Sclerosing sweat duct carcinoma mimicking dermatofibroma.

Sclerosing sweat duct carcinoma is an infrequent adnexal tumor, locally aggressive and with a high incidence of local recurrences. Its location is preferably cephalic and its clinical presentation often unspecific. We present a new case with an atypical location and the clinical appearance of a benign cutaneous lesion. Diagnosis was established after a histological and immunohistochemical study. A terminological review was done.

Spontaneous regression of Merkel cell carcinoma of the skin.

We report a 65-year-old man who presented with a Merkel cell carcinoma on his right ear, a small satellite nodule and regional lymph node metastases. No treatment was given because of his generally poor state of health. Spontaneous regression of all the lesions was observed within a month. Merkel cell carcinoma is a potentially aggressive tumour. Only four cases of spontaneous regression have been reported previously.

Cutaneous leiomyosarcoma in a child.

Superficial leiomyosarcomas are infrequent tumors that are very rare in childhood. We report on a 12-year-old white boy with a cutaneous leiomyosarcoma of his left groin. Immunohistochemical study revealed positive immunostaining with antibodies to vimentin, desmin, and smooth muscle actin. The tumor was removed with wide surgical margins.

Pachydermodactyly: report of two cases.

Pachydermodactyly is a rare and benign form of digital fibromatosis with only a few cases described in the literature. We report two cases of pachydermodactyly affecting young men. In one of them a knuckle pad was found, and the fibromatous thickening of the skin affected not only the finger joints but also the dorsum of the hands. This case can be included in the particular clinical form named pachydermodactyly transgrediens.

[Multiple clustered histiocytofibroma. Apropos of a case with immunohistochemical study]. / Histiocytofibromes multiples groupés. A propos d'un cas avec étude immunohistochimique.

Multiple clustered dermatofibromas constitute an uncommon entity, of which we have collected seven cases in the literature. We observed the case of a 4-year-old girl, who had dermatofibromas confluent in a central plaque of fibrous aspect, located in the lumbar region. The immunohistochemical study showed positive staining for Factor XIIIa antibody, confirming its origin in the dermal dendrocyte.

Benign cephalic histiocytosis--study of a case.

Benign cephalic histiocytosis is a rare, benign, self-healing form of non-X histiocytosis. A case in a 3-month-old girl is reported. The papular eruption involved her face, neck, shoulders and upper trunk. Light and electron microscopic findings and clinical evolution confirmed the diagnosis. The differential diagnosis with the micronodular form of juvenile xanthogranuloma is discussed.

[Familial eosinophilic fascitis induced by toxic oil]. / Fascitis eosinofílica familiar inducida por aceite tóxico.

Three of four family members in husband, wife and one of two daughters developed in a short time interval (eleven months) eosinophilic fasciitis. The clinical, analytical and histopathological changes were characteristic of this disease. Familial cases of eosinophilic fasciitis have not been previously published. The process of these patients was probably caused by the ingestion of denatured oil (toxic oil syndrome), although the clinical picture begun two and a half years after the epidemic phase of the toxic oil syndrome declined.

[Bowenoid papulosis in a patient with AIDS]. / Papulosis bowenoide en paciente de SIDA.

A patient with a acquired immunodeficiency syndrome (AIDS) and Kaposi's angiosarcoma developed bowenoid papulosis of the genitalia (BP). The clinical and histopathological criteria were both characteristic of BP. With vinblastine treatment a moderate improvement of Kaposi's lesions was observed, but no significant changes of the BP lesions were noted during this treatment.