RESUMO
Coracoid transfer procedures are highly effective at improving glenohumeral stability in patients with recurrent shoulder instability; complication rates from this procedure are generally low. We present the first case in the literature of a Propionibacterium acnes (P. acnes) infection following a coracoid transfer. The case stresses the importance of proper antibiotic prophylaxis for patients undergoing Latarjet procedures, as well as the workup for a painful postoperative shoulder, and the need to maintain cultures from the shoulder for up to 21 days to isolate P. acnes.
Assuntos
Infecções por Bactérias Gram-Positivas/etiologia , Procedimentos Ortopédicos , Articulação do Ombro/microbiologia , Articulação do Ombro/cirurgia , Infecção da Ferida Cirúrgica/microbiologia , Artroscopia , Humanos , Instabilidade Articular/cirurgia , Masculino , Propionibacterium acnes/isolamento & purificação , Luxação do Ombro/cirurgia , Adulto JovemRESUMO
BACKGROUND: Soft tissue defects after TKA are a potentially devastating complication. Medial gastrocnemius flaps occasionally are used to provide soft tissue coverage, most commonly with a periprosthetic joint infection. QUESTIONS/PURPOSES: We asked: (1) What were the rates of persistent or recurrent infection, implant survivorship, flap-related complications, and reoperation for patients who underwent medial gastrocnemius flap reconstruction for soft tissue coverage after TKA? (2) What were the Knee Society clinical and functional scores for patients who underwent medial gastrocnemius flap reconstruction for soft tissue defects after TKA? (3) What were the risk factors for failure of medial gastrocnemius flap reconstruction after TKA, with failure defined as recurrent or new periprosthetic joint infection or inability to reimplant the TKA prosthesis? METHODS: Between 2003 and 2011, four surgeons at one institution performed 31 medial gastrocnemius flaps for soft tissue coverage over an infected TKA. Of those, 27 (87%) were available for followup at a minimum of 2 years (mean, 4 years; range, 2-6 years), although patients experiencing complications or treatment failures before two years were included. The study group consisted of 15 men and 12 women with a mean age of 61 years at the time of surgery (range, 36-86 years). The general indication for using a gastrocnemius flap in this setting was full-thickness soft tissue deficiency over the anterior knee during the course of treatment for concomitant deep infection. Six flaps were performed at prosthetic explantation and antibiotic spacer placement, eight at a spacer exchange, eight at second-stage TKA prosthesis reimplantation, and five at débridement with polyethylene exchange. The decision regarding when during staged treatment to place the flap was based solely on when the soft tissues were deemed insufficient, and not based on a belief that placement at one stage versus another was advantageous. Failure was defined as inability to undergo reimplantation of a TKA prosthesis or recurrence of periprosthetic joint infection. Patient and procedural characteristics were tested for association with failure. Survivorship was calculated by Cox proportional hazards modeling. Outcomes scores were drawn from a longitudinal institutional registry. RESULTS: Fourteen of 27 (52%) patients had a persistent or recurrent infection; survivorship of the TKA prosthesis at 4 years was 48% (95% CI, 31%-66%). Although there were no flap-related complications, 12 patients had a total of 19 reoperations during the study period. Overall, the mean (± SD) Knee Society knee (38 ± 18 vs 65 ± 20; p < 0.001) and function (20 ± 22 vs 37 ± 25; p = 0.002) scores were improved at most recent followup. No factors were identified as associated with failure when a Bonferroni correction was applied. CONCLUSIONS: Gastrocnemius flaps were used to address difficult soft tissue defects in this series, in the presence of deep infections; the high proportion of patients experiencing persistent or recurrent infections reflects the case complexity and not necessarily a problem with the flaps. However, this series highlights the need to continue to explore alternative approaches to managing this difficult clinical problem. Future studies should aim to establish an evidence-based reconstructive algorithm, focusing on host, wound, and timing characteristics that may maximize outcomes. LEVEL OF EVIDENCE: Level IV, therapeutic study.
Assuntos
Artroplastia do Joelho/efeitos adversos , Prótese do Joelho/efeitos adversos , Músculo Esquelético/transplante , Infecções Relacionadas à Prótese/cirurgia , Retalhos Cirúrgicos , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Infecções Relacionadas à Prótese/microbiologia , Recidiva , Resultado do TratamentoRESUMO
Hand surgeons are frequently challenged by the unique requirements of soft tissue coverage of the hand. Whereas many smaller soft tissue defects without involvement of deep structures are amenable to healing by secondary intention or skin grafting, larger lesions and those with exposed tendon, bone, or joint often require vascularized coverage that allows rapid healing without wound contraction. The purpose of this review was to present an overview of local and regional flaps commonly used for soft tissue reconstruction within the hand.
Assuntos
Procedimentos Cirúrgicos Dermatológicos/métodos , Traumatismos da Mão/cirurgia , Mãos/cirurgia , Lesões dos Tecidos Moles/cirurgia , Retalhos Cirúrgicos , Humanos , Transplante de Pele , CicatrizaçãoRESUMO
Eighty-five fixed bearing medial unicompartmental arthroplasties were performed in 42 men and 33 women with a mean age of 49 years (range, thirty-three to fifty-five years old) at the time of surgery. At a mean of 4.0 years (range two to twelve years), the mean pre-operative Knee Society score improved from 49 to 95.1 points (P<0.0001) and the mean UCLA activity score was 7.5 (range 5 to 9). Three knees underwent revision to a total knee arthroplasty; two for arthritic progression in the lateral compartment and one for pain. At the time of final follow-up, two knees (2.4%) demonstrated progressive Grade 4 arthritis of the patellofemoral compartment but were asymptomatic. There was no radiographic evidence of loosening, osteolysis, or premature polyethylene wear. Estimated survivorship was 96.5% at 10 years. UKA offered excellent early outcomes in this cohort of younger, active patients.
Assuntos
Artroplastia do Joelho , Articulação do Joelho/cirurgia , Prótese do Joelho , Osteoartrite do Joelho/cirurgia , Adulto , Feminino , Seguimentos , Humanos , Articulação do Joelho/diagnóstico por imagem , Masculino , Pessoa de Meia-Idade , Radiografia , Amplitude de Movimento ArticularRESUMO
BACKGROUND: There is a paucity of information pertaining to the pathoanatomy and treatment of symptomatic olecranon traction spurs. PURPOSE: To describe the pathoanatomy of olecranon traction spur formation, a technique for spur resection, and a series of patients who failed conservative care and underwent operative treatment. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: Eleven patients (12 elbows) with a mean age of 42 years (range, 27-62 years) underwent excision of a painful olecranon traction spur after failing conservative care. Charts and imaging studies were reviewed. All patients returned for evaluation and new elbow radiographs at an average of 34 months (range, 10-78 months). Outcome measures included the Quick-Disabilities of the Arm, Shoulder, and Hand (QuickDASH) questionnaire; the Mayo Elbow Performance Score (MEPS); visual analog scales (VAS) for pain and patient satisfaction; elbow motion; elbow strength; and elbow stability. RESULTS: The traction spur was found in the superficial fibers of the distal triceps tendon in all cases. The mean QuickDASH score was 3 (range, 0-23), the mean MEPS score was 96 (range, 80-100), the mean VAS pain score was 0.8 (range, 0-3), and the mean VAS satisfaction score was 9.6 (range, 7-10). Average elbow motion measured 3° to 138° (preoperative average, 5°-139°). All patients exhibited normal elbow flexion and extension strength, and all elbows were deemed stable. Early postoperative complications involved a wound seroma in 1 case and olecranon bursitis in 1 case: both problems resolved without additional surgery. Two patients eventually developed a recurrent traction spur, 1 of whom underwent successful repeat spur excision 48 months after the index operation. CONCLUSION: Short- to mid-term patient and examiner-determined outcomes after olecranon traction spur resection were acceptable in our experience. Early postoperative complications and recurrent enthesophyte formation were uncommon. CLINICAL RELEVANCE: This study provides the treating physician with an improved understanding of the pathoanatomy of olecranon traction spur formation, a technique for spur resection, and information to review with patients regarding the outcome of surgical management.
RESUMO
Radioscapholunate arthrodesis is performed for patients who experience pain and disability from radiocarpal arthritis. Initial reports from the 1980s demonstrated high nonunion rates and marginal clinical outcomes. Improvements in surgical technique and clearly defined indications have reduced nonunion rates and improved patient satisfaction. We present a technique using headless compression screws inserted through a dorsal approach, which optimizes hardware placement and incorporates local bone graft harvested from the insertion site to supplement the arthrodesis.
Assuntos
Artrodese/métodos , Parafusos Ósseos , Transplante Ósseo/métodos , Articulações do Carpo/cirurgia , Adulto , Idoso , Articulações do Carpo/diagnóstico por imagem , Articulações do Carpo/fisiopatologia , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Radiografia , Amplitude de Movimento Articular/fisiologia , Medição de Risco , Transplante Autólogo , Resultado do TratamentoRESUMO
BACKGROUND: Although modern-generation rotating-hinge knee implants have been modified to mitigate earlier complications related to aseptic loosening with these devices in revision TKAs, there are few, if any, reports of failure related to the hinge mechanism in these prostheses. CASE DESCRIPTION: We present a case of disengagement of the hinge-post extension in a contemporary rotating-hinge knee prosthesis originally implanted during revision surgery for instability and extensor mechanism insufficiency. We hypothesize the screw home kinematics of the knee resulted in a counterclockwise torque, contributing to the hinge post locking screw disengagement in this case. LITERATURE REVIEW: Although some authors have reported complications and failures related to aseptic loosening with rotating-hinge knee prostheses, there have been no reports regarding complications related to the hinge mechanism, which simultaneously links and permits rotation between the femoral and tibial components. CLINICAL RELEVANCE: Arthroplasty surgeons who use rotating-hinge knee prostheses need to be aware of this potential mode of failure. Design modifications, including more secure locking mechanisms and side-specific implants, may avoid this complication.
Assuntos
Artroplastia do Joelho , Prótese do Joelho , Falha de Prótese , Idoso , Humanos , Articulação do Joelho/diagnóstico por imagem , Articulação do Joelho/cirurgia , Masculino , Polietileno , Desenho de Prótese , RadiografiaRESUMO
The incidence of postoperative infections after spinal surgery ranges from less than 1% to 15%. This rate can vary based on several surgical- and patient-related risk factors, such as the type and duration of the procedure, nutritional status, immunosuppression, and comorbidities of the patient. Most surgeons routinely administer intravenous antibiotics prophylactically, and may employ other measures in an effort to prevent postoperative infection. Multiple diagnostic modalities, in conjunction with examination findings, should be utilized in the assessment of possible postoperative spinal infections. In particular, wound discharge or erythema, and an elevation in the erythrocyte sedimentation rate and C-reactive protein beyond expected postoperative values should raise a clinician's level of suspicion for an infection. The diagnosis of a postoperative spine infection can be difficult to confirm with diagnostic imaging, given findings are not all that different from normal postoperative changes. When suspected, the preferred treatment for a postoperative spinal infection is open irrigation and aggressive debridement of all necrotic tissue and bone, followed by antibiotic treatment based on culture sensitivity.
Assuntos
Antibacterianos/uso terapêutico , Antibioticoprofilaxia/métodos , Coluna Vertebral/cirurgia , Infecção da Ferida Cirúrgica , Quimioterapia Adjuvante , Desbridamento , Humanos , Testes de Sensibilidade Microbiana , Fatores de Risco , Infecção da Ferida Cirúrgica/diagnóstico , Infecção da Ferida Cirúrgica/epidemiologia , Infecção da Ferida Cirúrgica/terapia , Irrigação TerapêuticaRESUMO
BACKGROUND: Computerized tomographic scans are routinely obtained to evaluate a number of musculoskeletal conditions. However, since computerized tomographic scans expose patients to the greatest amounts of radiation of all imaging modalities, the physician must be cognizant of the effective doses of radiation that are administered. This investigation was performed to quantify the effective doses of computerized tomographic scans that are performed for various musculoskeletal applications. METHODS: The digital imaging archive of a single institution was retrospectively reviewed to identify helical computerized tomographic scans that were completed to visualize the extremities or spine. Imaging parameters were recorded for each examination, and dosimetry calculator software was used to calculate the effective dose values according to a modified protocol derived from publication SR250 of the National Radiological Protection Board of the United Kingdom. Computerized tomographic scans of the chest, abdomen, and pelvis were also collected, and the effective doses were compared with those reported by prior groups in order to validate the results of the current study. RESULTS: The mean effective doses for computerized tomographic scans of the chest, abdomen, and pelvis (5.27, 4.95, and 4.85 mSv, respectively) were consistent with those of previous investigations. The highest mean effective doses were recorded for studies evaluating the spine (4.36, 17.99, and 19.15 mSv for the cervical, thoracic, and lumbar spines, respectively). In the upper extremity, the effective dose of a computerized tomographic scan of the shoulder (2.06 mSv) was higher than those of the elbow (0.14 mSv) and wrist (0.03 mSv). Similarly, the effective dose of a hip scan (3.09 mSv) was significantly higher than those observed with knee (0.16 mSv) and ankle (0.07 mSv) scans. CONCLUSIONS: Computerized tomographic scans of the axial and appendicular skeleton are associated with substantially elevated radiation exposures, but the effective dose declines substantially for anatomic structures that are further away from the torso.
Assuntos
Sistema Musculoesquelético/diagnóstico por imagem , Doses de Radiação , Tomografia Computadorizada por Raios X/efeitos adversos , Humanos , Sistema Musculoesquelético/efeitos da radiaçãoRESUMO
BACKGROUND CONTEXT: Osteoporosis and osteomalacia are significant risk factors for fracture and spine instrumentation failure. Low-energy fractures are becoming increasingly more common because of an increase in life expectancy and age of the population. Decreased bone density is an independent risk factor for instrumentation failure in spinal fusion operations. PURPOSE: To assess the awareness and practice patterns of spine surgeons regarding metabolic bone disorders and osteoporosis with emphasis on fracture care and arthrodesis. STUDY DESIGN/SETTING: Questionnaire study. PATIENT SAMPLE: Spine surgeons attending the "Disorders of the Spine" conference (January 2007, Whistler, British Columbia, Canada). OUTCOME MEASURES: Respondent reported frequencies of diagnostics, screening, and treatment methods for patients with low-energy spine fractures, pseudoarthrosis, and those undergoing spinal arthrodesis. METHODS: A ten-question survey was administered to orthopedic surgeons and neurosurgeons who treated spine fractures and degenerative spine conditions in their practice. The survey was given to those who were attending a continuing medical education spinal disorders conference. The survey asked about treatment patterns with respect to osteoporosis and osteomalacia workup and treatment for patients with low-energy spine fractures, pseudoarthrosis, and those undergoing spinal arthrodesis. RESULTS: Of the 133 surgeons to whom the questionnaire was distributed at this meeting, 114 questionnaires were returned that corresponds to a response rate of 86%. Twenty-one surveys were excluded because of incomplete biographical information, resulting in a total of 93 completed questionnaires that were available for analysis. When treating patients with low-energy spine fractures, 60% checked dual-energy X-ray absorptiometry (DEXA) and 39% checked metabolic laboratories (of those who did not order laboratories and DEXA about 63% refer for treatment). Before instrumented fusion, 44% of those queried checked DEXA and 12% checked metabolic laboratories (vitamin D, parathyroid hormone [PTH], and calcium [Ca]). Before noninstrumented fusion, 22% checked DEXA and 11% checked metabolic laboratories. Before addressing pseudoarthrosis, 19% checked DEXA and 20% checked metabolic laboratories. CONCLUSIONS: Despite of the large number of elderly patients undergoing spine care and the high incidence of osteoporosis and/or osteomalacia in this population, a large portion of the spine surgeons who responded to the survey reported that they do not perform routine osteoporosis/osteomalacia workups. Of those who do perform workups, some commented that it will change their surgical plan or preoperative treatment. It appears that there is a need for increased awareness among spine specialists regarding osteoporosis screening and treatment. Osteoporosis practice patterns may also be affected with newly evolving government quality reporting regulations.
Assuntos
Atitude do Pessoal de Saúde , Programas de Rastreamento/estatística & dados numéricos , Osteomalacia/diagnóstico , Osteoporose/diagnóstico , Padrões de Prática Médica/estatística & dados numéricos , Coleta de Dados , Falha de Equipamento , Humanos , Neurocirurgia/instrumentação , Ortopedia , Osteomalacia/complicações , Osteoporose/complicações , Médicos , Pseudoartrose/etiologia , Pseudoartrose/prevenção & controle , Pseudoartrose/terapia , Fatores de Risco , Fraturas da Coluna Vertebral/etiologia , Fraturas da Coluna Vertebral/prevenção & controle , Fraturas da Coluna Vertebral/terapia , Fusão Vertebral/instrumentação , Inquéritos e QuestionáriosRESUMO
Various guidelines have been proposed regarding which portions of a surgical gown may be considered sterile. Unfortunately, the validity of these recommendations has not been definitively established. We therefore evaluated gown sterility after major spinal surgery to assess the legitimacy of these guidelines. We used sterile culture swabs to obtain samples of gown fronts at 6-inch increments and at the elbow creases of 50 gowns at the end of 29 spinal operations. Another 50 gowns were swabbed immediately after they were applied to serve as negative controls. Bacterial growth was assessed using semiquantitative plating techniques on a nonselective, broad-spectrum media. Contamination was observed at all locations of the gown with rates ranging from 6% to 48%. Compared with the negative controls, the contamination rates were greater at levels 24 inches or less and 48 inches or more relative to the ground and at the elbow creases. The section between the chest and operative field had the lowest contamination rates. Based on these results, we consider the region between the chest and operative field to be the most sterile and any contact with the gown outside this area, including the elbow creases, should be avoided to reduce the risk of infection.
Assuntos
Equipamentos Descartáveis/microbiologia , Contaminação de Equipamentos , Controle de Infecções , Procedimentos Ortopédicos/instrumentação , Roupa de Proteção/microbiologia , Coluna Vertebral/cirurgia , Infecção da Ferida Cirúrgica/prevenção & controle , Técnicas Bacteriológicas , Humanos , Guias de Prática Clínica como Assunto , Infecção da Ferida Cirúrgica/microbiologiaRESUMO
BACKGROUND CONTEXT: A variety of orthoses are routinely applied after spinal procedures but there are limited data regarding their efficacy, especially with the increasing use of internal fixation. At this time, the proper indications for postoperative bracing are not well established. PURPOSE: To assess the postoperative bracing patterns of spine surgeons. STUDY DESIGN/SETTING: Questionnaire study. PATIENT SAMPLE: Spine surgeons attending the "Disorders of the Spine" conference (January 2008, Whistler, Canada). OUTCOME MEASURES: Frequencies of bracing after specific surgical procedures. METHODS: A single-page questionnaire was distributed to all spine surgeons attending the "Disorders of the Spine" conference (January 2008). The questionnaire focused on whether surgeons typically immobilize patients after specific spinal procedures, the type of orthosis used, the duration of treatment, and the rationale for bracing. RESULTS: Ninety-eight of 118 surgeons completed the survey (response rate: 83%). The frequency of bracing was similar between academic and private as well as orthopedic and neurosurgical practices. The difference in the bracing tendencies of fellowship and non-fellowship trained surgeons was found to be statistically significant (61% vs. 46%, p<.0001). The duration of clinical experience did not appear to influence the propensity of surgeons to use orthoses. Bracing was employed more regularly after cervical spine procedures than surgeries involving the lumbar spine (63% vs. 49%, p<.0001). In the anterior cervical spine, orthoses were used more often as the complexity of the procedure increased from single to multilevel constructs (55% vs. 76%, p<.0001). The frequencies of bracing were not significantly different between noninstrumented and instrumented lumbar fusions. In most cases, bracing was continued for a total of 3-8 weeks and the restriction of patient activity was the most common reason cited by surgeons who use orthoses. CONCLUSIONS: Although most of the respondents brace their patients postoperatively, there is an obvious lack of consensus regarding the most appropriate type, duration, and indications for immobilization. Further prospective, clinical studies may play a helpful role in evaluating the efficacy of postoperative bracing protocols.
Assuntos
Braquetes/estatística & dados numéricos , Ortopedia/estatística & dados numéricos , Complicações Pós-Operatórias/terapia , Doenças da Coluna Vertebral/cirurgia , Vértebras Cervicais/cirurgia , Pesquisas sobre Atenção à Saúde , Vértebras Lombares/cirurgia , Prática Profissional/estatística & dados numéricos , Fusão Vertebral/estatística & dados numéricos , Inquéritos e QuestionáriosRESUMO
STUDY DESIGN: Prospective study evaluating the sterility of 25 C-arm drapes after their use during spine surgery. OBJECTIVE: To use swab samples to evaluate the sterility of draped C-arms at the end of spine surgical cases and assess the integrity of the sterile technique. SUMMARY OF BACKGROUND DATA: Intraoperative fluoroscopy is used routinely in the operating room for a variety of spinal applications. Although the C-arm may help the surgeon assess spinal alignment and facilitate the placement of instrumentation, there are concerns that the C-arm may represent a potential source of contamination and increase the risk of developing a postoperative infection. METHODS.: This study included 25 surgical cases requiring a standard fluoroscopic C-arm that were performed by 2 spine surgeons. Sterile culture swabs were used to obtain samples from 5 defined locations on the C-arm drape after its use during the operation. The undraped technician's console was sampled in each case as a positive control and an additional 25 C-arm drapes were swabbed immediately after they were applied to the C-arm unit in order to obtain negative controls. Swab samples were assessed for bacterial growth on 5% sheep blood Columbia agar plates using a semiquantitative technique. RESULTS: Contamination was noted on only 1 of 25 negative control drapes at a single location (4%). One hundred percent and 96% of the positive control swabs that were obtained from the negative controls and postoperative drapes exhibited growth, respectively. Although at least some degree of contamination was observed at all locations of the C-arm drape after surgery, the upper 2 sample sites demonstrated the greatest degree of contamination; the incidences of postoperative contamination were significantly greater for the top (56%, P < 0.000001) and upper front of the receiver (28%, P = 0.010) compared to the negative controls. In contrast, the lower front, receiver plate, and midportion of the C-arm were associated with lower rates of contamination (12%-20%). CONCLUSION: The upper portions of the C-arm clearly exhibited the greatest rates of contamination during spinal operations. This contamination most likely occurs when the undraped portions of the C-arm are rotated to acquire lateral images. As a result, we no longer consider the top portion of the C-arm drape to be sterile in these situations and we believe that avoiding contact with these areas may decrease the risks of intraoperative contamination and possibly postoperative infection as well.
Assuntos
Contaminação de Equipamentos/prevenção & controle , Fluoroscopia/instrumentação , Procedimentos Neurocirúrgicos/instrumentação , Coluna Vertebral/microbiologia , Coluna Vertebral/cirurgia , Fluoroscopia/normas , Humanos , Complicações Intraoperatórias/microbiologia , Complicações Intraoperatórias/prevenção & controle , Procedimentos Neurocirúrgicos/métodos , Procedimentos Neurocirúrgicos/normasRESUMO
STUDY DESIGN: Retrospective review and multivariate analysis. OBJECTIVES: Assess lumbar spine segmental range of motion (ROM) with flexion/extension (F/E) radiographs and determine the relation to clinical variables. SUMMARY OF BACKGROUND DATA: Prior studies have investigated the roles of age and degeneration on lumbar segmental ROM only using univariate analyses. Multivariate analyses are also required to differentiate the multiple factors that may affect ROM and quantify their relative effects. METHODS: Radiographs of 258 patients were analyzed, including 137 females and 121 males with ages ranging from 18 to 92 years. Segmental ROM and Kellgren score (KS) of degeneration were assessed for L1-S1. Multivariate regression analyses were performed for each level. Predicting variables evaluated were: (1) KS at the level of interest, (2) KS at the level above, (3) KS at the level below, (4) age, (5) gender, (6) weight, (7) height, (8) body mass index (BMI), and (9) smoking. Significance was defined as P < 0.05. RESULTS: Interobserver reliabilities for assessing KS (ICC 0.70) and segmental ROM (ICC 0.80) were good to excellent. In the multivariate analyses, age had a significant negative association with ROM at L1-L2, L2-L3, L3-L4, and L4-L5. BMI had a significant negative association with ROM at L2-L3, L3-L4, and L4-L5. KS at the level of interest had significant negative association with ROM only at L5-S1. KS at adjacent levels, gender, weight, height, and smoking did not have a significant association with ROM at any level. CONCLUSION: The results of this study provide the clinician with insight into factors that influence segmental lumbar ROM. Age was the strongest statistical predictor of ROM and was associated with declining ROM, amounting to an approximate 3 degrees decrease in total sagittal lumbar ROM in the superior 4 segments every 10 years. BMI was another factor associated with lumbar ROM. Degeneration was a significant predictor of ROM only at L5-S1.
Assuntos
Vértebras Lombares/diagnóstico por imagem , Vértebras Lombares/fisiologia , Amplitude de Movimento Articular/fisiologia , Doenças da Coluna Vertebral/diagnóstico por imagem , Doenças da Coluna Vertebral/fisiopatologia , Adolescente , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Análise Multivariada , Radiografia/normas , Estudos RetrospectivosRESUMO
STUDY DESIGN: The study design consisted of a New Zealand white rabbit model of pseudarthrosis repair. Study groups consisting of no graft, autograft, or recombinant human bone morphogenetic protein-2 (rhBMP-2) with absorbable collagen sponge (ACS) or compression resistant matrix (CRM) were evaluated. OBJECTIVE: To evaluate the relative efficacy of bone graft materials (autograft, ACS, and CRM). SUMMARY OF BACKGROUND DATA: rhBMP-2 has been shown to have a 100% fusion rate in a primary rabbit fusion model, even in the presence of nicotine, which is known to inhibit fusion. METHODS: Seventy-two New Zealand white rabbits underwent posterolateral lumbar fusion with iliac crest autograft. To establish pseudarthroses, nicotine was administered to all animals. At 5 weeks, the spines were explored and all pseudarthroses were redecorticated and implanted with no graft, autograft, rhBMP-2/ACS, or rhBMP-2/CRM. At 10 weeks, fusions were assessed by manual palpation and histology. RESULTS: Eight rabbits (11%) were lost to complications. At 5 weeks, 66 (97%) had pseudarthroses. At 10 weeks, attempted pseudarthrosis repairs were fused in 1 of 16 of no graft rabbits (6%), 5 of 17 autograft rabbits (29%), and 31 of 31 rhBMP-2 rabbits (with ACS or CRM) (100%). Histologic analysis demonstrated more mature bone formation in the rhBMP-2 groups. CONCLUSIONS: The 2 rhBMP-2 formulations led to significantly higher fusion rates and histologic bone formation than no graft and autograft controls in this pseudarthrosis repair model.
Assuntos
Proteínas Morfogenéticas Ósseas/farmacologia , Vértebras Lombares/efeitos dos fármacos , Osseointegração/efeitos dos fármacos , Pseudoartrose/tratamento farmacológico , Proteínas Recombinantes/farmacologia , Fusão Vertebral/efeitos adversos , Fator de Crescimento Transformador beta/farmacologia , Animais , Proteína Morfogenética Óssea 2 , Proteínas Morfogenéticas Ósseas/química , Proteínas Morfogenéticas Ósseas/uso terapêutico , Substitutos Ósseos/química , Transplante Ósseo/efeitos adversos , Química Farmacêutica , Modelos Animais de Doenças , Portadores de Fármacos , Feminino , Humanos , Ílio/transplante , Vértebras Lombares/patologia , Vértebras Lombares/fisiopatologia , Vértebras Lombares/cirurgia , Nicotina , Pseudoartrose/induzido quimicamente , Pseudoartrose/fisiopatologia , Pseudoartrose/cirurgia , Coelhos , Proteínas Recombinantes/química , Proteínas Recombinantes/uso terapêutico , Fatores de Tempo , Tomografia Computadorizada por Raios X , Fator de Crescimento Transformador beta/química , Fator de Crescimento Transformador beta/uso terapêutico , Transplante AutólogoRESUMO
STUDY DESIGN: Retrospective cohort of 258 consecutive patients. OBJECTIVE: The purpose of this study is to determine the: (1) percentage of flexion-extension radiographs that revealed pathology not appreciated on neutral radiographs in the nontrauma population, and (2) frequency that these views led to a change in the management of these patients. SUMMARY OF BACKGROUND DATA: The utility of flexion-extension radiographs in the evaluation of the spine trauma or preoperative patient is well accepted, but the role of dynamic radiographs in the degenerative population is not well defined. METHODS: Consecutive patients presenting with axial cervical, upper extremity radicular, or myelopathic symptoms underwent upright anteroposterior, neutral lateral, and flexion-extension lateral radiographs. Patients with recent trauma, rheumatoid arthritis, prior cervical fracture, prior cervical surgery, inadequate radiographs, or congenital anomalies were excluded. Three observers reviewed all radiographs after determining the best measurement method by a priori analysis of interobserver reliability. RESULTS: Listhesis was observed on 23 of the neutral lateral images; 6 of these were found to have changes between flexion and extension (2-4 mm). Two patients (1%) had spondylolisthesis on flexion-extension radiographs not visualized on neutral lateral radiographs. A subsequent review of these patients' charts revealed no change in management based on these findings. CONCLUSIONS: Cervical flexion-extension radiographs are a method of assessing potential instability. In the degenerative population studied here, 1% had spondylolisthesis noted only on the flexion-extension images, and 3% had a change in spondylolisthesis. None of these, however, led to a changes in clinical management. These data, in conjunction with the extra cost and radiation exposure associated with additional views, led us to no longer regard dynamic radiographs as a useful part of the initial imaging for the patient with degenerative cervical conditions.