RESUMO
Fungal septicaemia is a serious and potentially fatal condition. We report 4 cases in patients with Cystic Fibrosis (CF) associated with totally implantable venous access device system (TIVADS).
Assuntos
Candidíase/etiologia , Cateterismo Periférico/efeitos adversos , Cateteres de Demora/efeitos adversos , Fibrose Cística/complicações , Fungemia/etiologia , Próteses e Implantes/efeitos adversos , Infecções Relacionadas à Prótese/etiologia , Adulto , Candidíase/tratamento farmacológico , Pré-Escolar , Fibrose Cística/terapia , Feminino , Fungemia/tratamento farmacológico , Humanos , MasculinoRESUMO
We report a rare case of Wegener's granulomatosis involving the prostate in a 28-year-old man. The initial medical treatment was effective, but surgical intervention was required to manage late complications.
Assuntos
Granulomatose com Poliangiite/complicações , Doenças Prostáticas/etiologia , Adulto , Humanos , Masculino , Doenças Prostáticas/cirurgiaRESUMO
This report describes two cases of segmental pulmonary vein occlusion secondary to lung malignancy in which lung biopsies showed histological features of veno-occlusive disease. These are the first cases to be reported in the literature in which such lung parenchymal histological changes are described in association with lung malignancy.
Assuntos
Carcinoma de Células Escamosas/complicações , Leiomiossarcoma/complicações , Neoplasias Pulmonares/complicações , Pneumopatia Veno-Oclusiva/etiologia , Adulto , Carcinoma de Células Escamosas/patologia , Evolução Fatal , Feminino , Humanos , Leiomiossarcoma/patologia , Neoplasias Pulmonares/patologia , Pessoa de Meia-Idade , Veias Pulmonares/patologia , Pneumopatia Veno-Oclusiva/patologia , Tomografia Computadorizada por Raios X/métodosRESUMO
The combination of cytological and histological techniques has significantly increased the accuracy of fibreoptic bronchoscopy (FOB) in the diagnosis of lung cancer. We tested the hypothesis that cytological examination of material obtained from the whole endobronchial brush might increase the diagnostic yield in patients where conventional brush specimens were negative. Fifty patients who had undergone FOB for suspected lung cancer were studied prospectively. Bronchial lavage, bronchial biopsy and conventional brushing were performed. The whole endobronchial brush was then cut off the end of its wire and transported in a universal pot containing Shandon cytospin collection fluid. The material was dislodged from the whole brush using a vortex and the remaining fluid was centrifuged at 2,000 r.p.m. The fluid concentrate was used to maketwo cytopsin preparations. Papanicolaou stain was used. Fifty patients were studied, of which thirty-nine (78%) had endoscopicaly visible tumour. Of those, bronchial biopsy conventional brushing lavage and whole brush were positive for malignant cells in 31 (79.4%), 29 (74.3%), 21 (53.8%), and 16 (41%) of cases, respectively. A diagnosis of lung cancer was confirmed in 35 (89.7%) cases of endoscopicaly visible tumour. Conventional brushing was positive in two out of 11 (18.2%) cases with no visible tumour. Whole brush analysis was not positive in any of the cases with negative conventional brushings and was the least sensitive test in detecting malignancy Whole endobronchial brush analysis has no advantage in bronchoscopic diagnosis of patients with suspected lung cancer.