Evaluation of the Effectiveness of Geogrids Manufactured from Recycled Plastics for Slope Stabilization-A Case Study.

This study aimed to investigate the sustainable use of recycled plastics, specifically polypropylene (PP) and high-density polyethylene (HDPE), in the manufacture of geogrids for geotechnical and civil engineering applications. Plastics were collected from a recycling center, specifically targeting containers used for food, cleaning products, and other domestic packaging items. These plastics were sorted according to the Möbius triangle classification system, with HDPE (#2) and PP (#5) being the primary categories of interest. The research methodologically evaluates the mechanical properties of PP/HDPE (0/100, 25/75, 50/50, 75/25 and 100/0% w/w) composites through tensile and flexural tests, exploring various compositions and configurations of geogrids. The results highlight the superiority of pure recycled HDPE processed into 1.3 mm thick laminated yarns and hot air welded for 20 to 30 s, exhibiting a deformation exceeding 60% in comparison to the PP/HDPE composites. Through SolidWorks® Simulation, it was shown that the adoption of a trigonal geogrid geometry optimizes force distribution and tensile strength, significantly improving slope stabilization efficiency. Based on the results obtained, a laboratory-scale prototype geogrid was developed using an extrusion process. The results underscore the importance of careful composite design and yarn configuration selection to achieve the desired mechanical properties and performance in geogrid applications. It emphasizes the potential of recycled plastics as a viable and environmentally friendly solution for stabilizing slopes, contributing to the reduction in plastic waste and promoting sustainable construction practices.

A genetic profiling guideline to support diagnosis and clinical management of lymphomas.

The new lymphoma classifications (International Consensus Classification of Mature Lymphoid Neoplasms, and 5th World Health Organization Classification of Lymphoid Neoplasms) include genetics as an integral part of lymphoma diagnosis, allowing better lymphoma subclassification, patient risk stratification, and prediction of treatment response. Lymphomas are characterized by very few recurrent and disease-specific mutations, and most entities have a heterogenous genetic landscape with a long tail of recurrently mutated genes. Most of these occur at low frequencies, reflecting the clinical heterogeneity of lymphomas. Multiple studies have identified genetic markers that improve diagnostics and prognostication, and next-generation sequencing is becoming an essential tool in the clinical laboratory. This review provides a "next-generation sequencing" guide for lymphomas. It discusses the genetic alterations of the most frequent mature lymphoma entities with diagnostic, prognostic, and predictive potential and proposes targeted sequencing panels to detect mutations and copy-number alterations for B- and NK/T-cell lymphomas.

Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma.

The mechanisms triggering metastasis in pheochromocytoma/paraganglioma are unknown, hindering therapeutic options for patients with metastatic tumors (mPPGL). Herein we show by genomic profiling of a large cohort of mPPGLs that high mutational load, microsatellite instability and somatic copy-number alteration burden are associated with ATRX/TERT alterations and are suitable prognostic markers. Transcriptomic analysis defines the signaling networks involved in the acquisition of metastatic competence and establishes a gene signature related to mPPGLs, highlighting CDK1 as an additional mPPGL marker. Immunogenomics accompanied by immunohistochemistry identifies a heterogeneous ecosystem at the tumor microenvironment level, linked to the genomic subtype and tumor behavior. Specifically, we define a general immunosuppressive microenvironment in mPPGLs, the exception being PD-L1 expressing MAML3-related tumors. Our study reveals canonical markers for risk of metastasis, and suggests the usefulness of including immune parameters in clinical management for PPGL prognostication and identification of patients who might benefit from immunotherapy.

Lesiones y muertes no intencionales en el departamento de Antioquia, Colombia. Estudio observacional descriptivo, 2016 y 2017 / Unintentional injuries and deaths in the department of Antioquia, Colombia. An observational descriptive study, 2016 - 2017

Introducción: la Organización Mundial de la Salud considera a las lesiones accidentales o lesiones no intencionales (LNI) como un problema de salud pública por su efecto sobre la discapacidad y mortalidad en la población general. Objetivo: presentar y analizar los datos de LNI y muertes accidentales registrados por el Instituto Nacional de Medicina Legal y Ciencias Forenses en el departamento de Antioquia, durante los años 2016 y 2017. Métodos: estudio descriptivo basado en la información recolectada por el Instituto Nacional de Medicina Legal y Ciencias Forenses. Se calcula ron las tasas de lesionados y muertes por 100.000 habitantes/año y el análisis estadístico se realizó con el paquete estadístico SPSS® versión 24.0. Resultados: durante 2016 y 2017 se registró una tasa de morbilidad de LNI de 7,86 y 7,21 casos por 100.000 habitantes, respectivamente, similar a la del promedio nacional. Fue mayor el número de casos en hombres que en mujeres, principalmente entre los 18 y los 34 años. La tasa de mortalidad reportada fue de 10,10 y 11,05 por cada 100.000 habitantes para el mismo periodo. Las LNI fueron más frecuentes en personas con bajo nivel educativo, del área urbana, y el mecanismo traumático más frecuente fue el contundente. Conclusiones: este estudio evidencia disminución en las tasas de LNI y aumento de la mortalidad accidental en Antioquia, comparada con años anteriores. Dicho comportamiento es diferente a lo reportado por la literatura internacional. Se requieren investigaciones que analicen otras fuentes generadoras de información acerca de las LNI, con la finalidad de estimar con mayor precisión la ocurrencia del fenómeno y sus variables asociadas.

Background: The World Health Organization con siders unintentional injuries (UI) as an international public health problem, due to their effect on disability and mortality in the general population. Objective: To present and analyze the data on UI and accidental death collected by the National Institute of Legal Medicine and Forensic Sciences in the Department of Antioquia, Colombia, between 2016 and 2017. Methods: Descriptive study based on the information collected by the National Institute of Legal Medicine and Forensic Sciences. The rates of injuries and deaths per 100,000 inhabitants / year were calculated, and the statistical analysis was made using SPSS® version 24.0. Results: In the years 2016 and 2017, there was a morbidity rate of UI of 7.86 and 7.21 cases per 100,000 inhabitants, respectively, similar to the national average. The number of cases was greater in men than in women, mainly between 18 and 34 years of age. The reported accidental mortality rate was 10.10 and 11.05 per 100,000 inhabitants for the years 2016 and 2017, respectively. The UI were more frequent in people with low educational level, from the urban area, and the most frequent traumatic mechanism was the blunt one. Conclusions: This study shows a reduction in the rates of UI and an increase of the rates of accidental death in Antioquia compared to the previous years. This trend is different to the previously reported on international literature. More studies analyzing other sources of information on variables like UI are needed in this field, in order to precisely estimate the occurrence of this event and its associated variables.

Worse outcome and distinct mutational pattern in follicular lymphoma with anti-HBc positivity.

Epidemiological studies have demonstrated the association between hepatitis B virus (HBV) infection and B-cell non-Hodgkin lymphoma (NHL), mainly for diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL). We studied a cohort of 121 patients with FL for HBV infection status, clinical features, and gene mutational profile. Anti-HBc was detectable in 16 patients (13.2%), although all had undetectable HBV DNA. Anti-HBcore+ (anti-HBc+) cases presented with older age at diagnosis than anti-HBc- cases (68.1 vs 57.2 years; P = .007) and higher ß2-microglobulin (56.3% vs 28.9%; P = .04). All patients included in the study fulfilled criteria for treatment and received therapy with rituximab or rituximab-containing chemotherapy. There were no episodes of HBV reactivation or HBV hepatitis during treatment and/or maintenance. Remarkably, anti-HBc+ patients had significantly lower 10-year progression-free survival (PFS; 12.9% vs 58.3%; P < .0001) and overall survival (OS; 22.0% vs 86.2%; P < .0001), that remained at multivariate analysis. Gene mutational profiling of all cases showed that anti-HBc+ cases had higher incidence of ARID1A mutations and absence of EP300 mutations, 2 key epigenetic regulators in FL. Overall, our study shows that FL patients with resolved HBV infection have a worse outcome independently of other well-known clinical risk factors and a distinct gene mutational profile.

Genetic and phenotypic attributes of splenic marginal zone lymphoma.

Splenic marginal zone B-cell lymphoma (SMZL) is a heterogeneous clinico-biological entity. The clinical course is variable, multiple genes are mutated with no unifying mechanism, and essential regulatory pathways and surrounding microenvironments are diverse. We sought to clarify the heterogeneity of SMZL by resolving different subgroups and their underlying genomic abnormalities, pathway signatures, and microenvironment compositions to uncover biomarkers and therapeutic vulnerabilities. We studied 303 SMZL spleen samples collected through the IELSG46 multicenter international study (NCT02945319) by using a multiplatform approach. We carried out genetic and phenotypic analyses, defined self-organized signatures, validated the findings in independent primary tumor metadata and in genetically modified mouse models, and determined correlations with outcome data. We identified 2 prominent genetic clusters in SMZL, termed NNK (58% of cases, harboring NF-κB, NOTCH, and KLF2 modules) and DMT (32% of cases, with DNA-damage response, MAPK, and TLR modules). Genetic aberrations in multiple genes as well as cytogenetic and immunogenetic features distinguished NNK- from DMT-SMZLs. These genetic clusters not only have distinct underpinning biology, as judged by differences in gene-expression signatures, but also different outcomes, with inferior survival in NNK-SMZLs. Digital cytometry and in situ profiling segregated 2 basic types of SMZL immune microenvironments termed immune-suppressive SMZL (50% of cases, associated with inflammatory cells and immune checkpoint activation) and immune-silent SMZL (50% of cases, associated with an immune-excluded phenotype) with distinct mutational and clinical connotations. In summary, we propose a nosology of SMZL that can implement its classification and also aid in the development of rationally targeted treatments.

High-mobility group box (TOX) antibody a useful tool for the identification of B and T cell subpopulations.

Thymocyte selection-associated high-mobility group box (TOX) is a DNA-binding factor that is able to regulate transcription by modifying local chromatin structure and modulating the formation of multi-protein complexes. TOX has multiple roles in the development of the adaptive immune system including development of CD4 T cells, NK cells and lymph node organogenesis. However very few antibodies recognizing this molecule have been reported and no extensive study of the expression of TOX in reactive and neoplastic lymphoid tissue has been performed to date. In the present study, we have investigated TOX expression in normal and neoplastic lymphoid tissues using a novel rat monoclonal antibody that recognizes its target molecule in paraffin-embedded tissue sections. A large series of normal tissues and B- and T-cell lymphomas was studied, using whole sections and tissue microarrays. We found that the majority of precursor B/T lymphoblastic, follicular and diffuse large B-cell lymphomas, nodular lymphocyte-predominant Hodgkin lymphomas and angioimmunoblastic T-cell lymphomas strongly expressed the TOX protein. Burkitt and mantle cell lymphomas showed TOX expression in a small percentage of cases. TOX was not found in the majority of chronic lymphocytic leukemia, myelomas, marginal zone lymphomas and classical Hodgkin lymphomas. In conclusion, we describe for the first time the expression of TOX in normal and neoplastic lymphoid tissues. The co-expression of TOX and PD-1 identified in normal and neoplastic T cells is consistent with recent studies identifying TOX as a critical regulator of T-cell exhaustion and a potential immunotherapy target. Its differential expression may be of diagnostic relevance in the differential diagnosis of follicular lymphoma, the identification of the phenotype of diffuse large B-cell lymphoma and the recognition of peripheral T-cell lymphoma with a follicular helper T phenotype.

Evaluation of the MD Anderson tumor score for diffuse large B-cell lymphoma in the rituximab era.

OBJECTIVES: Diffuse large B-cell lymphoma (DLBCL) is an aggressive heterogeneous lymphoma with standard treatment. However, 30%-40% of patients still fail, so we should know which patients are candidates for alternative therapies. IPI is the main prognostic score but, in the rituximab era, it cannot identify a very high-risk (HR) subset. The MD Anderson Cancer Center reported a score in the prerituximab era exclusively considering tumor-related variables: Tumor Score (TS). We aim to validate TS in the rituximab era and to analyze its current potential role. METHODS: From GELTAMO DLBCL registry, we selected those patients homogeneously treated with R-CHOP (n = 1327). RESULTS: Five-years PFS and OS were 62% and 74%. All variables retained an independent prognostic role in the revised TS (R-TS), identifying four different risk groups, with 5-years PFS of 86%, 71%, 50%, and very HR (28%). With a further categorization of three variables of the original TS (Ann Arbor Stage, LDH and B2M), we generated a new index that allowed an improvement in HR assessment. CONCLUSIONS: (a) All variables of the original TS retain an independent prognostic role, and R-TS remains predictive in the rituximab era; (b) R-TS and additional categorization of LDH, B2M, and AA stage (enhanced TS) increased the ability to identify HR subsets.

Incidence of sternalis muscle in the Caldas population (Colombia): anatomical variations / Incidencia del músculo esternal en la población de Caldas (Colombia): variaciones anatómicas

The musculus sternalis is an anatomical variant that occurs in 3-8 % of the world population and its incidence is higher in women. It can be found unilaterally or bilaterally and is located in the anterior wall of the thorax, where its fibers run parallel to the sternum and superficial to the medial part of the pectoralis major muscle. The main objective of this study was to quantify the incidence of musculus sternalis in the population of Caldas (Colombia) and, therefore, 68 cadavers of adult individuals were used during a period of twenty years to determine the incidence of this muscle and describe its anatomical characteristics. Two cadavers had this muscle, which was equivalent to 2.94 % of the sample, where one was located unilaterally and in other bilaterally. In the case of unilateral presence, the muscle presented an oblique direction thatdoes not coincide with any subtype of the classification given for these muscles. In bilateral presentation, both muscles were continuous at their upper ends with the respective sternocleidomastoid muscle. In addition, the right musculus sternalis had a digastric shape, which also does not coincide with any subtype of the classification.

El músculo esternal es una variante anatómica que se presenta entre el 3 % y 8 % de la población mundial y su incidencia es mayor en mujeres. Puede hallarse de manera unilateral o bilateral y se localiza en la pared anterior del tórax, donde sus fibras corren paralelas al esternón y superficial a la región medial del músculo pectoral mayor. El objetivo del presente estudio fue cuantificar la incidencia del músculo esternal en la población de Caldas (Colombia). Fueron revisados 68 cadáveres de individuos adultos durante un lapso de doce años, con el fin de determinar el grado de presencialidad del músculo y sus características anatómicas. Dos cadáveres, que equivale al 2,94 % de la muestra, presentaron el músculo esternal, uno de manera unilateral y el otro bilateral, a los cuales se les hizo una descripción anatómica detallada. En la presentación unilateral, el músculo presentó una dirección oblicua que no coincide con ningún subtipo de la clasificación dada para estos músculos. En la presentación bilateral, ambos músculos se continúan por su extremo superior con el respectivo músculo esternocleidomastoideo. Además, el músculo esternal derecho tiene una configuración digástrica, que tampoco coincide con ningún subtipo de la clasificación.

Inconsistencias de la terminologia anatomica: la vértebra cervical 1 nombrada con el epónimo atlas / Inconsistencies of the terminologia anatomica: first cervical vertebra named with the eponim atlas

La primera vértebra cervical establece una articulación sinovial con los cóndilos del occipital, sin que haya de por medio disco fibrocartilaginoso. Esta articulación es importante para la anatomía funcional del cuello porque, además de soportar el peso de la cabeza en los humanos, permite movimientos de flexión, extensión e inclinación lateral. La primera vértebra es conocida en la Terminologia Anatomica y en la Nomina Anatomica Veterinaria con el nombre de Atlas [C1]. El nombre de Atlas, asignado a la primera vértebra cervical, fue tomado de uno de los titanes de la mitología griega condenado por el dios Zeus a soportar el cielo con sus manos, cabeza y hombros, y que en términos figurativos es la que sostiene el mundo craneal. Sorprende que en el libro oficial de la Terminologia Anatomica y en el de la Nomina Anatomica Veterinaria se mantenga este epónimo por una simple tradición, constituyéndose en una vergonzosa contradicción que debe ser corregida y eliminada.

The first cervical vertebra establishes a synovial joint with the occipital condyles, without having a fibrocartilaginous disc. This joint articulation is important for the functional anatomy of the neck, because in addition to supporting the weight of the head in humans, it allows movements of flexion, extension and lateral inclination. The first cervical vertebra is known in the Terminologia Anatomica and the Nomina Anatomica Veterinaria with the name of Atlas [C1]. The name Atlas, assigned to the first cervical vertebra, was taken from one of the titans of Greek mythology condemned by the god Zeus to support the world with the hands, head, and shoulders, so in figurative terms said vertebra is the one that sustains the cranial world. It is surprising that in the official book of the Terminolgia Anatomica and in the Nomina Anatomica Veterinaria this eponymous is maintained by a simple tradition, constituting a shameful contradiction that must be corrected and eliminated.

Anatomical variations of the caudomedial antebrachial muscles in the crab-eating fox (Cerdocyon thous) / Variaciones anatómicas de los músculos caudo-mediales del antebrazo del zorro perruno (Cerdocyon thous)

The crab-eating fox (Cerdocyon thous) is a wild canid distributed in South America, which is susceptible to traumas caused by captors, accidents on roads, and traps. Due to these events their thoracic limbs can be involved at the level of the forearm, therefore, knowledge of the gross anatomy of its muscles is important in order to develop clinical and surgical procedures at this level compared with the domestic dog. The main objective of this investigation was report the intra and interspecific anatomical variations of the caudomedial forearm muscles in Cerdocyon thous in comparison mainly with the domestic dog. Six dead specimens from wildlife care centres of CORPOCALDAS were used. These were fixed with a solution of formaldehyde, mineral oil and phenic acid. Both thoracic limbs of each specimen were dissected from superficial to deep, emphasizing the caudomedial part of the forearm in order to review the anatomical characteristics of each muscle. These muscles were similar to those reported in the domestic dog, but some variations were observed such as the innervation of the pronator teres muscle by the musculocutaneous nerve in a specimen unilaterally; the formation of an accessory muscle from the ulnar head of the flexor carpi ulnaris muscle in most specimens; and the vestigial presence of the anconeus epitrochlearis muscle in a specimen bilaterally.

El zorro perruno (Cerdocyon thous) es un cánido silvestre distribuido en Sudamérica, el cual es susceptible a traumas causados por captores, accidentes en carreteras y trampas, donde pueden verse involucrados sus miembros torácicos a nivel del antebrazo, por lo tanto, conocer la anatomía de sus músculos es importante, ya que ésta servirá como base en la realización de procedimientos clínicos y quirúrgicos a este nivel en comparación con el perro doméstico. El objetivo principal de esta investigación fue reportar las variaciones anatómicas intra e interespecíficas de los músculos caudo-mediales del antebrazo de C. thous en comparación principalmente con el perro doméstico. Se utilizaron seis especímenes muertos bajo la jurisdicción de CORPOCALDAS. Estos se fijaron con una solución en mezcla de formaldehído, aceite mineral y ácido fénico. Se diseccionaron de superficial a profundo los dos miembros torácicos de cada espécimen, haciendo énfasis en la parte caudo-medial del antebrazo para revisar las características anatómicas de cada músculo, las cuales fueron similares a las reportadas al perro doméstico, pero se observó en un espécimen de manera unilateral la inervación al músculo pronador teres por parte del nervio musculocutáneo; en la mayoría de especímenes se observó la formación de un músculo accesorio a partir de la cabeza ulnar del músculo flexor ulnar del carpo; y en un espécimen la presencia vestigial del músculo ancóneoepitroclear.

Gross anatomy of the intrinsic muscles of the scapular and humeral joint regions in crab-eating fox (Cerdocyon thous, Linnaeus 1776) / Anatomia macroscópica dos músculos intrínsecos das regiões escapular e da articulação do úmero de cachorro-do-mato (Cerdocyon thous, Linnaeus 1776)

The crab-eating fox (Cerdocyon thous) is a wild canid with a wide distribution in South America that is susceptible to traumas due to road kills - an event in which some specimens can survive. Therefore, anatomical studies in their thoracic limbs may be a base for rehabilitation. Six dead specimens were donated by Wildlife Rescue Centre of CORPOCALDAS (Environmental Authority of the Department of Caldas in Colombia), which were then filled with silicone rubber via the common carotid artery, and later fixed with formaldehyde through the external jugular vein. One male was dissected in fresh, and after a week, the others were dissected on the scapular and humeral joint regions. The intrinsic muscles of these regions in the crab-eating fox were homologous to domestic dog, with similar characteristics in terms of shape, origin, insertion, innervation and arterial blood supply. However, the crab-eating fox did have some differences, such as its supraspinatus muscle being conformed by two bellies and attached into the articular capsule of the humeral joint in same manner as the subscapularis muscle, thus conferring greater stability to the humeral. However, the clinical and surgical approaches that must be performed in this region may be homologous to the domestic dog.

Cachorro-do-mato (Cerdocyon thous) é um canideo selvagem amplamente distribuído na América do Sul, susceptível a traumatismos por atropelamentos em rodovias, eventos nos quais alguns animais podem sobreviver. Portanto, estudos anatômicos em seus membros torácicos podem servir como base para sua reabilitação. Seis espécimes mortos foram doados pelo Centro de Resgate de Vida Selvagem da Corporación Autónoma Regional para el Desarrollo de Caldas - CORPOCALDAS, os quais foram preenchidos com borracha de silicone pela artéria carótida comum, e depois fixados com formaldeído através da veia jugular externa. Um macho foi dissecado a fresco e após uma semana, os outros foram dissecados nas regiões da articulação escapular e umeral. Os músculos intrínsecos dessa região no cachorro-do-mato eram homólogos às dos cães domésticos, com características semelhantes na forma, origem, inserção, inervação e suprimento de sangue arterial. No entanto, o cachorro-do-mato apresenta algumas diferenças, como músculo supraespinhal conformado por duas cabeças e unidos na cápsula articular da articulação umeral, da mesma forma que o músculo subescapular, características essas que devem conferir maior estabilidade à articulação do úmero. Apesar disso, as abordagens clínicas e cirúrgicas realizadas nesta região podem ser homólogas ao cão doméstico.

Reflexión sobre los procesos de enseñanza-aprendizaje de la anatomía veterinaria / Reflection on the process of learning-teaching of veterinary anatomy

La anatomía macroscópica veterinaria es una rama de la morfología encargada del estudio de las características normales del cuerpo del animal, y para los procesos de enseñanza-aprendizaje se han utilizado diversos recursos, desde una enseñanza tradicional con cadáveres fijados en formol hasta una complementación con materiales multimedia, exigida por la continua disminución de las horas presenciales en los currículos de medicina veterinaria, por lo tanto, en el presente artículo se muestran diversas metodologías utilizadas tanto en anatomía veterinaria como humana por diversos autores, demostrándonos que cada una tiene ventajas y desventajas pero su integración mejora la comprensión por parte del estudiante, y como autores defendemos esta integración sin alejarnos de la utilización directa del cadáver junto con la aplicación de la terminología anatómica veterinaria actual como principal recurso didáctico en el proceso de enseñanza y aprendizaje de la anatomía macroscópica.

Veterinary gross anatomy is a branch of morphology aimed at studying the normal characteristics of the animal body. The teaching-learning processes have used various resources, from a traditional teaching cadavers fixed in formalin to a complementation with multimedia materials. As a result of the continued decline of the classroom hours participation in the curricula of veterinary medicine, this article shows a number of methodologies used in both veterinary and human anatomy by various authors. Each one has advantages and disadvantages their integration however, enhances student understanding. As authors we advocate this integration without veering from the use of cadavers and current veterinary anatomical terminology as the main teaching resources in the process of teaching and learning gross anatomy.

Prevalencia del uso de epónimos en publicaciones y ponencias del 18th Congress of International Federation of Associations of Anatomists 2014 / Eponyms prevalence in publications and presentations at the 18th Congress of International Federation of Associations of Anatomists 2014

La Terminologia Anatomica se usa internacionalmente como referente de los términos propios de la morfología, en la que no se utilizan epónimos, pues no hacen referencia a ningún detalle anatómico ni funcional relevante, pero sí traen a la memoria los nombres de personas, complejizando el aprendizaje y la comunicación. El objetivo del presente trabajo fue estudiar la prevalencia de epónimos usados durante la realización del 18th Congress of International Federation of Associations of Anatomists, realizado en Beijing -China- en el año 2014. Se analizaron aleatoriamente cinco presentaciones orales y las trescientas presentaciones formales en la modalidad de poster durante el congreso, buscando el uso de epónimos. Aunque hubo un porcentaje muy bajo de utilización de epónimos durante el 18th Congress of International Federation of Associations of Anatomists, no se justifica que el comité científico de dicho evento haya aceptado tales trabajos. Quizá esto podría considerarse como un obstáculo a la función que cumple la Federal International Committee on Anatomical Terminology.

The Anatomical terminology is used internationally as a reference of the specific terms of morphology, in which no eponyms are used, because they make no reference to any relevant anatomical or functional detail, but it does bring to mind the names of people, making the learning and communication more difficult. The aim of this work was to study the prevalence of eponyms used during the 18th Congress of International Federation of Associations of Anatomists, held in Beijing in 2014. -China-: five oral presentations were analyzed randomly and the three hundred formal presentations in the poster modality during the congress, seeking the use of eponyms. Although there was a very low percentage of use of eponyms during 18th Congress of International Federation of Associations of Anatomists, is not justified that the scientific committee of the event has accepted such works. Perhaps this could be seen as an obstacle to the role of the Federal International Committee on Anatomical Terminology.

Anatomic description of the ulna of the white-footed tamarin (Saguinus leucopus Günther, 1876) / Descripción anatómica de la ulna del tití gris (Saguinus leucopus Günther, 1876)

This document is a description of the macroscopic functional anatomy of the ulna bony prominences in the White-footed Tamarin (Saguinus leucopus), a neotropical endemic, and monotypic primate of Colombia. Few studies have been conducted on its anatomy, and thus its ulnar morphology, an essential element for this animal's quadrupedal arboreal locomotion, remains unknown. This study is based on eight specimens, fixed in formalin at 10 % whose ulnas were extracted in order to describe the main bony prominences along with muscular and ligamentous fixation functions. These elements of the locomotor apparatus and the multiple anatomical contours of the ulna of the White-footed Tamarin, exhibit characteristics for positional and articular adjustment with other bones of the forelimb in harmony with the attachments of the muscles, essential for quadrupedal arboreal locomotion.

El presente trabajo es una descripción de la anatomía macroscópica y funcional de los relieves óseos de la ulna del tití gris (Saguinus leucopus), un primate neotropical, endémico y monotípico de Colombia, con escasos estudios sobre su anatomía, y por ende de la morfología ulnar, elemento fundamental para la locomoción cuadrúpeda de este animal arbóreo que permanece desconocida. Para ello, se tomaron como base del estudio ocho especímenes fijados con formalina al 10 % y de ellos se extrajeron sus ulnas, describiendo los principales relieves óseos con sus funciones de fijación muscular y ligamentosa. Estos elementos del aparato locomotor con sus múltiples relieves anatómicos de la ulna del tití gris, presentan características para la adaptación posicional y articular con otros huesos del miembro torácico de manera armónica para la fijación de músculos indispensables en su locomoción cuadrúpeda arbórea.

Descriptive anatomy of lateral digital extensor muscles of the hand of the white-footed tamarin (Saguinus leucopus Günther, 1876) / Anatomía descriptiva de los músculos extensores digitales laterales de la mano del tití gris (Saguinus leucopus Günther, 1876)

The Saguinus leucopus is an endemic and monotypic primate of Colombia with quadrupedal arboreal locomotion, but the study of its morphological adaptations are still scarce, therefore the specific knowledge of its muscles will allow to understand these adaptations and to establish better medical and surgical procedures in order to preserve this species. For this purposes, the two forearms of 10 S. leucopus specimens were dissected, they were fixed within a formaldehyde solution, phenic acid and mineral oil mixture. Among the craniolateral muscles of the forearm two muscles were independent for digits IV and V. They presented form, origin and insertion suitable for individual extension of each digit, with innervation and irrigation by the cranial interosseous nerve and the homonymous artery respectively; they show similarities and differences with other primates, it allows to conclude that the development of these muscles could enable a particular anatomical and functional individualization in these digits extension, this feature makes possible its quadrupedal arboreal locomotion.

El Saguinus leucopus es un primate endémico y monotípico de Colombia con la locomoción cuadrúpeda arbórea, sin embargo los estudios de sus adaptaciones morfológicas aún son escasos, por lo tanto, el conocimiento específico de sus músculos permitirá conocer estas adaptaciones y establecer mejores procedimientos médicos y quirúrgicos con el fin de preservar esta especie. Para estos fines, se disecaron los dos antebrazos de 10 especímenes de S. leucopus, los cuales fueron fijados con una solución en mezcla de formaldehído, aceite mineral y ácido fénico. Entre los músculos cráneo laterales del antebrazo se encontraron dos músculos independientes para los dígitos IV y V. La forma, el origen y la inserción eran adecuadas para la extensión individual de cada dígito, con la inervación e irrigación por el nervio interóseo craneal y la arteria del mismo nombre respectivamente, presentando similitudes y diferencias con otros primates, lo que permite llegar a la conclusión que el desarrollo de estos músculos podría permitir una individualización anatómica y funcional particular en la extensión de estos dígitos, haciendo posible su locomoción cuadrúpeda arbórea.

El nervio craneal cero (nervio terminal): una visión interdisciplinaria entre la neuroanatomía y la neurofisiología / The cranial nerve zero (terminal nerve): an interdisciplinary view of neuroanatomy and neurophysiology

Introducción: en la Terminologia Anatomica Internacional se encuentra incluido el término nervio terminal, también conocido como nervio craneal cero; sin embargo no aparece referenciado en los textos de fisiología, lo que denota una disociación entre estos campos del conocimiento de las ciencias básicas. Una integración o acercamiento entre estos dos campos del conocimiento, permitiría una mejor comprensión de la estructura y función de este nervio. Metodología: se revisaron diversos textos y artículos de fisiología para determinar si hay estudios fisiológicos o anotaciones que hagan referencia a la función del nervio terminal y se integraron al conocimiento morfológico existente. Discusión: aunque gran parte de la neuroanatomía macroscópica y la histología del nervio terminal han sido descritas, en el campo de la fisiología existe mucho desconocimiento acerca de este nervio y muchas de sus anotaciones funcionalesse basan en supuestos. No obstante, se ha demostrado que es un pasaje para la migración de neuroblastos, de ahí que su estructura pudiera estar organizada en dospartes: una ahuecada para la migración neuroblástica y otra compacta de elementospara la propagación de potenciales de acción. Conclusión: el nervio terminal está constituido por fibras nerviosas con función autónoma desconocida y, rodeándolo, un compartimiento a manera de conducto migratorio de neuroblastos.

Introduction: in the international Terminologia Anatomica the term nervus terminalisor cranial nerve zero is included. How ever it does not appear, referenced in physiologytexts, which indicates dissociation between these fields of knowledge of basic science. An integration and rapprochement between these two fields of knowledge enable abetter understanding of the structure and function of this cranial nerve. Methodology: many physiology texts and articles were reviewed to determine whether physiological studies or notations referring to nerve terminal function and integrated to the existing morphological knowledge. Discussion: although much of the gross neuroanatomy and histology of the nervus terminalis have been described, in the field of physiology there is much ignorance about this nerve and many of their functional annotations are based on assumptions. How ever, it has proven to be a passage for the migration of neuroblasts, and thus its structure could be organized into two parts: a hollow for neuroblast migration and other elements for propagation of action potentials. Conclusion: the nervus terminalis is composed of nerve fibers with unknown function autonomously and, surrounding it, a compartment by way of conduit migratory neuroblasts.

Descripción anatómica del músculo extensor del I y II dedo de la mano del zorro perruno (Cerdocyon thous Linnaeus, 1766) / Anatomical description of crab-eating fox' (Cerdocyon thous Linnaeus, 1766) extensor of digit i and ii muscle

El zorro perruno (Cerdocyon thous) es el cánido silvestre más común en América del Sur, con una relativa estabilidad poblacional, pero susceptible de ser atropellado y caer en trampas, pudiendo sufrir traumas en sus miembros torácicos, por lo tanto se requiere un conocimiento anatómico específico de sus músculos para intervenciones médicas y quirúrgicas. El objetivo principal de esta investigación fue realizar una descripción anatómica del músculo extensor del I y II dedo del C thous, en la cual, se reporta forma, origen, inserción, inervación e irrigación. Se diseccionaron de superficial a profundo los dos antebrazos de seis especímenes muertos donados por CORPOCALDAS a la Universidad de Caldas. El músculo extensor del I y II dedo en este estudio presentó características anatómicas similares a las reportadas a otras especies pero con una distribución tendinosa variante formando desde tres a cuatro ramas que se distribuyen del I al III dedo, incluso faltando a veces para el III dedo, pero de igual forma presenta una distribución que debe ser conocida para procedimientos que requieran de su conocimiento.

The crab-eating fox (Cerdocyon thous) is the most common wild canid in South America. With a relative demographic stability, this animal is susceptible of being hit and falling into traps, and can suffer trauma in its thoracic limbs; therefore a specific anatomical knowledge about its muscles is necessary for medical and surgical procedures. The main aim of this research was to describe the anatomy of the extensor muscle of digit I and II of the C. thous reporting form, origin, insertion, innervation and irrigation. The forearms of six donated dead specimens from CORPOCALDAS to Caldas University were dissected from superficial to deep. In this research, the extensor muscle of digit I and II showed similar anatomical features to those reported for other species but with a variant tendinous distribution that forms from three to four branches distributed from digit I to III. Although sometimes this distribution does not exist for the digit III; this similar distribution must be reported for procedures which require this knowledge.

Descripción anatómica del músculo braquiorradial del tití gris (Saguinus leucopus Günther, 1877) y el hallazgo de una cabeza accesoria como variante anatómica / Anatomical description of white-footed tamarin (Saguinus leucopus Günther, 1877) brachioradialis muscle, and the finding of an accessory head as an anatomical variant

El Saguinus leucopus es un primate neotropical, endémico y monotípico de Colombia, con escasos estudios sobre su anatomía, en especial de sus músculos, siendo estos un elemento fundamental para la locomoción activa de este primate en los árboles. El objetivo del presente estudio fue describir la anatomía macroscópica del músculo braquiorradial del tití gris (Saguinus leucopus), tomando como base del estudio diez especímenes fijados con formalina al 10%, y a cada uno de ellos se les disecó los dos miembros torácicos de superficial a profundo, describiendo la forma, el origen, la inserción, la inervación y la irrigación del músculo braquiorradial. Se concluye que es un músculo que presenta una morfología, que debe contribuir a los movimientos flexores y supinadores del codo, y puede llegar a tener una cabeza accesoria en esta especie.

The Saguinus leucopus is a neotropical, endemic, and monotypic Colombian primate; few studies have been reported about its anatomy, specially about its muscles, this being a fundamental element for the active motion of this primate in the trees. The aim of this study was to describe the gross anatomy of the brachioradialis muscle on the white-footed tamarin (Saguinus leucopus). Ten specimens were included in the study, fixed with formalin at 10% and their thoracic limbs dissected, from the superficial to the deep plane, describing the form, origin, insertion, innervation and irrigation of the Brachioradialis muscle. The conclusion we made is that this muscle represents a morphology and in this way it must contribute to the flexor and supinator elbow movements, and would have an accessory head in this species.