Aerobic exercise training reduces deep-frying oil-induced apoptosis of hippocampal tissue by reducing oxidative stress in male rats.

Deep-frying oil (DFO) contains high amounts of free radicals, and consuming foods prepared with this method causes damage to nervous tissue due to oxidative stress (OS). Since moderate-intensity aerobic exercise training (AT) reduces OS, the current search investigated the effects of AT on OS, apoptosis, and neurogenesis markers in the hippocampal tissue of DFO-fed rats. Eighteen Wistar male rats (200-280 gr) were randomly allocated to a control group fed with normal food (Con-ND), a control group receiving DFO (Con-DFO), and a group receiving DFO-aerobic exercise (EX-DFO) (n = 6 in each). DFO was gavaged for four weeks, five days a week, with a dose of 2 ml. AT included running on a treadmill for four weeks and five sessions per week (40 min per session). The expression of genes B-cell lymphoma 2 (BCL-2), Protein X associated with Bcl-2 (BAX), Caspase-3 (Casp-3), and Caspase-9 (Casp-9) was measured by PCR method. The ELISA method was used to calculate levels of Superoxide dismutase (SOD) and Catalase (CAT) activity, malondialdehyde (MDA), and Brain-Derived Neurotrophic Factor (BDNF). Also, the expression of the proteins Cannabinoid receptor type 1(CB1), Cannabinoid receptor type2 (CB2), Glial fibrillary acidic protein (GFAP), Neuronal nuclei (NeuN), and DNA fragmentation was evaluated by Immunohistochemical and TUNEL staining. DFO feeding led to a significant increase in apoptotic markers, such as BAX, Casp-3, and Casp-9 gene expression, and DNA fragmentation (p ≤ 0.05) while decreasing BDNF concentration SOD activity (p ≤ 0.05). AT significantly reduced the BAX, Casp-3, Casp-9, MDA, CB1, GFAP, and DNA fragmentation (p ≤ 0.05). In conclusion, AT can reduce the harmful effects of feeding with DFO on the hippocampal tissue.

Footprint measurement methods for the assessment and classification of foot types in subjects with Down syndrome: a systematic review.

BACKGROUND: Musculoskeletal disorders, especially in the feet, are common in people with Down syndrome (DS). Evaluation of podiatric footprints is important to prevent and manage orthopedic symptoms. The reliability of a wide variety of footprint measurement methods has been evaluated in healthy people, but few studies have considered the specific morphotype features of the feet in subjects with DS. The aim of this systematic review was to identify the podometric measurement tools used to typologically classify the footprints in the population with DS. METHODS: The following electronic databases were searched for studies describing footprint measurement tools to assess and classify the foot types in patients with DS published from inception to December 2020: PubMed, Web of Science, CINAHL, and Scopus. Articles were initially searched by screening titles and abstracts. Potentially relevant studies were then further screened by reviewing full texts. Studies that met the inclusion criteria were included in the review. RESULTS: Of the 122 articles identified by the search strategy, 14 full texts were retained to assess for eligibility, of which 11 studies met the inclusion criteria and were included. All the studies used footprint measurement methods to classify the foot types in subjects with DS, but only two studies assessed the reliability of those methods for the population with DS. The footprint measurement tools identified were a podoscope, a pressure-sensitive mat, a PressureStatTM carbon paper, and a 3D scanner. The Arch Index was the most common footprint measurement analyzed (seven studies). Two studies used the "gold standard" indexes that include Hernández-Corvo Index, Chippaux-Smirak Index, Staheli Index, and Clarke Angle to measure footprints. CONCLUSIONS: There is a need to determine the reliability and validity of the footprint measurement methods used for clinical classification of the foot types in subjects with DS. This can contribute to an early diagnosis of foot abnormalities that would help to reduce mobility impairments, improving the quality of life of patients with DS.

Construcción del registro de observación para el análisis del movimiento Fundamentado en la teoría de laban1 / Development Of An Observation Instrument For Recording Movement Analysis Based On Laban's Theory / Construção do registro de observação para a análise do movimento Fundamentado na teoría de laban

Resumen Barnet-López, S., Arbonés-García, M., Pérez-Testor, S. y Guerra-Balic., M. (2017). Construcción del registro de observación para el análisis del movimiento fundamentado en la teoría de Laban. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 15(2), 1-21. En este artículo se describe el proceso de construcción de un Registro de Observación inspirado en el Análisis del Movimiento de Laban (ROAM) en personas con Discapacidad Intelectual (DI). La aplicación del ROAM permite obtener una medida objetiva y estandarizada sobre las tendencias generales de movimiento de la persona, además de poder utilizarse en observaciones pre y post intervenciones y así conocer los cambios de movimiento del individuo. El del ROAM se desarrolló en varias fases, en la primera de las cuales se identificaron los elementos básicos para el registro y se realizaron diversas versiones del ROAM mediante la técnica de jueces expertos. En las fases posteriores se realizó el estudio exploratorio, utilizando el registro para evaluar dos sesiones de danza movimiento terapia en un grupo de adultos con DI. Los resultados muestran que el ROAM presenta unos buenos índices de validez de contenido y de fiabilidad inter e intra observadores (0.72), por tanto, el ROAM permitió analizar las características generales del movimiento de las personas con DI que participaron en el estudio exploratorio.

Abstract Barnet-López, S., Arbonés-García, M., Pérez-Testor, S. & Guerra-Balic., M. (2017). Development of an Observation Instrument for Recording Movement Analysis based on Laban's Theory. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 15(2), 1-21. This paper describes the development process of an observation record inspired in Laban's Movement Analysis (ROAM) for Intellectually Disabled (ID) people. An objective and standardized measurement of a person's general movement tendencies can be obtained from ROAM, in addition to making observations before and after an intervention, therefore learning about movement changes of an individual. The design of ROAM was developed in several stages: for the first one, basic elements were identified for the record and different versions of ROAM were created using the expert judges technique. Later stages involved an exploratory study, where two sessions of movement-dance therapy were evaluated in a group of ID adults using the record. Our results show that ROAM exhibits good indexes for content validity as well as intra- and inter-observer reliability (0.72). Thus, we conclude that ROAM allowed us to analyze the general movement characteristics of intellectually disabled individuals participating in this exploratory study.

Resumo Barnet-López, S., Arbonés-García, M., Pérez-Testor, S. & Guerra-Balic., M. (2017). Construção do registro de observação para a análise do movimento fundamentado na teoría de Laban. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 15(2), 1-21. Neste artigo se descreve o processo de construção de um Registro de Observação inspirado na Análise do Movimento de Laban (ROAM) em pessoas com Deficiência Intelectual (DI). A aplicação do ROAM permite obter uma medida objetiva e padronizada sobre as tendências gerais de movimento da pessoa, além de ser possível sua utilização em observações pré e pós intervenções e assim conhecer as mudanças de movimento do indivíduo. O desenho do ROAM foi desenvolvido em várias fases, na primeira das quais se identificaram os elementos básicos para o registro e realizaram diversas versões de ROAM através da técnica de juízes peritos. Nas fases posteriores foi realizado o estudo exploratório, utilizando o registro para avaliar duas sessões de dança movimento terapia em um grupo de adultos com DI. Os resultados mostram que o ROAM apresenta alguns bons índices de validade de conteúdo e de fiabilidade inter e intraobservadores (0,72), portanto, o ROAM permitiu analisar as características gerais do movimento das pessoas com DI que participaram no estudo exploratório.