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1.
Transl Androl Urol ; 13(3): 423-432, 2024 Mar 31.
Artigo em Inglês | MEDLINE | ID: mdl-38590965

RESUMO

Background: Lichen sclerosus (LS) is considered a causative factor in 10% of cases of idiopathic urethral stricture disease (IUSD), which is important for determining management strategies due to the underlying pathophysiology. Traditional excision urethroplasty may not be effective as inflammation often extends beyond the macroscopic stricture. This pilot study aims to answer two research questions: is LS an underlying cause of some idiopathic cause of strictures, and, if there is histological evidence suggesting predisposition of the surrounding tissue to strictures. Methods: Biopsies were taken from the stricture site as well as 1 and 2 cm proximal and distal in patients with IUSD. Histological features, including macroscopic and microscopic findings, were reported, including the presence of LS, hyperkeratosis, epidermal changes, lichenoid infiltrates, ulceration, scarring, and inflammation. Methylene blue was used to aid in locating damaged urothelium. Patients were prospectively followed up after urethroplasty. Results: From 109 urethroplasties performed between 2019 to 2022, 15 male patients were enrolled after meeting specific inclusion criteria. These criteria included a diagnosis of IUSD and the absence of any evidence of trauma, macroscopic inflammatory disease, or previous endoscopic instrumentation of the urethra. Patients had to be at least 16 years old and medically suitable for undergoing urethroplasty. The study was approved by the hospitals ethics committees. None had macroscopic evidence of LS. One patient had microscopic evidence of LS at the 2 cm proximal biopsy only. A total of 93% of patients had scarring proximal and distal to the stricture, while 20-40% had inflammatory change. The patient with microscopic LS and two inflammatory change patients had stricture recurrence after urethroplasty. Additionally, one patient with inflammatory changes was diagnosed with penile intraepithelial neoplasia (PeIN) and underwent partial penectomy. Conclusions: Findings suggest that an underlying cause of IUSD could be LS. Additionally, the pathophysiology may involve scarring and inflammation beyond the limits of the stricture with extension distal from the stricture site. Careful evaluation for concomitant urethral pathology should be considered in cases of inflammatory changes. These findings should be considered in the surgical management of IUSD and warrant further research into the role of routine biopsy and drug targets in USD.

2.
3.
J Pediatr Urol ; 20(2): 305-311, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38000949

RESUMO

OBJECTIVES: We enumerate the various laparoscopic strategies to resolve upper urinary tract (UUT) obstruction in the context of variations in anatomy and report their outcomes. PATIENTS AND METHODS: Retrospective review of primary laparoscopic UUT reconstructions performed between May 2012 and May 2021. Anomalies included: malrotated kidney (MRK), horseshoe kidney (HSK), duplex kidney (DK), pure intrarenal pelvis (IRP) and mid-ureteric stenosis (MUS). Success was defined by postoperative resolution of symptoms, improvement of anterior-posterior renal pelvic diameter (APD) on US and drainage on Mag3. Complications were categorised by Clavien-Dindo grading. Outcomes compared using the student's t-test with P < 0.05 considered statistically significant. RESULTS: Of the 214 laparoscopic primary UUT reconstructions, 37 (17.2 %) were: 13-MRK, 12-HSK, 4-DK, 4-IRP and 4-MUS. Median age at surgery was 5-years (range 0.3-15). Dismembered pyeloplasty: 8; pyeloplasty with renal sinus dissection: 8; neo-PUJ anastomosis: 8; primary ureterocalycostomy: 7; pyeloureterostomy: 2; and uretero-ureterostomy: 4. Median follow-up was 43-months (range 8-108) with a success rate of 94.5 % (35/37). Complete resolution of symptoms in 20/21 patients; improvement of hydronephrosis on US in 35/37 patients (median pre-operative APD 27 mm vs. median postoperative APD 8 mm) [P < 0.001]; improvement of drainage on diuretic renogram in 32/34 kidneys and stable/improved DRF in 34/35 kidneys (median preoperative DRF - 45 % vs. median postoperative DRF - 47 %) [P > 0.05]. Postoperative complications managed medically (II Clavien) included urinary tract infections - 2 patients (5 %), stent-related symptoms in 2 (5 %) and umbilical port site collection in 1 patient (3 %). Recurrent pelvi-ureteric junction obstruction PUJO occurred in one patient (3 %) requiring redo surgery (IIIb Clavien), renal stones in 1 (3 %) which resolved with ESWL (IIIb Clavien); in 1 (3 %) patient with a HSK there was complete loss of ipsilateral kidney function but this was managed conservatively up to date (I Clavien). CONCLUSION: Laparoscopic transperitoneal approach allows the prompt recognition of in-situ anatomical variants. UUT obstruction in such settings calls for a variety of strategies with excellent outcomes.

4.
J Pediatr Urol ; 20(2): 165-172, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-37487882

RESUMO

INTRODUCTION: Several patients, who underwent major reconstruction under the care of an experienced pediatric urologist are now, as adults, several years later, appearing with long term problems and complications. This consensus process was undertaken to give an overview of long term consequences (and their management) of urological childhood surgery. MATERIAL AND METHODS: Several known urologists with experience in life-long follow up and revisional surgery of patients with congenital conditions were asked to review literature and comment based on their experience about several complications of childhood surgery. RESULTS: Renal impairment, metabolic consequences, bladder stones, Vit B 12 deficiency and recurrent infections are often encountered. Also recurrent ureteric strictures and difficulties with catheterizable channel (both obstruction and incontinence) can be challenging to manage. Specific attention is needed regarding female sexuality and pregnancy. Both the development of malignancies in reconstructed bladders as secondary malignancies need to be taken into account during follow up. CONCLUSION: Follow up of patients with rare congenital conditions is highly specialized and revisional surgery can be challenging. Therefore, follow up needs to be organized in specialized centers.

5.
Pediatr Surg Int ; 39(1): 293, 2023 Nov 16.
Artigo em Inglês | MEDLINE | ID: mdl-37971531

RESUMO

INTRODUCTION: Cloacal malformation is a rare anomaly that remains a diagnostic challenge prenatally, despite the current advances in ultrasonography and MRI. This condition can in some, present with isolated ascites or with other findings, such as a pelvic cyst or upper urinary tract dilatation. In a minority, the ascites may be progressive, questioning the role of antenatal intervention. METHODS: We report on ten patients that have been identified from our Cloaca database between 2010 and 2022. RESULTS: The presence of ascites was associated with extensive bowel adhesions and matting, leading to a challenging initial laparotomy and peri-operative course. CONCLUSIONS: Antenatal finding of ascites in newborns with cloacal malformations should raise a red flag. The surgeon and anaesthetist should be prepared for the operative difficulties secondary to bowel adhesions and the higher risk of haemodynamic instability at the initial surgery. An experienced team at initial laparotomy in such patients is vital. LEVEL OF EVIDENCE: II.


Assuntos
Ascite , Cloaca , Gravidez , Humanos , Recém-Nascido , Feminino , Animais , Ascite/diagnóstico por imagem , Ascite/etiologia , Cloaca/diagnóstico por imagem , Cloaca/cirurgia , Cloaca/anormalidades , Ultrassonografia , Imageamento por Ressonância Magnética , Ultrassonografia Pré-Natal
6.
J Pediatr Urol ; 19(1): 36.e1-36.e7, 2023 02.
Artigo em Inglês | MEDLINE | ID: mdl-37856541

RESUMO

INTRODUCTION: Bladder exstrophy and epispadias complex (BEEC) is a spectrum of congenital malformations ranging from an isolated epispadias to a full exstrophy. It is an uncommon disease and little is known on how patients cope with its implications later in life. OBJECTIVE: The goal of this study is to assess the sexual, continence and fertility outcomes of BEEC patients, who had reconstructive bladder surgery during childhood. Considering the sensitive nature of these topics, they are not easily spoken about in the doctor's office. Our aim is to shed some light on possible points of improvement in follow-up. STUDY DESIGN: 63 patients between 18 and 45 years old were sent an electronic questionnaire based on previous existing standardized questionnaires. They were asked about sexual and psychosexual wellbeing, urinary incontinence and fertility. Data from their medical files (medical history on previous surgeries). and questionnaire answers are linked through an anonymous subject number and put into an Excel file for descriptive representation. RESULTS: 22 men and 8 women filled in the questionnaire. All but 2 are sexually active. Reasons to avoid sexual activity are equally divided as BEEC-related and non-BEEC-related. Sexual satisfaction is lower in the male group due to problems with erection, ejaculation, condom usage and embarrassment about physical appearance. In females problems concerning pain and reaching orgasm are mentioned. 30% report depressive feelings. There is a clear correlation between number of reconstructive surgeries and sexual satisfaction. 90% of patients urinate via catheterization, mostly through a Mitrofanoff connection. This leads to complications such as foul odors, infection, embarrassment and sexual dysfunction. 8 out of 13 men conceived a child (with the use of their own sperm), 2 out of 4 women did. DISCUSSION: A strength of this study is the use of standardized questionnaires which allow comparison to a control patient group. Our study is one of the first to show how patients cope with the challenges of BEEC by the use of open questions. We see an overall high quality of life yet an important impact on mental health. CONCLUSION: BEEC is associated with many challenges in the adult life of patients. A more holistic and interdisciplinary approach is needed to include sensitive topics in long term follow-up.


Assuntos
Extrofia Vesical , Epispadia , Adulto , Criança , Humanos , Masculino , Feminino , Adolescente , Adulto Jovem , Pessoa de Meia-Idade , Epispadia/complicações , Epispadia/cirurgia , Epispadia/psicologia , Extrofia Vesical/complicações , Qualidade de Vida , Sêmen , Fertilidade , Genitália
7.
BMC Med Educ ; 23(1): 64, 2023 Jan 26.
Artigo em Inglês | MEDLINE | ID: mdl-36698177

RESUMO

BACKGROUND: Research suggests that simulation-based surgical skills training translates into improved operating room performance. Previous studies have predominantly focused on training methods and design and subsequent assessable performances and outcomes in the operating room, which only covers some aspects of training engagement and transfer of training. The purpose of this qualitative study was to contribute to the existing body of literature by exploring characteristics of first-year trainees' engagement in and perceptions of transfer of surgical skills training. METHODS: We conducted an explorative study based on individual interviews with first-year trainees in General Surgery, Urology, and Gynaecology and Obstetrics who participated in a laparoscopic skills training program. Informants were interviewed during and two months after the training program. A thematic cross-case analysis was conducted using systematic text condensation. RESULTS: We interviewed 12 informants, which produced 24 transcripts for analysis. We identified four main themes: (1) sportification of training, (2) modes of orientation, (3) transferrable skills, and (4) transfer opportunities. Informants described their surgical training using sports analogies of competition, timing, and step-by-step approaches. Visual orientations, kinaesthetic experiences, and elicited dialogues characterised training processes and engagement. These characteristics were identified in both the simulated and the clinical environment. Experiences of specific skills transfer included ambidexterity, coordination, instrument handling, and visuospatial ability. General transfer experiences were salient in informants' altered training approaches. Informants considered the simulation-based training an entry ticket to perform in the operating room and mentioned supervisor-trainee relationships and opportunities in the workplace as critical conditions of transfer. CONCLUSIONS: Our findings elucidate characteristics of surgical training engagement that can be interpreted as self-regulated learning processes that transcend surgical training environments. Despite appreciating the immediate skills improvements resulting from training, trainees' narratives reflected a struggle to transfer their training to the clinical setting. Tensions existed between perceptions of transferable skills and experiences of transfer within the clinical work environments. These results resonate with research emphasising the importance of the work environment in the transfer process. Our findings provide insights that may inform the development of training programs that support self-regulated learning and transfer of training from the simulated to the clinical environment.


Assuntos
Internato e Residência , Laparoscopia , Feminino , Humanos , Gravidez , Competência Clínica , Simulação por Computador , Educação de Pós-Graduação em Medicina/métodos , Salas Cirúrgicas , Laparoscopia/educação , Cirurgia Geral/educação , Procedimentos Cirúrgicos Obstétricos/educação , Procedimentos Cirúrgicos Urológicos/educação , Procedimentos Cirúrgicos em Ginecologia/educação
8.
Surg Endosc ; 36(2): 1444-1455, 2022 02.
Artigo em Inglês | MEDLINE | ID: mdl-33742271

RESUMO

BACKGROUND: Simulation-based surgical training (SBST) is key to securing future surgical expertise. Proficiency-based training (PBT) in laparoscopy has shown promising results on skills transfer. However, time constraints and limited possibilities for distributed training constitute barriers to effective PBT. Home-based training may provide a solution to these barriers and may be a feasible alternative to centralized training in times of assembly constraints. METHODS: We randomly assigned first-year trainees in abdominal surgery, gynecology, and urology to either centralized instructor-regulated training (CIRT) or home-based self-regulated training (HSRT) in laparoscopy. All participants trained on portable box trainers providing feedback on metrics and possibility for video reviewing. Training in both groups was structured as PBT with graded proficiency exercises adopted from the Fundamentals of Laparoscopic Surgery (FLS). The HSRT group trained at home guided by online learning materials, while the CIRT group attended two training sessions in the simulation center with feedback from experienced instructors. Performance tests consisted of hand-eye and bimanual coordination, suture and knot-tying, and FLS exercises. We analyzed passing rates, training time and distribution, and test performances. RESULTS: Passing rates were 87% and 96% in the CIRT and HSRT group, respectively. HSRT facilitated distributed training and resulted in greater variation in training times. Task times for hand-eye and bimanual coordination were significantly reduced between pretest and posttest in both groups. Trainees maintained their posttest performances at the 6-month retention test. Our analyses revealed no significant inter-group differences in performances at pretest, posttest, or retention test. Performance improvements in the two groups followed similar patterns. CONCLUSION: CIRT and HSRT in laparoscopy result in comparable performance improvements. HSRT in laparoscopy is a feasible and effective alternative to CIRT when offered inside a supportive instructional design. Further research is needed to clarify trainees' preferences and explore facilitators and barriers to HSRT.


Assuntos
Internato e Residência , Laparoscopia , Treinamento por Simulação , Competência Clínica , Currículo , Humanos , Laparoscopia/educação , Treinamento por Simulação/métodos
9.
World J Urol ; 39(4): 1013-1019, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32067073

RESUMO

PURPOSE: To review existing literature about fertility and sexuality of boys born with complex congenital genitourinary anomalies. METHODS: A Pubmed review was performed in December 2018 to identify the most relevant original manuscripts regarding male complex congenital conditions affecting the urogenital system in male patients including spina bifida (SB), bladder exstrophy-epispadias complex (BEEC) and hypospadias. A comprehensive review was drafted exploring sexual dysfunction from a medical, psychosexual, surgical and reproductive point of view during transition from childhood (or adolescence) to adulthood. RESULTS: About 75% of men with SB have erectile dysfunction (ED) (Gamé et al. in Urology 67(3):566-570, 2006; Diamond et al. in 58(4):434-435, 1986). Most SB patients have impaired sexual development mainly due to diminished self-esteem, dependence on caregivers and lack of privacy (Blum et al. in Pediatrics 88(2):280-285, 1991). Men with BEEC have fewer intimate relationships than women because of the greater difficulties with issues regarding their genitalia and sexual activities (Deans et al. in Am J Obstet Gynecol 206(6):496.e1-496.e6, 2012). However, a good quality of life is achievable with the effective use of coping strategies (Deng et al. in Transl Androl Urol 7:941, 2018; Rikken et al. in BMC Womens Health 18(1):163, 2018; Friedler et al. in Reprod Biomed Online 32(1):54-61, 2016). Chordee occurs in 25% of all hypospadias patients. More severe hypospadias is related to a greater risk for complications. The long-term sexual quality of life (QoL) in men who underwent hypospadias surgery is influenced by a lot of factors. Therefore, an interactive and dynamic biopsychosocial model of sexual QoL was proposed. CONCLUSIONS: The care of patients with congenital urologic conditions becomes a challenge especially in the period of 'transition'. The goal of follow-up is a holistic management viewed from a medical, psychosexual, surgical end reproductive point. All patients should be asked for specific urinary, fecal or sexual concerns.


Assuntos
Infertilidade Masculina/etiologia , Disfunções Sexuais Fisiológicas/etiologia , Anormalidades Urogenitais/complicações , Extrofia Vesical/complicações , Epispadia/complicações , Humanos , Hipospadia/complicações , Masculino , Disrafismo Espinal/complicações
10.
Dan Med J ; 67(11)2020 Oct 27.
Artigo em Inglês | MEDLINE | ID: mdl-33215601

RESUMO

INTRODUCTION: Simulation-based surgical training (SBST) is predicated on the assumption that trainees transfer their acquired skills and competencies into the operating room. Research on transfer of surgical training has focused on trainees' performance improvements and not on their actual opportunity to transfer their trained skills. METHODS: This was a retrospective study conducted using data on surgical procedures performed by first-year trainees in abdominal surgery, gynaecology and urology in the Central Denmark Region. We included data on trainees who participated in two different SBST courses; open surgery and laparoscopic surgery from 2014 to 2018. RESULTS: Data on a total of 127 first-year trainees were included. Our results revealed considerable variation in the number of procedures performed by first-year trainees in the three specialities. Comparing surgical activity after and before the SBST courses, we found median differences between 0 and 3, indicating no consistent increases in trainees' surgical activity in the post-course periods (five out of six comparisons were insignificant (p > 0.05)). CONCLUSIONS: Trainees' surgical exposure varies within specialities and this may have consequences for achieving uniform levels of competence among trained specialists. Our results suggest that trainees do not have timely opportunities to intensify their clinical surgical activities after participating in SBST courses. A delay in opportunities to perform may inhibit the trainee's use of acquired skills and competencies and hamper transfer of training. FUNDING: none. TRIAL REGISTRATION: not relevant.


Assuntos
Ginecologia , Laparoscopia , Treinamento por Simulação , Competência Clínica , Ginecologia/educação , Humanos , Estudos Retrospectivos
11.
J Pediatr Urol ; 15(5): 580-581, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31495778

RESUMO

INTRODUCTION: Conventional access for renal surgery through the retro-peritoneum includes the blind percutaneous approach using a haemostatic clip and the Gaur balloon dissection technique or alternatively the open cut-down approach. The authors present a video detailing the technique of optical access into the retro-peritoneum. OBJECTIVE: Demonstration of the optical access technique into the retroperitoneal space using the optical trocar. METHOD: Video describing the technique is carried out. With the patient in the prone position the optical trocar is introduced posteriorly traversing the different layers under vision to safely enter the space just outside gerota's fascia. Blunt dissection with the telescope tip and positive pressure aids creation of the working space. RESULTS: A total of 35 renal surgeries including nephrectomy and nephro-ureterectomy were performed via optical access to the retro-peritoneum. Ages ranged from 6 months to 14 years, and kidney sizes ranged from 1.6 cm to 15 cm, with operating times being 66-137 min. No complications or conversions were encountered. DISCUSSION: Optical access as described previously is achieved with a small incision, with complete control at every stage of the access with no room for error or subjective feeling. At all points, the operator recognises the different layers and is able to predictably reach the right space very quickly and safely. In contrast, the percutaneous technique was blind and the open cut-down required a bigger incision and was practically quite challenging in obese patients with leakage around the port and surgical emphysema. Optical access overcame all these drawbacks and made it reliable, predictable and reproducible. CONCLUSION: Access to the retroperitoneum in the prone posterior approach is achieved safely under vision and is reproducible. Every step in this access is performed in a controlled way and is therefore more predictable as compared to conventional techniques.


Assuntos
Laparoscopia/métodos , Nefrectomia/métodos , Ureter/cirurgia , Adolescente , Criança , Pré-Escolar , Humanos , Lactente , Laparoscopia/instrumentação , Posicionamento do Paciente , Espaço Retroperitoneal , Instrumentos Cirúrgicos
12.
Eur Urol ; 75(6): 1001-1007, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-30935758

RESUMO

CONTEXT: Patients born with complex congenital genitourinary anomalies (including bladder exstrophy, cloacal exstrophy, epispadias, neurogenic bladder, hypospadias and posterior urethral valves) often require major reconstructive surgery in childhood. These conditions, their treatment and sequelae require lifelong follow-up. This has created the need for adult urologists to provide care as these patients grow into adults. OBJECTIVE: To evaluate current strategies for transition and provide a current position statement with examples of the challenges faced by patients and their health care teams as a result of these conditions and their treatment. EVIDENCE ACQUISITION: Each of the authors was asked to provide a 500-word synthesis, based on current literature; to highlight the challenges faced in an area of their expertise. EVIDENCE SYNTHESIS: The authors assembled in March 2018 to form a consensus based on the data gathered. The aforementioned sections were reviewed and following the consensus discussion the paper was formulated and reviewed. CONCLUSIONS: Lifelong care of congenital problems is challenging and essential for many but not all. Expertise is needed to provide the best care for patients and make the best use of resources. Specialist centres appear to be the most effective and safe model. In the long term it would be ideal to establish an evidence base focused on the common long-term problems with these conditions to ensure excellent care with appropriate expertise. PATIENT SUMMARY: Patients born with complex congenital anomalies of the genitourinary system require specialist care in childhood. Many will need lifelong care to manage their condition and the treatment of it. There is growing interest in this area of medicine and this consensus statement addresses the need for lifelong care in this group. The aim is to ensure that all patients that need care at any age are able to find what they need.


Assuntos
Assistência Centrada no Paciente , Procedimentos de Cirurgia Plástica , Transição para Assistência do Adulto , Anormalidades Urogenitais/cirurgia , Urologia , Extrofia Vesical/cirurgia , Epispadia/cirurgia , Feminino , Humanos , Hipospadia/cirurgia , Masculino , Reoperação , Bexiga Urinaria Neurogênica/cirurgia
13.
J Laparoendosc Adv Surg Tech A ; 29(2): 286-291, 2019 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-30358477

RESUMO

OBJECTIVE: Laparoscopy-assisted cutaneous ureterostomy (LA-CU) is a minimally invasive approach for temporary urinary diversion in children. We describe the technique, its feasibility, potential advantages, and outcomes in 12 children treated for a variety of conditions. METHODS: Three trocars were used transperitoneally, one transumbilical, and another placed at the later stoma site. In the semilateral position, with a panoramic view, the ureter of interest is easily identified, mobilized, and exteriorized for stoma creation. We retrospectively reviewed our experience at two tertiary-care centers and included both refluxing and end ureterostomies. The study period was between October 2014 and February 2017. Renal function and growth curves were noted at follow-up. RESULTS: Twelve children underwent LA-CU: 3 end and 9 refluxing ureterostomy. Mean age was 18.75 ± 17.60 months. Mean operating time was 94.44 ± 34.86 minutes. Follow-up ranged from 10 to 38 months. No major postoperative complications occurred. Renal function and growth curves improved in the majority of children. CONCLUSIONS: Primary surgical correction of obstructive or refluxing uropathy is the gold standard; however, temporary urinary diversion is useful in specific scenarios. In these patients, laparoscopic assistance may offer better and direct visualization, achieves accurate and rapid identification of ureter, and provides adequate mobilization, tension-free exteriorization, and excision of redundant ureter in some to optimize drainage. One trocar at the eventual stoma site minimizes scarring.


Assuntos
Laparoscopia , Ureterostomia/métodos , Anormalidades Urogenitais/cirurgia , Doenças Urológicas/cirurgia , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Laparoscopia/efeitos adversos , Masculino , Duração da Cirurgia , Complicações Pós-Operatórias/etiologia , Estudos Retrospectivos , Ureterostomia/efeitos adversos
14.
Acta Chir Belg ; 118(6): 398-401, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30205751

RESUMO

BACKGROUND: Fistula formation in hidradenitis suppurativa follows an uncontrolled infection with subcutaneous tracts leading to 'watering-can' or 'pus-pot' perineum. Closure of this type of fistula implies major surgery and is bound to fail in refractory inflammatory environment. Minimally invasive techniques have become the first line of choice in every type of surgery. METHODS: Fistula-tract Laser Closure (FiLaC™, Biolitec, Germany) is a novel technique already reported to have been used in the treatment of fistula-in-ano and pilonidal sinus. It consists of blind cauterization and obliteration of the fistula tract from the inside by means of a radial-emitting laser probe. We present two patients who underwent surgery for urethroperineal fistula using this technique. RESULTS: In both cases, the fistula tracts were completely closed after 3 months of follow-up. The wounds had healed smoothly and complete resolution of symptoms was noted. CONCLUSIONS: The use of FiLaC™ for the treatment of urethroperineal fistula is feasible and safe. The minimally invasive nature of the technique and limited postoperative pain permit daycare surgery.


Assuntos
Fístula Cutânea/cirurgia , Fístula/etiologia , Terapia a Laser/métodos , Períneo/patologia , Doenças Uretrais/etiologia , Estreitamento Uretral/complicações , Fístula Cutânea/etiologia , Fístula/cirurgia , Hidradenite Supurativa/complicações , Hidradenite Supurativa/diagnóstico , Humanos , Terapia a Laser/instrumentação , Imageamento por Ressonância Magnética/métodos , Masculino , Pessoa de Meia-Idade , Períneo/cirurgia , Prognóstico , Medição de Risco , Resultado do Tratamento , Doenças Uretrais/cirurgia , Estreitamento Uretral/cirurgia , Técnicas de Fechamento de Ferimentos/instrumentação , Cicatrização/fisiologia
15.
BJU Int ; 122(4): 654-666, 2018 10.
Artigo em Inglês | MEDLINE | ID: mdl-29461677

RESUMO

OBJECTIVES: To assess the presence of testicular asymmetry and the currently used threshold values in varicocoele management in a healthy adolescent population. SUBJECTS AND METHODS: We conducted an observational cross-sectional study from April 2015 until December 2016 in which we recruited 539 adolescent boys aged 11-16 years. A clinical examination including testicular size measurement by ultrasonography was performed. Testicular volume (TV) was calculated using the Lambert formula (length × width × height × 0.71). The Testicular Atrophy Index (TAI) was calculated using the formula [(TV right - TV left)/largest TV] × 100. The data for all statistical analyses were stratified for Tanner stage for genital development (TSG) and pubic hair (TSP). Non-parametric tests were used to assess the difference between right and left TV, and the prevalence of a smaller left testis for the entire population, and between each TSG and TSP. Parametric tests were used to determine the difference in mean TAI between each TSG and TSP, and to compare the mean TAI to a test value of 0. RESULTS: Of the 539 recruited boys, we excluded 194 due to a current or past pathology, including varicocoeles, influencing normal (testicular) growth or due to incomplete data. Most boys were in the second Tanner stage, followed by the third Tanner stage. The mean (sd) age of the entire population was 13.33 (1.25) years. Of the 345 included participants the mean (sd) left TV was 7.67 (5.63) mL and right TV was 7.97 (5.90) mL. The mean (sd) TAI was 2.85 (17.00)%. In all, 203 (58.84%) boys had a smaller left testis and 142 (41.16%) had a smaller right testis. In all, 51 boys (14.78%) had a TAI >20%, 45 (13.04%) had a TV difference (TVD) of >2 mL with a deficit in left TV, and 69 (20.00)% had a TAI >20% or a TVD of >2 mL with a deficit in left TV. Related-samples Wilcoxon signed-rank test showed a significant difference in mean left and right TV for the entire population, and more specifically for TSG3 (P < 0.001) and TSP3 (P = 0.004). A one-sample t-test showed a significant difference in the mean TAI vs the test value of 0 for the entire population (P = 0.002), and more specifically for TSG3 (P < 0.001) and TSP3 (P = 0.003). CONCLUSION: Testicular asymmetry, with a smaller left testis, was seen in a considerable number of healthy adolescents. One out of five adolescents had a smaller left testis and met one of the threshold values currently used in varicocoele management. Therefore, in left-sided unilateral inguinoscrotal pathology, a smaller ipsilateral testis in combination with a TAI of >20% and/or TVD of >2 mL requires careful interpretation and serial measurements of TV should always be performed. Furthermore, this study provides reference values for TV, TVD and TAI according to TSG and TSP for a healthy adolescent population.


Assuntos
Atrofia/diagnóstico , Tamanho do Órgão/fisiologia , Testículo/anatomia & histologia , Varicocele/diagnóstico , Adolescente , Criança , Estudos Transversais , Humanos , Masculino , Valores de Referência , Estudos Retrospectivos , Testículo/patologia
16.
J Pediatr Urol ; 11(5): 283-4, 2015 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-26068000

RESUMO

OBJECTIVE: We have previously reported our early experience (2 patients) of single-incision nephrectomy via the retroperitoneal prone route using an advanced access platform (GelPOINT Mini). Here, we review our series to date and also present a detailed video demonstrating the technique. METHOD: In the prone position, a single transverse incision was made at the midpoint on a line along the lateral border of erector spinae bounded by the lower border of the 12th rib and iliac crest. Posterior abdominal muscles were split and the deep lumbodorsal fascia incised. The Alexis retractor was positioned and the Gel-Seal cap with low-profile sleeves locked in place. Hilar vessels were divided by endoclip application or harmonic scalpel. The kidney was retrieved directly or via an endobag. The Alexis retractor was removed and wound closed with absorbable sutures. RESULTS: Between July 2013 and March 2015, we have used this approach to perform 10 nephrectomies in nine patients (4 male and 5 female). The median age at nephrectomy was 10.9 years (range 2.7-15.9 years). The median kidney length was 7.5 cm (range 3.7-11.5 cm). No complications occurred and none converted to open procedure. CONCLUSION: Single incision retroperitoneal nephrectomy is feasible, safe, and provides excellent cosmesis.


Assuntos
Nefropatias/cirurgia , Laparoscopia/métodos , Nefrectomia/métodos , Decúbito Ventral , Espaço Retroperitoneal/cirurgia , Adolescente , Criança , Pré-Escolar , Estudos de Viabilidade , Feminino , Humanos , Tempo de Internação/tendências , Masculino , Estudos Retrospectivos
18.
Adv Med Educ Pract ; 6: 55-63, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25674032

RESUMO

BACKGROUND: The purpose of this study was to investigate the exposure of Belgian residents in urology, general surgery, and gynecology to laparoscopic surgery and to training of laparoscopic skills in dedicated training facilities. METHODS: Three similar specialty-specific questionnaires were used to interrogate trainees in urology, general surgery, and gynecology about their exposure to laparoscopic procedures, their acquired laparoscopic experience, training patterns, training facilities, and motivation. Residents were contacted via their Belgian specialist training organization, using Survey Monkey as an online survey tool. Data were analyzed with descriptive statistics. RESULTS: The global response rate was 58%. Only 28.8% of gynecology respondents, 26.9% of urology respondents, and 52.2% of general surgery respondents felt they would be able to perform laparoscopy once they had finished their training. A total 47% of urology respondents, 66.7% of general surgery respondents, and 69.2% of gynecology respondents had a surgical skills lab that included laparoscopy within their training hospital or university. Most training programs did not follow the current evidence about proficiency-based structured simulation training with deliberate practice. CONCLUSION: Belgian resident training facilities for laparoscopic surgery should be optimized.

19.
Int J Clin Pharm ; 37(2): 379-86, 2015 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-25666940

RESUMO

BACKGROUND: In Europe, parenteral nutrition is often used after radical cystectomy to avoid postoperative malnourishment. To the best of our knowledge, however, there is a paucity of data to conclude on the best modality for delivering nutritional support to this patient group. OBJECTIVE: The parenteral nutrition policy was reconsidered and an oral nutrition protocol was implemented by the clinical pharmacist and evaluated in terms of length of stay, number and type of postoperative complications and parenteral nutrition avoided costs. SETTING: A prospective interventional non-randomized before-after study was conducted. Regular radical cystectomy patients presenting without preoperative contra-indications for enteral nutrition were eligible. METHODS: Postoperatively, in the control group, the parenteral nutrition policy from the ward was applied. Parenteral nutrition was initiated systematically and continued until the patient was able to tolerate solid food. In the interventional group, an oral nutrition protocol was implemented. Parenteral nutrition could be initiated if oral intake remained insufficient after 5 days. Main outcome measure The primary end point was postoperative length of stay. Secondary endpoints included the number of patients in whom the oral nutrition protocol was implemented successfully, as well as the number and type of postoperative complications. RESULTS: A total of 94 eligible patients was assigned consecutively to the control (n = 48) and to the interventional group (n = 46). Baseline demographics were comparable. A significant reduction in median length of stay was associated with the oral nutrition protocol [18 days (IQR 15-22) in the control group vs. 14 days (IQR 13-18) in the interventional group (p < 0.001)]. In 40 out of 46 patients from the interventional group, the oral nutrition protocol was implemented successfully. The number and type of postoperative complications did not differ significantly. Implementing the oral nutrition protocol resulted in a direct parenteral nutrition infusion bag cost saving of approximately €512 and a reduction in hospitalization cost of €2,608 per patient. CONCLUSION: The findings of our study showed that an oral nutrition protocol, when compared to the systematic postoperative use of parenteral nutrition, was associated with a decreased length of stay and costs in a regular radical cystectomy patient population.


Assuntos
Cistectomia , Nutrição Enteral/métodos , Tempo de Internação , Nutrição Parenteral/métodos , Cuidados Pós-Operatórios/métodos , Idoso , Cistectomia/tendências , Nutrição Enteral/tendências , Feminino , Seguimentos , Humanos , Tempo de Internação/tendências , Masculino , Pessoa de Meia-Idade , Nutrição Parenteral/tendências , Cuidados Pós-Operatórios/tendências , Estudos Prospectivos , Resultado do Tratamento
20.
J Surg Educ ; 72(3): 483-90, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25555673

RESUMO

OBJECTIVES: As conventional laparoscopic procedural training requires live animals or cadaver organs, virtual simulation seems an attractive alternative. Therefore, we compared the transfer of training for the laparoscopic cholecystectomy from porcine cadaver organs vs virtual simulation to surgery in a live animal model in a prospective randomized trial. DESIGN: After completing an intensive training in basic laparoscopic skills, 3 groups of 10 participants proceeded with no additional training (control group), 5 hours of cholecystectomy training on cadaver organs (= organ training) or proficiency-based cholecystectomy training on the LapMentor (= virtual-reality training). Participants were evaluated on time and quality during a laparoscopic cholecystectomy on a live anaesthetized pig at baseline, 1 week (= post) and 4 months (= retention) after training. SETTING: All research was performed in the Center for Surgical Technologies, Leuven, Belgium. PARTICIPANTS: In total, 30 volunteering medical students without prior experience in laparoscopy or minimally invasive surgery from the University of Leuven (Belgium). RESULTS: The organ training group performed the procedure significantly faster than the virtual trainer and borderline significantly faster than control group at posttesting. Only 1 of 3 expert raters suggested significantly better quality of performance of the organ training group compared with both the other groups at posttesting (p < 0.01). There were no significant differences between groups at retention testing. The virtual trainer group did not outperform the control group at any time. CONCLUSIONS: For trainees who are proficient in basic laparoscopic skills, the long-term advantage of additional procedural training, especially on a virtual but also on the conventional organ training model, remains to be proven.


Assuntos
Colecistectomia Laparoscópica/educação , Educação de Graduação em Medicina/métodos , Treinamento por Simulação , Animais , Bélgica , Cadáver , Competência Clínica , Instrução por Computador , Avaliação Educacional , Humanos , Modelos Animais , Estudos Prospectivos , Suínos , Interface Usuário-Computador
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