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2.
Rev Esp Med Nucl Imagen Mol ; 32(6): 390-3, 2013.
Artigo em Espanhol | MEDLINE | ID: mdl-23562188

RESUMO

Radiolabeled metaiodobenzylguanidine is an analogue of norepinephrine used to localize tumors that express the neurohormone transporters, specifically those derived from the neural crest having a neuroendocrine origin. It is also used to treat non-surgical metastases derived from them. A review of the literature revealed symptomatic improvements associated to a decrease in hormone levels in a significant percentage of patients after (131)I-MIBG treatment. However, complete tumor remission has been described only in very few cases and hardly ever when bone metastases exist. We present a case of a patient diagnosed of malignant pheochromocytoma who achieved complete hormonal and metabolic response after (131)I-MIBG treatment (600 mCi) in spite of the presence of bone metastases.


Assuntos
3-Iodobenzilguanidina/uso terapêutico , Neoplasias das Glândulas Suprarrenais/tratamento farmacológico , Antineoplásicos/uso terapêutico , Feocromocitoma/tratamento farmacológico , Neoplasias das Glândulas Suprarrenais/metabolismo , Neoplasias das Glândulas Suprarrenais/patologia , Neoplasias Ósseas/secundário , Humanos , Masculino , Neurotransmissores/biossíntese , Feocromocitoma/metabolismo , Feocromocitoma/secundário , Indução de Remissão , Adulto Jovem
3.
Rev Esp Med Nucl ; 30(1): 24-8, 2011.
Artigo em Espanhol | MEDLINE | ID: mdl-20863596

RESUMO

Differentiated thyroid cancer is a disease having a very good prognosis when treated adequately. Ablation treatment with (131)I is frequently adjunct to surgery in these patients since it improves survival. Radioiodine whole-body scan is one of the imaging modality of choice in the follow-up of patients with this kind of pathology. After ablation treatment of the thyroid gland, any radioiodine accumulation in a non-physiological location usually means the presence of functioning metastasis. Recognition of potential false-positives is essential to avoid unnecessary exposure to further radiation from repeated therapeutic doses of radioactive iodine. We report a case of uptake in the chest due to bronchiectasis, potentially masquerading as pulmonary metastasis.


Assuntos
Bronquiectasia/diagnóstico por imagem , Carcinoma/diagnóstico por imagem , Radioisótopos do Iodo/farmacocinética , Pulmão/diagnóstico por imagem , Compostos Radiofarmacêuticos/farmacocinética , Neoplasias da Glândula Tireoide/diagnóstico por imagem , Imagem Corporal Total , Idoso , Antibacterianos/uso terapêutico , Biomarcadores Tumorais , Bronquiectasia/etiologia , Bronquite/complicações , Bronquite/tratamento farmacológico , Carcinoma/sangue , Carcinoma/radioterapia , Carcinoma/secundário , Carcinoma/cirurgia , Terapia Combinada , Diagnóstico Diferencial , Reações Falso-Positivas , Feminino , Humanos , Radioisótopos do Iodo/uso terapêutico , Neoplasias Pulmonares/diagnóstico , Neoplasias Pulmonares/secundário , Cintilografia , Compostos Radiofarmacêuticos/uso terapêutico , Tireoglobulina/sangue , Neoplasias da Glândula Tireoide/sangue , Neoplasias da Glândula Tireoide/radioterapia , Neoplasias da Glândula Tireoide/secundário , Neoplasias da Glândula Tireoide/cirurgia , Tireoidectomia
4.
Rev Esp Med Nucl ; 19(5): 356-60, 2000 Sep.
Artigo em Espanhol | MEDLINE | ID: mdl-11062112

RESUMO

This paper aims to present the usefulness of the different diagnosis imaging methods (anatomical and functional) in the characterization of bone injury. Any data, however insignificant, is justified and should be specified. In this case, the discrepancy between the vascular and pool phases in the bone scintigraphy with 99mTc-MDP reveals revealed a lesion with an intense reaction secondary to the "foreign body effect", which is not necessarily malignant.


Assuntos
Neoplasias Femorais/diagnóstico por imagem , Osteoma Osteoide/diagnóstico por imagem , Compostos Radiofarmacêuticos , Medronato de Tecnécio Tc 99m/análogos & derivados , Adolescente , Diagnóstico Diferencial , Reação a Corpo Estranho/diagnóstico por imagem , Humanos , Imageamento por Ressonância Magnética , Cintilografia
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