Determination of the levels and possible associations of alpha2-macroglobulin with autoantibodies in the serum of patients with various forms of autoimmune thyroiditis.

Antibodies to thyroid peroxidase (AB-TPO), antibodies to thyroglobulin (AB-TG), and the content of α2-macroglobulin (α2-MG) have been studied in serum samples of patients with autoimmune thyroiditis (AIT). All the patients were divided into 3 groups depending on age: 25-35, 36-50, 51-65 years. We found a significant change in the thyroid panel parameters in AIT, but without significant changes in the average concentration of α2-MG in the age groups of patients. This may be due to the accumulation and retention of complexes of defective forms of α2-MG in the circulation associated with their decreased ability to bind to receptors.

[Prevalence of congenital dislocation of hip diffusion among the population of Lenkoran and Massaly region in Azerbaijan].

The occurrence of congenital hip dislocation in Lenkoran and Massaly areas of Azerbaijan Republic was studied. The population-genetic assessment in Lenkoran and Massaly regions was conducted. The phenotypic frequency of hip congenital dislocation according to Medical- Labor Expert Commission data are 0,065% and 0,035% respectively. According to present survey congenital hip dislocation data are: 0, 7% and 0, 4% respectively. The results of the study demonstrate strong demand of accurate data on the occurrence of congenital and genetic diseases in Azerbaijan Republic. The highest prevalence of multiple-factor type of heredity indicates the necessity to control teratogen factors of the environment.