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Biochem Genet ; 27(7-8): 451-67, 1989 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-2619707

RESUMO

Four samples of the mussel Mytilus edulis were taken between 1984 and 1987 from Stony Brook, New York, and used to study the glucose-6-phosphate isomerase (GPI) polymorphism in this species. In vitro specific activity and in vivo flux measured in the same animals were found to be significantly correlated. A significant effect of GPI genotype on flux was observed in one of the samples; overall, significant evidence of effect of genotype on enzyme activity was also obtained. GPI activities of common genotypes tend to deviate less from the population mean than those of rare (frequency less than 5%) genotypes. This suggests the possibility that rare GPI genotypes are rare as a consequence of having biochemical properties that deviate from an optimum level and, therefore, having a lower fitness. In support of this hypothesis, we found in one of our samples that shell length is a concave function of GPI activity with an intermediate optimum activity level.


Assuntos
Bivalves/genética , Glucose-6-Fosfato Isomerase/genética , Análise de Variância , Animais , Bivalves/enzimologia , Frequência do Gene , Genótipo , Glucose-6-Fosfato Isomerase/metabolismo , Fenótipo , Polimorfismo Genético , Temperatura
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