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1.
Med Parazitol (Mosk) ; (1): 9-13, 2014.
Artigo em Russo | MEDLINE | ID: mdl-24738219

RESUMO

The authors have attempted to systematize the currently known specific morphological features of the composition of Blastocystis spp. existing in different forms and to present this material as a reference table, by understanding the need for further data clarification. In addition, the paper describes observations of variations in the forms of human blastocysts. In particular, it depicts the species of multinucleated cysts, the identification of which may cause difficulties in diagnosing and differentiating these forms with some representative species of the genus Entamoeba.


Assuntos
Infecções por Blastocystis/diagnóstico , Blastocystis/ultraestrutura , Núcleo Celular/ultraestrutura , Estágios do Ciclo de Vida/fisiologia , Animais , Blastocystis/classificação , Blastocystis/crescimento & desenvolvimento , Infecções por Blastocystis/parasitologia , Citoplasma/ultraestrutura , Fezes/parasitologia , Humanos , Microscopia Eletrônica , Mitocôndrias/ultraestrutura
2.
Med Parazitol (Mosk) ; (1): 44-8, 2004.
Artigo em Russo | MEDLINE | ID: mdl-15042749

RESUMO

Trials of trichlorophen have shown its high efficacy on models of cestode infections: hymenolepiasis (at the adult and cysticercoid stages of development on three types of animals: outbred albino mice, albino rats and golden hamsters), preimaginal echinococciasis alveolaris, larval alveolar echinococciasis (at the early stage of development of the parasite in experiments on cotton rats). The high nematodical activity of trichlorophen was first found on models of trichocephaliasis in DBA/2y mice, nippostrongyloidiasis (in in vitro experiments), and aspiculuriasis in outbred mice. The agent proved to be ineffective at the tissue developmental stage of Hymenolepsis nana (H. nana), the dwarf tapeworm, in albino mice, during experimental opisthorchiasis in golden hamsters. It showed a low efficacy in treating trichinosis in outbred albino mice. Unlike carbamatebenzimidazoles, trichlorophen was inactive at the tissue stage of H. nana; it exerted no effects on the eggs of a dwarf tapeworm in trichinosis. Trichlorophen was also inactive in treating experimental opisthorchiasis in golden hamsters.


Assuntos
Anti-Helmínticos/uso terapêutico , Clorofenóis/uso terapêutico , Helmintíase/tratamento farmacológico , Administração Oral , Animais , Anti-Helmínticos/administração & dosagem , Infecções por Cestoides/tratamento farmacológico , Clorofenóis/administração & dosagem , Cricetinae , Relação Dose-Resposta a Droga , Avaliação Pré-Clínica de Medicamentos , Helmintíase/parasitologia , Hymenolepis/efeitos dos fármacos , Hymenolepis/fisiologia , Camundongos , Camundongos Endogâmicos DBA , Infecções por Nematoides/tratamento farmacológico , Nippostrongylus/efeitos dos fármacos , Nippostrongylus/fisiologia , Ratos , Federação Russa
3.
Med Parazitol (Mosk) ; (1): 48-50, 2004.
Artigo em Russo | MEDLINE | ID: mdl-15042750

RESUMO

Experiments have established the high efficacy of combinations of the micronized dosage form of trichlorophen, with albendazole or medamine in treating trichocephaliasis (its causative agent being Trichocephalus muris) in DBA/2st mice and that of trichlorophen in combination with azinox or fenasal in outbred albino mice with hymenolepiasis (its causative agent being Hymenolepis nana). These combinations are promising in treating patients with cestodosis and nemadosis, respectively.


Assuntos
Anti-Helmínticos/uso terapêutico , Carbamatos , Clorofenóis/uso terapêutico , Helmintíase/tratamento farmacológico , Praziquantel/análogos & derivados , Administração Oral , Albendazol/uso terapêutico , Animais , Anti-Helmínticos/administração & dosagem , Benzimidazóis/uso terapêutico , Clorofenóis/administração & dosagem , Avaliação Pré-Clínica de Medicamentos , Quimioterapia Combinada , Himenolepíase/tratamento farmacológico , Camundongos , Camundongos Endogâmicos DBA , Niclosamida/uso terapêutico , Praziquantel/uso terapêutico , Tricuríase/tratamento farmacológico
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