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Angiology ; 59(1): 77-83, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-18319226

RESUMO

Lymphedema is mainly characterized by swelling, fibrosis, and non-pitting edema. The aim of this study was evaluation of the long-term (10 years) effects of autologous lymphatic tissue implant in lymphedema. Lymphatic tissue from 9 patients (harvested form the same patient in areas not affected by lymphedema) was reimplanted into the affected limb, and these patients were followed for 10 years. Lymph nodes were harvested at the neck, axillary, or inguinal space (contralateral limb). Results showed that limb volume was decreased in the treatment group vs. controls. In ultrasound, black, low density, lymphatic spaces were visible in 100% of patients at inclusion but in only 23% of these subjects at 10 years. Thus, this early report proposes a new, minimally invasive method to improve lymphedema. Studies in progress will indicate the role of lymphatic transplant in the management of lymphedema and the best indications for this method.


Assuntos
Linfedema/cirurgia , Tecido Linfoide/transplante , Adulto , Índice de Massa Corporal , Líquido Extracelular/metabolismo , Feminino , Seguimentos , Custos de Cuidados de Saúde , Humanos , Linfedema/diagnóstico por imagem , Linfedema/etiologia , Linfedema/metabolismo , Linfedema/patologia , Masculino , Pessoa de Meia-Idade , Procedimentos Cirúrgicos Minimamente Invasivos/efeitos adversos , Procedimentos Cirúrgicos Minimamente Invasivos/economia , Cooperação do Paciente , Projetos Piloto , Proteínas/metabolismo , Índice de Gravidade de Doença , Pele/patologia , Fatores de Tempo , Transplante Autólogo/efeitos adversos , Transplante Autólogo/economia , Resultado do Tratamento , Ultrassonografia
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