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1.
J Oral Maxillofac Surg ; 81(9): 1146-1154, 2023 09.
Artigo em Inglês | MEDLINE | ID: mdl-37308089

RESUMO

BACKGROUND: An edema assessment following dental surgeries is essential to improving the dental surgeon's technique and, consequentially, patient comfort. PURPOSE: Two-dimensional (2D) methods are limited in analyzing 3-dimensional (3D) surfaces. Currently, 3D methods are used to investigate postoperative swelling. However, there are no studies that directly compare 2D and 3D methods. The goal of this study is to directly compare 2D and 3D methods used in the assessment of postoperative edema. STUDY DESIGN AND SAMPLE: The investigators implemented a prospective, cross-sectional study with each subject serving as its own control. The sample was composed of dental student volunteers without facial deformities. PREDICTOR VARIABLE: The predictor variable is the method used to measure edema. After simulating edema, manual (2D) and digital (3D) techniques were used to measure edema. The manual method used direct facial perimeter measurements. The two digital methods were photogrammetry using a smartphone (iPhone 11, Apple Inc, Cupertino, California), and facial scanning with a smartphone application (Bellus3D FaceApp, Bellus3D Inc, Campbell, California) [3D measurements] MAIN OUTCOME VARIABLE: The coefficient of variation (CV) (CV = standard deviation /mean) was used to assess homogeneity of edema measurements. ANALYSIS: The Shapiro-Wilk and equal variance tests were applied to assess data homogeneity. Next, one-way analysis of variance was performed, followed by a correlation analysis. Finally, the data were submitted to Tukey's test. The statistical significance threshold was set at 5% (P < .05). RESULTS: The sample was composed of 20 subjects aged 18-38 years. The CV showed higher values using the manual (2D) method (47%; 4.88% ± 2.99), compared with the photogrammetry method (18%; 8.55 mm ± 1.52) and the smartphone application (21%; 8.97 mm ± 1.93). A statistically significant difference was observed between the manual method values and those of the other two groups (P < .001). There was no difference between the facial scanning and photogrammetry groups (3D methods) (P = .778) CONCLUSION AND RELEVANCE: Both digital measuring methods (3D) demonstrated greater homogeneity than the manual method in analyzing facial distortions caused by the same swelling simulation. Therefore, it can be affirmed that digital methods may be more reliable that manual methods for assessing facial edema.


Assuntos
Imageamento Tridimensional , Fotogrametria , Humanos , Imageamento Tridimensional/métodos , Estudos Transversais , Estudos Prospectivos , Simulação por Computador , Edema/diagnóstico
2.
J Craniofac Surg ; 34(4): 1165-1169, 2023 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-36253326

RESUMO

Cephalometric tracing done manually was considered gold standard for the cephalometric analysis in the last decades. The digital radiographs began to be commonly used in order to make that in a digital way. The objective was to define the accuracy of the predictive and final cephalometric tracings performed manually and virtually. The authors selected 20 patients submitted to bimaxillary orthognathic surgery. The data were collected from lateral cephalometric radiographs, in the preoperative and postoperative periods. The interest were: points, angles (Sella-Nasion to A point angle; Sella-Nasion to B point angle; Frankfurt plane to Mandibular plane angle; Frankfurt plane to occlusal plane angle; Upper and lower central incisors long axes angle; Incisor to Mandibular plane angle; Upper incisor axis to Sella-Nasion plane angle) distances (Co-A; Co-Gn). Data were submitted to the Shapiro-Wilk, analysis of variance, and Kruskal-Wallis tests. The measurement differences were compared using a t test. Descriptive statistics were performed in Excel 2013 and SPSS software, P <0.05 being considered significant. No statistically significant difference was found between the mean values predictive and postoperative of the angles and distances within the manual and digital groups. When comparing the means of the differences between the predictive values and the final values, only the 1:1 angle presented a statistically significant difference, indicating a greater accuracy of the digital predictive tracing for this measure. In conclusion, both methods for obtaining predictive tracings are accurate, which shows that clinical results can be successfully simulated by the most accessible technique.


Assuntos
Cirurgia Ortognática , Humanos , Ossos Faciais , Cefalometria/métodos , Oclusão Dentária , Radiografia , Mandíbula/diagnóstico por imagem , Mandíbula/cirurgia
3.
J Craniofac Surg ; 33(8): e820-e822, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36409857

RESUMO

Nasotracheal intubation is the preferred route for general anesthesia maintenance in patients undergoing maxillofacial surgery or dental procedures. However, compression of the tracheal tube may cause superficial necrosis of the nasal wing and deformation of the external nose. Thus, proper fixation of the tracheal tube during nasotracheal intubation is important for the patient's safety as well as that of the medical staff. Recently, a nasotracheal tube support device has been developed; thus, in this study, the aim was to present and describe the Sverzut nasotracheal tube support device and discuss the advantages of its use during nasal intubation in cervicomaxillofacial surgery. Findings from this study show that the Sverzut nasotracheal tube support device can contribute to the stabilization of the nasotracheal tube and all its connectors, aiding in the maintenance of the airway patency and minimizing the complications related to this type of intubation.


Assuntos
Anestesia Geral , Intubação Intratraqueal , Humanos , Intubação Intratraqueal/métodos , Nariz , Respiração Artificial , Ergonomia
4.
Oral Maxillofac Surg ; 25(4): 541-547, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33715054

RESUMO

PURPOSE: This study aimed to compare the three-dimensional volumetric changes of human maxillary sinuses after reconstruction using 5 different bone grafts. PATIENTS AND METHODS: Patients underwent unilateral maxillary sinus bone height reconstruction using 5 bone substitutes allocated in different groups as follows: group 1 was grafted with autogenous bone graft alone; group 2 with beta-tricalcium phosphate (ß-TCP); group 3 with ß-TCP + autogenous bone graft 1:1; group 4 with bioactive glass; and group 5 with bioactive glass + autogenous bone graft 1:1. The patients were submitted to cone beam computed tomography in two periods: 15 days after the surgical procedure (T1) and after 6 months (T2). The results were evaluated as the formula T2-T1 expressing the three-volumetric changes of the biomaterials in elapsed time. RESULTS: The resorption rate of autogenous bone graft was -630.699 ± 300.9 mm3; in the ß-TCP group, it was -315.772 ± 125.6 mm3; in the group with ß-TCP + autogenous bone graft 1:1, it was -336.205 ± 195.7 mm3; and in groups with bioactive glass and with the addition of autogenous bone graft 1:1, it was -428.878 ± 311.6 mm3 and -576.917 ± 471.6 mm3, respectively, without statistical difference (p = 0.167). Pearson's correlated test revealed a strong correlation as well as a progressive resorption of the grafts during bone healing. CONCLUSION: The similar outcomes for the three-dimensional volumetric changes using the bone substitutes evaluated after 6 months of bone healing suggest that all these grafts can be performed to maxillary sinus reconstruction.


Assuntos
Seio Maxilar , Levantamento do Assoalho do Seio Maxilar , Transplante Ósseo , Humanos , Maxila/diagnóstico por imagem , Maxila/cirurgia , Seio Maxilar/diagnóstico por imagem , Seio Maxilar/cirurgia , Estudos Prospectivos
5.
J Craniofac Surg ; 32(1): e38-e41, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33394635

RESUMO

ABSTRACT: The presence of a tooth in the nasal cavity is a rare condition. There is an even more rare association, which is the presence with the mineral's deposition and formation of rhinoliths. This report shows a case of rare nasal tooth associated with rhinolithiasis and describes its surgical treatment based on an algorithm. The diagnosis was made by endoscopy with the aid of computed tomography, followed by surgical endoscopy excision. The algorithm and the proposed treatment was successful in its execution and the patient presents no complaints or complications at 3 years after surgery.


Assuntos
Doenças Nasais , Dente Supranumerário , Algoritmos , Endoscopia , Humanos , Cavidade Nasal , Nariz , Dente Supranumerário/diagnóstico por imagem , Dente Supranumerário/cirurgia
6.
J Craniofac Surg ; 32(4): e345-e346, 2021 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-33170824

RESUMO

ABSTRACT: Craniofacial harpoon injuries are extremely rare, especially when caused by attempted suicide. The approach to surgical removal becomes dependent on the characteristics of the device, with or without barbs on the spear, and its path, which presents with significant changes between accidents and suicide attempts. This report presents the successful treatment carried out in a dramatic case of harpoon suicide attempt. The approaches to complete and cautious removal of the spear from the occipital region, reconstruction of the orbital cavity, evisceration of the left eyeball due to amaurosis and psychiatric follow-up were successful, which allowed the restoration of the patient's physical and mental health.


Assuntos
Tentativa de Suicídio , Humanos , Fatores de Risco
7.
J. appl. oral sci ; 29: e20200568, 2021. tab, graf
Artigo em Inglês | LILACS, BBO - Odontologia | ID: biblio-1143153

RESUMO

Abstract Objective The aim of this study is to evaluate the new bone and connective tissue formation and the biomaterial remaining after maxillary sinus bone augmentation using 5 different bone substitutes. The osteocalcin immunolabeling was performed to demonstrate their calcification and the possibility of receiving dental implants. Methodology 40 patients underwent maxillary sinus bone augmentation and were divided in 5 groups: Group 1 with 8 maxillary sinuses were grafted with autogenous bone graft (AB); Group 2 with 8 maxillary sinuses grafted with bioactive glass (BG); Group 3 with 8 maxillary sinuses grafted with bioactive glass added to autogenous bone graft (BG + AB) 1:1; Group 4 with 8 maxillary sinuses grafted with Bio-Oss (BO) and Group 5 with 8 maxillary sinuses grafted with Bio-Oss added to autogenous bone graft (BO + AB) 1:1. Results In group AB, 37.8% of bone was formed in the pristine bone region, 38.1% in the intermediate and 44.5% in the apical region. In group BG, 43.6% was formed in the pristine bone, 37% in the intermediate and 49.3% in the apical region. In group BG + AB 1:1, 39.0% was formed in the pristine bone region, 34.8% in the intermediate and 36.8% in apical region. In group BO, 33.4% was formed in the pristine bone, 32.5% in the intermediate and 34.3% in the apical region. In group BO + AB 1:1, 32.8% was formed in the pristine bone, 36.1% in intermediate and 27.8% in the apical regions. The immunolabeling for osteocalcin showed an intensive staining for all groups, which could demonstrate the calcification of the bone formed. Conclusion This study showed that the groups evaluated formed a suitable lamellar bone in the maxillary sinus reconstruction after six months of bone healing, thus being indicated to receive dental implants.


Assuntos
Humanos , Osteogênese , Implantes Dentários , Transplante Ósseo , Substitutos Ósseos , Levantamento do Assoalho do Seio Maxilar , Implantação Dentária Endóssea , Seio Maxilar/cirurgia , Seio Maxilar/diagnóstico por imagem
8.
J Craniofac Surg ; 31(6): e593-e595, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32604308

RESUMO

Toxic epidermal necrolyses represent a severe epidermolytic reaction characterized by cutaneous erythema and target lesions affecting >30% of the body surface, skin, and mucous membranes. Ulcerative lesions on the labial mucosa may evolve during healing, resulting in rare complications, such as lip adhesions. This report shows the successful treatment of a lip synechia resulting from the healing of mucosal lesions in a patient with toxic epidermal necrolysis caused by the use of Lamotrigine and Ibuprofen. Although the treatment of the presented lip synechia was simple, this sequela can be avoided by measures such as hydration, hygiene and lip lubrication.


Assuntos
Síndrome de Stevens-Johnson/complicações , Aderências Teciduais/etiologia , Adulto , Humanos , Lábio/patologia , Síndrome de Stevens-Johnson/patologia , Úlcera/etiologia
9.
J Craniofac Surg ; 31(5): e469-e471, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32282672

RESUMO

Orbital trapdoor fractures are characterized by tissue entrapment between the fractured bone fragment and the remnant of the orbital floor. This entrapment can result in immediate local and systemic complications and poor outcomes when approached late. This article presents the case of an orbital floor fracture in a child with dystopia, pain, edema and entrapment of the inferior rectus muscle and consequent limitation of ocular motility. The strategy proposed in the early approach to orbital floor reconstruction and release of incarcerated tissue allowed the patient to achieve satisfactory results without morbidity, as compared to the outcomes of corrective sequel surgery.


Assuntos
Fraturas Orbitárias/cirurgia , Criança , Movimentos Oculares , Humanos , Masculino , Músculos Oculomotores/cirurgia , Fraturas Orbitárias/diagnóstico por imagem , Prognóstico , Tomografia Computadorizada por Raios X
10.
J Craniofac Surg ; 31(6): e538-e539, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-31977687

RESUMO

Osteoma is the most frequent benign tumor in the craniomaxillofacial region. The most common initial manifestation is facial pressure or headache.The clinical examination showed increased volume in the right supraorbital region, asymmetry of the orbital contour, exophthalmia, dystopia, proptosis and clinical restraint of ocular movement for supraversion. The lesion measured approximately 4 cm in diameter with irregular contour. Osteotomy was performed with saw surrounding the tumor, with aid of a surgical piezo on the orbital medial wall.The result of histopathological examination was osteoma. The patient is 2.5 years postoperatively and so far without complications.


Assuntos
Osteoma/cirurgia , Osteotomia , Neoplasias Cranianas/cirurgia , Adulto , Exoftalmia , Humanos , Masculino , Órbita/diagnóstico por imagem , Órbita/patologia , Órbita/cirurgia , Osteoma/diagnóstico por imagem , Exame Físico , Neoplasias Cranianas/diagnóstico por imagem
11.
J Craniofac Surg ; 31(3): e222-e224, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-31856134

RESUMO

Zygomatic-coronoid ankylosis is a rare complication in maxillofacial trauma. Currently, less of 30 cases reported in the literature. The aim of this study was to report a case of zygomatic-coronoid ankylosis after trauma. A 26-year-old male, with zygomatic-coronoid ankylosis after 7 years of facial trauma, was treated by intraoral bilateral coronoidectomy. However, the literature continues to discuss the best approach, intraorally or extraorally. This study observed that the intraoral approach was easily performed and without complications.


Assuntos
Anquilose Dental/cirurgia , Zigoma/cirurgia , Adulto , Humanos , Masculino , Osteotomia Mandibular , Traumatismos Maxilofaciais/cirurgia
13.
Clin Implant Dent Relat Res ; 21(4): 753-757, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31094060

RESUMO

BACKGROUND: Autogenous bone grafts are the most favorable and predictable types of bone graft due to their osteogenic, osteoinductive, and osteoconductive properties. The advantages of harvesting from mandibular bone are that it requires only local anesthesia, is less invasive, has less morbidity, and avoids harvesting from distant sites, thus making it the best choice for maxillary bone reconstruction. PURPOSE: The aim of this study was to evaluate inferior alveolar nerve (IAN) neurosensory disturbances after autogenous bone graft harvesting from the mandibular symphysis and retromolar region to reconstruct maxillary sinus height for posterior dental implant placement and the effect of these disturbances on patient satisfaction. MATERIALS AND METHODS: Fifty-four patients were invited to participate in this study. Autogenous bone graft was harvested from the mandibular symphysis and retromolar regions. After the procedure, the patients were evaluated by means of an adapted questionnaire to determine if they had complaints of neurosensory disturbances at the following time intervals: immediately, 1, 2-5, 6, 7-11, and 12 months postsurgery. RESULTS: Immediately after surgery, 28 patients described sensory changes and 25 reported paresthesia of inferior lip. Only three patients reported pain, and one patient experienced dental hypersensitivity after the surgical procedure. During the evaluation period, the patients reported a decrease in paresthesia and a return of sensation to areas innervated by the IAN. After 12 months, five patients still reported paresthesia of areas innervated by the IAN. Beside this, patients reported significant clinical improvement from the beginning of the evaluation, as 49 patients were satisfied with their treatment outcomes. CONCLUSION: Harvesting bone grafts from the mandibular symphysis results in greater postoperative morbidity upon immediate evaluation compared with bone graft harvesting from the retromolar region. Nevertheless, during clinical follow-up, the results of both treatments showed that sensation was eventually recovered, depending on the healing period.


Assuntos
Aumento do Rebordo Alveolar , Coleta de Tecidos e Órgãos , Transplante Ósseo , Humanos , Mandíbula , Maxila , Estudos Prospectivos
14.
J Craniofac Surg ; 30(4): 1016-1021, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-30908445

RESUMO

This study aimed to assess the repair of surgically created bone defects filled with blood clot, autogenous bone, and calcium phosphate cement, by histomorphometric and immunohistochemical analyses. Ten adult male rabbits were used. Three bone defects were prepared with an 8-mm diameter trephine bur in the parietal region of each animal and filled with blood clot (Group BC), autogenous bone (Group AB), and calcium phosphate bone cement (Group CPC). The animals were euthanized at 40 and 90 postoperative days. The sections were subjected to histomorphometric analysis of the new bone formed inside the calvarial defects and immunohistochemical staining to determine the expression of osteocalcin (OC), osteopontin (OP), and tartrate-resistant acid phosphatase (TRAP) proteins. Histomorphometric data were analyzed statistically by analysis of variance and Tukey's post hoc test at 5% significance level. In the results at 40 and 90 days, Group AB differed significantly from Group CPC regarding the area of newly formed bone. The immunohistochemical analysis revealed expression of OP, OC, and TRAP proteins in all groups. Group AB showed prevalence of OC and OP, and lower TRAP expression. Therefore, the calcium phosphate bone cement assessed in the present study did not accelerate the protein expression dynamics during bone healing, compared with the autogenous group.


Assuntos
Cimentos Ósseos , Regeneração Óssea/efeitos dos fármacos , Fosfatos de Cálcio/farmacologia , Crânio/patologia , Animais , Materiais Biocompatíveis , Substitutos Ósseos/farmacologia , Transplante Ósseo , Modelos Animais de Doenças , Imuno-Histoquímica , Masculino , Coelhos , Distribuição Aleatória , Crânio/efeitos dos fármacos , Trombose , Cicatrização/efeitos dos fármacos
17.
J Appl Oral Sci ; 26: e20170296, 2018 Jun 11.
Artigo em Inglês | MEDLINE | ID: mdl-29898173

RESUMO

OBJECTIVE: The aim of this study was to compare the bone resorption rate, histomorphometry and immunohistochemical findings of bioactive glass (Biogran; Biomet, Warsaw, IN, USA) mixed with autogenous bone grafts (1:1) and autogenous bone graft isolate in maxillary sinus elevation surgery. MATERIAL AND METHODS: A total of 9 maxillary sinuses were grafted with Biogran with autogenous bone graft (group 1) and 12 were mixed with autogenous bone graft (group 2). Postoperative cone beam computed tomography (CBCT) was used to measure the initial graft volume after 15 days (T1), and 6 months later, another CBCT scan was performed to evaluate the final graft volume (T2) and determine the graft resorption rate. The resorption outcomes were 37.9%±18.9% in group 1 and 45.7%±18.5% in group 2 (P=0.82). After 6 months, biopsies were obtained concurrent with the placement of dental implants; these implants were subjected to histomorphometric analysis and immunohistochemical analysis for tartrate-resistant acid phosphatase (TRAP). RESULTS: The average bone formation in group 1 was 36.6%±12.9 in the pristine bone region, 33.2%±13.3 in the intermediate region, and 45.8%±13.8 in the apical region; in group 2, the values were 34.4%±14.4, 35.0%±13.9, and 42.0%±16.6 of new bone formation in the pristine bone, intermediate, and apical regions, respectively. Immunostaining for TRAP showed poor clastic activity in both groups, which can indicate that those were in the remodeling phase. CONCLUSIONS: The similarity between the groups in the formation and maintenance of the graft volume after 6 months suggests that the bioactive glass mixed with autogenous bone (1:1) can be used safely as a bone substitute for the maxillary sinus lift.


Assuntos
Perda do Osso Alveolar/patologia , Substitutos Ósseos/química , Substitutos Ósseos/uso terapêutico , Transplante Ósseo , Vidro/química , Seio Maxilar/cirurgia , Levantamento do Assoalho do Seio Maxilar/métodos , Regeneração Óssea/fisiologia , Tomografia Computadorizada de Feixe Cônico , Humanos , Imuno-Histoquímica , Seio Maxilar/patologia , Osteogênese/fisiologia , Estudos Prospectivos , Reprodutibilidade dos Testes , Estatísticas não Paramétricas , Fatores de Tempo , Transplante Autólogo/métodos , Resultado do Tratamento
18.
Oral Maxillofac Surg ; 22(2): 231-233, 2018 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-29455344

RESUMO

The removal of displaced dental elements from deep anatomical spaces is a condition that requires the knowledge of the region and skills to perform the procedure. The lateral pharyngeal space contains important structures such as the internal carotid artery and close proximity with the cranium basis. The aim of this paper is to report a clinical case of a lower third molar displaced to the lateral pharyngeal space after a mandibular angle fracture and its treatment by surgical intervention. The tooth was removed under general anesthesia by direct approach and the fracture was reduced and fixed with a plate and screws. This case report illustrates the importance of an immediate procedure to avoiding severe complications and further damage to important anatomical structures.


Assuntos
Fraturas Mandibulares/cirurgia , Dente Serotino/anatomia & histologia , Dente Serotino/cirurgia , Faringe/anatomia & histologia , Extração Dentária/métodos , Dente Impactado/cirurgia , Adulto , Placas Ósseas , Parafusos Ósseos , Brasil , Feminino , Fixação de Fratura/métodos , Humanos , Complicações Intraoperatórias , Fraturas Mandibulares/diagnóstico por imagem , Dente Serotino/diagnóstico por imagem , Base do Crânio , Tomografia Computadorizada por Raios X , Dente Impactado/complicações , Adulto Jovem
19.
J Craniofac Surg ; 29(2): e133-e135, 2018 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-29215444

RESUMO

Varied factors, whether intrinsic or extrinsic, may lead to a decrease in the bone volume of the jaws. Trauma and pathology can be listed as examples of such factors. The aim of this study is to present the osteogenic distraction technique as alternative to augmentation of low mandibular bone volume caused by different etiologies. The first case reports a mandibular marginal resection of ameloblastoma and the second one reports a male patient presenting mandibular fracture sequelae. Both cases were treated according to the osteogenic distraction technique. Several factors have influence on the decision of treatment management of these conditions. Although autogenous bonegraft is considered criterion standard for alveolar reconstruction, its high rates of resorption and the morbidity associated to donor sites lead surgeons to seek for other surgical alternatives such as osteogenic distraction. Therefore, it also aims to expose the advantages and benefits of this technique as well as the satisfactory results achieved.


Assuntos
Ameloblastoma/cirurgia , Fraturas Mandibulares/cirurgia , Neoplasias Mandibulares/cirurgia , Reconstrução Mandibular/métodos , Osteogênese por Distração/métodos , Adulto , Feminino , Humanos , Masculino
20.
J Oral Maxillofac Surg ; 76(2): 325-335, 2018 02.
Artigo em Inglês | MEDLINE | ID: mdl-29100829

RESUMO

PURPOSE: The aim of this study was to compare ChronOS (ß-tricalcium phosphate), Bio-Oss, and their addition to an autogenous bone graft in a 1:1 ratio in human maxillary sinus bone augmentation. MATERIALS AND METHODS: Thirty maxillary sinuses were divided in 5 groups: group 1 included 6 maxillary sinuses grafted with autogenous bone graft alone; group 2 included 6 maxillary sinuses grafted with ChronOS; group 3 included 6 maxillary sinuses grafted with ChronOS and autogenous bone graft in a 1:1 ratio; group 4 included 6 maxillary sinuses grafted with Bio-Oss; and group 5 included 6 maxillary sinuses grafted with Bio-Oss and autogenous bone graft in a 1:1 ratio. The number of samples for each group was determined by the statistical power test. RESULTS: The median areas of new bone formation in groups 1, 2, 3, 4, and 5 were 121,917.0, 83,787.0, 99,295.0, 65,717.0, and 56,230.0 µm2, respectively. Statistically significant differences were found between groups 3 and 5, groups 1 and 4, and groups 1 and 5 (P < .05). The median areas of remaining biomaterial were 2,900.5, 5,291.0, 2,662.0, 56,258.5, and 64,753.5 µm2 in groups 1, 2, 3, 4 and 5, respectively. Statistically significant differences occurred between groups 1 and 5, groups 3 and 5, and groups 2 and 5 (P < .05). Areas of connective tissue were 67,829.0 ± 22,984.6 µm2 in group 1, 97,445.9 ± 18,983.3 µm2 in group 2, 88,256.0 ± 21,820.5 µm2 in group 3, 65,501.8 ± 6,297.6 in group 4, and 70,203.2 ± 13,421.3 µm2 in group 5. CONCLUSIONS: ChronOS combined with autogenous bone graft presented a behavior similar to that of autogenous bone graft alone. However, the groups treated with Bio-Oss showed immuno-labeling results indicating maturation of grafted bone.


Assuntos
Substitutos Ósseos/farmacologia , Transplante Ósseo/métodos , Fosfatos de Cálcio/farmacologia , Minerais/farmacologia , Levantamento do Assoalho do Seio Maxilar/métodos , Subunidade alfa 1 de Fator de Ligação ao Core/metabolismo , Humanos , Imuno-Histoquímica , Osteocalcina/metabolismo , Estudos Prospectivos , Fator A de Crescimento do Endotélio Vascular/metabolismo
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