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J Cardiovasc Electrophysiol ; 23(11): 1201-6, 2012 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-22734452

RESUMO

INTRODUCTION: Early recovery of conduction (ER) after cavotricuspid isthmus (CTI) ablation for typical atrial flutter (AFl) occurs in approximately 10% of the patients. If not recognized, ER might lead to AFl recurrences. In this study, we hypothesized that intravenous adenosine (iADO) can be used to predict ER in the CTI immediately after RF ablation and distinguish functional block from the complete destruction of the CTI myocardium. METHODS: We prospectively included 68 consecutive patients (age: 65 ± 14 years; male: 78%) referred in our centers for AFl ablation. Immediately after bidirectional isthmus block validation, a bolus of iADO was given during continuous pacing from the proximal coronary sinus. Patients with functional block revealed under iADO (iADO+) and those without (iADO-) were subsequently observed for a 30-minute waiting period (ER-) or until sustained recovery of the conduction through the CTI (ER+). RESULTS: Seven patients presented a persistent recovery (ER+, 10.3%, mean time to recovery: 14 ± 9 minutes). None of them presented even a transient resumption of conduction under iADO (iADO+: 0). With univariate analysis, we identified a heavy patient weight (>95 kg) as a predictor of ER (sensitivity: 71%). CONCLUSIONS: Adenosine does not predict early recovery in the CTI after linear ablation for atrial flutter. We found that a patient weight over 95 kg predicted early recovery of conduction through the CTI with a sensitivity of 71%.


Assuntos
Adenosina/administração & dosagem , Flutter Atrial/cirurgia , Ablação por Cateter , Técnicas Eletrofisiológicas Cardíacas , Valva Tricúspide/cirurgia , Idoso , Flutter Atrial/diagnóstico , Flutter Atrial/fisiopatologia , Peso Corporal , Estimulação Cardíaca Artificial , Ablação por Cateter/efeitos adversos , Distribuição de Qui-Quadrado , Feminino , Humanos , Infusões Intravenosas , Injeções Intravenosas , Masculino , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Estudos Prospectivos , Recidiva , Sensibilidade e Especificidade , Fatores de Tempo , Resultado do Tratamento , Valva Tricúspide/fisiopatologia
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