RESUMO
AIMS: To evaluate the efficacy and clinical impact of FDG-PET in patients with suspected recurrent laryngeal carcinoma. MATERIALS AND METHODS: 15 patients, with suspicion of recurrent laryngeal carcinoma and ambiguous conventional imaging modalities. In all patients a whole body scan was performed with FDG-PET in fasting patients following i.v. administration of 370-444 MBq FDG. The results were confirmed by histology and clinical evolution (follow-up period > 12 months). RESULTS: Prevalence of recurrence was 86.6%. FDG-PET was positive in 13 patients, with confirmation in all cases, and 2 were true negative (TN). Overall sensitivity, specificity, PPV, NPV and accuracy were 100%. FDG-PET changed the modality of treatment in 10 patients (clinical impact 63.3%). CONCLUSIONS: FDG-PET has high clinical impact in patients with a suspicion of recurrent laryngeal carcinoma, and should be incorporated to the diagnostic protocols before making a therapy decision.
Assuntos
Carcinoma/diagnóstico por imagem , Fluordesoxiglucose F18 , Neoplasias Laríngeas/diagnóstico por imagem , Recidiva Local de Neoplasia/diagnóstico por imagem , Tomografia por Emissão de Pósitrons , Compostos Radiofarmacêuticos , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos RetrospectivosAssuntos
Corticosteroides/uso terapêutico , Hemangioma/tratamento farmacológico , Hemangioma/patologia , Neoplasias Laríngeas/tratamento farmacológico , Neoplasias Laríngeas/patologia , Laringe/patologia , Corticosteroides/administração & dosagem , Feminino , Hemangioma/diagnóstico , Humanos , Lactente , Neoplasias Laríngeas/diagnóstico , MasculinoRESUMO
In this study we presents: 6 subglottic stenosis, 2 subglottic hemangiomas, 2 laryngeal webs, 2 laryngeal cysts and 1 laryngoesophageal cleft. Were diagnosed during laryngotracheobronchoscopies performed to 220 newborns and small children that showed as main finding: stridor, voice change or aspiration syndrome. The stenosis, hemangiomas and cleft were resolved spontaneously. In the webs and cysts surgical correction was required. Here we will expound upon clinical, diagnostical and therapeutic aspects of these rare congenital laryngeal anomalies.
Assuntos
Doenças da Laringe/congênito , Laringe/anormalidades , Anormalidades Congênitas/terapia , Feminino , Humanos , Recém-Nascido , Doenças da Laringe/terapia , MasculinoRESUMO
Four cases of Histiocytosis X are presented here, with symptoms otorhinolaryngologic. The evolution has been good, so they have been without disease for three of four years. We are presenting the problem of differential diagnosis of this disease for ENT specialists and the delay in the diagnosis. All our cases were diagnosed after one year of the beginning of symptoms.