1.
J Pediatric Infect Dis Soc
; 8(1): 73-76, 2019 Mar 28.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29415165
RESUMO
Single gene defects that impair lymphocyte cytotoxicity can predispose to severe viral infection that normally remains subclinical. The classic severe presentation is hemophagocytic lymphohistiocytosis. Here, we report the case of a neonate who presented with cytomegalovirus palatal ulceration and bocavirus pneumonitis secondary to impaired cytotoxicity caused by biallelic mutations in the UNC13D gene.