1.
Cell Host Microbe
; 32(3): 298-300, 2024 Mar 13.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38484708
RESUMO
Pyridoxine-unresponsive homocystinuria has lifelong implications for health. In this issue, Perreault and colleagues present evidence that orally delivered engineered probiotic Escherichia Coli Nissle SYNB1353 is a promising candidate in reducing homocysteine, with successful trials in mice, monkeys, and humans. However, further probiotic optimization and safety assessments are required.