Assuntos
Antebraço , Granuloma Anular/diagnóstico , Administração Oral , Idoso de 80 Anos ou mais , Anti-Inflamatórios/administração & dosagem , Feminino , Granuloma Anular/tratamento farmacológico , Granuloma Anular/patologia , Humanos , Injeções Intralesionais , Triancinolona/administração & dosagem , Vitamina E/administração & dosagemAssuntos
Dermatoses Faciais/diagnóstico , Foliculite/diagnóstico , Nariz/patologia , Pseudolinfoma/diagnóstico , Adulto , Biópsia , Diagnóstico Diferencial , Dermatoses Faciais/patologia , Dermatoses Faciais/cirurgia , Neoplasias Faciais/diagnóstico , Feminino , Foliculite/patologia , Foliculite/cirurgia , Humanos , Pseudolinfoma/patologia , Pseudolinfoma/cirurgiaRESUMO
We describe the case of a 44-year-old homosexual man diagnosed with HIV infection and visceral leishmaniasis. He presented nodules on the dorsum of the hands. Histological study of one of the nodules revealed necrobiotic palisading granulomas with abundant Leishmania amastigotes within the histiocytes and in the adjacent extracellular space. Tissue and peripheral blood cultures were positive for Leishmania infantum, zymodeme MON-24. A biopsy of healthy skin did not reveal the presence of Leishmania. A diagnosis of rheumatoid nodulosis with Leishmania was made and treatment was started with intravenous liposomal amphotericin, leading to slight improvement. We believe that the presence of the parasite within the nodules was the result of its dissemination during visceral leishmaniasis in an immunocompromised patient with HIV infection, and that the Leishmania did not have an etiological role in the appearance of the nodules. We present the first case of the association between Leishmania and rheumatoid nodulosis.
Assuntos
Granuloma/etiologia , Infecções por HIV/complicações , Dermatoses da Mão/etiologia , Leishmania infantum/isolamento & purificação , Leishmaniose Visceral/complicações , Parasitemia/etiologia , Nódulo Reumatoide/etiologia , Adulto , Animais , Animais Domésticos/parasitologia , Biópsia , Cães/parasitologia , Granuloma/parasitologia , Dermatoses da Mão/parasitologia , Humanos , Queratinócitos/parasitologia , Masculino , Parasitemia/parasitologia , Nódulo Reumatoide/parasitologiaAssuntos
Carcinoma Verrucoso/diagnóstico , Neoplasias Faciais/diagnóstico , Neoplasias Cutâneas/diagnóstico , Idoso , Biópsia , Carcinoma Verrucoso/etiologia , Carcinoma Verrucoso/patologia , Carcinoma Verrucoso/cirurgia , Sondas de DNA de HPV , Diagnóstico Diferencial , Neoplasias Faciais/etiologia , Neoplasias Faciais/patologia , Neoplasias Faciais/cirurgia , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias Induzidas por Radiação/diagnóstico , Neoplasias Induzidas por Radiação/patologia , Neoplasias Induzidas por Radiação/cirurgia , Neoplasias Cutâneas/etiologia , Neoplasias Cutâneas/patologia , Neoplasias Cutâneas/cirurgiaAssuntos
Eritema/etiologia , Hidradenite/etiologia , Doença de Hodgkin/complicações , Leucemia Neutrofílica Crônica/complicações , Síndromes Paraneoplásicas/complicações , Corticosteroides/uso terapêutico , Idoso , Feminino , Humanos , Neoplasias Cutâneas/tratamento farmacológico , Resultado do TratamentoRESUMO
Eosinophilic pustular folliculitis (EPF) is a rare, chronic disease of unknown cause, characterized by itchy papules or pustules and an infiltration of eosinophiles in the biopsy. EPF occurs rarely outside Japan and very few cases have been described in non-Japanese race people. The causes of the disease and its definitive treatment have not yet been established. In our patient, the presence of subcorneal pustules in the biopsies initially favored a diagnosis of pustulosis and several biopsies were necessary before a diagnosis of EPF was reached. A new case of EPF recently presented at our clinic and we have carried out an extensive revision of the disease.
Assuntos
Eosinofilia/patologia , Foliculite/patologia , Dermatopatias Vesiculobolhosas/patologia , Adulto , Feminino , HumanosRESUMO
BACKGROUND: Sweet's syndrome (SS) has been reported in association with many conditions, including malignancy, infections, autoimmune disorders, pregnancy and drugs. MATERIALS AND METHODS: We reviewed patients with SS-like lesions on the lymphoedema area seen in our department. Clinical manifestations, histopathologic characteristics, treatment and outcome data were recorded and analysed. RESULTS: We report seven women with a history of surgery for breast cancer with axillary lymphadenectomy. Six of them were on tamoxifen. All of them had various lesions consistent with SS localized predominantly on the limb affected by the postmastectomy lymphoedema, and on the ipsilateral chest, trunk and back. One of them presented bullous lesions. Three of the cases underwent spontaneous remission, two resolved with antibiotic therapy, one healed with corticosteroids, and one with corticosteroids plus antibiotic. CONCLUSIONS: Erythematous tender plaques on the area of postmastectomy lymphoedema could be considered an unusual manifestation of Sweet's syndrome. We have found only three similar cases in the literature. Although it is difficult to elucidate the pathogenesis of this entity, it has been suggested that it could be due to immune surveillance impairment.