Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros











Base de dados
Intervalo de ano de publicação
1.
Biomed Res Int ; 2024: 9543897, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39026517

RESUMO

Selective neck dissection (SND) is the treatment of choice in patients with oral squamous cell carcinomas (OSCCs) and clinically node-negative necks (cN0). The treatment of patients with positive-staged necks (cN+) includes SND as well as comprehensive neck dissection (CND). The clear benefit of one or the other remains under debate. We aim to address this lack of clarity by analysing patients with OSCC staged with clinically node-positive necks, treated with either CND or SND using a level-by-level approach. This retrospective study included patients diagnosed with OSCC with clinically (cN+) and pathologically (pN+) positive cervical lymph nodes (LNs) with clear neck level categorization during the years 2010-2019. In total, 74 patients were analysed. Cox regression analysis found no significance for the type of ND being an independent risk factor, neither for overall survival (OS) nor for disease-free survival (DFS). Regional recurrence of CND cases (5.77%) was comparable to SND cases (9.09%). For OS, extracapsular spread (ECS) and male sex were identified as independent risk factors with poorer outcome. pT-stage and ECS were found to be independent risk factors for DFS. The results of this study suggest that both CND and SND may be viable treatment options for certain patients with OSCC pN+.


Assuntos
Carcinoma de Células Escamosas , Linfonodos , Metástase Linfática , Neoplasias Bucais , Esvaziamento Cervical , Humanos , Masculino , Feminino , Neoplasias Bucais/cirurgia , Neoplasias Bucais/patologia , Neoplasias Bucais/mortalidade , Pessoa de Meia-Idade , Esvaziamento Cervical/métodos , Idoso , Estudos Retrospectivos , Adulto , Intervalo Livre de Doença , Linfonodos/patologia , Linfonodos/cirurgia , Carcinoma de Células Escamosas/cirurgia , Carcinoma de Células Escamosas/patologia , Resultado do Tratamento , Recidiva Local de Neoplasia/patologia , Idoso de 80 Anos ou mais , Fatores de Risco
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA