RESUMO
The surgical strategy to resolve the underlying biliary pathology in patients with acute gallstone pancreatitis (AGP) remains controversial. The aim of this study was to evaluate the safety and effectiveness of early laparoscopic cholecystectomy (ELC) in patients with mild AGP. A retrospective cohort of consecutive patients diagnosed with mild AGP according to the Atlanta Guidelines from January 2009 to July 2019 was selected. Patients were assigned to surgery on the first available surgical shift, 48 h after the symptoms onset. Univariate analysis was performed to determine the association between AGP and grades of Balthazar (A, B and C) with time to surgery, days of hospitalization and postoperative complications. From 239 patients evaluated, 238 (99.58%) were operated by laparoscopic approach. Intraoperative cholangiogram was performed routinely. Choledocholithiasis, if present, was successfully treated by laparoscopic common bile duct exploration in all cases. A significant association was found between Balthazar grades and time to surgery (median of 3 days, p = 0.003), with length hospitalization and from surgery to discharge, with median of 4 days (p = 0.0001) and 2 days (p = 0.003), respectively. Mild postoperative complications (CD I/II) were observed in 22/239 patients (9.2%). This represents 2% of patients with grade A of Balthazar, 9% of grade B and 14% of grade C (p = 0.016). We observed no severe complications or mortality. ELC with routine intraoperative cholangiogram, performed on the first available surgical shift 48 h after the symptoms of pancreatitis onset, is a viable, effective and safe strategy for the resolution of mild AGP and its underlying biliary pathology in a single procedure.
Assuntos
Colecistectomia Laparoscópica/métodos , Cálculos Biliares/cirurgia , Pancreatite/cirurgia , Segurança , Estudos de Coortes , Humanos , Estudos Retrospectivos , Índice de Gravidade de Doença , Resultado do TratamentoRESUMO
El soporte nutricional óptimo en el campo de la cirugía pancreática aún es objeto de debate. Se buscó evaluar la importancia de la evaluación nutricional en pacientes con resecciones pancreáticas. Análisis retrospectivo de una base de datos prospectiva. Se realizó evaluación nutricional sistemática. Las variables analizadas fueron, tiempo de estadía hospitalaria y en UTI, complicaciones y mortalidad. No se observaron diferencias estadísticamente significativas usando test de forma aislada. Sin embargo la asociación de desnutrición severa por más de un test se asoció a un aumento significativo en la mortalidad post-operatoria. La evaluación interdisciplinaria de los pacientes con tumores bilio-pancreáticos, debe incluir una adecuada valoración del estado nutricional para identificar aquellos con mayor riesgo
The optimal nutritional support in pancreatic surgery is still under debate. We performed a retrospective analysis of a prospective data base. Systematic nutritional assessment was performed. Length of hospital stay and in ICU, morbidityand mortality, were analyzed. We didn't find significative differences between any of the nutritional test. However, patients with severe malnutrition in different tests were associated with higher mortality. Interdisciplinary management of patients with biliopancreatic tumors should include an adequate nutritional evaluation to identify high risk patients.
Assuntos
Pancreatopatias , Cirurgia Geral , Avaliação Nutricional , Apoio NutricionalRESUMO
INTRODUCCIÓN: La escasez de donantes para suplir la demanda de trasplantes es un problema Mundial. "Hígados que nadie quiere" (HNQ) define injertos que fueron rechazados numerosas veces por varios centros antes de su aceptación. OBJETIVO: evaluar los resultados en la utilización de "HNQ" en nuestro centro. Fuente de datos CRESI-SINTRA y una base prospectiva, Periodo 2013-2016. MÉTODOS: Estudio retrospectivo, dos grupos pre-determinados: 1. Pacientes que recibieron un órgano más allá del percentilo 75 de mediana de rechazos 2. Resto de los receptores. RESULTADOS: Se realizaron 1325 trasplantes a nivel nacional, con una mediana de rechazos previos al implante de 5 (IQR3-11). 153 fueron realizados en el HEC y la mediana de rechazos fue de 7 (IQR3-18); 55/36% de esos injertos mas allá de p75, ninguno fue usado para falla fulminante. Comparando 1 vs 2 (55 vs 72), no hubo diferencias estadísticamente significativas en la edad (51 años IQR45-60 vs 50 años IQR39-59 p=0.53), incidencia de falla primaria del injerto (RR 0.65 IC95%0.33-1.32 p=0.19), extubacion temprana (RR 1.16 IC95%0.43-3.16p=0.78),o diálisis (RR 1.36 IC95%0.84-2.21 p=0.26); tampoco en la duración de estadía en UTI (4 días IQR3-6 vs 5 días IQR 3-9 p=0.12) u hospitalaria (8 días IQR 6-14 vs 1.5 días IQR 8-17.5 p=0.06), sobrevida del injerto (p=0.51) y del paciente (p=0.59). El MELD del receptor fue la única diferencia (24 IQR22-25 vs 28 IQR25-33 p<0.05: Un tercio de la población de nuestro centro recibió "HNQ" (injertos rechazados previamente 12 veces), con similares resultados. Futuras investigaciones deberían determinar la causa de esos rechazos.
INTRODUCTION: Donor scarcity to supply the demand for transplants is a global problem. "Livers that nobody wants" (LNW) are those grafts that were refused by several centers multiple times before being accepted. OBJECTIVE: to evaluate the results in the use of "LNW" in our center. Data source: CRESI-SINTRA and a prospective database, period 2013-2016. METHODS: Retrospective study in two predetermined groups: 1. Patients who received an organ beyond the 75th percentile of median rejections 2. The rest of recipients. RESULTS: At national level, 1325 transplantations were made, its median refusals prior to implantation being 5 (IQR3-11), of which 153 were made in the HEC and the median refusals were 7 (IQR3-18); out of 55/36% of these grafts beyond the 75th p, none were used in fulminant hepatic failure. In comparing 1 vs 2 groups (55 vs 72), there were no statistically significant differences in age (51 years IQR45-60 vs 50 years IQR39-59 p=0.53), incidence ofdraft primary failure (RR 0.65 IC95%0.33-1.32 p=0.19), early extubation (RR 1.16 IC95%0.43- 3.16p=0.78),or dialysis requirement (RR 1.36 IC95%0.84-2.21 p=0.26); there were no differences either in the ICU stay (4 days IQR3-6 vs 5 days IQR 3-9 p=0.12) or in hospital stay(8 days IQR 6-14 vs 1.5 days IQR 8-17.5 p=0.06), draft survival (p=0.51) and patient survival (p=0.59). The only difference was in the MELD score of the receptor (24 IQR22-25 vs 28 IQR25-33 p<0.05:). A third of the population in our center received LNW (drafts previously refused 12 times) and showed similar results. The cause of these refusals should be determined by future research.
Assuntos
Humanos , Rejeição de Enxerto , Transplante de Fígado , Doadores de TecidosRESUMO
El diagnóstico de coledocolitiasis está basado en la anamnesis, el exámen físico y los exámenes de laboratorio. En la actualidad los estudios por imágenes tienen una alta sensibilidad y especificidad, sin embargo, es importante utilizarlos con racionalidad. Muchos de los estudios comentados previamente pueden presentar complicaciones, desde una pancreatitis severa post-cpre hasta un shock anafiláctico por el contraste EV de una TAC. Es importante evaluar los riesgos y los beneficios que cada estudio diagnóstico representan para el paciente, teniendo en cuenta la presentación clínica y sus antecedentes, así como la disponibilidad de los mismos en el medio en el que nos encontramos.
Assuntos
Coledocolitíase , Cálculos Biliares , LitíaseAssuntos
Implante de Prótese Vascular , Hepatectomia , Veias Hepáticas/cirurgia , Neoplasias Hepáticas/secundário , Neoplasias Hepáticas/cirurgia , Procedimentos de Cirurgia Plástica , Derivação Portocava Cirúrgica , Neoplasias Retais/patologia , Veia Cava Inferior/cirurgia , Adulto , Feminino , Veias Hepáticas/patologia , Humanos , Veia Ilíaca/transplante , Imageamento por Ressonância Magnética , Invasividade Neoplásica , Grampeamento Cirúrgico , Resultado do Tratamento , Veia Cava Inferior/patologiaRESUMO
BACKGROUND: The endogenous hyperinsulinemic hypoglicemia syndrome (EHHS) can be caused by an insulinoma, or less frequently, by nesidioblastosis in the pediatric population, also known as non insulinoma pancreatic hypoglycemic syndrome (NIPHS) in adults. The aim of this paper is to show the strategy for the surgical treatment of ehhs. MATERIAL AND METHODS: A total of 19 patients with a final diagnosis of insulinoma or NIPHS who were treated surgically from january 2007 until june 2012 were included. We describe the clinical presentation and preoperative work-up. Emphasis is placed on the surgical technique, complications and long-term follow-up. RESULTS: All patients had a positive fasting plasma glucose test. Preoperative localization of the lesions was possible in 89.4% of cases. The most frequent surgery was distal pancreatectomy with spleen preservation (9 cases). Three patients with insulinoma presented with synchronous metastases, which were treated with simultaneous surgery. There was no perioperative mortality and morbidity was 52.6%. Histological analysis revealed that 13 patients (68.4%) had benign insulinoma, 3 malignant insulinoma with liver metastases and 3 with a final diagnosis of SHPNI. Median follow-up was 20 months. All patients diagnosed with benign insulinoma or NIPHS had symptom resolution. CONCLUSION: The surgical treatment of EHHS achieves excellent long-term results in the control of hypoglucemic symptoms.
Assuntos
Hiperinsulinismo/cirurgia , Hipoglicemia/cirurgia , Insulinoma/cirurgia , Neoplasias Pancreáticas/cirurgia , Adulto , Idoso , Feminino , Humanos , Hiperinsulinismo/complicações , Hipoglicemia/etiologia , Insulinoma/complicações , Masculino , Pessoa de Meia-Idade , Neoplasias Pancreáticas/complicações , Estudos Retrospectivos , Síndrome , Adulto JovemRESUMO
Benign liver tumors are common lesions that can be classified into cystic and solid lesions. Cystic lesions are the most frequent; however, they rarely represent a diagnostic or therapeutic challenge. In contrast, solid lesions are more difficult to characterize and management remains controversial. The wide availability and use of advanced imaging modalities, including ultrasonography, computed tomography, and magnetic resonance imaging have led to increased identification of incidental liver masses. Although some of these incidentally discovered masses are malignant, most are benign and must be included in the differential diagnosis. In this article we review FNH and HA. Its etiology, biological behavior, diagnosis, and treatment will be highlighted.
Assuntos
Adenoma/diagnóstico , Adenoma/terapia , Hiperplasia Nodular Focal do Fígado/diagnóstico , Hiperplasia Nodular Focal do Fígado/cirurgia , Neoplasias Hepáticas/diagnóstico , Neoplasias Hepáticas/cirurgia , Adenoma/patologia , Hiperplasia Nodular Focal do Fígado/patologia , Hiperplasia Nodular Focal do Fígado/fisiopatologia , Humanos , Fígado/diagnóstico por imagem , Neoplasias Hepáticas/patologia , Imageamento por Ressonância Magnética , Tomografia Computadorizada por Raios X , UltrassonografiaRESUMO
El diagnóstico de pancreatitis crónica requiere una alta sospecha por parte del médico de atención primaria. Por este motivo debe ser tenida en cuenta como diagnóstico diferencial ante un paciente que presenta dolor abdominal recurrente, consumo elevado de alcohol y síntomas de malabsorción. En la presente revisión narrativa los autores hacen referencia a aspectos generales de esta enfermedad: desde su oscura etiología y fisiopatología, hasta las dificultades actuales en su tratamiento.