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1.
Comput Biol Med ; 173: 108303, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38547653

RESUMO

The rising occurrence and notable public health consequences of skin cancer, especially of the most challenging form known as melanoma, have created an urgent demand for more advanced approaches to disease management. The integration of modern computer vision methods into clinical procedures offers the potential for enhancing the detection of skin cancer . The UNet model has gained prominence as a valuable tool for this objective, continuously evolving to tackle the difficulties associated with the inherent diversity of dermatological images. These challenges stem from diverse medical origins and are further complicated by variations in lighting, patient characteristics, and hair density. In this work, we present an innovative end-to-end trainable network crafted for the segmentation of skin cancer . This network comprises an encoder-decoder architecture, a novel feature extraction block, and a densely connected multi-rate Atrous convolution block. We evaluated the performance of the proposed lightweight skin cancer segmentation network (LSCS-Net) on three widely used benchmark datasets for skin lesion segmentation: ISIC 2016, ISIC 2017, and ISIC 2018. The generalization capabilities of LSCS-Net are testified by the excellent performance on breast cancer and thyroid nodule segmentation datasets. The empirical findings confirm that LSCS-net attains state-of-the-art results, as demonstrated by a significantly elevated Jaccard index.


Assuntos
Neoplasias da Mama , Melanoma , Neoplasias Cutâneas , Humanos , Feminino , Neoplasias Cutâneas/diagnóstico por imagem , Melanoma/diagnóstico por imagem , Benchmarking , Cabelo , Processamento de Imagem Assistida por Computador
2.
Med Biol Eng Comput ; 62(5): 1491-1501, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38300437

RESUMO

Cancer is an invasive and malignant growth of cells and is known to be one of the most fatal diseases. Its early detection is essential for decreasing the mortality rate and increasing the probability of survival. This study presents an efficient machine learning approach based on the state vector machine (SVM) to diagnose and classify tumors into malignant or benign cancer using the online lymphographic data. Further, two types of neural network architectures are also implemented to evaluate the performance of the proposed SVM-based approach. The optimal structures of the classifiers are obtained by varying the architecture, topology, learning rate, and kernel function and recording the results' accuracy. The classifiers are trained with the preprocessed data examples after noise removal and tested on the unknown cases to diagnose each example as positive or negative. Further, the positive cases are classified into different stages including metastases, malign lymph, and fibrosis. The results are evaluated against the feed-forward and generalized regression neural networks. It is found that the proposed SVM-based approach significantly improves the early detection and classification accuracy in comparison to the experienced physicians and the other machine learning approaches. The proposed approach is robust and can perform sub-class divisions for multipurpose tasks. Experimental results demonstrate that the two-class SVM gives the best results and can effectively be used for the classification of cancer. It has outperformed all other classifiers with an average accuracy of 94.90%.


Assuntos
Neoplasias , Máquina de Vetores de Suporte , Algoritmos , Redes Neurais de Computação , Aprendizado de Máquina , Probabilidade , Neoplasias/diagnóstico
3.
Cancers (Basel) ; 14(21)2022 Nov 06.
Artigo em Inglês | MEDLINE | ID: mdl-36358875

RESUMO

The diagnosis of early-stage lung cancer is challenging due to its asymptomatic nature, especially given the repeated radiation exposure and high cost of computed tomography(CT). Examining the lung CT images to detect pulmonary nodules, especially the cell lung cancer lesions, is also tedious and prone to errors even by a specialist. This study proposes a cancer diagnostic model based on a deep learning-enabled support vector machine (SVM). The proposed computer-aided design (CAD) model identifies the physiological and pathological changes in the soft tissues of the cross-section in lung cancer lesions. The model is first trained to recognize lung cancer by measuring and comparing the selected profile values in CT images obtained from patients and control patients at their diagnosis. Then, the model is tested and validated using the CT scans of both patients and control patients that are not shown in the training phase. The study investigates 888 annotated CT scans from the publicly available LIDC/IDRI database. The proposed deep learning-assisted SVM-based model yields 94% accuracy for pulmonary nodule detection representing early-stage lung cancer. It is found superior to other existing methods including complex deep learning, simple machine learning, and the hybrid techniques used on lung CT images for nodule detection. Experimental results demonstrate that the proposed approach can greatly assist radiologists in detecting early lung cancer and facilitating the timely management of patients.

4.
Comput Biol Med ; 145: 105425, 2022 06.
Artigo em Inglês | MEDLINE | ID: mdl-35398808

RESUMO

A suitable temporal and spectral processing of the electrocardiogram (ECG) signals can facilitate the visual interpretation and discrimination between known patterns for classification. This paper proposes a non-invasive hybrid neural network and time-frequency (TF) based method to detect and classify commonly found cardiac abnormalities in ECG signals including congestive heart failure, ventricular tachyarrhythmia, intracardiac atrial fibrillation, arrhythmia, malignant ventricular ectopy, normal sinus rhythm, and postictal heart rate oscillations in partial epilepsy. Non-stationary raw ECG signals are collected from an online healthcare dataset source 'PhysioBank' that contains physiologic signals. These temporal signals are processed through Wigner-Ville distribution to produce high-resolution and concentrated TF images depicting specific visual patterns of cardiac abnormalities. The TF images are used to extract the abnormality parameters with the help of medical experts with good diagnostic accuracy. Principal component analysis (PCA) is employed for feature reduction and important features selection from the ECG signals. The selected features are used for training the multilayer feed-forward artificial neural network (ANN) for detection and classification while training parameters like the number of epochs, activation functions, and the learning rate is suitably selected with appropriate stopping criteria. Experimental results demonstrate the effectiveness of the hybrid neural-TF approach using PCA for abnormality detection and classification.


Assuntos
Fibrilação Atrial , Cardiopatias Congênitas , Algoritmos , Fibrilação Atrial/diagnóstico , Eletrocardiografia , Coração , Frequência Cardíaca , Humanos , Redes Neurais de Computação , Processamento de Sinais Assistido por Computador
5.
Big Data ; 2022 Apr 04.
Artigo em Inglês | MEDLINE | ID: mdl-35377193

RESUMO

Wireless in vivo actuators and sensors are examples of sophisticated technologies. Another breakthrough is the use of in vivo wireless medical devices, which provide scalable and cost-effective solutions for wearable device integration. In vivo wireless body area networks devices reduce surgery invasiveness and provide continuous health monitoring. Also, patient data may be collected over a long period of time. Given the large fading in in vivo channels due to the signal path going through flesh, bones, skins, and blood, channel coding is considered a solution for increasing the efficiency and overcoming inter-symbol interference in wireless communications. Simulations are performed by using 50 MHz bandwidth at Ultra-Wideband frequencies (3.10-10.60 GHz). Optimal channel coding (Turbo codes, Convolutional codes, with the help of polar codes) improves data transmission performance over the in vivo channel in this research. Moreover, the results reveal that turbo codes outperform polar and convolutional codes in terms of bit error rate. Other approaches perform similarly when the information block length is increased. The simulation in this work indicates that the in vivo channel shows less performance than the Rayleigh channel due to the dense structure of the human body (flesh, skins, blood, bones, muscles, and fat).

6.
Cureus ; 11(2): e4069, 2019 Feb 13.
Artigo em Inglês | MEDLINE | ID: mdl-31016096

RESUMO

BACKGROUND: The levels of adenosine deaminase (ADA) are increased in tubercular pleural effusion and its determination has acquired popularity as a diagnostic test which is inexpensive and is readily accessible. Pleural fluid ADA showed sensitivity (86.36%), specificity (61.54%), diagnostic accuracy (80.70%), positive predictive value (88.37%), and negative predictive value (82.42%) confirmed by pleural biopsy as a gold standard. METHODOLOGY: Our study was a prospective cross-sectional study which was conducted for three years at a tertiary care center in Karachi, Pakistan. The data were collected and analyzed using IBM statistics SPSS vs21. RESULTS: There were 52 patients included in our study. Twenty one were males and thirty one were females. Most patients presented with shortness of breath. There was a significant association found between raised ADA levels and pulmonary tuberculosis (p < 0.05). The ADA levels are 12 times more likely to be raised in tubercular pleural effusion. CONCLUSION: The ADA level is an important marker for diagnosis of pulmonary tuberculosis in lymphocytic pleural effusion. It is a convenient and an inexpensive method. The ADA levels assessment is economical when compared to other diagnostic methods.

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