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1.
Med Phys ; 36(6): 2172-80, 2009 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-19610306

RESUMO

Proton radiotherapy centers that currently use passively scattered proton beams do field specific calibrations for a non-negligible fraction of treatment fields, which is time and resource consuming. Our improved understanding of the passive scattering mode of the IBA universal nozzle, especially of the current modulation function, allowed us to re-commission our treatment control system for accurate delivery of SOBPs of any range and modulation, and to predict the output for each of these fields. We moved away from individual field calibrations to a state where continued quality assurance of SOBP field delivery is ensured by limited system-wide measurements that only require one hour per week. This manuscript reports on a protocol for generation of desired SOBPs and prediction of dose output.


Assuntos
Algoritmos , Radiometria/métodos , Radiometria/normas , Radioterapia Conformacional/instrumentação , Radioterapia Conformacional/normas , Desenho Assistido por Computador , Desenho de Equipamento , Análise de Falha de Equipamento , Terapia com Prótons , Dosagem Radioterapêutica , Reprodutibilidade dos Testes , Espalhamento de Radiação , Sensibilidade e Especificidade , Estados Unidos
2.
Med Phys ; 32(12): 3636-40, 2005 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-16475762

RESUMO

We have investigated methods of reconstructing beam profiles in the penumbral region using a set of axially symmetric chambers, differing only in the detector radius. In principal, the transfer functions, or kernels, of such chambers should be functions of radius only. Three chambers of radii 0.297, 0.556, and 0.714 cm have been used. The transfer functions of the chambers can be determined by deconvolving the profiles measured with each detector with the PPMC profile. The results indicate that the transfer functions can be parametrized accurately as a Gaussian cutoff at 1.75(r), with (r) the average radius of the chamber. Deconvolution of the measured profiles with the transfer functions yields a profile that agrees with the PPMC profile to +/- 0.5 mm over the 20-80% penumbra.


Assuntos
Radiometria/instrumentação , Fenômenos Biofísicos , Biofísica , Humanos , Matemática , Neoplasias/radioterapia , Interpretação de Imagem Radiográfica Assistida por Computador , Radiometria/estatística & dados numéricos , Planejamento da Radioterapia Assistida por Computador
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