RESUMO
Cryptococcus neoformans is a yeast-like organism associated with pulmonary, meningoencephalitic, or systemic disease. This case report documents 2 cases of cryptococcosis with central nervous system involvement in captive cheetah (Acinonyx jubatus). In both cases the predominant post mortal lesions were pulmonary cryptococcomas and extensive meningoencephalomyelitis. Both cheetahs tested negative for feline immunodeficiency virus and feline leukaemia virus. The organism isolated in Case 2 was classified as Cryptococcus neoformans var. gattii, which is mainly associated with disease in immunocompetent hosts.
Assuntos
Acinonyx , Criptococose/veterinária , Cryptococcus neoformans/classificação , Meningoencefalite/veterinária , Animais , Criptococose/patologia , Criptococose/terapia , Cryptococcus neoformans/isolamento & purificação , Feminino , Pneumopatias Fúngicas/patologia , Pneumopatias Fúngicas/terapia , Pneumopatias Fúngicas/veterinária , Masculino , Meningoencefalite/patologia , Meningoencefalite/terapia , Microscopia EletrônicaRESUMO
Suspected vaccine-induced canine distemper was diagnosed in a captive female bush dog (Speothos venaticus). Macroscopic lesions included mild congestion of the gastric mucosa and focal consolidation of the lung. Histopathological lesions included status spongiosis, gliosis, widespread eosinophilic, intranuclear and intracytoplasmic inclusion bodies in neurons, astrocytes and gitter cells of the cerebral, cerebellar and spinal white matter.