1.
Bioorg Med Chem Lett
; 8(19): 2653-6, 1998 Oct 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-9873597
RESUMO
A novel series of pentafluorobenzenesulfonamides has been shown to inhibit the growth of a variety of human tumor cell lines. Among the cell types against which these agents were evaluated were the multidrug resistant (MDR) cell lines MCF-7/ADR and P388/ADR. The cytotoxic activity of members of this series of compounds was not affected by the multidrug resistant pump in MCF-7/ADR or P388/ADR cells.
Assuntos
Antineoplásicos/farmacologia , Resistência a Múltiplos Medicamentos , Sulfonamidas/farmacologia , Resistencia a Medicamentos Antineoplásicos , Ensaios de Seleção de Medicamentos Antitumorais , Fluorbenzenos/farmacologia , Humanos , Fenótipo , Células Tumorais Cultivadas
2.
Chem Res Toxicol
; 2(4): 227-9, 1989.
Artigo
em Inglês
| MEDLINE
| ID: mdl-2519778