RESUMO
INTRODUCTION: Metastatic neoplasms to the vulva are rare and can pose a diagnostic dilemma. As identification of the primary site can influence patient treatment and prognosis, correct diagnosis is important. METHODS: PubMed was searched for applicable publications using the terms vulva, vulvar neoplasms, metastasis, and vulvar metastasis. RESULTS: Most neoplasms metastatic to the vulva originate from other genital sources; however, extragenital primary neoplasms can also metastasize to the vulva. Vulvar metastases often occur in the setting of widespread disease. CONCLUSIONS: It is important to consider biopsy for appropriate histologic and immunohistochemical studies, as well as consider patient history to establish the primary site of metastatic lesions to the vulva, allowing optimal therapy.
Assuntos
Vulva , Neoplasias Vulvares , Biópsia , Feminino , Humanos , Prognóstico , Vulva/patologia , Neoplasias Vulvares/diagnóstico , Neoplasias Vulvares/patologiaRESUMO
BACKGROUND: Although rare, pregnant women can present with fibroepithelial polyps of the vagina. Most likely hormonally related, these polyps have been described in various locations of the lower female genital tract. They can be mistaken for malignant lesions due to hypercellularity and cytologic atypia. CASE: We describe the case of a 31-year-old woman who presented with a polyp of the vagina during a postpartum visit. RESULTS: Atypical cells were seen in hypercellular areas of the stroma of the polyp. CONCLUSION: A pitfall to avoid is classifying these benign lesions as malignant based on atypical histopathology.
Assuntos
Pólipos/patologia , Complicações Neoplásicas na Gravidez/patologia , Neoplasias Vaginais/patologia , Adulto , Biomarcadores Tumorais/análise , Desmina/análise , Desmina/biossíntese , Feminino , Humanos , Imuno-Histoquímica , Gravidez , Receptores de Estrogênio/análise , Receptores de Estrogênio/biossíntese , Receptores de Progesterona/análise , Receptores de Progesterona/biossíntese , Vimentina/análise , Vimentina/biossínteseRESUMO
BACKGROUND: Specimens of endometrial biopsies can sometimes present with an artifact within blood, composed of optically clear vacuoles mimicking adipose tissue, pseudolipomatosis. This artifact can be mistaken for adipose tissue and lead to an overdiagnosis of uterine perforation. CASE: We describe the case of pseudolipomatosis seen within the evacuated products of conception from a missed abortion. RESULTS: Areas of vacuolization in the blood clot mimicked adipose tissue. However, the vacuoles varied in size and did not contain adipocytes. CONCLUSION: Familiarity with this artifact will lead to avoidance of overdiagnosis of adipose tissue and uterine perforation in curettage specimens.