Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 30
Filtrar
1.
Pediatr Radiol ; 42(4): 488-90, 2012 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22002842

RESUMO

Walker-Warburg syndrome (WWS) is a rare, lethal autosomal recessive disorder characterized by congenital muscular dystrophy and brain and eye anomalies. A prenatal finding of hydrocephalus associated with posterior fossa anomalies and/or encephalocele is nonspecific, whereas additional ocular anomalies are typical for WWS. We report a fetus of consanguineous parents found to have encephalocele at US in week 15 of gestation. The parents did not wish to terminate the pregnancy. Follow-up US revealed bilateral abnormal ocular echoic structures suggesting a major form of persistent primary vitreous. WWS was suspected. The POMT2 mutation confirmed this diagnosis. In hydrocephalus associated with posterior fossa anomalies and/or encephalocele, we recommend detailed US examination of the fetal eyes. Ocular anomalies in this context strongly suggest WWS.


Assuntos
Descolamento Retiniano/congênito , Descolamento Retiniano/diagnóstico por imagem , Ultrassonografia Pré-Natal/métodos , Síndrome de Walker-Warburg/diagnóstico por imagem , Síndrome de Walker-Warburg/embriologia , Humanos
2.
Ultrasound Obstet Gynecol ; 38(5): 543-7, 2011 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-22028043

RESUMO

OBJECTIVES: To determine whether there is an association between the fetal ultrasound finding of hyperechoic colon and the gestational age at which it presents and cystinuria. METHODS: A prospective national survey was performed in France including all observations of isolated fetal hyperechoic colon detected at routine second- and third-trimester ultrasound over a 2-year period. Collected images were reviewed by experts. Colon was defined as being hyperechoic when its echogenicity was at least equal to that of the iliac bone. It was diagnosed when large tubular echogenic portions of the colon, without a focal mass and without posterior acoustic shadows, were observed at the periphery of the abdomen. Urinary amino acid analysis was performed after birth in the cases identified to test for cystinuria. RESULTS: Nineteen fetuses with ultrasound findings of hyperechoic colon were included, and the mothers of 16 of these agreed to participate in the study. In eight of nine cases of hyperechoic colon observed before 36 weeks' gestation cystinuria was confirmed at birth. In the seven remaining cases, observed after 36 weeks, none was found to have cystinuria and all had normal images at previous routine ultrasound scans at 22 and 33 weeks. When present, no difference in the sonographic appearance of hyperechoic colon was noted between the two groups. In the cystinuria-affected cases, the length of the hyperechoic mass appeared to increase with gestational age. CONCLUSIONS: In our experience, the presence of a hyperechoic colon at routine ultrasound scan before 36 weeks' gestation should prompt screening for cystinuria at birth, while later observation (> 36 weeks) of this finding does not appear to be related to any disease.


Assuntos
Aminoácidos/urina , Colo/diagnóstico por imagem , Cistinúria/diagnóstico por imagem , Doenças Fetais/diagnóstico por imagem , Ultrassonografia Pré-Natal , Adulto , Colo/anormalidades , Colo/embriologia , Cistinúria/embriologia , Cistinúria/urina , Feminino , Doenças Fetais/urina , França , Idade Gestacional , Humanos , Recém-Nascido , Masculino , Gravidez , Estudos Prospectivos
3.
Eur Radiol ; 18(10): 2060-6, 2008 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-18458906

RESUMO

Fetal intracranial tumors are rare. The diagnosis is generally made on histology after birth. The aim of this study was to analyze clinical and imaging data in a series of fetal intracranial tumors and emphasize the findings that may help approach the diagnosis antenatally. We retrospectively analyzed imaging and clinical findings in 27 cases of fetal intracranial tumors assessed by ultrasound (27/27) and MR imaging (24/27). A histological diagnosis was always obtained. Main diagnoses included 15 germinal tumors (13 teratomas), 4 glial tumors, 2 craniopharyngiomas and 3 hamartomas. Average gestational age at diagnosis was 27 weeks for teratomas, 21 weeks for hamartomas and 34 weeks for glial tumors. All tumors but one were supra tentorial, and the lesion extended in the posterior fossa in two teratomas. A heterogeneous pattern, which was more frequently seen in teratomas, was better visualized by MR than US imaging. In addition, in two cases of teratomas, MR imaging better assessed the extension of the tumor. Teratomas and gliomas are the most frequent brain tumors in the fetus. US and MR imagings appear complementary in the prenatal assessment of these lesions.


Assuntos
Neoplasias Encefálicas/diagnóstico , Neoplasias Encefálicas/embriologia , Doenças Fetais/diagnóstico , Imageamento por Ressonância Magnética/métodos , Ultrassonografia Pré-Natal/métodos , Feminino , Humanos , Masculino , Estudos Retrospectivos
4.
Acta Paediatr ; 97(4): 420-4, 2008 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-18307547

RESUMO

AIM: To evaluate long-term neurodevelopmental outcomes in children with prenatally diagnosed, isolated agenesis of the corpus callosum (ACC). METHODS: We retrospectively reviewed data for 20 children born between January 1991 and November 2003 in the Haute-Normandie region of France with a prenatal diagnosis of isolated ACC. We collected data on pre-and postnatal neuroimaging findings, clinical features at birth and neurodevelopmental outcomes. RESULTS: Follow-up ranged from 3 to 16 years. ACC was complete in 11 patients (55%), partial in 2 (10%), hypoplastic in 3 (15%) and associated with an interhemispheric cyst in 4 (20%). Neurodevelopmental outcome was normal in 11 (55%) patients, including 8 with complete ACC; moderate disability was present in 5 (25%) patients and severe disability in 4 (20%) patients. In 3 of the 4 patients with severe disability, postnatal cerebral magnetic resonance imaging (MRI) showed additional major cerebral abnormalities. CONCLUSION: Neurodevelopmental outcome was good in most of our patients with isolated ACC, with 80% of patients having normal outcomes or moderate disabilities. A prenatal diagnosis of isolated ACC may not warrant termination of pregnancy. A carefully interpreted prenatal cerebral MRI is crucial to detect associated cerebral abnormalities; a longer follow-up is necessary to look for moderate disabilities.


Assuntos
Agenesia do Corpo Caloso , Deficiências do Desenvolvimento/epidemiologia , Doenças do Sistema Nervoso/epidemiologia , Ultrassonografia Pré-Natal , Criança , Pré-Escolar , Seguimentos , Humanos , Inteligência , Imageamento por Ressonância Magnética
5.
Gynecol Obstet Fertil ; 35(10): 1001-4, 2007 Oct.
Artigo em Francês | MEDLINE | ID: mdl-17921039

RESUMO

Sacrococcygeal teratoma is the most common and benign fetal tumor. Fetuses with sacrococcygeal tumors that are predominantly solid and highly vascularized have a high risk of fatal issue. Hydrops and tumor hemorrhage are associated with a highest risk of fetal death. Management of these tumors includes ultrasound scan with Doppler and magnetic resonance imaging (MRI) is usually used for evaluation of its intrapelvic extension and relationship to the other structures. New in-utero treatments as vascular coagulation have been applied in fetuses with highly vascular teratomas but these techniques are still experimental and need more investigations. The management of delivery depends on associated anomalies, tumor vascularity and size.


Assuntos
Parto Obstétrico , Doenças Fetais/diagnóstico , Diagnóstico Pré-Natal , Região Sacrococcígea/patologia , Teratoma/embriologia , Deleção Cromossômica , Cromossomos Humanos Par 1 , Cromossomos Humanos Par 7 , Feminino , Humanos , Recém-Nascido , Cariotipagem , Imageamento por Ressonância Magnética , Poli-Hidrâmnios/patologia , Gravidez , Teratoma/diagnóstico por imagem , Teratoma/genética , Teratoma/patologia , Trissomia , Ultrassonografia
6.
J Radiol ; 88(2): 269-76, 2007 Feb.
Artigo em Francês | MEDLINE | ID: mdl-17372555

RESUMO

OBJECTIVE: Evaluate the advantages of color Doppler and pulsed Doppler in the diagnosis and prognosis of fetal pulmonary malformations. MATERIALS AND METHOD: This retrospective study of 24 fetuses explored pulmonary malformations using sonography. A classification into four groups was made based on the presence of cysts and the echogenicity of the lesion, then analysis of video recordings including Doppler with an interpretation chart: afferent vessel, color chart, spectrum shape (afferent vessel and within the malformation) to determine the contribution of Doppler within each group. RESULTS: Four lesions were avascular: bronchogenic cysts (three cases), subphrenic sequestration (one case). The other lesions were vascularized and color Doppler determined the source of vascularization feeding the malformation: branches of the pulmonary artery in 13 cases (eight cases of cystic adenomatoid disease, two cases of atresia, and three airway obstacles) or the aorta in seven cases (pulmonary sequestrations) with pulmonary venous return, six cases (intralobular sequestrations), or systemic venous return, one case (extralobular sequestration). The pulsed Doppler recording in the malformation (six cases) completed the color Doppler examination by showing the different spectrum shapes according to the aortic or pulmonary source of flow. The color chart matched in three cases (normal pulmonary segmentation) and was heterogeneous in eight cases (parenchymatous dysplasia). Furthermore, perfusion intensity was correlated with lesion progression. CONCLUSION: Color Doppler and pulsed Doppler provided a more precise diagnosis of these malformations and seems to contribute prognostic information.


Assuntos
Pulmão/anormalidades , Pulmão/diagnóstico por imagem , Ultrassonografia Doppler de Pulso , Ultrassonografia Pré-Natal , Feminino , Humanos , Gravidez , Estudos Retrospectivos
7.
BJOG ; 114(3): 310-8, 2007 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-17169012

RESUMO

OBJECTIVE: To evaluate whether magnesium sulphate (MgSO(4)) given to women at risk of very-preterm birth would be neuroprotective in preterm newborns and would prevent neonatal mortality and severe white-matter injury (WMI). DESIGN: A randomised study. SETTING: Eighteen French tertiary hospitals. Population Women with fetuses of gestational age < 33 weeks whose birth was planned or expected within 24 hours were enrolled from July 1997 to July 2003 with follow up of infants until hospital discharge. METHODS Five hundred and seventy-three mothers were randomly assigned to receive a single 40-ml infusion of 0.1 g/ml of MgSO(4) (4 g) solution or isotonic 0.9% saline (placebo) over 30 minutes. This study is registered as an International Standard Randomised Controlled Trial, number 00120588. MAIN OUTCOME MEASURES: The primary endpoints were rates of severe WMI or total mortality before hospital discharge, and their combined outcome. Analyses were based on intention to treat. RESULTS: After 6 years of enrolment, the trial was stopped. Data from 688 infants were analysed. Comparing infants who received MgSO(4) or placebo, respectively, total mortality (9.4 versus 10.4%; OR: 0.79, 95% CI 0.44-1.44), severe WMI (10.0 versus 11.7%; OR: 0.78, 95% CI 0.47-1.31) and their combined outcomes (16.5 versus 17.9%; OR: 0.86, 95% CI 0.55-1.34) were less frequent for the former, but these differences were not statistically significant. No major maternal adverse effects were observed in the MgSO(4) group. CONCLUSION: Although our results are inconclusive, improvements of neonatal outcome obtained with MgSO(4) are of potential clinical significance. More research is needed to assess the protective effect of MgSO(4) alone or in combination with other neuroprotective molecules.


Assuntos
Paralisia Cerebral/prevenção & controle , Leucomalácia Periventricular/prevenção & controle , Sulfato de Magnésio/administração & dosagem , Trabalho de Parto Prematuro/prevenção & controle , Tocolíticos/administração & dosagem , Adulto , Paralisia Cerebral/mortalidade , Feminino , Humanos , Mortalidade Infantil , Recém-Nascido , Recém-Nascido Prematuro , Infusões Intravenosas , Leucomalácia Periventricular/mortalidade , Sulfato de Magnésio/efeitos adversos , Gravidez , Resultado da Gravidez , Tocolíticos/efeitos adversos
8.
Ultrasound Obstet Gynecol ; 28(7): 911-7, 2006 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-17094077

RESUMO

OBJECTIVES: To identify important factors in the differential diagnosis of renal cysts associated with hyperechogenic kidneys. METHODS: This was a retrospective multicenter study. We identified 93 fetuses presenting between 1990 and 2002 with hyperechogenic kidneys and which had a diagnosis of nephropathy confirmed later. We analyzed retrospectively the prenatal ultrasound findings of those fetuses which were found sonographically to have renal cysts. RESULTS: Of the 93 fetuses presenting with hyperechogenic kidneys and with a later diagnosis of nephropathy, there were 28 with autosomal dominant polycystic kidney disease (ADPKD), 31 with autosomal recessive polycystic kidney disease (ARPKD), 11 with Bardet-Biedl syndrome, nine with Meckel-Gruber syndrome, six with Ivemark II syndrome, one with Jarcho-Levin syndrome, one with Beemer syndrome and one with Meckel-like syndrome. One third of the fetuses (30/93) had renal cysts. Cystic characteristics (size, location, number) were not very useful for diagnosis; more useful was diagnosis of an associated malformation. Three (11%) of the fetuses with ADPKD had cysts, as did nine (29%) of those with ARPKD, three (27%) of those with Bardet-Biedl syndrome, all (100%) of those with Meckel-Gruber syndrome, three (50%) of those with Ivemark II syndrome, and each of the three cases with other syndromes (Jarcho-Levin, Beemer and Meckel-like syndromes). None of the cases with trisomy 13 had cysts. There were no associated malformations in the 12 cases with renal cysts and polycystic kidney disease; the other 18 cases with renal cysts were associated with malformations that were often specific, such as polydactyly in Bardet-Biedl and Beemer syndromes, occipital defect and Dandy-Walker malformation in Meckel-Gruber or Meckel-Gruber-like syndromes, and thoracic and/or vertebral abnormalities in Jarcho-Levin and Beemer syndromes. CONCLUSION: Renal cysts associated with hyperechogenic kidneys are not rare. The clue to diagnosis is the demonstration of an associated malformation. If no malformation is found, the main diagnosis remains polycystic kidney disease, i.e. ARPKD or ADPKD.


Assuntos
Síndrome de Bardet-Biedl/diagnóstico por imagem , Rim/anormalidades , Doenças Renais Policísticas/diagnóstico por imagem , Ultrassonografia Pré-Natal/métodos , Síndrome de Bardet-Biedl/embriologia , Diagnóstico Diferencial , Feminino , Humanos , Recém-Nascido , Rim/diagnóstico por imagem , Masculino , Linhagem , Doenças Renais Policísticas/embriologia , Gravidez , Diagnóstico Pré-Natal , Estudos Retrospectivos
9.
Prenat Diagn ; 26(13): 1254-5, 2006 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-17089441

RESUMO

We suggest the term 'hyper-echogenic colon' to describe a hyperechoic foetal colonic content with no other intestinal abnormality. This is a rare pattern, which to our knowledge, has never been correlated with a specific pathology. The accidental observation of a cystine kidney stone in an infant who presented with this sign during the prenatal period made it possible to diagnose this disease retrospectively in two other children.


Assuntos
Colo/diagnóstico por imagem , Colo/embriologia , Cistinúria/diagnóstico , Ultrassonografia Pré-Natal , Cálculos da Bexiga Urinária/diagnóstico , Adulto , Pré-Escolar , Cistinúria/complicações , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Gravidez , Terceiro Trimestre da Gravidez , Estudos Retrospectivos , Cálculos da Bexiga Urinária/etiologia
10.
Ultrasound Obstet Gynecol ; 27(3): 296-300, 2006 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-16450359

RESUMO

OBJECTIVE: To define a specific sonographic pattern for the appearance of the kidneys in fetuses affected by Meckel-Grüber syndrome (MGS). METHODS: This was a retrospective analysis of 30 cases, collected from five centers, with ultrasound features suggestive of MGS. Only fetuses with a confirmed diagnosis of MGS were finally included. Analysis included a detailed evaluation of the sonographic findings and comparison with pathological follow-up. RESULTS: Seventeen cases met the pathological criteria for a diagnosis of MGS and were included in the study. In all cases, a typical sonographic pattern was seen: the kidneys were enlarged (mean, + 4.8 SD) and showed unusual corticomedullary differentiation, occurring as early as the first trimester. In most cases, the medullary areas appeared excessively large and mottled due to the presence of multiple small cysts. CONCLUSIONS: The kidneys of fetuses with MGS are enlarged, cystic and have unusual corticomedullary differentiation. These features can be observed as early as the first and early second trimesters.


Assuntos
Doenças Fetais/diagnóstico por imagem , Doenças Renais Císticas/diagnóstico por imagem , Sistema Nervoso Central/anormalidades , Encefalocele/diagnóstico por imagem , Encefalocele/patologia , Feminino , Idade Gestacional , Humanos , Doenças Renais Císticas/patologia , Idade Materna , Polidactilia/diagnóstico por imagem , Polidactilia/patologia , Gravidez , Síndrome , Ultrassonografia Pré-Natal
11.
Ultrasound Obstet Gynecol ; 24(1): 55-61, 2004 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-15229917

RESUMO

OBJECTIVE: To determine whether a specific prenatal sonographic pattern can be identified for autosomal dominant polycystic kidney disease (ADPKD) and if so whether it would be helpful in orienting complementary analysis, properly counseling parents and adapting pregnancy management. METHODS: A retrospective multicenter study was conducted in four prenatal diagnostic centers. The records of fetuses with a prenatal ultrasound examination revealing abnormal kidneys and with a final diagnosis of ADPKD were analyzed. Ultrasound analysis included: amount of amniotic fluid, bladder size, renal length, presence or absence of renal cysts and size of renal pelves, and was focused on parenchyma echogenicity and status of corticomedullary differentiation. Postnatal follow-up was reviewed. RESULTS: Of the 27 patients included in the study, 25 had hyperechogenic renal cortex and 20 had hypoechogenic medulla resulting in increased corticomedullary differentiation (CMD). In six cases, the medulla was hyperechogenic leading to absent or decreased CMD. One patient had normal cortical echogenicity and CMD. Renal cysts were present during the prenatal period in four patients (at 22 weeks in one case and after 30 weeks in three cases). In 12 patients, the cysts appeared after birth (within the first 6 months of postnatal life in 10 cases and by the age of 1 year in two cases). Elevated blood pressure was observed in only two cases and moderate chronic renal failure in one case. CONCLUSION: We have described the sonographic presentation in fetuses with ADPKD: moderately enlarged hyperechogenic kidneys with increased CMD. Although not specific to ADPKD, these findings should prompt familial screening. Other prenatal sonographic features (absent or decreased CMD and cortical cysts) are less frequent.


Assuntos
Rim/diagnóstico por imagem , Rim Policístico Autossômico Dominante/diagnóstico por imagem , Ultrassonografia Pré-Natal , Líquido Amniótico , Feminino , Seguimentos , Humanos , Lactente , Recém-Nascido , Rim/embriologia , Rim Policístico Autossômico Dominante/embriologia , Rim Policístico Autossômico Dominante/genética , Gravidez , Estudos Retrospectivos , Bexiga Urinária/diagnóstico por imagem , Bexiga Urinária/embriologia
12.
Prenat Diagn ; 24(3): 198-201, 2004 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-15057953

RESUMO

Amniotic band syndrome or amniotic disruption complex is a well-known congenital limb abnormality, which occurs in 1 in 1200 to 1 in 15,000 live births. In cases of an isolated band constriction, it has been speculated that the bands lead to decreased blood flow in the constricted limb and subsequent natural amputation. Fetal surgery could be considered in these situations in order to release the constriction band in threatened limb amputation. We present a case of a tight constriction ring secondary to amniotic band syndrome with a favourable outcome, despite the failure of an attempted surgical procedure.


Assuntos
Síndrome de Bandas Amnióticas , Fetoscopia , Ultrassonografia Pré-Natal , Adulto , Síndrome de Bandas Amnióticas/diagnóstico por imagem , Síndrome de Bandas Amnióticas/patologia , Síndrome de Bandas Amnióticas/cirurgia , Feminino , Idade Gestacional , Humanos , Recém-Nascido , Doenças do Recém-Nascido , Gravidez , Resultado do Tratamento
13.
Acta Paediatr ; 92(10): 1223-5, 2003 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-14632345

RESUMO

UNLABELLED: Oculoauriculovertebral dysplasia, also called Goldenhar syndrome, includes several anomalies: epibulbar dermoids or lipodermoids, microtia, mandibular hypoplasia, vertebral, skeletal, cardiac and kidney anomalies, among others. Tumours have also been observed in patients with oculoauriculovertebral dysplasia. We report the first case of oculoauriculovertebral dysplasia associated with a neuroblastoma. This tumour consists of cells identical to early migratory neural crest cells in the embryo. Several theories have been proposed regarding the pathogenetic explanation of oculoauriculovertebral dysplasia. Currently, some researchers have suggested a deficiency in mesodermal formation or defective interaction between neural crest and mesoderm as a possible aetiology. CONCLUSION: It is suggested that the case reported here is an additional argument for an anomaly in neural crest cell migration or interaction with the mesoderm in the pathogenesis of oculoauriculovertebral dysplasia.


Assuntos
Neoplasias das Glândulas Suprarrenais/fisiopatologia , Síndrome de Goldenhar/complicações , Neuroblastoma/fisiopatologia , Neoplasias das Glândulas Suprarrenais/complicações , Evolução Fatal , Síndrome de Goldenhar/fisiopatologia , Humanos , Recém-Nascido , Masculino , Neuroblastoma/complicações
14.
J Gynecol Obstet Biol Reprod (Paris) ; 32(8 Pt 1): 693-704, 2003 Dec.
Artigo em Francês | MEDLINE | ID: mdl-15067893

RESUMO

Amniotic band syndrome is a collection of fetal congenital malformations, affecting mainly the limbs, but also the craniofacial area and internal organs. Two mains pathogenic mechanisms are proposed: early amnion rupture (exogenous theory) leading to fibrous bands, which entrap the fetal body; the endogenous theory privileges vascular compromise, mesoblastic strings not being a causal agent. The outcome of the disease depends on the gravity of the malformation. Termination of the pregnancy is usually proposed at the time of the diagnostic of severe craniofacial and visceral abnormalities, whereas minor limb defects can be repaired with postnatal surgery. In case of an isolated amniotic band with a constricted limb, in utero lysis of the band can be considered to avoid a natural amputation. However, as the exact etiology of amniotic band syndrome remains unknown and its natural course unpredictable, prenatal surgery continues to be controversial. Doppler studies of the constricted limb could be of useful predictive value of in utero amputation, and therefore could be helpful to determine when in utero treatment should be considered.


Assuntos
Anormalidades Múltiplas/diagnóstico , Síndrome de Bandas Amnióticas/diagnóstico , Diagnóstico Pré-Natal , Anormalidades Múltiplas/etiologia , Anormalidades Múltiplas/cirurgia , Adulto , Síndrome de Bandas Amnióticas/etiologia , Síndrome de Bandas Amnióticas/cirurgia , Feminino , Doenças Fetais/cirurgia , Ruptura Prematura de Membranas Fetais/complicações , Humanos , Recém-Nascido , Procedimentos Cirúrgicos Minimamente Invasivos , Gravidez , Ultrassonografia Pré-Natal
15.
J Radiol ; 83(6 Pt 1): 731-5, 2002 Jun.
Artigo em Francês | MEDLINE | ID: mdl-12149590

RESUMO

PURPOSE: To analyze the prevalence of genitourinary malformations associated with multicystic dysplastic kidney (MCDK). PATIENTS: and method: A retrospective analysis of medical and imaging records of 54 neonates who had the prenatal diagnosis of MCDK was carried out. All infants had the following examinations during their first month of life: ultrasound, voiding cystourethrography and intravenous urography. Genital and urinary abnormalities were recorded. RESULTS: Vesicoureteric reflux was present ipsilaterally in 17% cases, on the opposite side in 31% cases. Ureteropelvic junction obstruction was found on the opposite side in 7% cases. Four cases of megaureters, one child with ureteric duplication, 3 boys with posterior urethral valves, 1 with reflux into the ejaculatory duct, one case of megacystis with reflux and one child with ureterocele were identified. Genital anomalies were: 2 cases of seminal vesicle cysts, one case of absent testis, 5 children with inguinal hernia, one boy with incomplete foreskin and one with hypospadias. CONCLUSION: Embryology may explain the highest prevalence of genito-urinary abnormalities on both sides in neonates with MCDK. Hence, a prompt clinical and uroradiological evaluation in these patients with a single functional kidney should be performed.


Assuntos
Anormalidades Múltiplas/diagnóstico , Anormalidades Múltiplas/epidemiologia , Rim Displásico Multicístico/diagnóstico , Rim Displásico Multicístico/epidemiologia , Diagnóstico Pré-Natal/métodos , Anormalidades Urogenitais/diagnóstico , Anormalidades Urogenitais/epidemiologia , Anormalidades Múltiplas/embriologia , Centros Médicos Acadêmicos , Feminino , França/epidemiologia , Humanos , Hipospadia/diagnóstico , Hipospadia/epidemiologia , Recém-Nascido , Masculino , Rim Displásico Multicístico/embriologia , Triagem Neonatal/métodos , Prevalência , Estudos Retrospectivos , Testículo/anormalidades , Ureter/anormalidades , Obstrução Ureteral/diagnóstico , Obstrução Ureteral/epidemiologia , Ureterocele/diagnóstico , Ureterocele/epidemiologia , Uretra/anormalidades , Anormalidades Urogenitais/embriologia , Urografia , Refluxo Vesicoureteral/diagnóstico , Refluxo Vesicoureteral/epidemiologia
16.
Gynecol Obstet Fertil ; 30(4): 282-5, 2002 Apr.
Artigo em Francês | MEDLINE | ID: mdl-12043502

RESUMO

OBJECTIVE: Our study was designed to explain determinants of nonprogressive labor in nulliparous patients. STUDY DESIGN: One hundred consecutive nulliparous patients have got a cesarean section for active-phase arrest of labor after two hours of active management. Intrauterine pressure was monitored for all of them and a X-ray pelvimetry was done after surgery. RESULTS: Eighty-three percent of patients showed X-ray data considered as normal; hypotonic labor was found in 50% of cases and occiput posterior position in 60%. CONCLUSIONS: Our results suggest that occiput position and functional dystocia are more common in case of nonprogressive labor than abnormal measurements of the obstetrical pelvis.


Assuntos
Distocia/complicações , Complicações do Trabalho de Parto/etiologia , Feminino , Humanos , Apresentação no Trabalho de Parto , Primeira Fase do Trabalho de Parto , Segunda Fase do Trabalho de Parto , Paridade , Pelve/anormalidades , Pelve/anatomia & histologia , Gravidez , Resultado da Gravidez
17.
AJNR Am J Neuroradiol ; 22(4): 767-72, 2001 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11290497

RESUMO

BACKGROUND AND PURPOSE: Pericallosal lipomas are rare tumors. Few reports have included their imaging characteristics. Furthermore, little is known about their evolutive course. Our purpose was to describe the imaging features of seven cases of pericallosal lipoma diagnosed in utero and followed up after birth. METHODS: We reviewed seven cases of pericallosal lipoma diagnosed by obstetric sonography (n = 7) and examined by fetal MR imaging (n = 5). Analysis of the complementary findings provided by fetal MR imaging was conducted. All findings were correlated with the postnatal imaging and clinical findings. RESULTS: Obstetric sonography easily showed the pericallosal lipoma in all seven patients. In one, however, it was misinterpreted as intracranial hemorrhage. The morphology and integrity of the underlying corpus callosum were less easy to assess by using sonography. Fetal MR imaging confirmed the fatty content and location of the lesion in all five cases. It showed the choroidal extension in two patients and the type of associated callosal anomaly in another patient better than did sonography. In two patients, the lipoma grew, as revealed by subsequent postnatal MR imaging. The results of the neurologic examinations remained normal for the five surviving patients at a mean follow-up of 3 years (1 month-9 years). CONCLUSION: Obstetric sonography is able to easily show pericallosal lipoma. Fetal MR imaging may be useful to characterize the lipomatous nature and the extension of the lipoma and the status of the corpus callosum. Long-term follow-up is necessary to understand the clinical consequences of such lesions.


Assuntos
Agenesia do Corpo Caloso , Neoplasias Encefálicas/congênito , Lipoma/congênito , Imageamento por Ressonância Magnética , Diagnóstico Pré-Natal , Ultrassonografia Pré-Natal , Neoplasias Encefálicas/diagnóstico , Pré-Escolar , Corpo Caloso/patologia , Progressão da Doença , Feminino , Seguimentos , Humanos , Lactente , Recém-Nascido , Lipoma/diagnóstico , Masculino , Exame Neurológico , Gravidez
18.
Radiology ; 219(1): 236-41, 2001 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11274563

RESUMO

PURPOSE: To plot normal fetal lung volume (FLV) obtained with fast spin-echo magnetic resonance (MR) images against gestational age; to investigate the correlation between lung growth and fetal presentation, sex, and ultrasonographic (US) biometric measurements; and to investigate its potential application in fetuses with thoracoabdominal malformations. MATERIALS AND METHODS: In a prospective multicenter study, 336 fetuses suspected of having central nervous system disorders underwent fast spin-echo T2-weighted lung MR imaging. Data obtained at 21-38 weeks gestation in 215 fetuses without thoracoabdominal malformations and with normal US biometric findings were selected for an FLV normative curve. FLV measurements obtained at pathologic examination with an immersion method were compared with MR FLV measurements in 11 fetuses. MR FLV values in 16 fetuses with thoracoabdominal malformations were compared with the normative curve. RESULTS: Normal FLV increased with gestational age as a power curve; the spread of values increased with age. Interobserver correlation was excellent (R(2) = 0.96). FLV measurements at MR imaging were 0.90 times those at pathologic examination. A constant ratio (0.78) between FLV on the left and right sides was observed. No significant difference in FLV was observed between fetal presentations. Normal FLV was observed in all fetuses with cystic adenomatoid malformations and in four of six with oligohydramnios. Lowest FLV values were observed in fetuses with diaphragmatic hernia. CONCLUSION: In fetuses with normal lungs, FLV distribution against gestational age is easily assessed in utero with fast spin-echo T2-weighted MR imaging. These preliminary findings illustrate the potential for comparing FLV measurements in fetuses at risk of lung hypoplasia with normative values.


Assuntos
Maturidade dos Órgãos Fetais/fisiologia , Pulmão/embriologia , Imageamento por Ressonância Magnética , Diagnóstico Pré-Natal , Anormalidades Múltiplas/diagnóstico , Feminino , Idade Gestacional , Humanos , Recém-Nascido , Pulmão/patologia , Masculino , Gravidez , Estudos Prospectivos , Valores de Referência
20.
J Radiol ; 79(2): 133-7, 1998 Feb.
Artigo em Francês | MEDLINE | ID: mdl-9757230

RESUMO

In spite of its invasiveness, voiding cystourethrography remains the gold-standard examination for detecting vesico-ureteric reflux. The aim of this study was to determine if voiding cysto-urethrography is useful at any pediatric age in girls after a first acute pyelonephritis. 152 patients have been retrospectively studied. Both reflux frequency and grade progressively decreased according to age. Sonography was unable to predict reflux. In more than 3-year-old girls, 8/30 children with reflux had voiding dysfunction. We suggest clinical and/or a flow-metric evaluation for voiding dysfunction prior to voiding cystourethrography. After 9 years, reflux was so rare that voiding cystourethrography should be discussed on an individual basis.


Assuntos
Pielonefrite/diagnóstico por imagem , Urografia , Refluxo Vesicoureteral/diagnóstico por imagem , Doença Aguda , Adolescente , Criança , Pré-Escolar , Feminino , Seguimentos , Humanos , Lactente , Sensibilidade e Especificidade , Bexiga Urinária/diagnóstico por imagem
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA