Assuntos
Anticorpos Anti-Hepatite B/sangue , Vacinas contra Hepatite B/imunologia , Recursos Humanos em Hospital , Vacinação , Adulto , Feminino , Hepatite B/prevenção & controle , Anticorpos Anti-Hepatite B/biossíntese , Antígenos de Superfície da Hepatite B/imunologia , Humanos , Esquemas de Imunização , Masculino , México , Doenças Profissionais/prevenção & controle , Fumar/imunologia , Vacinas Sintéticas/imunologiaAssuntos
Adulto , Feminino , Humanos , Masculino , Anticorpos Anti-Hepatite B/sangue , Vacinas contra Hepatite B/imunologia , Recursos Humanos em Hospital , Vacinação , Anticorpos Anti-Hepatite B/biossíntese , Antígenos de Superfície da Hepatite B/imunologia , Hepatite B/prevenção & controle , Esquemas de Imunização , México , Doenças Profissionais/prevenção & controle , Fumar/imunologia , Vacinas Sintéticas/imunologiaRESUMO
The objective of this study was to assess the functional capacity for intracellular death (ID) and/or phagocytic index (PI) of polymorphonuclear cells of 24-h-old healthy newborns with respect to the PMN cells of adults using the same standard exogenous source of opsonins. The ID and PI techniques were standardized and 2-3 ml of blood were used. No differences were found in the percentages of ID, P, PI among the PMNs of the newborns and those of the adults: 43.95 +/- 15.70 vs. 44.56 +/- 8.43 for ID; 38.96 +/- 14.34 vs. 39.00 +/- 14.54 for P; 1.71 +/- 0.54 vs. 1.73 0.45 for PI, respectively. It was concluded that the PMNs of 24-h newborns have an ID, P, PI functionality comparable to adult PMNs; differences observed in PMN function in newborns may be due to humoral deficiencies (opsonins).