The effect of maternal organic manganese supplementation on performance, immunological status, blood biochemical and antioxidant status of Afshari ewes and their newborn lambs in transition period.

It has been documented that adequate maternal manganese (Mn) status is vital for performance and health of ewes and their newborn lambs. However, required level and form of dietary Mn in ruminants are not well defined. The current study was conducted to evaluate the effect of maternal organic Mn supplementation on performance, immunological status, blood biochemical and antioxidant status of Afshari ewes and their newborn lambs in transition period. For this purpose, various organic Mn concentrations were utilized as a supplementary ingredient in formulating the diets of ewes. The ewes were randomly allocated into three groups, fed with 0, and 80 mg/kg organic Mn supplemented diet. At the end of the experiment, the parameters including the performance of newborn lambs, as well as biochemical factors, immune status and antioxidant status in ewes and their newborn lambs were evaluated. The results showed a significant increase in the plasma concentrations of Mn, glucose, insulin, thyroid hormones (T3 , T4 ) and enzymatic antioxidants (SOD, GPX , CAT) in ewes and their newborn lambs that were treated with maternal organic Mn. Moreover, inorganic Mn treatments, the concentration of IgG in newborn lamb's plasma, and colostrum of ewes increased. According to this research, organic Mn acts as a valuable and safe supplementary material that could be exploited for enhancing health of ewes and their newborn lambs.

Effects of dietary curcumin nano-micelles on growth performance, blood metabolites, antioxidant status, immune and physiological responses of fattening lambs under heat-stress conditions.

The aim of the current study was to investigate the effects of dietary curcumin nano-micelles (C-NM) on the growth performance, blood metabolites, antioxidant status, and immune and physiological responses of fattening lambs under heat stress conditions. Thirty-two crossbred male lambs [Île-de-France × (Dalagh × Romanov)] with an average weight of 31.2 ± 1.55 kg and age of 4-5 months were assigned to experimental treatments in a completely randomized design including four treatments and eight replications. The treatments were T0, T20, T40, and T80, representing dietary supplementation of C-NM at 0, 20, 40, and 80 mg per head per day, respectively. The study lasted for 37 days including 7 days of adaptation period. Lambs were weighed on days 0 and 30 of the experiment before morning feeding to determine the average daily gain (ADG) and feed conversion ratio (FCR). Blood samples were collected from the jugular vein on day 30 of the experiment and physiological parameters, including rectal temperature (RT), skin temperature (ST), respiration rate (RR), and pulse rate (PR), were measured once a week on a certain day during the study. Lambs in the T40 group showed higher final live weight (FLW) and ADG, while exhibiting lower FCR (P < 0.01). Regression analysis predicted the optimum levels of dietary inclusion of C-NM to be 44.7, 38.3, and 42.0 mg/day for FLW, ADG, and FCR, respectively. Dietary supplementation of C-NM decreased RT, ST, and RR, while increasing PR (P < 0.01). The levels of immunoglobulins G (IgG) and A (IgA) increased linearly with the dietary inclusion of C-NM (P < 0.01), while levels of immunoglobulin M (IgM) remained unaffected (P > 0.05). Dietary inclusion of C-NM had a quadratic reducing effect on the serum concentration of malondialdehyde (MDA) and a cubic increasing effect on the serum activities of glutathione peroxidase (GPx) (P < 0.05). Superoxide dismutase (SOD) was linearly increased in T80, while total antioxidant capacity (TAC) showed a linear increase in T40 and T80 groups (P < 0.01). Based on the results of this study, we recommend the administration of C-NM in the diet of fattening lambs during hot months in tropical and subtropical areas. However, further studies are needed to assess the long-term effects of C-NM during various physiological and production statuses.