Porto. Resultados: Dos 1 055 adultos avaliados, a prevalência estimada de acne foi de 61,5%. Apenas 36,8% dos portadores estavam cientes da sua condição e somente 25% afirmou ter procurado tratamento. Mais de metade dos fumadores (62,3%) apresentavam acne. A zona mais afetada foi a região malar, diferindo da forma adolescente da doença. Discussão: A prevalência encontrada de acne foi mais elevada do que em outros estudos. A acne aparentou estar relacionada com a ingestão calórica aumentada, tabagismo, consumo de leite gordo ou meio gordo, hirsutismo, alopécia e seborreia. Conclusão: No contexto dos cuidados de saúde primários, mais de metade dos adultos eram portadores de acne. Estes números demonstram o quão importante pode ser a prevenção e intervenção pelos profissionais dos cuidados de saúde primários, tanto para a redução de eventuais factores de risco como para a intervenção terapêutica e consequências psicossociais relacionadas com a acne. Palavras-chave: Acne Vulgaris/epidemiologia; Adulto; Cuidados de Saúde Primários; Portugal; Prevalência.

A content validity study of signs, symptoms and diseases/health problems expressed in LIBRAS / Um estudo da validade de conteúdo de sinais, sintomas e doenças/agravos em saúde expressos em LIBRAS / Estudio de la validez de contenido de señales, síntomas y enfermedades/daños de la salud expresados en LIBRAS

Objectives: to validate the content of signs, symptoms and diseases/health problems expressed in LIBRAS for people with deafness Method: methodological development study, which involved 36 people with deafness and three LIBRAS specialists. The study was conducted in three stages: investigation of the signs, symptoms and diseases/health problems, referred to by people with deafness, reported in a questionnaire; video recordings of how people with deafness express, through LIBRA, the signs, symptoms and diseases/health problems; and validation of the contents of the recordings of the expressions by LIBRAS specialists. Data were processed in a spreadsheet and analyzed using univariate tables, with absolute frequencies and percentages. The validation results were analyzed using the Content Validity Index (CVI). Results: 33 expressions in LIBRAS, of signs, symptoms and diseases/health problems were evaluated, and 28 expressions obtained a satisfactory CVI (1.00). Conclusions: the signs, symptoms and diseases/health problems expressed in LIBRAS presented validity, in the study region, for health professionals, especially nurses, for use in the clinical anamnesis of the nursing consultation for people with deafness.

Objetivo: validar o conteúdo de sinais, sintomas e doenças/agravos em saúde expressos em LIBRAS por pessoas com surdez. Método: estudo de desenvolvimento metodológico, no qual participaram 36 pessoas com surdez e três especialistas em LIBRAS. O estudo foi desenvolvido em três etapas: investigação dos sinais, sintomas e doenças/agravos em saúde, referidos pelas pessoas com surdez, assinalados em um questionário; registros em vídeo sobre como as pessoas com surdez expressam-se por meio da LIBRAS, os sinais, sintomas e doenças/agravos em saúde; e validação do conteúdo dos registros das expressões por especialistas em LIBRAS. Os dados foram processados em planilha eletrônica e analisados por meio de tabelas univariadas, com frequências absolutas e porcentagens. Os resultados da validação foram analisados através do Índice de Validade de Conteúdo (IVC). Resultados: avaliaram-se 33 expressões em LIBRAS, de sinais, sintomas e doenças/agravos em saúde, e 28 expressões obtiveram IVC satisfatório (1,00). Conclusões: os sinais, sintomas e doenças/agravos em saúde expressos em LIBRAS apresentam validade, na região do estudo, para profissionais de saúde, em especial o enfermeiro, para utilização na anamnese clínica da consulta de enfermagem à pessoa com surdez.

Objetivo: validar el contenido de señales, síntomas y enfermedades/daños de la salud expresados en LIBRAS por personas con sordera. Método: estudio de desarrollo metodológico, en el cual participaron 36 personas con sordera y tres especialistas en LIBRAS. El estudio fue desarrollado en tres etapas: investigación de las señales, síntomas y enfermedades/daños de la salud referidos por las personas con sordera, señalados en un cuestionario; registro en video sobre cómo las personas con sordera se expresan por medio de LIBRAS, las señales, síntomas y enfermedades/daños de la salud; y validación del contenido de los registros de las expresiones por especialistas en LIBRAS. Los datos fueron procesados en planilla electrónica y analizados por medio de tablas univariadas, con frecuencias absolutas y porcentajes. Los resultados de la validación fueron analizados a través del Índice de Validez de Contenido (IVC). Resultados: se evaluaron 33 expresiones de LIBRAS, de señales, síntomas y enfermedades/daños de la salud; 28 expresiones obtuvieron IVC satisfactorio (1,00). Conclusiones: las señales, los síntomas y las enfermedades/daños de la salud expresados en LIBRAS presentaron validez, en la región del estudio, para profesionales de la salud, en especial para enfermeros, que la pueden utilizar en la anamnesis clínica de consultas de enfermería en personas con sordera.

Fatores associados à notificação da sífilis congênita: um indicadorde qualidade da assistência pré-natal / Factors associated to the notification of congenital syphilis: an indicator of quality of prenatal care

Analisar fatores associados à notificação da sífilis congênita. Métodos: estudo transversal, documental, quantitativo, realizado através do Sistema Nacional de Agravos de Notificação. Compuseram o estudo 113 casos notificados. Utilizou-se formulário para coleta de dados e efetuaram-se os testes Qui-quadrado e Fisher. Resultados: mulheres realizaram pré-natal (80,2%), teste sorológico antes dos seis meses de gestação (46,7%) e após (53,3%). Houve associação para as variáveis raça (p=0,005) e realização do teste sorológico (p=0,044). Tratamento da gestante foi inadequado (64,5%) e o parceiro não foi tratado (85,7%). Conclusão: constatou-se que é crescente o número de casos, aumentando a possibilidade de crianças com sequelas graves. Por isso ainda é preciso melhorias na assistência pré-natal...

Mondor's disease in puerperium: case report.

Mondor's disease is a rare entity characterized by sclerosing thrombophlebitis classically involving one or more of the subcutaneous veins of the breast and anterior chest wall. It is usually a self-limited, benign condition, despite of rare cases of association to cancer. We present the case of a 32 year-old female, breast-feeding, who went to emergency due to left mastalgia for the past week. She was taking antibiotics and non-steroidal anti-inflammatory drugs, previously prescribed for suspicious of mastitis, for three days, with no clinical improvement. Physical examination showed an enlarged left breast, an axillary lump and a painful cord-like structure in the upper outer quadrant of the same breast. Ultrasound scan showed a markedly dilated superficial vein in the upper outer quadrant of left breast. The patient was given a ventropic therapy and was kept in anti-inflammatory, with progressive pain improvement. Ultrasound control was performed after four weeks, showing reperfusion.

Mondor's disease in puerperium: case report / Doença de Mondor no puerpério: caso clínico

Mondor's disease is a rare entity characterized by sclerosing thrombophlebitis classically involving one or more of the subcutaneous veins of the breast and anterior chest wall. It is usually a self-limited, benign condition, despite of rare cases of association to cancer. We present the case of a 32 year-old female, breast-feeding, who went to emergency due to left mastalgia for the past week. She was taking antibiotics and non-steroidal anti-inflammatory drugs, previously prescribed for suspicious of mastitis, for three days, with no clinical improvement. Physical examination showed an enlarged left breast, an axillary lump and a painful cord-like structure in the upper outer quadrant of the same breast. Ultrasound scan showed a markedly dilated superficial vein in the upper outer quadrant of left breast. The patient was given a ventropic therapy and was kept in anti-inflammatory, with progressive pain improvement. Ultrasound control was performed after four weeks, showing reperfusion.

A doença de Mondor é entidade rara caracterizada por tromboflebite esclerosante envolvendo classicamente uma ou mais das veias subcutâneas da mama e da parede torácica anterior. Trata-se de condição benigna normalmente auto-limitada, apesar de raros casos de associação ao câncer. Descreve-se o caso de uma mulher lactante de 32 anos de idade, que procurou serviço de emergência devido a mastalgia do lado direito na última semana. A paciente estava tomando antibióticos, mas não medicamentos esteroides anti-inflamatórios, previamente prescritos devido a suspeita de mastite, nos últimos três dias, sem melhora clínica. O exame físico mostrou o seio esquerdo aumentado, um nódulo axilar e uma estrutura dolorosa em formato de corda no quadrante superior externo da mesma mama. A ultrassonografia revelou uma veia superficial acentuadamente dilatada no quadrante superior externo da mama esquerda. A paciente recebeu terapia venotrópica and manteve o tratamento com anti-inflamatórios, com melhora progressiva da dor. Controle ultrassonográfico foi realizado após quatro semana, mostrando reperfusão.

A novel model of distal colon cancer in athymic mice.

PURPOSE: The present a novel adenocarcinoma model in athymic mice. METHODS: Seven athymic mice were used. Colon diversion and distal fistula were made. Adenocarcinoma cells were inoculated in the submucosa of fistula. Tumor growth was monitored daily. Scintigraphy with 99mTc-MIBI was performed to identify the tumor. RESULTS: The model of distal colon cancer is feasible. Tumor detection was possible by both, macroscopically and molecular imaging. All resections demonstrated poorly differentiated tumors. Colon obstruction occurred in one case, similarly to evolution in human tumors of distal colon. CONCLUSION: The proposed model of distal colon cancer is feasible, allows for easy monitoring of tumoral growth by both, macroscopically and molecular imaging, and is suitable for studying the evolution of tumor with implementation of cytotoxic therapy in vivo.

A novel model of distal colon cancer in athymic mice / Novo modelo de câncer de cólon distal em camundongos atímicos

PURPOSE: The present a novel adenocarcinoma model in athymic mice. METHODS: Seven athymic mice were used. Colon diversion and distal fistula were made. Adenocarcinoma cells were inoculated in the submucosa of fistula. Tumor growth was monitored daily. Scintigraphy with 99mTc-MIBI was performed to identify the tumor. RESULTS: The model of distal colon cancer is feasible. Tumor detection was possible by both, macroscopically and molecular imaging. All resections demonstrated poorly differentiated tumors. Colon obstruction occurred in one case, similarly to evolution in human tumors of distal colon. CONCLUSION: The proposed model of distal colon cancer is feasible, allows for easy monitoring of tumoral growth by both, macroscopically and molecular imaging, and is suitable for studying the evolution of tumor with implementation of cytotoxic therapy in vivo.

OBJETIVO: Apresentar novo modelo de adenocarcinoma distal em camundongos atímicos. MÉTODOS: Foram utilizados sete camundongos atímicos. Desvio do cólon distal e fístula foram feitas. Células de adenocarcinoma foram inoculadas na submucosa da fístula. O crescimento do tumor foi monitorado diariamente. Cintilografia com 99mTc-MIBI foi realizada para identificar o tumor. RESULTADOS: O modelo de câncer de cólon distal é viável. Detecção do tumor foi possível macroscopicamente e por imagem molecular. Todas as ressecções demonstraram tumores pouco diferenciados. Obstrução do cólon ocorreu em um caso, de forma semelhante à evolução em tumores humanos do cólon distal. CONCLUSÃO: O modelo de câncer do cólon distal proposto é viável, permite a monitorização fácil do crescimento tumoral macroscopicamente e por imagem molecular, sendo adequado para o estudo da evolução de tumor com aplicação de terapia citotóxica in vivo.

Degeneration of penicillin production in ethanol-limited chemostat cultivations of Penicillium chrysogenum: A systems biology approach.

BACKGROUND: In microbial production of non-catabolic products such as antibiotics a loss of production capacity upon long-term cultivation (for example chemostat), a phenomenon called strain degeneration, is often observed. In this study a systems biology approach, monitoring changes from gene to produced flux, was used to study degeneration of penicillin production in a high producing Penicillium chrysogenum strain during prolonged ethanol-limited chemostat cultivations. RESULTS: During these cultivations, the biomass specific penicillin production rate decreased more than 10-fold in less than 22 generations. No evidence was obtained for a decrease of the copy number of the penicillin gene cluster, nor a significant down regulation of the expression of the penicillin biosynthesis genes. However, a strong down regulation of the biosynthesis pathway of cysteine, one of the precursors of penicillin, was observed. Furthermore the protein levels of the penicillin pathway enzymes L-α-(δ-aminoadipyl)-L-α-cystenyl-D-α-valine synthetase (ACVS) and isopenicillin-N synthase (IPNS), decreased significantly. Re-cultivation of fully degenerated cells in unlimited batch culture and subsequent C-limited chemostats did only result in a slight recovery of penicillin production. CONCLUSIONS: Our findings indicate that the observed degeneration is attributed to a significant decrease of the levels of the first two enzymes of the penicillin biosynthesis pathway, ACVS and IPNS. This decrease is not caused by genetic instability of the penicillin amplicon, neither by down regulation of the penicillin biosynthesis pathway. Furthermore no indications were obtained for degradation of these enzymes as a result of autophagy. Possible causes for the decreased enzyme levels could be a decrease of the translation efficiency of ACVS and IPNS during degeneration, or the presence of a culture variant impaired in the biosynthesis of functional proteins of these enzymes, which outcompeted the high producing part of the population.

Baetidae (insecta: ephemeroptera) de nova xavantina, Mato Grosso, Brasil: novos registros e descrição de uma nova espécie de cloeodes traver

Estudos realizados principalmente no município de Nova Xavantina, Mato Grosso, levaram-nos à descoberta de diversas espécies de Baetidae. Enquanto uma delas representa uma nova espécie de Cloeodes, aqui descrita, as outras representam novos registros para o estado ou até mesmo para o Brasil. A nova espécie, Cloeodes auwe sp. nov., pode ser diferenciada das demais espécies do gênero pela seguinte combinação de caracteres: padrão de coloração corporal; palpo maxilar longo, porém claramente com dois artículos; terceiro artículo do palpo labial robusto e de ápice truncado; garras relativamente longas (0,5 vezes o comprimento do respectivo tarso), tecas alares posteriores ausentes e número de espinhos na margem posterior do tergito 3 e paraprocto. Além dessa espécie, os seguintes táxons de Baetidae também foram encontrados: Adebrotus amazonicus, Americabaetis alphus, Apobaetis sp., Aturbina georgei, Baetodes sp., Callibaetis sp.1, Callibaetis sp.2, Camelobaetidius janae, Cryptonympha sp., Harpagobaetis gulosus, Paracloeodes binodulus, Spiritiops silvudus, Waltzoyphius fasciatus e Zelusia principalis.

Studies carried mainly in the municipality of Nova Xavantina, Mato Grosso State, have lead us to the discovery of several species of Baetidae. While one of them represents a new species of the genus Cloeodes and is herein described, the others represent new records for the state or even for Brazil. The new species, Cloeodes auwe sp. nov., can be differentiated from the other known species of the genus by the following characteristics: body color pattern, long and two-segmented maxillary palp, third segment of labial palp robust and apically truncate, long tarsal claws (0.5 times the length of the respective tarsus), hind wing pads absent, and number of spines on the posterior margin of the third tergite and on the paraproct. Besides this new species, the following taxa of Baetidae were also found: Adebrotus amazonicus, Americabaetis alphus, Apobaetis sp., Aturbina georgei, Baetodes sp., Callibaetis sp.1, Callibaetis sp.2, Camelobaetidius janae, Cryptonympha sp., Harpagobaetis gulosus, Paracloeodes binodulus, Spiritiops silvudus, Waltzoyphius fasciatus, and Zelusia principalis.