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1.
Am J Obstet Gynecol ; 227(2): B2-B10, 2022 08.
Artigo em Inglês | MEDLINE | ID: mdl-35487325

RESUMO

The processes of diagnosis and management involve clinical decision-making. However, decision-making is often affected by cognitive biases that can lead to medical errors. This statement presents a framework of clinical thinking and decision-making and shows how these processes can be bias-prone. We review examples of cognitive bias in obstetrics and introduce debiasing tools and strategies. When an adverse event or near miss is reviewed, the concept of a cognitive autopsy-a root cause analysis of medical decision-making and the potential influence of cognitive biases-is promoted as part of the review process. Finally, areas for future research on cognitive bias in obstetrics are suggested.


Assuntos
Cognição , Erros Médicos , Obstetrícia , Viés , Humanos , Perinatologia , Sociedades Médicas , Estados Unidos
2.
Am J Obstet Gynecol ; 223(3): B2-B6, 2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-32470457

RESUMO

Recent surveys have shown widespread lapses in the procedures used to reduce the risk of transmitting infection via medical devices. Transvaginal ultrasound examination has the potential to transmit vaginal infections, including human papillomavirus. Areas of particular concern are the use of probe covers with high rates of leakage, disinfectants that are not effective against human papillomavirus, and coupling gel from multiple-use containers. We reviewed these issues, and we recommend 4 steps to reduce the risk of transmitting infection. First, during every transvaginal ultrasound exam, the probe should be covered with a sterile, single-use "viral barrier" cover or a condom. Second, sterile, single-use ultrasound gel packets should be used. Third, after every examination, the probe should be cleaned to remove any visible gel or debris. Finally, after cleaning, the probe should undergo high-level disinfection using an agent with proven efficacy against the human papillomavirus, including hydrogen peroxide, hypochlorite, or peracetic acid. Glutaraldehyde, orthophthalaldehyde, phenols, and isopropyl alcohol have virtually no efficacy against the human papillomavirus.


Assuntos
Transmissão de Doença Infecciosa/prevenção & controle , Contaminação de Equipamentos/prevenção & controle , Ultrassonografia Pré-Natal/instrumentação , Doenças Vaginais/microbiologia , Doenças Vaginais/prevenção & controle , Desinfetantes , Desinfecção/métodos , Equipamentos Descartáveis , Feminino , Glutaral , Humanos , Controle de Infecções/métodos , Infecções por Papillomavirus/prevenção & controle , Gravidez , Esterilização/métodos , Ultrassonografia Pré-Natal/efeitos adversos , Doenças Vaginais/virologia , o-Ftalaldeído
3.
Reprod Sci ; 15(1): 51-8, 2008 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-18212354

RESUMO

The authors test single nucleotide polymorphisms (SNPs) in coding sequences of 12 candidate genes involved in glucose metabolism and obesity for associations with spina bifida. Genotyping was performed on 507 children with spina bifida and their parents plus anonymous control DNAs from Hispanic and Caucasian individuals. The transmission disequilibrium test was performed to test for genetic associations between transmission of alleles and spina bifida in the offspring (P < .05). A statistically significant association between Lys481 of HK1 (G allele), Arg109Lys of LEPR (G allele), and Pro196 of GLUT1 (A allele) was found ( P = .019, .039, and .040, respectively). Three SNPs on 3 genes involved with glucose metabolism and obesity may be associated with increased susceptibility to spina bifida.


Assuntos
Transtornos do Metabolismo de Glucose/genética , Transportador de Glucose Tipo 1/genética , Hexoquinase/genética , Receptores para Leptina/genética , Disrafismo Espinal/genética , Catalase/genética , Feminino , Perfilação da Expressão Gênica , Genes p53 , Predisposição Genética para Doença , Genótipo , Transtornos do Metabolismo de Glucose/etnologia , Hispânico ou Latino/estatística & dados numéricos , Humanos , Leptina/genética , Masculino , Obesidade/etnologia , Obesidade/genética , Polimorfismo de Nucleotídeo Único , Receptor de Insulina/genética , Disrafismo Espinal/etnologia , Superóxido Dismutase/genética , População Branca/estatística & dados numéricos
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