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2.
Rev Esp Enferm Dig ; 102(8): 484-8, 2010 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-20670069

RESUMO

AIM: to evaluate whether the current surveillance programs (ultrasonography and alpha-fetoprotein testing every six months) are successful in detecting patients in the early stages. MATERIAL AND METHODS: the health records of all patients diagnosed with hepatocellular carcinoma in Donostia Hospital between 2003 and 2005 were reviewed retrospectively. Eighty-five patients (11 women and 74 men) were included in the study and demographic data, risk factors and clinical data were obtained. Patients were split into two groups according to whether or not they had been included in a surveillance program. RESULTS: seventy per cent of patients of the surveillance group is diagnosed in early stage opposite to 26.7% of patients in no surveillance group (p < 0.05). Thirteen patients cannot receive curative treatment in spite of the diagnosis in early stage (9 in the surveillance group and 4 in the no surveillance group. The global sensibility of the surveillance program in our series is 95%. CONCLUSIONS: current hepatocellular carcinoma surveillance programs, which comprise six-monthly ultrasonography and alpha-fetoprotein tests, are highly sensitive and effective. These programs result in the detection of hepatocellular carcinoma in its early-stages, when potentially curative treatment may be offered.


Assuntos
Carcinoma Hepatocelular/diagnóstico , Detecção Precoce de Câncer , Neoplasias Hepáticas/diagnóstico , Carcinoma Hepatocelular/sangue , Carcinoma Hepatocelular/diagnóstico por imagem , Carcinoma Hepatocelular/terapia , Feminino , Humanos , Neoplasias Hepáticas/sangue , Neoplasias Hepáticas/diagnóstico por imagem , Neoplasias Hepáticas/terapia , Masculino , Pessoa de Meia-Idade , Vigilância da População , Estudos Retrospectivos , Ultrassonografia , alfa-Fetoproteínas/análise
6.
Rev Esp Enferm Dig ; 89(8): 644-6, 1997 Aug.
Artigo em Espanhol | MEDLINE | ID: mdl-9471207

RESUMO

We report the case of a 70-year-old female with chronic anemia and intestinal pseudoobstruction from a large hamartomatous polyp of the ampulla of Vater. The patient had been operated by obstructive jaundice of possible biliary etiology and a cholecystojejunostomy was performed. Later, due to cholangytis of unknown etiology cholecystectomy and choledochoduodenostomy were done. The polyp was resected by surgery.


Assuntos
Ampola Hepatopancreática , Anemia/etiologia , Neoplasias do Ducto Colédoco/complicações , Pseudo-Obstrução Intestinal/etiologia , Pólipos/complicações , Idoso , Feminino , Humanos
7.
Am J Gastroenterol ; 92(8): 1385-6, 1997 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-9260817

RESUMO

Hepatic rupture is an unusual complication of hepatic amyloidosis. We report the case of a 59-yr-old man with a subcapsular hematoma of the liver with hepatic rupture secondary to amyloidosis. The patient died during the surgery. The etiology, pathology, diagnosis, and treatment of this complication are discussed. Previously reported cases of subcapsular hematoma of the liver secondary to amyloidosis are reviewed. This knowledge and an awareness of the possible diagnosis will help to decrease the high mortality rate associated with this complication.


Assuntos
Amiloidose/complicações , Hepatopatias/complicações , Hepatopatias/etiologia , Adolescente , Adulto , Idoso , Evolução Fatal , Humanos , Masculino , Pessoa de Meia-Idade , Ruptura Espontânea
8.
Gastroenterol Hepatol ; 19(9): 452-5, 1996 Nov.
Artigo em Espanhol | MEDLINE | ID: mdl-8998668

RESUMO

The Peutz-Jeghers syndrome is characterized by gastrointestinal polyposis and mucocutaneous melanin pigmentation. Between the complications are the appearance of gastrointestinal neoplasms. There is an increasing evidence suggesting the hamartoma-adenoma-carcinoma sequence in Peutz-Jeghers syndrome. We present a 32-years-old man with Peutz-Jeghers syndrome who developed an adenocarcinoma arising in a gastric hamartomatous polyp. We discuss the risk to develop gastrointestinal neoplasms and the necessity for periodic surveillance.


Assuntos
Adenocarcinoma/etiologia , Hamartoma/complicações , Síndrome de Peutz-Jeghers/complicações , Pólipos/complicações , Neoplasias Gástricas/etiologia , Adenocarcinoma/patologia , Adenocarcinoma/cirurgia , Adulto , Biópsia , Gastrectomia , Gastroenterostomia , Hamartoma/patologia , Hamartoma/cirurgia , Humanos , Jejuno/cirurgia , Metástase Linfática , Masculino , Pólipos/patologia , Pólipos/cirurgia , Estômago/patologia , Neoplasias Gástricas/patologia , Neoplasias Gástricas/cirurgia
9.
Br J Surg ; 82(5): 638-41, 1995 May.
Artigo em Inglês | MEDLINE | ID: mdl-7613936

RESUMO

Somatostatin and octreotide both enhance closure of gastrointestinal fistulas. The present trial was undertaken to test whether early combined treatment with parenteral nutrition and octreotide 100 micrograms every 8 h by subcutaneous injection had a beneficial effect compared with parenteral nutrition plus placebo. Thirty-one patients with post-operative gastrointestinal or pancreatic fistula were randomly assigned to receive parenteral nutrition plus octreotide (14 patients) or placebo (17) within 8 days of fistula onset. The percentage reduction in output and rate of spontaneous closure within 20 days were analysed. Mean(s.d.) reduction in output was similar after octreotide and placebo at 24 h (66(43) versus 68(47) per cent, P = 0.9), 48 h (60(46) versus 57(43) per cent, P = 0.8) and 72 h (62(50) versus 66(49) per cent, P = 0.9) after starting the combined treatment. Closure within 20 days was observed in eight of 14 fistulas in patients given octreotide and in six of 17 in those receiving placebo (P = 0.4). Administration of octreotide, within 8 days of fistula onset, associated with parenteral nutrition does not significantly increase the spontaneous fistula closure rate compared with parenteral nutrition plus placebo.


Assuntos
Fístula Cutânea/tratamento farmacológico , Fístula Intestinal/tratamento farmacológico , Octreotida/administração & dosagem , Fístula Pancreática/tratamento farmacológico , Idoso , Método Duplo-Cego , Feminino , Humanos , Injeções Subcutâneas , Masculino , Pessoa de Meia-Idade , Nutrição Parenteral , Cuidados Pós-Operatórios , Resultado do Tratamento
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