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Prog Urol ; 33(3): 125-134, 2023 Mar.
Artigo em Francês | MEDLINE | ID: mdl-36604247

RESUMO

INTRODUCTION: Restaging transurethral resection (re-TUR) of high grade T1 bladder cancer (HGT1-BC) is recommended but the impact in terms of recurrence-free survival (RFS) and progression-free survival (PFS) is discussed. The objective of this study was to evaluate our practice of re-TUR for these tumors and its impact on overall survival (OS), RFS and PFS. MATERIALS AND METHODS: A retrospective observational study was conducted between 2010 and 2020. The inclusion criteria was the presence of newly diagnosed HGT1-BC. Patients with incomplete resection, suspicion of infiltrating tumor, upper tract urothelial cancer, or metastatic disease were ineligible. Two groups were defined : Group 1 with re-TUR and Group 2 without re-TUR. RFS and PFS were evaluated. RESULTS: A total of 78 patients were included, including 50 (64,1%) in group 1. There were no significant differences between the two groups. The mean time to re-TUR was 8 weeks and 60% residual tumor was found. Initial under-staging was found in 12% of cases. RFS and PFS were significantly better in Group 1 (P=0.0019; P=0,02). No significant were found between the groups in OS and specific survival (SS). CONCLUSION: Performing a re-TUR for high grade T1 bladder tumors allows detection of residual tumor and decreases the risk of under-evaluation. It is associated with a significant improvement in RFS and PFS with no impact on OS and SS.


Assuntos
Neoplasias da Bexiga Urinária , Bexiga Urinária , Humanos , Intervalo Livre de Progressão , Neoplasia Residual/patologia , Neoplasia Residual/cirurgia , Estadiamento de Neoplasias , Bexiga Urinária/patologia , Neoplasias da Bexiga Urinária/patologia , Estudos Retrospectivos , Recidiva Local de Neoplasia/cirurgia , Cistectomia
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