Comparison of Hemodynamic Stability and Pain Control in Lateral and Prone Positions in Patients Undergoing Percutaneous Nephrolithotomy: A Randomized Controlled Trial.

PURPOSE: Percutaneous nephrolithotomy (PCNL) is the preferred surgical treatment in many cases of kidney stones which is performed in different positions such as prone, lateral, and supine. This study was designed to evaluate whether patient position (lateral versus . prone) has an effect on the need for analgesia and onset of pain after surgery. MATERIALS AND METHODS: Patient with confirmed kidney stones (size ? 2 cm) who were candidates for PCNL were enrolled in this study. The required biochemical analyses were performed preoperatively. All patients  underwent spinal anesthesia by the same anesthesiologists and then were randomly divided into two separate groups as lateral (L) and prone (P) positions. The operations' start and end time, required time for proper access into target calyces, additional need for analgesic or cardiac drugs, duration of analgesia, and onset of pain after PCNL were carefully recorded and then compared between the two groups. RESULTS: In total, 51 patients were evaluated of whom 39 were men and 12 were women. Mean duration of analgesia after PCNL surgery in P group (173 ± 8 min) was significantly longer than in L group (147±12 min) (P = .001). Furthermore, the amount of ephedrine usage in L group (3.6 ± 1.5mg) was significantly lower than in the P group (16.4 ± 12mg), suggesting more hemodynamic variations in the P group during the operation. CONCLUSION: Our randomized control trial study shows that choosing the optimal position in the PCNL technique depends on  patient's condition. If hemodynamic control is of matter to the anesthesiologist, then lateral position is more appropriate. However, if control of pain and longer time of analgesia are important,  prone position may be preferred.

Comparison of percutaneous nephrolithotomy under spinal versus general anesthesia: a randomized clinical trial.

PURPOSE: To evaluate the safety and efficacy of spinal anesthesia compared with general anesthesia in patients who underwent percutaneous nephrolithotomy (PCNL). PATIENTS AND METHODS: One hundred patients with American Society of Anesthesiologists (ASA) score <3 were randomly divided into two groups according to the type of anesthesia. Spinal anesthesia was performed using an injection of 0.25 mg/kg bupivacaine 0.5% in the intrathecal space; no opium (fentanyl) agent was used. All procedures were performed with the patient in the prone position. Stone access was made by using fluoroscopic guidance, and the tract was dilated using a single-stage technique. All patients received a solution including 1 mg/kg morphine in every 100 mL physiologic saline through the volumetric pump during the 3-hour post-PCNL period in the recovery room. Afterward, morphine (0.05 mg/kg) was injected only according to the verbal rating scale greater than 3 after discharge from the recovery room until 24 hours after surgery. RESULTS: The two groups were matched by mean age, distribution of stone location, and stone burden. Mean operative time, hospital stay, stone-free rate and mean hemoglobin drop were comparable between the two groups. The rate of complications according to the Clavien grading system was nearly similar in both groups. Mean analgesic requirement during 24 hours after PCNL was 6.8 mg in the spinal group and 13.2 mg in the general group (P<0.001). CONCLUSION: It seems that using spinal anesthesia by intrathecal injection of local anesthetic solutions vs general anesthesia has comparable surgical outcomes and reduces the requirement for analgesia after PCNL in the early postoperative period.

Comparison of acromioaxillosuprasternal notch index (a new test) with modified Mallampati test in predicting difficult visualization of larynx.

BACKGROUND: We aimed to compare the efficacy of a new bedside screening test named acromioaxillosuprasternal notch index (AASI) with modified Mallampati (MMP). METHODS: A total of 603 adult patients, who were candidates for tracheal intubation in elective surgery, were enrolled in this prospective study. Preoperative airway assessment was carried out with AASI and MMP. The new AASI score is calculated based on the following measurements: (1) using a ruler, a vertical line is drawn from the top of the acromion process to the superior border of the axilla at the pectoralis major muscle (line A); (2) a second line is drawn perpendicular to line A from the suprasternal notch (line B); and (3) the portion of line A that lies above the point where line B intersects it is line C. AASI is calculated by dividing the length of line C by that of line A (AASI = C/A). After induction of anesthesia, the laryngeal view was recorded according to the Cormack-Lehane grading system. Receiver operating characteristic curve analysis was employed to compare between AASI and MMP. RESULTS: Difficult visualization of larynx (DVL, Cormack-Lehane III and IV) was observed in 38 (6.3%) patients. The best cutoff point for DVL was defined at AASI > 0.49. AASI had a lower false negative rate and higher predictive values (sensitivity, positive predictive value, and accuracy) in comparison with MMP. CONCLUSION: AASI was associated with higher predictive values than MMP and could be used for estimation of DVL.

Comparing vertical and coracoid approaches for infraclavicular block in orthopedic surgery of the forearm and hand.

STUDY OBJECTIVE: To determine if there is a difference between the vertical and coracoid approaches to the infraclavicular block. DESIGN: Randomized, double-blinded clinical trial. SETTING: University-affiliated medical center. PATIENTS: 60 ASA physical status 1 and 2 patients undergoing surgery of the forearm and hand. INTERVENTIONS: Patients were randomized to two groups: Group VIP (vertical infraclavicular approach; n=30) and Group Coracoid (coracoid infraclavicular approach; n=30). In the infraclavicular coracoid approach, the coracoid process was used as the landmark. Needle positioning was guided by nerve stimulation. MEASUREMENT: For each approach, the quality of sensory and motor block was assessed and recorded separately for each of the 4 major nerves of the upper limb. MAIN RESULTS: The infraclavicular coracoid approach (11±1 min) was faster to perform than the vertical infraclavicular block (14±1 min; P < 0.05). The infraclavicular coracoid approach yielded a shorter sensory block onset time (2.3±1.3 vs 3±1.3 min; P < 0.05). In the coracoid group, a pronounced sensory and motor block was noted in the area innervated by the musculocutaneous nerve (P < 0.05). CONCLUSION: The coracoid approach is convenient to perform with extensive block, and is thus an appropriate alternative to the vertical approach in infraclavicular block.

Use of laryngeal mask airway in children with upper respiratory tract infection, compared with face mask: randomized, single blind, clinical trial.

OBJECTIVE: The incidence of postoperative cough (primary outcome) and adverse respiratory events (secondary outcome) in children who received anesthesia by laryngeal mask airway (LMA) with children who received anesthesia by face mask (FM) was compared in a blind randomized trial with uncomplicated upper respiratory track infection (URI) undergoing general anesthesia. Previous studies of pediatric patients with URI receiving anesthesia by endotracheal tube have reported a greater number of anesthetic complications; however reports concerning adverse effects in pediatric patients with URI receiving anesthesia by LMA or FM are scanty. METHOD: For the present trial, 150 children with uncomplicated URI and requiring general anesthesia for ophthalmic procedures were enrolled. Once the severity of preoperative URI symptoms was stratified, the children were randomized to receive general anesthesia by FM or LMA. Anesthesia was induced with sevoflurane and nitrous oxide in oxygen (N(2)O in O(2)). Respiratory adverse events were evaluated peri- and post-operatively. RESULTS: The two groups did not differ in age, weight, American Society of Anesthesiologists (ASA) physical status, sex, duration of surgery or severity of URI symptoms. The incidences of cough (19% in LMA vs. 42% in FM), vomiting (4% in LMA vs. 12% in FM) and intervention to maintain the patency of the airway were statistically higher in the FM group (p<0.05). There were no differences between the two groups with respect to the incidences of apnea, laryngospasm, desaturation, bronchospasm, readmission and sore throat. CONCLUSION: In children with uncomplicated URI, the administration of inhalation anesthetics in general anesthesia by LMA is likely to cause fewer adverse events than the use of FM.

A rapidly enlarging neck mass: the role of the sitting position in fiberoptic bronchoscopy for difficult intubation.

Difficult airway management is a dilemma for any anesthesiologist. Although practice guidelines and algorithms may help in such situations, the anesthesiologist's judgment and vigilance remain the primary means to save lives. In the following case, we encountered an acutely enlarging thyroid mass that was compromising the airway. This huge neck mass precluded tracheostomy under local anesthesia, and the patient could breathe only in the sitting position. Therefore, there were few safe strategies for airway management for general anesthesia. We reiterate the role of awake fiberoptic intubation in such circumstances.

The contribution of diabetes mellitus per se to the severity of coronary artery disease.

BACKGROUND: Coronary artery disease (CAD) is the most common chronic, life-threatening illness in many Western countries. The risk factors associated with diabetes mellitus and the metabolic syndrome in diabetics are generally considered more important in the evolution of CAD than the diabetic state itself. AIM: This study was undertaken to determine the contribution of diabetes mellitus to the characteristics and severity of coronary artery disease among young patients. METHODS: Thirty diabetics (group 1) were selected from a group of young patients (