RESUMO
We studied disorders in ciliary body microcirculation in experimental chronic glomerulonephritis with tubulointerstitial nephritis and evaluated the hemodynamic effects of low-frequency pulsed electromagnetic field in this pathology. Laser Doppler flowmetry demonstrated vasospasm with reduced nutrient blood fl ow in the ciliary body of animals with experimental chronic glomerulonephritis with tubulointerstitial nephritis. The exposure to low-frequency pulsed electromagnetic field using developed technology will lead to significant reduction of the vascular tone and improve arterial blood supply to the microcirculatory bed.
Assuntos
Corpo Ciliar/efeitos da radiação , Glomerulonefrite/fisiopatologia , Microcirculação/efeitos da radiação , Músculo Liso Vascular/efeitos da radiação , Nefrite Intersticial/fisiopatologia , Espasmo/radioterapia , Animais , Chinchila , Corpo Ciliar/irrigação sanguínea , Corpo Ciliar/fisiopatologia , Radiação Eletromagnética , Fluxometria por Laser-Doppler , Masculino , Músculo Liso Vascular/fisiopatologia , Espasmo/fisiopatologiaRESUMO
Autonomic nervous system disorders occur in 100% cases in patients with connective tissue dysplasia. Biomechanism of accommodation and autonomic innervation of ciliary body was not investigated clearly and presented as area of further research. The goal of the study was to evaluate features of autonomic nervous system in patients with myopia associated with connective tissue dysplasia. 50 children with myopia associated with connective tissue dysplasia went through ophtholmological examination. To evaluate function of autonomic nervous system all patients were observed with the machine "Valenta" which has ECG recording. As a result we found that children with myopia and connective tissue dysplasia have unsatisfactory adaptive reserves with imbalance of sympathetic and parasympathetic input, autonomic nervous system wasn't available to provide homeostasis in demanding level. We hypothesized that autonomic nervous system might be a reason which lead to disorders in process of accommodation during myopia and assist its progressing.