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1.
World J Orthop ; 14(4): 248-259, 2023 Apr 18.
Artigo em Inglês | MEDLINE | ID: mdl-37155505

RESUMO

BACKGROUND: Advances in minimally invasive surgery and improved post-operative pain management make it possible to consider performing even major foot/ankle operations as day-case. This could have significant benefits for patients and the health service. However there are theoretical concerns about post-operative complications and patient satisfaction due to pain. AIM: To scope the current practice of foot and ankle surgeons on day-case surgery for major foot and ankle procedures in the United Kingdom (UK). METHODS: An online survey (19 questions) was sent to UK foot and ankle surgeons via the British Orthopaedic Foot & Ankle Society membership list in August 2021. Major foot and ankle procedures were defined as surgery that is usually performed as an inpatient in majority of centres and day-case as same day discharge, with day surgery as the intended treatment pathway. RESULTS: 132 people responded to the survey invitation with 80% working in Acute NHS Trusts. Currently 45% of respondents perform less than 100 day-case surgeries per year for these procedures. 78% felt that there was scope to perform more procedures as day-case at their centre. Post-operative pain (34%) and patient satisfaction (10%) was not highly measured within their centres. Lack of adequate physiotherapy input pre/post-operatively (23%) and lack of out of hours support (21%) were the top perceived barriers to performing more major foot and ankle procedures as day-case. CONCLUSION: There is consensus among UK surgeons to do more major foot/ankle procedures as day-case. Out of hours support and physiotherapy input pre/ post-op were perceived as the main barriers. Despite theoretical concerns about post-operative pain and satisfaction this was only measured by a third of those surveyed. There is a need for nationally agreed protocols to optimise the delivery of and measurement of outcomes in this type of surgery. At a local level, the provision of physiotherapy and out of hours support should be explored at sites where this is a perceived barrier.

2.
Gynecol Endocrinol ; 28(12): 965-8, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-22780885

RESUMO

OBJECTIVE: To assess effects of vitamin D and Calcium (Ca) on hormonal and metabolic milieu of polycystic ovary syndrome (PCOS). DESIGN: Single arm open label trial. METHODS: Twelve overweight and vitamin D deficient women with PCOS underwent a 2 hour oral glucose tolerance testing at baseline and following 3-month supplementation with vitamin D (daily dose of 3533 IU, increased to 8533 IU after the first five participants) and 530 mg elemental Ca daily. MAIN OUTCOME MEASURES: Blood pressure (BP), plasma glucose, insulin, total testosterone (T) androstenedione (A), sex hormone binding globulin, lifestyle parameters were assessed at baseline and following 3-month intervention. Insulin resistance (IR) and area under the curve for glucose and insulin were computed; paired analyses were conducted. RESULTS: Improved serum 25OHD (p < 0.001) and reductions in total T (p = 0.036) and A (p = 0.090) levels were noted following 3-month supplementation, compared to baseline. Significant lowering in BP parameters was seen in participants with baseline BP ≥ 120/80 mmHg (n = 8) and in those with baseline serum 25OHD ≤20 ng/ml (n = 9). Parameters of glucose homeostasis and IR remained unchanged (p > 0.05). CONCLUSIONS: Androgen and BP profiles improved followed three month intervention, suggesting therapeutic implications of vitamin D and Ca in overweight and vitamin D deficient women with PCOS.


Assuntos
Cálcio da Dieta/uso terapêutico , Colecalciferol/uso terapêutico , Suplementos Nutricionais , Ergocalciferóis/uso terapêutico , Sobrepeso/complicações , Síndrome do Ovário Policístico/dietoterapia , Deficiência de Vitamina D/dietoterapia , 25-Hidroxivitamina D 2/sangue , Adulto , Índice de Massa Corporal , Calcifediol/sangue , Cálcio da Dieta/efeitos adversos , Colecalciferol/administração & dosagem , Colecalciferol/efeitos adversos , Colecalciferol/metabolismo , Estudos de Coortes , Suplementos Nutricionais/efeitos adversos , Ergocalciferóis/administração & dosagem , Ergocalciferóis/efeitos adversos , Ergocalciferóis/metabolismo , Feminino , Humanos , Hiperandrogenismo/etiologia , Hiperandrogenismo/prevenção & controle , Hipertensão/etiologia , Hipertensão/prevenção & controle , Pacientes Desistentes do Tratamento , Projetos Piloto , Síndrome do Ovário Policístico/complicações , Síndrome do Ovário Policístico/metabolismo , Síndrome do Ovário Policístico/fisiopatologia , Congêneres da Testosterona/sangue , Deficiência de Vitamina D/complicações , Adulto Jovem
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